GO:0004035

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Name alkaline phosphatase activity
Categary Function
Go Slim No
Go Link GO:0004035
Unique Molecular Interactions 45
Total Molecular Interactions 61
Total Single Events 1480
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for alkaline phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported for alkaline phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT218933 Cyp3a23/3a1 Regulation of Alpi 1 0.00 1.07 0.73
2 INT233104 Akp1 Negative_regulation of Localization of VMO1 1 0.14 0.61 0.61
3 INT218932 Cyp3a23/3a1 Regulation of Gene_expression of Alpi 1 0.00 0.53 0.46
4 INT155058 Stat3 Negative_regulation of Akp3 1 0.01 3.7 0.33
5 INT343571 Synm Positive_regulation of ALPP 1 0.01 1.28 0.28
6 INT218931 Cyp3a23/3a1 Regulation of Gene_expression of Akp3 1 0.00 0.55 0.27
7 INT155059 Csf2 Negative_regulation of Akp3 1 0.00 1.88 0.17
8 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13
9 INT334044 Cdt1 Regulation of Gene_expression of ALPP 1 0.04 0.72 0.12
10 INT196444 Binding of ALPP and ALPPL2 1 0.17 0.59 0.1
11 INT354925 ALB Positive_regulation of ALPP 1 0.34 1.69 0.09
12 INT334043 Cdt1 Positive_regulation of Gene_expression of ALPP 1 0.08 0.39 0.05
13 INT225806 Il1 Regulation of ALPI 1 0.00 0.44 0.05
14 INT319578 CYP3A4 Regulation of ALPPL2 1 0.00 0.56 0.05
15 INT212013 RAD51D Negative_regulation of ALPP 1 0.00 0.7 0
16 INT196439 ALPPL2 Regulation of Localization of ALPP 1 0.21 0.65 0
17 INT184824 ALPP Regulation of Fig4 1 0.04 0 0
18 INT341666 ALPI Positive_regulation of ENPEP 1 0.01 1.05 0
19 INT196038 Gene_expression of Bmp7 Positive_regulation of ALPP 1 0.03 0.1 0
20 INT260577 Binding of ALPP and SGSM3 1 0.00 1.06 0
21 INT225807 Enpp2 Positive_regulation of ALPI 1 0.00 0.23 0
22 INT196441 Binding of ALPP and PAEP 1 0.02 0 0
23 INT188164 Binding of ALPP and HIVEP1 1 0.02 1.15 0
24 INT281990 Binding of ALPP and Ik 1 0.02 0.29 0
25 INT171572 Binding of ALPP and IGHG3 1 0.01 0.41 0
26 INT251928 GOPC Regulation of Gene_expression of ALPP 1 0.06 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for alkaline phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported in alkaline phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18
2 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1
3 INT10094 Negative_regulation of ALPP 36 0.37 20.45 6.45
4 INT34592 Positive_regulation of Gene_expression of ALPP 51 0.67 20.62 5.68
5 INT4342 Localization of ALPP 27 0.69 15.19 5.32
6 INT85776 Binding of Akp1 5 0.30 4.64 3.77
7 INT34591 Regulation of Localization of ALPP 5 0.53 1.81 2.86
8 INT64797 Regulation of ALPP 18 0.24 9.71 2.24
9 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15
10 INT27222 Gene_expression of ALPPL2 4 0.52 24.57 2.05
11 INT159497 Gene_expression of Akp1 4 0.55 2.2 1.89
12 INT131916 Negative_regulation of ALPL 10 0.42 9.33 1.8
13 INT12775 Negative_regulation of Akp1 4 0.16 2.28 1.73
14 INT181316 Positive_regulation of ALPL 5 0.65 1.65 1.6
15 INT108798 Negative_regulation of Positive_regulation of ALPP 9 0.25 4.26 1.46
16 INT34594 Negative_regulation of Gene_expression of ALPP 12 0.50 5.04 1.41
17 INT85775 Positive_regulation of Akp1 2 0.20 1.5 1.41
18 INT195060 Gene_expression of ALPL 9 0.73 4.82 1.3
19 INT218916 Gene_expression of Alpi 4 0.10 2.31 1.05
20 INT108800 Negative_regulation of ALPPL2 2 0.28 1.83 0.99
21 INT54438 Binding of ALPP 25 0.39 14.02 0.96
22 INT108797 Positive_regulation of Negative_regulation of ALPP 1 0.30 0.23 0.96
23 INT67038 Positive_regulation of Positive_regulation of ALPP 5 0.08 2.61 0.77
24 INT11657 Gene_expression of ALPI 11 0.71 5.13 0.74
25 INT34593 Negative_regulation of Localization of ALPP 2 0.50 0.85 0.64
26 INT108799 Regulation of Gene_expression of ALPP 9 0.27 2.98 0.62
27 INT188166 Transcription of ALPP 9 0.56 4.34 0.62
28 INT4238 Negative_regulation of ALPI 7 0.58 3.31 0.62
29 INT233099 Localization of Akp1 1 0.28 0.61 0.61
30 INT218915 Positive_regulation of Transcription of Alpi 1 0.09 1.04 0.58
31 INT218911 Transcription of Alpi 1 0.10 1.07 0.55
32 INT218908 Gene_expression of Akp3 1 0.11 1.45 0.53
33 INT40583 Regulation of ALPI 4 0.45 1.87 0.48
34 INT81577 Regulation of ALPL 3 0.26 0.82 0.48
35 INT155057 Transcription of Akp3 2 0.11 1.91 0.46
36 INT218924 Regulation of Alpi 1 0.06 0.52 0.45
37 INT184413 Phosphorylation of ALPP 3 0.76 2.42 0.43
38 INT195058 Positive_regulation of Gene_expression of ALPL 3 0.65 1.56 0.42
39 INT195059 Phosphorylation of ALPL 1 0.77 0.79 0.4
40 INT184823 Positive_regulation of Localization of ALPP 3 0.10 0.85 0.31
41 INT97118 Localization of ALPI 2 0.61 1.37 0.3
42 INT218912 Positive_regulation of Transcription of Akp3 1 0.07 0.52 0.28
43 INT218913 Regulation of Transcription of Alpi 1 0.06 0.56 0.28
44 INT218907 Regulation of Gene_expression of Akp3 1 0.07 0.55 0.27
45 INT27223 Positive_regulation of ALPPL2 1 0.20 0.08 0.25
46 INT209397 Transcription of ALPI 2 0.55 1.18 0.24
47 INT196461 Binding of ALPPL2 1 0.32 4.1 0.2
48 INT196468 Protein_catabolism of ALPP 3 0.34 0.31 0.18
49 INT28941 Binding of ALPI 2 0.37 1.13 0.18
50 INT218909 Regulation of Akp3 1 0.07 1.15 0.17
51 INT218926 Negative_regulation of Alpi 1 0.08 1.12 0.16
52 INT218921 Negative_regulation of Akp3 1 0.09 1.13 0.16
53 INT298576 Negative_regulation of Negative_regulation of ALPP 1 0.05 1.82 0.12
54 INT57633 Positive_regulation of Gene_expression of ALPI 2 0.64 1.65 0.1
55 INT196469 Negative_regulation of Gene_expression of ALPPL2 1 0.28 3.43 0.1
56 INT107209 Negative_regulation of Positive_regulation of ALPI 1 0.33 0.45 0.1
57 INT196464 Localization of ALPPL2 1 0.50 2.22 0.09
58 INT196472 Transcription of ALPPL2 1 0.46 0.95 0.07
59 INT225803 Regulation of Gene_expression of ALPI 1 0.01 0.53 0.06
60 INT196475 Positive_regulation of Gene_expression of ALPPL2 1 0.33 2.3 0.03
61 INT196466 Negative_regulation of Binding of ALPP 1 0.25 0 0
62 INT188167 Negative_regulation of Transcription of ALPP 1 0.35 0.64 0
63 INT196470 Regulation of ALPPL2 1 0.30 2.21 0
64 INT196462 Regulation of Negative_regulation of ALPP 1 0.23 0.16 0
65 INT196473 Regulation of Gene_expression of ALPPL2 1 0.30 1.96 0
66 INT201198 Positive_regulation of Alpi 1 0.45 0 0
67 INT218745 Regulation of Gene_expression of ALPL 1 0.44 0.31 0
68 INT196465 Regulation of Negative_regulation of ALPPL2 1 0.30 0.16 0
69 INT196463 Negative_regulation of Binding of ALPPL2 1 0.28 0 0
70 INT223675 Positive_regulation of Localization of ALPI 1 0.01 0.16 0
71 INT196474 Positive_regulation of Binding of ALPP 1 0.26 0.56 0
72 INT195057 Binding of ALPL 1 0.40 0.05 0
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