GO:0004052

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Name arachidonate 12-lipoxygenase activity
Categary Function
Go Slim No
Go Link GO:0004052
Unique Molecular Interactions 10
Total Molecular Interactions 10
Total Single Events 111
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for arachidonate 12-lipoxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for arachidonate 12-lipoxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
2 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
3 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
4 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
5 INT343157 ACSL4 Regulation of Gene_expression of ALOX15 1 0.01 0.67 0.07
6 INT313508 Binding of ALOX12 and CRP 1 0.06 0.44 0.03
7 INT313552 Binding of ALOX12 and Cor 1 0.01 0.99 0.03
8 INT343164 ACSL4 Regulation of Positive_regulation of ALOX15 1 0.01 1.08 0.03
9 INT313501 Binding of ALOX12 and ICAM1 1 0.10 0.54 0.03
10 INT343158 ACSL4 Regulation of Regulation of ALOX15 1 0.01 0.47 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for arachidonate 12-lipoxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in arachidonate 12-lipoxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT71002 Gene_expression of ALOX15 21 0.78 21.16 6.37
2 INT93079 Positive_regulation of ALOX15 8 0.70 12.46 6.22
3 INT18523 Negative_regulation of ALOX15 15 0.59 14.2 5.92
4 INT89606 Positive_regulation of Gene_expression of ALOX15 9 0.70 8.34 3.76
5 INT101257 Negative_regulation of Positive_regulation of ALOX15 1 0.41 1.47 1.71
6 INT126635 Negative_regulation of Alox15 2 0.41 0.67 1.43
7 INT101256 Regulation of ALOX15 3 0.26 2.44 1.02
8 INT89607 Negative_regulation of Negative_regulation of ALOX15 3 0.43 2.08 0.68
9 INT89605 Negative_regulation of Gene_expression of ALOX15 8 0.59 4.03 0.61
10 INT27543 Positive_regulation of ALOX12 1 0.09 2.09 0.48
11 INT198335 Regulation of ALOX12 1 0.00 0.11 0.1
12 INT150032 Gene_expression of ALOX12 7 0.65 0.61 0.09
13 INT188645 Binding of ALOX12 2 0.30 3.07 0.09
14 INT327064 Localization of ALOX15 1 0.65 0.86 0.09
15 INT150031 Negative_regulation of Gene_expression of ALOX12 2 0.41 0.05 0.07
16 INT150033 Negative_regulation of ALOX12 1 0.57 0.05 0.07
17 INT150030 Negative_regulation of Gene_expression of Alox15 1 0.11 0.05 0.07
18 INT150029 Gene_expression of Alox15 1 0.18 0 0.04
19 INT313548 Phosphorylation of ALOX12 1 0.57 0.12 0
20 INT313541 Negative_regulation of Phosphorylation of ALOX12 1 0.30 0.18 0
21 INT343176 Regulation of Gene_expression of ALOX15 1 0.01 1.05 0
22 INT313550 Positive_regulation of Gene_expression of ALOX12 1 0.35 0.43 0
23 INT327065 Binding of ALOX15 1 0.31 0.17 0
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