GO:0004058

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Name aromatic-L-amino-acid decarboxylase activity
Categary Function
Go Slim No
Go Link GO:0004058
Unique Molecular Interactions 60
Total Molecular Interactions 66
Total Single Events 598
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for aromatic-L-amino-acid decarboxylase activity. They are ordered first by their pain relevance and then by number of times they were reported for aromatic-L-amino-acid decarboxylase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT60827 Ddc Positive_regulation of Localization of Abat 1 0.12 0.34 0.94
2 INT60828 Ddc Positive_regulation of Abat 1 0.13 0.34 0.93
3 INT272039 Ddc Positive_regulation of Gene_expression of Aanat 1 0.00 0.26 0.87
4 INT99937 Ddc Regulation of Transcription of Qrfp 1 0.02 0 0.69
5 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66
6 INT50634 Ddc Regulation of Gene_expression of Glul 1 0.02 0 0.65
7 INT127057 Ddc Positive_regulation of Gene_expression of Slc1a2 1 0.01 0.06 0.63
8 INT113146 Ddc Positive_regulation of Gene_expression of Nr4a1 1 0.06 0.1 0.63
9 INT127056 Ddc Positive_regulation of Transcription of Drd3 1 0.10 0.06 0.63
10 INT281124 Tcf21 Positive_regulation of Binding of Ddc 1 0.04 1.21 0.54
11 INT56733 Ddc Positive_regulation of Localization of GLUL 1 0.00 0 0.54
12 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
13 INT64639 Slc1a1 Positive_regulation of Ddc 1 0.30 0.3 0.38
14 INT50635 Ddc Regulation of Gene_expression of Penk 1 0.03 0 0.38
15 INT281155 Binding of ITIH4 and Ddc 1 0.09 1.27 0.37
16 INT326587 GYPA Regulation of DDC 1 0.08 0.83 0.33
17 INT126097 Ddc Positive_regulation of Egr1 1 0.08 0 0.32
18 INT1757 DDC Regulation of Localization of GH1 1 0.01 0 0.31
19 INT353979 Ddc Positive_regulation of Pet1 1 0.49 0 0.26
20 INT325767 Negative_regulation of Omd Positive_regulation of Ddc 1 0.01 0.38 0.25
21 INT138088 Ddc Regulation of Transcription of Nr4a1 1 0.02 0.16 0.24
22 INT336561 Binding of DDC and DIO2 1 0.04 0.27 0.24
23 INT164 Ddc Negative_regulation of Prl 1 0.06 0 0.23
24 INT342744 Ddc Regulation of Trh 1 0.02 0.37 0.18
25 INT157097 Ddc Positive_regulation of Drd3 1 0.30 0.88 0.16
26 INT99084 Ddc Positive_regulation of Pdyn 2 0.15 0.87 0.14
27 INT99085 Ddc Positive_regulation of Transcription of Pdyn 1 0.15 0.31 0.11
28 INT325766 Binding of Ddc and Omd 1 0.01 0.59 0.04
29 INT105726 Ddc Positive_regulation of Gene_expression of Pdyn 1 0.04 0.62 0.04
30 INT281125 Binding of Ddc and Cd4 1 0.09 0.37 0.03
31 INT129864 Ddc Positive_regulation of Gene_expression of Fosb 1 0.02 0.13 0
32 INT145555 Ddc Positive_regulation of Phosphorylation of Mapk1 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for aromatic-L-amino-acid decarboxylase activity. They are ordered first by their pain relevance and then by number of times they were reported in aromatic-L-amino-acid decarboxylase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67 Negative_regulation of Ddc 66 0.59 15.34 28.96
2 INT6230 Localization of Ddc 40 0.79 13.11 20.88
3 INT9027 Positive_regulation of Ddc 24 0.66 6.04 10.19
4 INT53062 Gene_expression of Ddc 31 0.77 11.59 9.63
5 INT220 Negative_regulation of Ddc 16 0.59 2.94 8.66
6 INT47811 Positive_regulation of Localization of Ddc 11 0.69 4 7.6
7 INT4284 Regulation of Ddc 17 0.43 8.17 7.31
8 INT144735 Gene_expression of DDC 8 0.75 3.21 5.31
9 INT149795 Gene_expression of Ddc 8 0.73 1.5 3.06
10 INT47812 Negative_regulation of Localization of Ddc 5 0.51 1.99 2.8
11 INT16406 Positive_regulation of Negative_regulation of Ddc 6 0.67 0.53 2.6
12 INT14360 Positive_regulation of DDC 7 0.70 2.97 2.02
13 INT157095 Binding of Ddc 5 0.27 4.6 2
14 INT243846 Localization of DDC 3 0.63 0.66 1.99
15 INT82676 Negative_regulation of Gene_expression of Ddc 4 0.55 0.55 1.43
16 INT333291 Positive_regulation of Gene_expression of DDC 1 0.49 0.13 1.35
17 INT121136 Negative_regulation of DDC 4 0.57 2.98 1.32
18 INT4480 Positive_regulation of Ddc 3 0.39 0.53 1.3
19 INT86036 Negative_regulation of Positive_regulation of Ddc 2 0.35 0.42 0.8
20 INT87728 Regulation of Gene_expression of Ddc 4 0.25 1.1 0.71
21 INT258710 Regulation of Negative_regulation of Ddc 2 0.25 1.28 0.66
22 INT232442 Negative_regulation of Gene_expression of DDC 1 0.05 1.44 0.58
23 INT144737 Regulation of Gene_expression of DDC 1 0.06 0 0.49
24 INT258772 Regulation of DDC 1 0.36 0.05 0.4
25 INT325303 Binding of DDC 3 0.30 1.04 0.28
26 INT258091 Localization of Ddc 1 0.08 0.12 0.22
27 INT342740 Positive_regulation of Binding of Ddc 1 0.03 0.1 0.22
28 INT149796 Regulation of Gene_expression of Ddc 2 0.42 0.09 0.21
29 INT184904 Regulation of Ddc 1 0.24 0.06 0.19
30 INT258692 Transcription of Ddc 1 0.67 0.29 0.14
31 INT14359 Regulation of Positive_regulation of DDC 1 0.45 0.92 0.12
32 INT325760 Phosphorylation of Ddc 1 0.27 0.06 0.12
33 INT258696 Negative_regulation of Transcription of Ddc 1 0.55 0.11 0.09
34 INT353974 Negative_regulation of Gene_expression of Ddc 1 0.35 0.21 0.05
35 INT258699 Regulation of Transcription of Ddc 1 0.57 0 0.03
36 INT258702 Positive_regulation of Transcription of Ddc 1 0.43 0.05 0
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