GO:0004065

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Name arylsulfatase activity
Categary Function
Go Slim No
Go Link GO:0004065
Unique Molecular Interactions 32
Total Molecular Interactions 36
Total Single Events 417
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for arylsulfatase activity. They are ordered first by their pain relevance and then by number of times they were reported for arylsulfatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
2 INT124742 ARSA Positive_regulation of Localization of CSF2 1 0.10 0.15 0.91
3 INT124743 ARSA Negative_regulation of PTGER2 1 0.03 0.15 0.85
4 INT124744 ARSA Negative_regulation of Gene_expression of PTGER2 1 0.03 0.15 0.85
5 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
6 INT125543 Arsa Negative_regulation of Phosphorylation of Nfkbia 1 0.00 0.52 0.68
7 INT94075 ARSA Negative_regulation of Gene_expression of IL4 1 0.28 0.26 0.62
8 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59
9 INT125546 Arsa Negative_regulation of Gene_expression of PTGS2 1 0.00 0.53 0.58
10 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
11 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
12 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
13 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
14 INT273893 ARSA Positive_regulation of HSD11B1 1 0.00 0.61 0.4
15 INT187064 ARSD Negative_regulation of CYP19A1 1 0.22 0.7 0.35
16 INT94073 ARSA Negative_regulation of Transcription of IL4 1 0.20 0.16 0.31
17 INT94076 ARSA Negative_regulation of Gene_expression of IL2 1 0.13 0.09 0.3
18 INT94072 ARSA Regulation of Gene_expression of IL2 1 0.07 0.09 0.29
19 INT94074 ARSA Regulation of Gene_expression of IK 1 0.01 0.06 0.27
20 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05
21 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05
22 INT191590 Binding of AMBP and Arsb 1 0.00 1.82 0.04
23 INT254909 ARSH Regulation of Sumf1 1 0.00 0.9 0.04
24 INT254908 ARSH Regulation of Eef1a1 1 0.00 0.89 0.04
25 INT183090 Gene_expression of SULF1 Positive_regulation of Phosphorylation of FGF2 1 0.19 0.42 0
26 INT106380 ARSA Regulation of Gene_expression of BAX 1 0.06 0.12 0
27 INT183093 SULF1 Negative_regulation of Binding of FGF2 1 0.17 0.41 0
28 INT190902 Binding of HBN1 and Arsb 1 0.00 1.88 0
29 INT183134 Binding of SULF1 and Panc1 1 0.03 0.42 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for arylsulfatase activity. They are ordered first by their pain relevance and then by number of times they were reported in arylsulfatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT154229 Gene_expression of ARSD 22 0.57 12.5 6.19
2 INT183119 Gene_expression of SULF1 1 0.75 46.71 5.44
3 INT108501 Binding of ARSD 14 0.32 11.5 2.93
4 INT187073 Positive_regulation of Gene_expression of ARSD 1 0.28 4.49 2.85
5 INT59859 Localization of ARSD 11 0.65 9.67 1.88
6 INT302658 Binding of ARSA 1 0.07 0.92 1.53
7 INT118267 Negative_regulation of ARSD 14 0.36 8.27 1.44
8 INT127670 Positive_regulation of ARSD 8 0.54 1.75 1.33
9 INT202162 Negative_regulation of Localization of ARSD 3 0.28 4.73 1.3
10 INT162831 Regulation of ARSD 13 0.35 6.17 1.19
11 INT43295 Regulation of Arsa 1 0.43 0 1.15
12 INT183127 Localization of SULF1 1 0.77 3.45 1.13
13 INT104298 Negative_regulation of ARSA 2 0.28 0.56 0.89
14 INT176467 Gene_expression of Arsa 1 0.58 2.62 0.83
15 INT96649 Gene_expression of ARSA 5 0.65 2.82 0.8
16 INT302660 Positive_regulation of Gene_expression of ARSA 1 0.10 0.88 0.77
17 INT125542 Phosphorylation of Arsa 1 0.02 0.52 0.67
18 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65
19 INT170284 Gene_expression of Arsb 9 0.65 9.12 0.63
20 INT187076 Negative_regulation of Binding of ARSD 1 0.21 1.11 0.61
21 INT183133 Negative_regulation of Localization of SULF1 1 0.41 1.34 0.59
22 INT104297 Regulation of ARSA 1 0.18 1.05 0.49
23 INT302661 Negative_regulation of Negative_regulation of ARSA 1 0.08 0.13 0.44
24 INT2522 Positive_regulation of ARSH 3 0.11 0.71 0.39
25 INT302663 Positive_regulation of ARSA 1 0.10 0.36 0.38
26 INT183114 Positive_regulation of Gene_expression of SULF1 1 0.48 7.61 0.37
27 INT190900 Binding of Arsb 5 0.35 17.18 0.35
28 INT183116 Positive_regulation of SULF1 1 0.67 3.22 0.34
29 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29
30 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27
31 INT170285 Positive_regulation of Gene_expression of Arsb 1 0.40 0.65 0.21
32 INT243500 Protein_catabolism of ARSD 1 0.69 0.67 0.17
33 INT182865 Localization of ARSA 1 0.24 1.27 0.15
34 INT154230 Regulation of Gene_expression of ARSD 2 0.35 1.01 0.14
35 INT310677 Localization of ARSB 1 0.71 5.72 0.14
36 INT183125 Negative_regulation of SULF1 2 0.42 2.26 0.13
37 INT143770 Binding of ARSH 2 0.23 0.77 0.12
38 INT244122 Negative_regulation of Arsa 1 0.42 0 0.12
39 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12
40 INT3649 Positive_regulation of Arsa 1 0.50 0 0.1
41 INT183124 Regulation of Gene_expression of SULF1 1 0.59 1.92 0.1
42 INT168037 Positive_regulation of Localization of ARSD 1 0.06 0.27 0.08
43 INT183129 Negative_regulation of Gene_expression of SULF1 1 0.56 5.19 0.07
44 INT183122 Regulation of SULF1 1 0.59 1.53 0.06
45 INT318627 Regulation of Arsb 1 0.17 2.74 0.04
46 INT244185 Phosphorylation of ARSD 1 0.53 1.12 0.04
47 INT310678 Protein_catabolism of ARSH 1 0.06 1.76 0.04
48 INT199164 Negative_regulation of Gene_expression of ARSH 1 0.23 0.08 0.04
49 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04
50 INT310682 Regulation of ARSB 1 0.43 0.98 0.04
51 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04
52 INT190901 Negative_regulation of Arsb 2 0.19 2.67 0
53 INT199163 Regulation of ARSH 1 0.25 0.07 0
54 INT239403 Regulation of Negative_regulation of ARSD 1 0.37 0.79 0
55 INT318626 Positive_regulation of Arsb 1 0.32 2.1 0
56 INT318625 Localization of Arsb 1 0.52 2.04 0
57 INT183128 Transcription of SULF1 1 0.66 0.17 0
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