GO:0004089

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Name carbonate dehydratase activity
Categary Function
Go Slim No
Go Link GO:0004089
Unique Molecular Interactions 511
Total Molecular Interactions 654
Total Single Events 7624
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for carbonate dehydratase activity. They are ordered first by their pain relevance and then by number of times they were reported for carbonate dehydratase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT318474 Positive_regulation of OPRM1 Positive_regulation of Localization of CA2 1 0.17 0.55 2.7
2 INT318473 Positive_regulation of OPRM1 Positive_regulation of CA2 1 0.17 0.46 2.13
3 INT296277 Binding of Car2 and Kcnip3 5 0.18 1.09 2.06
4 INT296280 Binding of Car2 and Dlg4 1 0.19 0.45 1.71
5 INT45816 Binding of Car2 and Gabrg1 2 0.28 0.15 1.63
6 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55
7 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
8 INT256360 Car2 Positive_regulation of Localization of Rela 1 0.14 0 1.51
9 INT293009 IRF6 Positive_regulation of Positive_regulation of CA2 1 0.04 0.66 1.49
10 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
11 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21
12 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21
13 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
14 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05
15 INT293014 IRF6 Positive_regulation of Localization of CA2 1 0.04 0.71 1.02
16 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
17 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
18 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98
19 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
20 INT110118 A630055G03Rik Regulation of Car2 1 0.01 0.35 0.81
21 INT270217 Binding of C2 and Ca2 1 0.03 1.63 0.81
22 INT251172 Trpv1 Regulation of Gene_expression of Ca2 1 0.13 0.7 0.81
23 INT296279 Positive_regulation of Rbm39 Positive_regulation of Positive_regulation of Car2 1 0.01 0.58 0.78
24 INT69225 Pnoc Negative_regulation of Car1 1 0.42 0 0.78
25 INT296297 Positive_regulation of Cysltr1 Positive_regulation of Positive_regulation of Car2 1 0.01 0.59 0.77
26 INT170369 Binding of Car2 and Nono 1 0.01 0 0.76
27 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
28 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73
29 INT136538 Nrgn Regulation of Car2 1 0.33 0 0.73
30 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
31 INT296292 Binding of Car1 and Grin2a 1 0.14 0.32 0.72
32 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
33 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71
34 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71
35 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
36 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
37 INT283049 Car2 Positive_regulation of Trpa1 1 0.20 1.33 0.67
38 INT41224 Pdyn Positive_regulation of Car1 1 0.19 0 0.66
39 INT309123 Edc4 Positive_regulation of Car1 1 0.02 0.51 0.66
40 INT308484 Car2 Positive_regulation of Pla2g4a 1 0.03 1.23 0.65
41 INT251165 Trpv1 Positive_regulation of Gene_expression of Ca2 1 0.15 0.54 0.65
42 INT235082 CA2 Positive_regulation of NOS1 2 0.11 0.62 0.63
43 INT326193 Bdnf Positive_regulation of Car2 2 0.14 0.11 0.62
44 INT121873 Creb1 Regulation of Phosphorylation of Car2 1 0.10 0 0.62
45 INT50816 Penk Positive_regulation of Localization of Ca2 1 0.32 0 0.62
46 INT123301 Car2 Positive_regulation of Creb1 1 0.21 0.28 0.61
47 INT70254 Binding of Htr1a and Ca2 1 0.31 0.5 0.6
48 INT275063 CA2 Positive_regulation of Positive_regulation of CAMK4 1 0.01 0 0.59
49 INT240070 KCNIP3 Regulation of CA2 1 0.02 0.72 0.59
50 INT218844 Cysltr1 Regulation of Car1 1 0.01 1.42 0.55
51 INT218839 Ppp1r9a Regulation of Car1 1 0.12 1.42 0.55
52 INT218841 Ltp Regulation of Car1 1 0.15 1.42 0.55
53 INT209591 Car2 Positive_regulation of Positive_regulation of Ltp 1 0.05 0 0.54
54 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54
55 INT209592 Car2 Positive_regulation of Localization of Ltp 1 0.05 0 0.54
56 INT216918 Binding of Ca2 and Abat 1 0.01 0.45 0.53
57 INT118138 Binding of Ca2 and Mgat4a 1 0.01 0 0.53
58 INT187333 Binding of C4bpa and Car1 1 0.08 0 0.52
59 INT297479 Ryr2 Positive_regulation of Ca2 1 0.22 0 0.52
60 INT318472 CA2 Regulation of OPRM1 1 0.17 0 0.51
61 INT330796 P2ry1 Positive_regulation of Ca2 1 0.05 0.06 0.5
62 INT250077 Positive_regulation of Ltp Positive_regulation of Localization of Ca2 1 0.10 0 0.48
63 INT237810 Itpr3 Positive_regulation of Localization of Car2 2 0.08 0.68 0.45
64 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45
65 INT346914 Binding of Kars and Positive_regulation of Gene_expression of Car2 1 0.05 1.24 0.45
66 INT265359 Efs Positive_regulation of Car2 1 0.19 0.42 0.45
67 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
68 INT185191 Binding of Car9 and Pif 1 0.01 2.33 0.45
69 INT309136 Dlat Positive_regulation of Gene_expression of Car1 1 0.03 0.99 0.45
70 INT254460 Binding of Calm2 and Ca2 5 0.03 0.48 0.43
71 INT257806 Binding of Car1 and Gopc 1 0.13 0 0.43
72 INT325701 Aacs Regulation of Car3 1 0.17 0 0.4
73 INT291449 Car2 Positive_regulation of SK 1 0.03 0 0.39
74 INT334662 Ltp Regulation of Car2 1 0.09 0.22 0.39
75 INT168200 Binding of CA1 and Nav1 1 0.11 0 0.39
76 INT15028 NA Positive_regulation of Localization of Ca2 1 0.04 0 0.39
77 INT201274 Car2 Regulation of Gene_expression of Nos1 1 0.05 1.15 0.38
78 INT272148 PTAFR Regulation of Localization of CA2 1 0.14 0 0.38
79 INT235083 CA2 Positive_regulation of Gene_expression of CALM1 1 0.01 0.63 0.37
80 INT33862 Ca2 Positive_regulation of Positive_regulation of Sult1b1 1 0.07 0.07 0.37
81 INT320591 Ca2 Positive_regulation of Nos1 1 0.07 0.09 0.37
82 INT263226 Prkcg Negative_regulation of Positive_regulation of Ca2 1 0.01 0.58 0.36
83 INT26168 Car2 Positive_regulation of Hrasls 1 0.10 0 0.36
84 INT309192 Binding of Car2 and Rbms1 1 0.05 0 0.34
85 INT353689 Binding of Slc8a1 and Ca2 1 0.15 0.58 0.33
86 INT241966 Binding of Ca2 and Acpt 1 0.06 0.06 0.33
87 INT322129 Binding of Prkcg and Ca2 1 0.00 0.57 0.33
88 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33
89 INT34449 Binding of Ca2 and Pck1 1 0.17 0.18 0.33
90 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32
91 INT195146 Cpm Regulation of Localization of CA2 1 0.00 0.22 0.32
92 INT241971 Ca2 Regulation of Localization of Abat 1 0.01 0 0.31
93 INT317557 Calm3 Positive_regulation of Car2 1 0.05 0 0.31
94 INT232614 Positive_regulation of Car2 Positive_regulation of Cysltr1 1 0.01 0.62 0.31
95 INT232616 Car2 Positive_regulation of Cysltr1 1 0.02 0.62 0.31
96 INT156261 Negative_regulation of Binding of Oxt and Ca2 1 0.16 0.12 0.3
97 INT26738 Ca2 Positive_regulation of Localization of Ins1 1 0.12 0.09 0.3
98 INT261047 MZB1 Positive_regulation of Positive_regulation of CA2 1 0.02 0.09 0.3
99 INT156262 Binding of Oxt and Ca2 1 0.14 0.12 0.3
100 INT209233 Tg(Ngf)47Kma Regulation of Car2 1 0.01 0.1 0.28
101 INT209232 Tg(Ngf)47Kma Regulation of Localization of Car2 1 0.02 0.1 0.28
102 INT154834 Stim1 Regulation of Regulation of Ca2 1 0.13 0.9 0.28
103 INT189200 Binding of CA2 and ITPR3 3 0.03 1.9 0.27
104 INT334669 Negative_regulation of Car1 Negative_regulation of Positive_regulation of Psmd1 1 0.13 1.17 0.27
105 INT305623 Ca2 Positive_regulation of Cabin1 1 0.00 0.27 0.27
106 INT322127 Binding of Mbp and Ca2 1 0.01 0.39 0.27
107 INT323147 Binding of CA2 and DBT 1 0.01 0.17 0.26
108 INT250461 Binding of Car2 and Ba2 1 0.01 0 0.26
109 INT272174 Acot1 Regulation of Ca2 1 0.01 0 0.26
110 INT35022 Ptz1b Positive_regulation of Ca2 1 0.01 0 0.25
111 INT35020 Regulation of Ptz1b Positive_regulation of Ca2 1 0.01 0 0.25
112 INT257805 Binding of Car3 and Gopc 1 0.18 0 0.25
113 INT209230 Positive_regulation of Car2 Positive_regulation of Ltp 1 0.04 0.12 0.25
114 INT283028 Nav1 Regulation of Ca2 1 0.08 0 0.24
115 INT283027 Pirt Regulation of Ca2 1 0.00 0 0.24
116 INT130691 CA2 Positive_regulation of EIF2AK3 1 0.16 0.59 0.24
117 INT130714 CA2 Positive_regulation of Eif2s1 1 0.16 0.59 0.24
118 INT309141 Dlat Positive_regulation of Car1 1 0.03 0.19 0.24
119 INT52585 RPL35AP35 Positive_regulation of Positive_regulation of Ca2 1 0.00 0.34 0.24
120 INT130689 CA2 Positive_regulation of ATF4 1 0.13 0.59 0.24
121 INT330797 Positive_regulation of Accn2 Positive_regulation of Ca2 1 0.03 0 0.23
122 INT268946 Ros1 Regulation of Gene_expression of Ca2 1 0.00 0.18 0.23
123 INT191480 Htr3a Positive_regulation of Ca2 1 0.02 0.12 0.23
124 INT309751 Binding of CA2 and TRPV4 1 0.08 0 0.23
125 INT251452 Binding of Car1 and Kcnc1 1 0.11 0 0.22
126 INT265360 Binding of Car2 and Daf2 1 0.18 0.09 0.22
127 INT89238 Positive_regulation of RUNX1 Positive_regulation of Positive_regulation of CA2 1 0.01 0 0.22
128 INT248173 Car2 Positive_regulation of GRIN1 1 0.08 0 0.22
129 INT353691 Slc8a1 Positive_regulation of Ca2 1 0.18 0.45 0.22
130 INT330546 Positive_regulation of Trpm8 Positive_regulation of Positive_regulation of Ca2 1 0.13 0.67 0.22
131 INT264778 Binding of CA2 and Gabbr1 1 0.02 0 0.21
132 INT80620 CA2 Regulation of KCNIP3 1 0.11 0.08 0.21
133 INT261048 CHR Positive_regulation of CA2 1 0.03 0.21 0.21
134 INT190745 Adcyap1 Regulation of Car2 1 0.08 0 0.21
135 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2
136 INT290855 PPR Regulation of Ca2 1 0.01 0.45 0.2
137 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2
138 INT350348 Binding of Car1 and Chrm1 1 0.09 0 0.2
139 INT80927 Acot1 Positive_regulation of Car2 1 0.31 0 0.2
140 INT212921 Positive_regulation of Binding of Car2 and Tg(CAG-EGFP)D4Nagy 1 0.12 0.22 0.19
141 INT308646 Car2 Regulation of Gene_expression of Ins1 1 0.00 0 0.19
142 INT212920 Binding of Car2 and Tg(CAG-EGFP)D4Nagy 1 0.09 0.22 0.19
143 INT291797 Binding of CA2 and Positive_regulation of MYLK 1 0.15 0.33 0.19
144 INT354223 Binding of Car2 and Igfbp7 1 0.02 0.4 0.19
145 INT330795 Positive_regulation of Accn2 Positive_regulation of Positive_regulation of Ca2 1 0.03 0 0.18
146 INT207640 Binding of Car2 and Nrgn 1 0.04 0 0.18
147 INT290858 Positive_regulation of Ca2 Regulation of PPR 1 0.01 0.5 0.18
148 INT285183 Cd2 Regulation of Ca2 1 0.30 0.23 0.18
149 INT290856 Ca2 Regulation of PPR 1 0.01 0.5 0.18
150 INT328923 Car2 Positive_regulation of Prkca 1 0.00 0 0.18
151 INT11790 CA2 Regulation of Localization of PRL 1 0.23 0 0.18
152 INT69949 Car2 Positive_regulation of MTAP 1 0.02 0.41 0.18
153 INT334769 Ednra Positive_regulation of Car2 1 0.02 0.49 0.18
154 INT351759 Gria2 Regulation of Car2 1 0.07 0.4 0.17
155 INT216487 Ca2 Negative_regulation of Kcnma1 1 0.00 0.1 0.17
156 INT264277 Binding of Car2 and P2rx1 1 0.10 0 0.16
157 INT190744 Adcyap1 Positive_regulation of Car2 1 0.10 0.08 0.16
158 INT40845 Ca2 Positive_regulation of Pla2g1b 1 0.16 0 0.16
159 INT5737 Hk1 Positive_regulation of Ca2 1 0.06 0.16 0.16
160 INT345176 Lpar1 Positive_regulation of Gene_expression of Car2 1 0.03 0.11 0.16
161 INT235085 NOS1 Positive_regulation of CA2 1 0.07 0.18 0.15
162 INT216601 Itpr3 Positive_regulation of Localization of Ca2 1 0.00 0.05 0.15
163 INT77121 WDTC1 Positive_regulation of Localization of CA2 1 0.10 0.39 0.15
164 INT276060 Pde1b Regulation of Car2 1 0.30 0 0.15
165 INT342150 Ca2 Positive_regulation of Localization of Gast 1 0.03 0.27 0.14
166 INT182937 KCNIP3 Regulation of Binding of CA2 1 0.05 0.2 0.14
167 INT283947 Positive_regulation of Car1 Positive_regulation of Ptgfrn 1 0.01 0 0.14
168 INT334765 Ednra Positive_regulation of Positive_regulation of Car2 1 0.02 0.24 0.14
169 INT180447 Binding of Rhoa and Car2 1 0.17 0.56 0.13
170 INT182958 Binding of CA2 and CREB1 1 0.04 0.25 0.13
171 INT323149 Positive_regulation of DBT Regulation of CA2 1 0.01 0 0.13
172 INT309743 Binding of CA2 and CALM3 1 0.04 0 0.13
173 INT216787 Svs4 Positive_regulation of Ca2 1 0.06 0 0.13
174 INT48595 NT5C3 Positive_regulation of CA2 1 0.01 0 0.13
175 INT216791 Regulation of Svs4 Positive_regulation of Ca2 1 0.02 0 0.13
176 INT329473 SLC7A7 Regulation of Ca2 1 0.04 0.1 0.13
177 INT323151 DBT Regulation of CA2 1 0.01 0 0.13
178 INT216486 Pck1 Regulation of Gene_expression of Ca2 1 0.05 0.19 0.13
179 INT335300 SLC15A4 Regulation of CA2 1 0.00 0.19 0.12
180 INT190743 Adcyap1 Regulation of Gene_expression of Car2 1 0.10 0.06 0.12
181 INT182951 Binding of CA2 and Positive_regulation of Localization of KCNIP3 1 0.09 0.17 0.12
182 INT350736 PRKDC Negative_regulation of CA2 1 0.02 0.16 0.11
183 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1
184 INT50533 Binding of ADRB3 and Positive_regulation of Gene_expression of CA3 1 0.11 0.61 0.1
185 INT341880 Oxt Positive_regulation of Ca2 1 0.09 0 0.1
186 INT354215 Binding of Car2 and Accn3 1 0.03 0.21 0.1
187 INT263729 Grin2b Positive_regulation of Gene_expression of Car1 1 0.20 0 0.1
188 INT273236 Cdk5 Positive_regulation of Car2 1 0.13 0.45 0.1
189 INT254456 Negative_regulation of Binding of Calm2 and Ca2 1 0.03 0 0.1
190 INT201748 Car2 Positive_regulation of Cdk5r1 1 0.00 0.67 0.09
191 INT180449 Rhoa Regulation of Positive_regulation of Car2 1 0.13 0 0.09
192 INT341877 Oxtr Regulation of Ca2 1 0.08 0 0.09
193 INT201751 Car2 Positive_regulation of Cdk5 1 0.00 0.67 0.09
194 INT276039 Positive_regulation of Car2 Positive_regulation of Positive_regulation of Rpa1 1 0.04 0 0.09
195 INT29838 Gnrh1 Positive_regulation of Localization of Ca2 1 0.17 0 0.09
196 INT286568 Car2 Positive_regulation of Positive_regulation of Pkd1 1 0.03 0.16 0.09
197 INT241040 Slc8a1 Negative_regulation of Gene_expression of Ca2 1 0.15 1.35 0.09
198 INT215007 Car2 Regulation of Gene_expression of Trpv6 1 0.07 0.25 0.09
199 INT190746 Positive_regulation of Gria2 Positive_regulation of Car2 1 0.00 0.13 0.09
200 INT309738 CALM3 Positive_regulation of CA2 1 0.04 0 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for carbonate dehydratase activity. They are ordered first by their pain relevance and then by number of times they were reported in carbonate dehydratase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64
2 INT4822 Localization of Ca2 417 0.80 99.57 96.45
3 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35
4 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71
5 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01
6 INT1032 Regulation of Ca2 202 0.52 54.91 53.03
7 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76
8 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97
9 INT17561 Localization of Car2 303 0.79 60.95 44.52
10 INT12029 Gene_expression of Car1 143 0.67 29.69 36.39
11 INT5489 Localization of CA2 172 0.80 39.46 33.56
12 INT111081 Gene_expression of CA1 19 0.75 51.09 26.64
13 INT13145 Positive_regulation of Car1 60 0.70 16.32 23.23
14 INT17962 Regulation of Car2 124 0.41 33.98 22.71
15 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86
16 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4
17 INT12031 Negative_regulation of Car1 44 0.59 20.46 19.36
18 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72
19 INT197375 Gene_expression of Car1 84 0.65 16.46 16.45
20 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07
21 INT19799 Binding of Ca2 71 0.48 13.69 12.92
22 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35
23 INT119400 Phosphorylation of Car2 19 0.52 8.47 11.63
24 INT25170 Positive_regulation of Localization of Car2 78 0.67 15.25 11.24
25 INT311552 Positive_regulation of Gene_expression of CA1 3 0.67 21.83 11.2
26 INT3535 Regulation of CA2 61 0.32 16.48 10.8
27 INT29967 Positive_regulation of Positive_regulation of Car2 40 0.40 8.03 10.13
28 INT33094 Regulation of Localization of Ca2 28 0.38 8.65 9.96
29 INT14881 Gene_expression of Car3 49 0.73 14.89 9.94
30 INT23535 Positive_regulation of Localization of CA2 41 0.41 13.52 9.43
31 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35
32 INT1129 Binding of Car2 69 0.35 14.01 9.2
33 INT170504 Positive_regulation of Gene_expression of Car2 60 0.41 19.1 8.45
34 INT12028 Regulation of Car1 28 0.43 9.01 7.84
35 INT202868 Positive_regulation of Car1 30 0.44 15.48 7.42
36 INT12032 Negative_regulation of Gene_expression of Car1 16 0.34 7.23 7.03
37 INT19366 Negative_regulation of Localization of Ca2 33 0.50 6.51 6.61
38 INT195145 Positive_regulation of Gene_expression of CA2 25 0.37 7.2 6.59
39 INT96164 Positive_regulation of CA1 8 0.67 10.99 6.23
40 INT245587 Regulation of Car1 13 0.27 4.68 5.72
41 INT5490 Binding of CA2 52 0.36 9.73 5.53
42 INT149739 Regulation of Gene_expression of Ca2 25 0.38 7.22 5.53
43 INT170516 Negative_regulation of Gene_expression of Car2 35 0.35 9.4 5.48
44 INT22160 Negative_regulation of Positive_regulation of Car2 18 0.38 4.94 5.45
45 INT12030 Positive_regulation of Gene_expression of Car1 15 0.50 3.98 5.27
46 INT74051 Negative_regulation of Localization of Car2 27 0.38 9.58 5.1
47 INT6983 Negative_regulation of Positive_regulation of Ca2 18 0.41 4.29 5.03
48 INT128353 Negative_regulation of Car3 16 0.37 4.93 4.61
49 INT76467 Regulation of Gene_expression of Car2 41 0.37 12.88 4.21
50 INT159119 Negative_regulation of Car1 17 0.37 6.6 4.01
51 INT2073 Regulation of CA1 5 0.26 4.9 3.86
52 INT14880 Positive_regulation of Car3 14 0.65 9.19 3.73
53 INT41541 Regulation of Gene_expression of Car1 9 0.41 3.82 3.52
54 INT76468 Regulation of Positive_regulation of Car2 13 0.29 4.54 3.46
55 INT218814 Negative_regulation of Gene_expression of Car1 12 0.24 3.95 3.24
56 INT15549 Regulation of Positive_regulation of Ca2 11 0.38 2.55 2.92
57 INT91520 Negative_regulation of Positive_regulation of CA2 7 0.30 0.99 2.92
58 INT50535 Gene_expression of CA3 25 0.51 9.25 2.89
59 INT82841 Localization of Car1 11 0.68 3.91 2.84
60 INT2042 Phosphorylation of Ca2 21 0.55 1.54 2.81
61 INT14883 Regulation of Car3 8 0.58 5.57 2.75
62 INT70253 Negative_regulation of Gene_expression of Ca2 29 0.49 16.31 2.69
63 INT245671 Positive_regulation of Gene_expression of Car1 15 0.28 4.31 2.67
64 INT196870 Positive_regulation of Phosphorylation of Car2 6 0.26 3.43 2.63
65 INT83681 Positive_regulation of CA3 3 0.49 0.06 2.6
66 INT80319 Negative_regulation of Negative_regulation of Car1 3 0.59 2 2.58
67 INT93562 Negative_regulation of Localization of CA2 15 0.59 1.87 2.51
68 INT31550 Binding of Car1 10 0.30 1.54 2.24
69 INT72743 Positive_regulation of Negative_regulation of Ca2 4 0.49 1.41 2.11
70 INT149066 Regulation of CA3 5 0.44 0.89 2.02
71 INT245669 Negative_regulation of Gene_expression of Car3 7 0.37 1.87 1.9
72 INT24283 Regulation of Positive_regulation of CA2 8 0.30 3.06 1.74
73 INT64807 Positive_regulation of Positive_regulation of CA2 10 0.41 1.21 1.7
74 INT35325 Regulation of Localization of CA2 10 0.32 1.13 1.69
75 INT2074 Negative_regulation of CA1 6 0.58 4.44 1.68
76 INT146566 Transcription of Car2 8 0.56 1.51 1.6
77 INT291968 Localization of CA1 5 0.73 4.21 1.6
78 INT19798 Positive_regulation of Binding of Ca2 2 0.41 1.37 1.54
79 INT119936 Transcription of Ca2 13 0.59 1.71 1.47
80 INT68772 Regulation of Negative_regulation of Car1 2 0.44 0.17 1.45
81 INT261406 Positive_regulation of Positive_regulation of Car1 1 0.27 1.09 1.34
82 INT184750 Positive_regulation of Car9 3 0.08 6.38 1.27
83 INT60281 Negative_regulation of Negative_regulation of Car2 4 0.36 1.88 1.26
84 INT47278 Positive_regulation of Positive_regulation of Car1 7 0.45 1.88 1.24
85 INT199386 Negative_regulation of Phosphorylation of Car2 1 0.16 1.37 1.14
86 INT49536 Regulation of Regulation of Ca2 6 0.38 3.89 1.13
87 INT23847 Phosphorylation of CA2 8 0.61 0.67 1.12
88 INT104913 Regulation of Positive_regulation of Car1 2 0.44 0 1.1
89 INT170511 Regulation of Localization of Car2 11 0.21 2.18 1.09
90 INT238532 Negative_regulation of Binding of Car2 4 0.29 0.61 1.07
91 INT70327 Regulation of Gene_expression of CA2 11 0.28 1.92 1.05
92 INT70323 Negative_regulation of Gene_expression of CA2 13 0.41 6.55 0.97
93 INT47757 Transcription of CA2 5 0.67 1.16 0.97
94 INT197365 Localization of Car1 7 0.73 1.11 0.94
95 INT32693 Positive_regulation of Gene_expression of Car3 6 0.42 2.7 0.89
96 INT132690 Negative_regulation of Positive_regulation of CA1 1 0.40 1.26 0.87
97 INT146568 Positive_regulation of Transcription of Car2 1 0.31 1.39 0.78
98 INT247935 Transcription of Car1 4 0.44 1.43 0.76
99 INT212006 Transcription of CA1 2 0.66 1.14 0.76
100 INT287841 Positive_regulation of Phosphorylation of Ca2 2 0.18 0.58 0.75
101 INT119933 Transcription of Car1 4 0.52 1.06 0.74
102 INT281853 Regulation of Regulation of Car1 1 0.13 0.27 0.74
103 INT34496 Negative_regulation of Binding of Car1 3 0.37 0.61 0.7
104 INT197371 Regulation of Gene_expression of Car3 2 0.39 0.64 0.65
105 INT353145 Negative_regulation of Gene_expression of CA1 1 0.42 1.01 0.65
106 INT68403 Positive_regulation of Negative_regulation of Car1 1 0.41 0.33 0.59
107 INT17964 Negative_regulation of Regulation of Car2 3 0.36 0.58 0.58
108 INT23095 Negative_regulation of Regulation of Ca2 2 0.36 0.34 0.56
109 INT72294 Binding of CA3 3 0.32 0.54 0.55
110 INT264594 Negative_regulation of Binding of CA2 4 0.20 1.1 0.52
111 INT248783 Positive_regulation of Protein_catabolism of CA2 1 0.13 0 0.52
112 INT248784 Protein_catabolism of CA2 1 0.22 0 0.52
113 INT32137 Regulation of Negative_regulation of Ca2 7 0.36 2.17 0.49
114 INT324578 Positive_regulation of Regulation of Car2 1 0.20 0.23 0.49
115 INT197369 Regulation of Gene_expression of Car1 4 0.24 0.25 0.47
116 INT122156 Binding of CA1 3 0.47 1.52 0.44
117 INT230267 Negative_regulation of CA3 3 0.28 1.4 0.44
118 INT237470 Negative_regulation of Localization of Car1 1 0.32 0.26 0.43
119 INT348865 Regulation of Transcription of CA2 1 0.21 0.69 0.43
120 INT47758 Positive_regulation of Transcription of CA2 3 0.49 0.54 0.42
121 INT249246 Positive_regulation of Phosphorylation of CA2 2 0.26 0.06 0.42
122 INT250447 Positive_regulation of Binding of Car2 3 0.11 0.36 0.39
123 INT135677 Protein_catabolism of Car1 1 0.74 0.41 0.39
124 INT2043 Negative_regulation of Phosphorylation of Ca2 2 0.38 0 0.38
125 INT72295 Regulation of Binding of CA3 1 0.39 0.1 0.38
126 INT349132 Positive_regulation of Localization of Car1 1 0.29 0.1 0.37
127 INT276021 Regulation of Transcription of Car2 2 0.30 0.08 0.36
128 INT235342 Localization of Car3 2 0.41 0.43 0.33
129 INT249273 Regulation of Regulation of CA2 3 0.23 0.26 0.31
130 INT257799 Phosphorylation of Car1 2 0.43 0.19 0.3
131 INT149737 Positive_regulation of Regulation of Ca2 3 0.58 1 0.27
132 INT217386 Negative_regulation of Positive_regulation of Car1 2 0.18 1.67 0.25
133 INT84919 Localization of CA3 1 0.59 0.4 0.25
134 INT343362 Positive_regulation of Regulation of Car1 1 0.35 0 0.25
135 INT32301 Regulation of Binding of Ca2 5 0.38 1.07 0.24
136 INT269040 Regulation of Negative_regulation of Car1 1 0.28 0.3 0.24
137 INT349970 Regulation of Localization of Car1 1 0.41 0 0.23
138 INT269032 Binding of Car1 2 0.20 0.67 0.22
139 INT201150 Protein_catabolism of Ca2 4 0.75 2.63 0.21
140 INT235354 Regulation of Localization of Car3 1 0.19 0.12 0.21
141 INT185187 Regulation of Car9 1 0.00 0.96 0.21
142 INT273219 Regulation of Positive_regulation of Car1 1 0.22 1.1 0.2
143 INT235620 Regulation of Transcription of Ca2 1 0.38 0 0.2
144 INT122155 Negative_regulation of Binding of CA1 1 0.42 0.6 0.2
145 INT240712 Negative_regulation of Negative_regulation of Ca2 4 0.36 0.38 0.19
146 INT318561 Negative_regulation of Phosphorylation of CA2 1 0.02 0 0.18
147 INT81942 Regulation of Regulation of Car2 5 0.29 0.43 0.16
148 INT187326 Regulation of Regulation of Car1 1 0.15 0 0.16
149 INT311548 Positive_regulation of Positive_regulation of CA1 1 0.30 0.75 0.16
150 INT184749 Gene_expression of Car9 9 0.31 9.45 0.14
151 INT243530 Positive_regulation of Gene_expression of CA3 1 0.10 0.47 0.14
152 INT195698 Positive_regulation of CA13 1 0.22 1.75 0.13
153 INT330082 Negative_regulation of Positive_regulation of Car1 1 0.17 0.17 0.13
154 INT311119 Positive_regulation of Localization of Car1 1 0.28 0.81 0.13
155 INT263871 Negative_regulation of Car9 1 0.07 0.54 0.12
156 INT257800 Binding of Car3 1 0.28 0.19 0.12
157 INT195690 Gene_expression of CA13 1 0.21 1.64 0.11
158 INT41962 Negative_regulation of Binding of Ca2 2 0.37 0.18 0.1
159 INT216809 Positive_regulation of Transcription of Ca2 2 0.40 0.08 0.09
160 INT346816 Positive_regulation of Regulation of Car1 1 0.20 0.27 0.09
161 INT249242 Positive_regulation of Negative_regulation of CA2 1 0.26 0.34 0.09
162 INT346815 Regulation of Transcription of Car1 1 0.18 0.27 0.09
163 INT249292 Negative_regulation of Negative_regulation of CA2 1 0.22 0 0.08
164 INT170552 Regulation of Negative_regulation of Car2 3 0.39 1.97 0.07
165 INT346812 Negative_regulation of Phosphorylation of Car1 1 0.14 0.19 0.06
166 INT346810 Positive_regulation of Phosphorylation of Car1 1 0.17 0.19 0.06
167 INT325560 Positive_regulation of Negative_regulation of Car2 2 0.25 0 0.05
168 INT266202 Gene_expression of Car8 1 0.74 1 0.05
169 INT195692 Negative_regulation of CA13 1 0.18 2.18 0.05
170 INT195689 Protein_catabolism of CA13 1 0.20 1.06 0.04
171 INT183004 Positive_regulation of Binding of CA2 1 0.10 0.07 0.04
172 INT234077 Regulation of Localization of Car1 1 0.23 0 0.03
173 INT287851 Regulation of Phosphorylation of Ca2 1 0.10 0.19 0.03
174 INT307842 Positive_regulation of Localization of Car9 1 0.26 1.04 0
175 INT249272 Regulation of Negative_regulation of CA2 1 0.14 0 0
176 INT266211 Positive_regulation of Car8 1 0.48 0.16 0
177 INT307843 Localization of Car9 1 0.39 1.04 0
178 INT195694 Positive_regulation of Gene_expression of CA13 1 0.16 0.6 0
179 INT287400 Negative_regulation of Transcription of Ca2 1 0.33 0 0
180 INT195693 Regulation of CA13 1 0.14 1.15 0
181 INT195688 Positive_regulation of Positive_regulation of CA13 1 0.22 0.27 0
182 INT276002 Regulation of Binding of Car2 1 0.35 0 0
183 INT195691 Phosphorylation of CA13 1 0.17 0.85 0
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