GO:0004091

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Name carboxylesterase activity
Categary Function
Go Slim No
Go Link GO:0004091
Unique Molecular Interactions 190
Total Molecular Interactions 254
Total Single Events 5065
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for carboxylesterase activity. They are ordered first by their pain relevance and then by number of times they were reported for carboxylesterase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT17300 Prss12 Positive_regulation of Localization of Acot1 4 0.11 0 3.28
2 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
3 INT17299 Prss12 Regulation of Localization of Acot1 3 0.05 0 2.07
4 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
5 INT30743 Cck Regulation of Localization of Acot1 1 0.02 0 1.64
6 INT18592 Sst Regulation of Localization of Acot1 2 0.22 0 1.61
7 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
8 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
9 INT45891 Tyms Positive_regulation of Localization of Acot1 1 0.02 0 1.23
10 INT310069 Negative_regulation of Pain1 Positive_regulation of Mgll 1 0.02 1.32 1.23
11 INT310067 Pain1 Positive_regulation of Mgll 1 0.02 1.29 1.21
12 INT62018 CSF2 Regulation of ACOT1 1 0.12 0.47 1.21
13 INT18596 Fdft1 Regulation of Localization of Acot1 1 0.06 0 1.14
14 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
15 INT285659 Binding of Faah and Mgll 1 0.15 0.99 1.11
16 INT18594 Binding of Fdft1 and Positive_regulation of Localization of Acot1 1 0.11 0 1.11
17 INT106345 Igf1 Regulation of Localization of Acot1 1 0.06 0 1.02
18 INT62017 ELANE Positive_regulation of Localization of ACOT1 1 0.05 0.35 0.98
19 INT18595 Fdft1 Positive_regulation of Localization of Acot1 1 0.08 0 0.96
20 INT18597 Sst Positive_regulation of Localization of Acot1 1 0.29 0 0.96
21 INT154259 Nts Positive_regulation of Acot1 1 0.04 0 0.91
22 INT251704 Ache Regulation of Gene_expression of Acot1 1 0.08 1.68 0.87
23 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85
24 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84
25 INT113250 Olr1259 Negative_regulation of Ache 1 0.01 0.38 0.83
26 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
27 INT128739 Penk Negative_regulation of Acot1 1 0.19 0 0.77
28 INT46246 Tpsg1 Regulation of Ache 1 0.15 0.06 0.76
29 INT46247 Tpsg1 Regulation of Binding of Ache 1 0.15 0.06 0.76
30 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
31 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
32 INT164713 Binding of Avp and Positive_regulation of Localization of Acot1 1 0.32 0.43 0.69
33 INT164715 Avp Positive_regulation of Localization of Acot1 1 0.28 0.43 0.69
34 INT172698 Ugt1a6 Negative_regulation of Localization of Acot1 1 0.01 0 0.68
35 INT56669 Nts Regulation of Localization of Acot1 2 0.12 0 0.65
36 INT164721 Binding of NT5C and Acot1 1 0.04 0.45 0.65
37 INT164714 Binding of Avp and Acot1 1 0.26 0.45 0.64
38 INT190525 Acot1 Positive_regulation of Localization of S100a8 1 0.00 0.86 0.63
39 INT190526 Acot1 Positive_regulation of Il1 1 0.01 0.87 0.63
40 INT26648 Binding of CEL and HP 1 0.04 0 0.58
41 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
42 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48
43 INT28032 TNIP3 Negative_regulation of Acot1 1 0.00 0 0.47
44 INT109780 WAS Regulation of Localization of Acot1 1 0.01 0.26 0.46
45 INT285661 Binding of Mgll and FAAH2 1 0.05 0.23 0.45
46 INT53649 Acot1 Positive_regulation of Calca 1 0.25 0 0.44
47 INT87009 Acot1 Negative_regulation of Hc3 1 0.19 0.34 0.43
48 INT5531 Binding of Acot1 and Chrna2 1 0.12 0 0.42
49 INT171185 Binding of NEUROD1 and ACOT1 1 0.01 0.37 0.42
50 INT171186 Binding of PPFIA4 and ACOT1 1 0.00 0.37 0.42
51 INT171183 Binding of BHLHE23 and ACOT1 1 0.01 0.36 0.42
52 INT69109 Acot1 Regulation of Gene_expression of Serpine2 1 0.04 0 0.4
53 INT356199 GOPC Positive_regulation of Acot7 1 0.04 0.33 0.4
54 INT180442 Acot1 Positive_regulation of Rhoa 1 0.08 1.03 0.38
55 INT49123 Negative_regulation of Nka1 Positive_regulation of Acot1 1 0.06 0 0.38
56 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38
57 INT49122 Nka1 Positive_regulation of Acot1 1 0.07 0 0.38
58 INT340850 Binding of IGHE and Baat 1 0.07 0.27 0.37
59 INT87769 Binding of Acot1 and Treh 1 0.00 0 0.35
60 INT51630 Binding of ACHE and OPRM1 1 0.11 0 0.33
61 INT51628 Binding of ACHE and DRD3 1 0.15 0 0.33
62 INT31754 Prl Negative_regulation of Bche 1 0.35 0 0.32
63 INT31753 Prl Regulation of Bche 1 0.37 0 0.32
64 INT343366 Acsf2 Negative_regulation of Acot1 1 0.05 0 0.31
65 INT17162 Binding of CEL and Lhb 1 0.06 0.38 0.3
66 INT58898 Adcyap1 Regulation of Localization of Acot1 1 0.17 0 0.28
67 INT58899 Vip Regulation of Localization of Acot1 1 0.17 0 0.28
68 INT272174 Acot1 Regulation of Ca2 1 0.01 0 0.26
69 INT40964 Binding of Eef1a1 and Positive_regulation of Localization of Acot1 1 0.08 0 0.26
70 INT160225 Acot1 Negative_regulation of Ache 1 0.28 2.18 0.25
71 INT23626 Ache Regulation of Mir343 1 0.17 0 0.24
72 INT97868 Binding of Chrna2 and Regulation of Acot1 1 0.09 0 0.23
73 INT124383 ACOT1 Positive_regulation of MME 1 0.01 0.17 0.22
74 INT106993 CEL Positive_regulation of NR1I2 1 0.39 0.39 0.22
75 INT167486 Positive_regulation of Binding of CD63 and ACOT1 1 0.01 0 0.21
76 INT167485 Binding of CD63 and ACOT1 1 0.00 0 0.21
77 INT80927 Acot1 Positive_regulation of Car2 1 0.31 0 0.2
78 INT180441 Acot1 Positive_regulation of Gopc 1 0.03 0.43 0.19
79 INT180435 Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
80 INT180444 Positive_regulation of Acot1 Positive_regulation of Rhoa 1 0.08 0.43 0.19
81 INT60417 Chrm1 Regulation of Localization of Acot1 1 0.13 0 0.19
82 INT180437 Positive_regulation of Acot1 Positive_regulation of Positive_regulation of Rhoa 1 0.08 0.43 0.19
83 INT159720 Slc5a7 Regulation of Gene_expression of Acot1 1 0.12 0 0.19
84 INT180440 Positive_regulation of Acot1 Positive_regulation of Gopc 1 0.03 0.43 0.19
85 INT251665 LRP5 Negative_regulation of Ache 1 0.31 0.39 0.19
86 INT159722 Slc5a7 Positive_regulation of Gene_expression of Acot1 1 0.12 0 0.19
87 INT159721 Hc3 Negative_regulation of Gene_expression of Acot1 1 0.04 0 0.19
88 INT49057 Positive_regulation of CEL Positive_regulation of Localization of LTC4S 1 0.41 0.28 0.18
89 INT264101 Binding of CYP2D6 and Bche 1 0.07 0.33 0.18
90 INT60348 Trh Positive_regulation of Positive_regulation of Acot1 1 0.29 0.44 0.17
91 INT70090 TGM1 Positive_regulation of Binding of Ache 1 0.03 0.59 0.15
92 INT10197 Dclk2 Positive_regulation of Localization of Acot1 1 0.03 0.26 0.15
93 INT10198 Dclk2 Regulation of Localization of Acot1 1 0.02 0.26 0.15
94 INT231838 Pcdh8 Regulation of Cel 1 0.00 0.39 0.15
95 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14
96 INT231846 Pcdh8 Negative_regulation of Positive_regulation of Cel 1 0.00 0.91 0.14
97 INT141224 Ache Regulation of Acot1 1 0.09 0.29 0.14
98 INT27393 Tha1 Negative_regulation of Ache 1 0.15 0.24 0.14
99 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14
100 INT75791 Positive_regulation of Htr3a Regulation of Acot1 1 0.23 0.12 0.14
101 INT42772 Penk Negative_regulation of Ache 1 0.06 0 0.14
102 INT110107 Acot1 Positive_regulation of Localization of Prkce 1 0.11 0 0.12
103 INT210549 Binding of BCHE and Ache 1 0.01 0.82 0.12
104 INT104327 Fen1 Negative_regulation of Baat 1 0.31 0.75 0.12
105 INT104325 Regulation of Fen1 Negative_regulation of Baat 1 0.19 0.75 0.12
106 INT235385 INCENP Negative_regulation of Bche 1 0.01 0.19 0.11
107 INT123101 Binding of APP and Ache 1 0.07 0.32 0.11
108 INT34497 Binding of Oprl1 and Ache 1 0.40 0 0.1
109 INT92671 Binding of CEL and HLA-B 1 0.38 0.19 0.1
110 INT141223 Bche Regulation of Gene_expression of Acot1 1 0.09 0 0.1
111 INT141225 Bche Regulation of Acot1 1 0.09 0 0.1
112 INT246535 Binding of Cel and Mag 1 0.01 7.26 0.1
113 INT32030 Binding of CEL and ERLEC1 1 0.08 0.42 0.1
114 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09
115 INT5529 Acot1 Positive_regulation of Chrna2 1 0.17 0 0.09
116 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08
117 INT227303 Zbp1 Regulation of Transcription of Baat 1 0.09 1.43 0.08
118 INT251712 Fig4 Regulation of Ache 1 0.02 0.23 0.08
119 INT251703 Fig4 Regulation of Localization of Ache 1 0.07 0.23 0.08
120 INT5530 Positive_regulation of Binding of Acot1 and Chrna2 1 0.15 0 0.07
121 INT290158 Binding of Ache and Atp6v1e1 1 0.19 0 0.07
122 INT245988 C1QL3 Negative_regulation of Gene_expression of CES1 1 0.02 0.17 0.07
123 INT231834 Trip12 Positive_regulation of Positive_regulation of Cel 1 0.00 0.75 0.05
124 INT133047 TNF Positive_regulation of Gene_expression of CEL 1 0.47 0.61 0.05
125 INT46677 H2-Q4 Negative_regulation of Bche 1 0.10 0.26 0.05
126 INT177350 Binding of CEL and PLA2G2A 1 0.06 0.08 0.04
127 INT323392 SERPINH1 Negative_regulation of BCHE 1 0.02 0.52 0.04
128 INT291174 Rpa1 Positive_regulation of Baat 1 0.03 0.63 0.04
129 INT266452 Binding of Acot1 and GOPC 1 0.02 1.23 0.04
130 INT266454 Binding of HEY1 and Acot1 1 0.00 1.19 0.04
131 INT266039 Binding of Acot1 and Amh-rs5 1 0.00 0.13 0.04
132 INT330875 PLDN Negative_regulation of Gene_expression of Ache 1 0.01 0.85 0.03
133 INT251701 Bche Regulation of Gene_expression of Acot1 1 0.03 0.25 0.03
134 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
135 INT177352 Binding of CEL and PTN 1 0.01 0 0.03
136 INT323395 Binding of BCHE and SERPINH1 1 0.02 0.74 0.03
137 INT46678 H2-Q4 Negative_regulation of Ache 1 0.10 0.12 0
138 INT227366 Binding of CES1 and PTER 1 0.24 0 0
139 INT104540 FOXG1 Regulation of Lipc 1 0.02 0 0
140 INT227365 Binding of CES2 and PTER 1 0.25 0 0
141 INT49894 Acot1 Positive_regulation of Rrsv 1 0.10 0 0
142 INT307602 Binding of ACHE and LRP5 1 0.01 0.17 0
143 INT186689 Binding of ACHE and Edn1 1 0.28 0 0
144 INT239325 Eef1a2 Negative_regulation of Lipc 1 0.11 0.84 0
145 INT227367 CES2 Negative_regulation of Localization of KDELC1 1 0.03 0 0
146 INT190492 Br Regulation of Ache 1 0.30 0.55 0
147 INT326162 Binding of ABHD2 and Scrib 1 0.00 1.07 0
148 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
149 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0
150 INT266453 SNRNP70 Regulation of Acot1 1 0.00 0.53 0
151 INT215764 Dio1 Regulation of Ces1c 1 0.00 0.05 0
152 INT215685 Slc3a1 Regulation of Ces1c 1 0.00 0.05 0
153 INT268013 Binding of Nos3 and Acot1 1 0.02 1.48 0
154 INT104328 Fen1 Positive_regulation of Baat 1 0.33 0.63 0
155 INT330876 PLDN Negative_regulation of Ache 1 0.01 0.45 0
156 INT227368 Binding of CES1 and CES2 1 0.36 0 0
157 INT44885 Binding of CEL and MET 1 0.39 0.15 0
158 INT104326 Regulation of Fen1 Positive_regulation of Baat 1 0.19 0.63 0
159 INT262716 Binding of ACHE and BCHE 1 0.09 0.11 0
160 INT181835 Binding of Baat and Ppara 1 0.09 0.31 0
161 INT246536 Mag Regulation of Gene_expression of Cel 1 0.01 1.28 0
162 INT291173 Ins1 Regulation of Baat 1 0.12 0.83 0
163 INT192087 Atr Regulation of Localization of Acot1 1 0.04 0 0
164 INT332898 Binding of Ahrr and Aadac 1 0.00 0.08 0
165 INT49893 Acot1 Positive_regulation of Nrf1 1 0.00 0 0
166 INT251702 Fig4 Regulation of Positive_regulation of Ache 1 0.07 0.42 0
167 INT180439 Rhoa Regulation of Gene_expression of Acot1 1 0.07 0.17 0
168 INT256486 Si Negative_regulation of Gene_expression of Ces1c 1 0.00 0.19 0
169 INT302586 Binding of Lipc and Apoa5 1 0.26 0.63 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for carboxylesterase activity. They are ordered first by their pain relevance and then by number of times they were reported in carboxylesterase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1352 Localization of Acot1 728 0.80 73.01 296.01
2 INT3766 Positive_regulation of Localization of Acot1 192 0.69 21.8 85.35
3 INT1353 Negative_regulation of Localization of Acot1 153 0.53 15.05 75.17
4 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
5 INT1316 Positive_regulation of Acot1 129 0.60 18.86 56.13
6 INT3188 Regulation of Localization of Acot1 84 0.59 8.94 38.56
7 INT1354 Negative_regulation of Acot1 87 0.43 15.01 36.44
8 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
9 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
10 INT4735 Gene_expression of Acot1 80 0.71 13.22 26.68
11 INT605 Regulation of Acot1 61 0.62 10.7 26.34
12 INT276 Regulation of Ache 83 0.62 16.75 25.99
13 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58
14 INT45437 Localization of Acot1 84 0.79 17.37 22.18
15 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51
16 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4
17 INT19071 Localization of Ache 66 0.81 5.1 16.27
18 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
19 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87
20 INT20721 Localization of ACOT1 47 0.80 11.37 10.95
21 INT3982 Gene_expression of Acot1 53 0.56 7.61 10.46
22 INT1252 Binding of Ache 46 0.48 9.94 10.25
23 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83
24 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
25 INT3983 Positive_regulation of Acot1 30 0.68 5.83 8.34
26 INT12757 Negative_regulation of Positive_regulation of Acot1 16 0.42 2.27 8.25
27 INT127 Positive_regulation of ACOT1 16 0.32 5.12 6.57
28 INT45101 Positive_regulation of Gene_expression of Acot1 13 0.40 2.2 6.55
29 INT169653 Negative_regulation of Mgll 6 0.42 3.75 6.16
30 INT13854 Positive_regulation of Positive_regulation of Acot1 13 0.50 1.78 6.03
31 INT35928 Positive_regulation of Baat 12 0.69 12.23 5.43
32 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
33 INT71418 Binding of CES1 42 0.40 29.78 5.01
34 INT23245 Positive_regulation of Gene_expression of CEL 19 0.69 14.81 4.92
35 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
36 INT27803 Regulation of ACOT1 16 0.38 5.94 4.64
37 INT14502 Gene_expression of BCHE 40 0.67 18.52 4.6
38 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
39 INT18995 Binding of CEL 23 0.47 14.46 4.5
40 INT45433 Positive_regulation of Localization of Acot1 18 0.45 1.9 4.32
41 INT147697 Gene_expression of ABHD2 8 0.78 8.15 4.3
42 INT3722 Negative_regulation of Acot1 19 0.42 4.88 4.21
43 INT11946 Transcription of Ache 18 0.69 2.62 4.13
44 INT3530 Regulation of BCHE 18 0.60 5.47 4.12
45 INT94132 Binding of ACOT1 7 0.13 2.62 4.04
46 INT5526 Binding of Acot1 13 0.30 0.67 4
47 INT4464 Localization of CEL 21 0.80 8.09 3.88
48 INT20455 Positive_regulation of Bche 15 0.59 7.22 3.7
49 INT8778 Regulation of Ache 17 0.62 3.7 3.57
50 INT168677 Negative_regulation of ACOT1 14 0.27 6.29 3.52
51 INT115227 Regulation of Localization of Acot1 12 0.60 0.15 3.51
52 INT41490 Regulation of Acot1 14 0.45 1.59 3.34
53 INT175442 Gene_expression of Cel 22 0.34 21.36 3.33
54 INT28009 Positive_regulation of Gene_expression of Ache 15 0.70 5.46 3.26
55 INT8777 Positive_regulation of Ache 25 0.68 7.77 3.18
56 INT27973 Gene_expression of ACOT1 31 0.65 15.7 3.15
57 INT53813 Positive_regulation of Cel 20 0.58 19.39 3.05
58 INT153616 Gene_expression of Mgll 5 0.50 2.72 3.03
59 INT22069 Positive_regulation of Localization of Ache 9 0.70 0.61 2.9
60 INT20722 Regulation of Localization of ACOT1 5 0.27 1.43 2.86
61 INT11892 Gene_expression of ACHE 10 0.68 1.32 2.63
62 INT20060 Protein_catabolism of Acot1 6 0.56 0.22 2.45
63 INT1864 Regulation of Bche 18 0.47 6.18 2.44
64 INT33134 Negative_regulation of Aadac 5 0.37 0.46 2.43
65 INT27338 Regulation of ACHE 6 0.62 1.25 2.38
66 INT70420 Positive_regulation of Localization of ACOT1 11 0.30 1.26 2.25
67 INT20720 Negative_regulation of Localization of ACOT1 6 0.35 2.66 2.25
68 INT14890 Localization of ACHE 5 0.80 0.47 2.21
69 INT22719 Negative_regulation of Negative_regulation of Acot1 5 0.43 0.77 2.2
70 INT2570 Negative_regulation of Gene_expression of Ache 13 0.43 2.88 2.18
71 INT52072 Negative_regulation of Ces1c 6 0.31 1.37 2.13
72 INT153611 Protein_catabolism of Mgll 3 0.86 1 2.09
73 INT42172 Negative_regulation of Gene_expression of Acot1 7 0.38 1.64 1.96
74 INT14503 Binding of BCHE 13 0.48 3.95 1.85
75 INT47628 Regulation of CEL 9 0.60 4.5 1.85
76 INT38201 Negative_regulation of Localization of Ache 8 0.59 2.35 1.82
77 INT158374 Negative_regulation of Aadac 13 0.07 7.19 1.76
78 INT38574 Binding of Ache 9 0.47 3.64 1.74
79 INT8757 Binding of ACHE 10 0.48 5.84 1.72
80 INT117024 Negative_regulation of Localization of Acot1 6 0.41 1.56 1.7
81 INT2847 Positive_regulation of Negative_regulation of Ache 8 0.49 1.09 1.65
82 INT14891 Positive_regulation of ACHE 10 0.70 5.37 1.64
83 INT159718 Negative_regulation of Gene_expression of Acot1 4 0.16 1.4 1.56
84 INT147696 Positive_regulation of Gene_expression of ABHD2 1 0.70 2.57 1.55
85 INT75694 Regulation of Gene_expression of CEL 9 0.60 6.08 1.53
86 INT19181 Gene_expression of Bche 35 0.68 16.93 1.52
87 INT56309 Positive_regulation of Baat 9 0.39 8.47 1.51
88 INT60220 Positive_regulation of Gene_expression of Acot1 6 0.38 0.52 1.49
89 INT71417 Binding of CES2 6 0.47 0.23 1.31
90 INT111473 Gene_expression of CES2 15 0.78 1.35 1.29
91 INT8476 Binding of Bche 10 0.37 4.38 1.29
92 INT88396 Positive_regulation of CES1 6 0.49 2.93 1.29
93 INT11415 Negative_regulation of Cel 5 0.38 5.67 1.29
94 INT62021 Negative_regulation of Positive_regulation of ACOT1 1 0.18 0.51 1.24
95 INT133112 Regulation of Baat 2 0.61 11.99 1.2
96 INT37849 Negative_regulation of Negative_regulation of Ache 3 0.43 0.8 1.19
97 INT29772 Positive_regulation of Positive_regulation of Ache 3 0.50 0.09 1.18
98 INT132987 Positive_regulation of Positive_regulation of Acot1 5 0.39 1.43 1.12
99 INT27366 Negative_regulation of Negative_regulation of Ache 4 0.43 0.29 1.12
100 INT11063 Negative_regulation of CES1 16 0.53 6.92 1.11
101 INT56310 Gene_expression of Baat 15 0.44 15.5 1.11
102 INT47027 Positive_regulation of BCHE 6 0.50 2.32 1.09
103 INT20061 Negative_regulation of Protein_catabolism of Acot1 2 0.36 0 1.08
104 INT22720 Regulation of Negative_regulation of Acot1 3 0.24 0.34 1.04
105 INT123577 Negative_regulation of Positive_regulation of Baat 2 0.58 1.78 1.02
106 INT66492 Negative_regulation of CES2 8 0.42 0.73 0.96
107 INT87765 Binding of Acot1 4 0.07 2.59 0.95
108 INT45082 Protein_catabolism of Acot1 4 0.20 1.15 0.92
109 INT112520 Negative_regulation of Regulation of Ache 2 0.28 1.02 0.87
110 INT66491 Regulation of CES2 2 0.45 1.51 0.86
111 INT19070 Regulation of Localization of Ache 5 0.62 0.39 0.84
112 INT48481 Negative_regulation of Binding of Ache 4 0.36 1.76 0.76
113 INT322101 Localization of Cel 2 0.29 1.11 0.76
114 INT11944 Positive_regulation of Transcription of Ache 3 0.48 1.68 0.75
115 INT46245 Regulation of Binding of Ache 1 0.25 0.06 0.75
116 INT227601 Gene_expression of Acot7 7 0.75 1.54 0.74
117 INT81622 Positive_regulation of Positive_regulation of CEL 4 0.49 3.94 0.73
118 INT60826 Negative_regulation of Positive_regulation of Ache 3 0.50 0.68 0.73
119 INT169651 Positive_regulation of Protein_catabolism of Mgll 1 0.49 0.07 0.72
120 INT76127 Transcription of CEL 5 0.71 2.02 0.7
121 INT175450 Positive_regulation of Gene_expression of Cel 4 0.25 2.69 0.68
122 INT165813 Gene_expression of CES1 31 0.76 6.08 0.66
123 INT169654 Positive_regulation of Mgll 2 0.49 0.26 0.66
124 INT4195 Gene_expression of Ces1c 7 0.44 2.88 0.65
125 INT17296 Regulation of Positive_regulation of Acot1 2 0.24 0.29 0.65
126 INT108328 Negative_regulation of Gene_expression of CEL 6 0.57 2.56 0.63
127 INT27417 Gene_expression of Aadac 1 0.04 0.43 0.63
128 INT146813 Positive_regulation of Ces1c 4 0.46 0.95 0.61
129 INT44696 Gene_expression of Baat 5 0.64 3.1 0.59
130 INT310648 Negative_regulation of Negative_regulation of BCHE 2 0.27 1.79 0.59
131 INT107422 Positive_regulation of Regulation of Acot1 1 0.37 0 0.59
132 INT183163 Positive_regulation of Positive_regulation of Cel 9 0.31 11.55 0.58
133 INT135044 Regulation of Gene_expression of Ache 2 0.31 0.85 0.58
134 INT45724 Positive_regulation of Lipc 2 0.08 0.84 0.58
135 INT169489 Positive_regulation of Localization of CEL 1 0.45 0.34 0.58
136 INT231823 Negative_regulation of Positive_regulation of Cel 2 0.17 2.34 0.56
137 INT356226 Positive_regulation of Transcription of Acot1 1 0.06 0.28 0.54
138 INT356223 Transcription of Acot1 1 0.07 0.28 0.54
139 INT22721 Regulation of Protein_catabolism of Acot1 2 0.23 0.17 0.53
140 INT144394 Protein_catabolism of ACHE 1 0.89 0.24 0.53
141 INT4387 Phosphorylation of Ache 3 0.79 1.15 0.5
142 INT79516 Positive_regulation of Gene_expression of Bche 3 0.50 1 0.47
143 INT340845 Regulation of Baat 1 0.08 0 0.47
144 INT323400 Localization of BCHE 1 0.66 1.87 0.46
145 INT53811 Regulation of Cel 4 0.23 2.1 0.43
146 INT39873 Negative_regulation of Gene_expression of Ache 2 0.59 1.56 0.43
147 INT166858 Positive_regulation of Protein_catabolism of Acot1 1 0.10 0 0.43
148 INT104324 Negative_regulation of Baat 4 0.38 9.79 0.42
149 INT166857 Negative_regulation of Protein_catabolism of Acot1 1 0.12 0 0.42
150 INT228731 Negative_regulation of Gene_expression of Cel 2 0.17 1.12 0.41
151 INT32052 Positive_regulation of Negative_regulation of Acot1 2 0.24 0.73 0.41
152 INT86052 Regulation of Transcription of Ache 1 0.12 0 0.41
153 INT86053 Positive_regulation of Binding of Ache 2 0.43 0 0.4
154 INT60601 Negative_regulation of Negative_regulation of CEL 1 0.41 0.34 0.4
155 INT144535 Localization of CES1 11 0.73 4.33 0.39
156 INT104323 Regulation of Positive_regulation of Baat 2 0.39 1.61 0.38
157 INT94218 Positive_regulation of Regulation of Ache 2 0.40 0 0.38
158 INT8776 Negative_regulation of Positive_regulation of Ache 2 0.43 1.17 0.36
159 INT45360 Negative_regulation of Binding of Bche 1 0.37 0.27 0.36
160 INT46533 Binding of Ces1c 9 0.12 0.18 0.34
161 INT271775 Positive_regulation of Gene_expression of Ache 3 0.69 5.16 0.34
162 INT135069 Regulation of Localization of CEL 1 0.44 0 0.34
163 INT47026 Positive_regulation of Gene_expression of BCHE 1 0.44 0.23 0.34
164 INT44695 Binding of Baat 1 0.26 0.67 0.32
165 INT352167 Negative_regulation of Positive_regulation of CEL 1 0.04 1.07 0.31
166 INT59862 Phosphorylation of CEL 2 0.70 0.53 0.3
167 INT128916 Regulation of CES1 5 0.40 2.95 0.29
168 INT53814 Regulation of Positive_regulation of Cel 2 0.23 0.45 0.29
169 INT281746 Negative_regulation of Localization of CEL 1 0.03 0.6 0.29
170 INT4130 Regulation of Ces1c 2 0.18 0.36 0.28
171 INT45081 Negative_regulation of Negative_regulation of Acot1 1 0.03 0 0.28
172 INT46357 Regulation of Gene_expression of Acot1 4 0.45 1.1 0.26
173 INT45435 Positive_regulation of Negative_regulation of Acot1 2 0.39 0 0.26
174 INT45434 Negative_regulation of Positive_regulation of Acot1 2 0.41 0 0.25
175 INT175459 Binding of Cel 2 0.11 6.62 0.24
176 INT255780 Negative_regulation of Negative_regulation of ACHE 2 0.43 1.28 0.24
177 INT16158 Protein_catabolism of CEL 1 0.64 0 0.24
178 INT44697 Positive_regulation of Gene_expression of Baat 1 0.42 0.6 0.24
179 INT48022 Protein_catabolism of BCHE 1 0.87 0 0.24
180 INT174101 Protein_catabolism of Ache 3 0.66 2.45 0.22
181 INT133113 Positive_regulation of Positive_regulation of Baat 1 0.46 0.57 0.22
182 INT202425 Negative_regulation of Transcription of CEL 1 0.03 0.49 0.21
183 INT181826 Transcription of Baat 4 0.35 4.43 0.2
184 INT353827 Protein_catabolism of Bche 1 0.05 0 0.2
185 INT255788 Positive_regulation of Aadac 2 0.01 1.39 0.19
186 INT181819 Binding of Baat 2 0.24 0.96 0.19
187 INT1255 Regulation of Binding of Ache 1 0.02 0 0.19
188 INT35620 Positive_regulation of Negative_regulation of ACHE 1 0.48 0 0.17
189 INT147953 Positive_regulation of Positive_regulation of Ache 2 0.46 0.08 0.16
190 INT287253 Regulation of Negative_regulation of ACOT1 1 0.06 0.22 0.15
191 INT227280 Regulation of Gene_expression of Baat 4 0.26 3.82 0.14
192 INT164729 Binding of Mgll 3 0.48 0.2 0.14
193 INT251700 Positive_regulation of Protein_catabolism of Ache 1 0.46 0.44 0.14
194 INT73811 Regulation of Regulation of Acot1 1 0.05 0.07 0.14
195 INT175454 Positive_regulation of Binding of Cel 1 0.15 0.92 0.14
196 INT7652 Localization of Ache 2 0.80 0 0.13
197 INT52420 Negative_regulation of Protein_catabolism of Ache 1 0.04 0.44 0.12
198 INT63907 Regulation of Positive_regulation of Acot1 1 0.20 0.14 0.12
199 INT287252 Positive_regulation of Gene_expression of ACOT1 1 0.05 0.18 0.12
200 INT93878 Positive_regulation of Lipc 4 0.47 3.09 0.11
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