GO:0004102

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Name choline O-acetyltransferase activity
Categary Function
Go Slim No
Go Link GO:0004102
Unique Molecular Interactions 82
Total Molecular Interactions 136
Total Single Events 1353
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for choline O-acetyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported for choline O-acetyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12140 Ngf Regulation of Chat 1 0.44 1.67 2.18
2 INT12138 Ins1 Negative_regulation of Chat 1 0.27 0.71 1.01
3 INT12141 Igf1 Negative_regulation of Chat 1 0.32 0.63 1
4 INT56742 LIF Positive_regulation of Chat 1 0.02 0.2 0.98
5 INT251706 Chat Regulation of Gene_expression of Acot1 1 0.06 1.64 0.85
6 INT251708 Chat Regulation of Acot1 1 0.03 1.64 0.84
7 INT12142 Ins1 Regulation of Chat 1 0.24 0.69 0.84
8 INT18447 Binding of Ache and Chat 2 0.33 0.33 0.73
9 INT68211 Binding of Calca and Chat 1 0.37 0 0.71
10 INT106347 Igf1 Regulation of Chat 1 0.44 0 0.55
11 INT106346 Mtpn Regulation of Chat 1 0.06 0 0.52
12 INT12143 Ngf Positive_regulation of Chat 1 0.45 0.29 0.49
13 INT56736 Cntf Positive_regulation of Chat 1 0.00 0.1 0.49
14 INT56745 CNTF Positive_regulation of Chat 1 0.02 0.1 0.49
15 INT205567 Regulation of Binding of Fgf1 and Chat 1 0.29 0.28 0.41
16 INT205566 Binding of Fgf1 and Chat 1 0.24 0.28 0.41
17 INT61660 Binding of CHAT and CYP21A2 1 0.00 0 0.4
18 INT79504 Binding of Gad1 and Chat 1 0.35 0 0.38
19 INT79507 Binding of Pvalb and Chat 1 0.06 0 0.38
20 INT22722 Binding of Chat and Hc3 1 0.39 0 0.28
21 INT222543 Il1a Regulation of Chat 1 0.01 0.64 0.19
22 INT160929 Chat Positive_regulation of Penk 1 0.35 1.18 0.15
23 INT147863 Binding of CHAT and SLC18A3 1 0.34 0.8 0.14
24 INT347868 Ntf3 Negative_regulation of Negative_regulation of Chat 1 0.03 0.22 0.13
25 INT201721 Ngf Regulation of Chat 1 0.02 0.4 0.1
26 INT251710 Fig4 Regulation of Chat 1 0.03 0.23 0.08
27 INT251705 Fig4 Regulation of Localization of Chat 1 0.05 0.23 0.08
28 INT242601 Gdnf Positive_regulation of Chat 1 0.29 0.15 0.03
29 INT101159 Gene_expression of Bcl2 Positive_regulation of Gene_expression of CHAT 1 0.31 0.96 0.03
30 INT242611 Nrtn Positive_regulation of Chat 1 0.26 0.15 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for choline O-acetyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported in choline O-acetyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6381 Negative_regulation of Chat 51 0.59 19.68 15.86
2 INT4851 Positive_regulation of Chat 53 0.70 9.21 15.11
3 INT16266 Gene_expression of Chat 80 0.67 16.14 15.01
4 INT11945 Regulation of Chat 38 0.62 7.75 14.97
5 INT4736 Gene_expression of Chat 67 0.77 17.15 14.24
6 INT41728 Gene_expression of CHAT 65 0.75 42.19 12.73
7 INT15308 Localization of Chat 29 0.81 2.35 8.47
8 INT42312 Negative_regulation of Chat 14 0.54 6.13 5.44
9 INT48449 Regulation of Chat 11 0.61 4.24 3.64
10 INT47386 Negative_regulation of CHAT 5 0.29 1.63 2.61
11 INT11943 Transcription of Chat 10 0.70 1.55 2.36
12 INT22282 Positive_regulation of Chat 8 0.67 2.82 2.12
13 INT87374 Positive_regulation of CHAT 7 0.67 3.91 1.96
14 INT222970 Localization of Chat 6 0.73 0.96 1.66
15 INT222971 Negative_regulation of Negative_regulation of Chat 1 0.38 1.25 1.53
16 INT32900 Negative_regulation of Positive_regulation of Chat 3 0.43 1.91 1.45
17 INT242532 Positive_regulation of Gene_expression of Chat 14 0.50 2.38 1.44
18 INT58452 Positive_regulation of Negative_regulation of Chat 4 0.50 1.99 1.35
19 INT44621 Binding of Chat 5 0.45 0.87 1.15
20 INT57188 Regulation of Gene_expression of Chat 4 0.45 1.89 1.12
21 INT222968 Negative_regulation of Gene_expression of Chat 8 0.42 1.1 1.1
22 INT227604 Transcription of Chat 4 0.52 1.01 1.08
23 INT57189 Negative_regulation of Gene_expression of Chat 5 0.56 1.35 1.07
24 INT30316 Regulation of CHAT 6 0.43 1.95 0.96
25 INT56200 Negative_regulation of Negative_regulation of Chat 3 0.25 1.38 0.88
26 INT193070 Localization of CHAT 3 0.17 1.03 0.86
27 INT100626 Transcription of CHAT 4 0.51 1.94 0.69
28 INT44622 Positive_regulation of Binding of Chat 3 0.39 0.71 0.68
29 INT88188 Negative_regulation of Transcription of Chat 1 0.51 0 0.68
30 INT242541 Regulation of Gene_expression of Chat 3 0.43 0.67 0.67
31 INT11942 Positive_regulation of Transcription of Chat 2 0.47 0.23 0.54
32 INT106973 Positive_regulation of Gene_expression of CHAT 3 0.44 0.8 0.5
33 INT196398 Protein_catabolism of Chat 1 0.24 2.1 0.47
34 INT85761 Positive_regulation of Gene_expression of Chat 5 0.30 1.43 0.39
35 INT87388 Negative_regulation of Positive_regulation of CHAT 1 0.42 0.41 0.34
36 INT95831 Regulation of Negative_regulation of Chat 1 0.09 0 0.32
37 INT109433 Phosphorylation of Chat 1 0.15 0.65 0.24
38 INT218031 Regulation of Transcription of CHAT 1 0.27 0 0.24
39 INT297457 Regulation of Regulation of Chat 1 0.27 0.32 0.21
40 INT314791 Binding of Chat 1 0.32 0 0.15
41 INT323950 Phosphorylation of Chat 1 0.09 0.93 0.11
42 INT297461 Protein_catabolism of Chat 1 0.39 0.5 0.1
43 INT227603 Negative_regulation of Localization of Chat 1 0.12 0 0.07
44 INT159025 Negative_regulation of Localization of Chat 1 0.39 0 0.04
45 INT226593 Positive_regulation of Positive_regulation of Chat 1 0.20 0.65 0.04
46 INT227602 Negative_regulation of Transcription of Chat 1 0.12 0.18 0
47 INT314792 Positive_regulation of Localization of Chat 1 0.43 0 0
48 INT169264 Regulation of Localization of Chat 1 0.21 0.08 0
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