GO:0004108

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Name citrate (Si)-synthase activity
Categary Function
Go Slim No
Go Link GO:0004108
Unique Molecular Interactions 48
Total Molecular Interactions 74
Total Single Events 202
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for citrate (Si)-synthase activity. They are ordered first by their pain relevance and then by number of times they were reported for citrate (Si)-synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125574 CS Regulation of Ldha 1 0.02 0.23 0.42
2 INT272052 Binding of CS and Cfcd 1 0.00 0.54 0.4
3 INT244452 CS Positive_regulation of Phosphorylation of EIF2S2 1 0.21 2.07 0.09
4 INT244449 CS Regulation of Gene_expression of ATF4 1 0.15 0.83 0.08
5 INT244461 CS Positive_regulation of ESR1 1 0.06 1.15 0.05
6 INT204172 Regulation of Binding of Cs and Nox1 1 0.08 1.01 0.04
7 INT204173 Binding of Cs and Nox1 1 0.07 1 0.04
8 INT244474 CS Regulation of XBP1 1 0.20 0.15 0
9 INT244480 CS Negative_regulation of Gene_expression of XBP1 1 0.16 0.11 0
10 INT244476 CS Positive_regulation of ATF3 1 0.13 0.13 0
11 INT64385 Cs Negative_regulation of PGC 1 0.00 0.15 0
12 INT244469 CS Positive_regulation of PPP1R15A 1 0.08 0.12 0
13 INT244457 CS Positive_regulation of Gene_expression of ESR1 1 0.07 0.67 0
14 INT244458 CS Positive_regulation of ERN1 1 0.17 0.71 0
15 INT244475 Binding of CS and Positive_regulation of EIF2S2 1 0.11 0.07 0
16 INT244477 CS Regulation of Gene_expression of ATF6 1 0.18 0.07 0
17 INT244453 CS Positive_regulation of Gene_expression of TMBIM6 1 0.07 1.3 0
18 INT244479 CS Positive_regulation of ATF6 1 0.17 1.02 0
19 INT244460 Binding of CS and Positive_regulation of Positive_regulation of EIF2S2 1 0.13 0.06 0
20 INT244468 CS Positive_regulation of EIF2S2 1 0.16 0.43 0
21 INT244467 Negative_regulation of CS Positive_regulation of EIF2S2 1 0.11 0.14 0
22 INT244478 Regulation of CS Regulation of XBP1 1 0.20 0.06 0
23 INT244482 CS Positive_regulation of Transcription of ATF3 1 0.13 0.13 0
24 INT244472 CS Negative_regulation of Binding of XBP1 1 0.19 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for citrate (Si)-synthase activity. They are ordered first by their pain relevance and then by number of times they were reported in citrate (Si)-synthase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT26363 Negative_regulation of CS 8 0.26 2.49 2.36
2 INT26364 Positive_regulation of CS 12 0.30 4.99 1.89
3 INT125573 Gene_expression of CS 26 0.41 8 0.98
4 INT9368 Regulation of CS 6 0.17 1.67 0.8
5 INT205274 Gene_expression of Cs 2 0.75 2.08 0.36
6 INT205532 Binding of CS 7 0.14 1.27 0.22
7 INT244569 Phosphorylation of CS 1 0.31 2.96 0.15
8 INT244487 Regulation of Positive_regulation of CS 1 0.10 0.18 0.12
9 INT244553 Positive_regulation of Gene_expression of CS 6 0.22 3.07 0.09
10 INT336476 Positive_regulation of Binding of CS 1 0.09 0 0.09
11 INT205533 Localization of CS 4 0.28 0.69 0.06
12 INT244536 Negative_regulation of Gene_expression of CS 3 0.31 0.88 0.04
13 INT204165 Regulation of Cs 2 0.09 1.35 0.04
14 INT244518 Positive_regulation of Localization of CS 2 0.19 0.37 0.03
15 INT244530 Regulation of Binding of CS 1 0.17 0.06 0
16 INT344633 Negative_regulation of Cs 1 0.42 0.82 0
17 INT244565 Negative_regulation of Phosphorylation of CS 1 0.16 0.24 0
18 INT244515 Regulation of Gene_expression of CS 1 0.20 1.26 0
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