GO:0004115

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Name 3',5'-cyclic-AMP phosphodiesterase activity
Categary Function
Go Slim No
Go Link GO:0004115
Unique Molecular Interactions 103
Total Molecular Interactions 130
Total Single Events 1440
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 3',5'-cyclic-AMP phosphodiesterase activity. They are ordered first by their pain relevance and then by number of times they were reported for 3',5'-cyclic-AMP phosphodiesterase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93234 Negative_regulation of Pde4b Negative_regulation of Gene_expression of Fos 1 0.41 0.1 0.96
2 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
3 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
4 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85
5 INT149925 Negative_regulation of Cpox Negative_regulation of Gene_expression of Pde4d 1 0.01 0.39 0.84
6 INT273350 Pde7a Positive_regulation of Localization of Pde4d 1 0.33 1.35 0.49
7 INT127663 IRF6 Positive_regulation of PDE4A 1 0.14 0.76 0.48
8 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
9 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
10 INT127662 Negative_regulation of PDE4A Negative_regulation of Gene_expression of PTGS2 1 0.15 0.75 0.47
11 INT222923 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of Mpo 1 0.04 0.59 0.45
12 INT222924 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il12a 1 0.01 0.59 0.45
13 INT222922 Negative_regulation of Pde4a Negative_regulation of Gene_expression of Il1 1 0.01 0.56 0.44
14 INT86972 PDE1B Positive_regulation of Localization of Gh 1 0.00 0 0.42
15 INT275100 Pde4a Negative_regulation of RTP3 1 0.00 0.51 0.42
16 INT275089 Pde4a Negative_regulation of stm 1 0.02 0.51 0.42
17 INT273172 Negative_regulation of PDE4A Negative_regulation of Localization of CD4 1 0.11 0.74 0.37
18 INT79383 Pde1b Regulation of Oprd1 1 0.02 0 0.34
19 INT274172 Negative_regulation of Pde4a Negative_regulation of Positive_regulation of TNF 1 0.02 0.72 0.28
20 INT273352 Pde7a Positive_regulation of Localization of Pde4b 1 0.43 0.68 0.24
21 INT30071 Gm8212 Regulation of Pde3a 1 0.00 0 0.2
22 INT196822 Negative_regulation of Adcy5 Positive_regulation of Pde1a 1 0.01 0 0.19
23 INT196815 Adcy5 Positive_regulation of Pde1a 1 0.01 0 0.19
24 INT262361 Binding of Pde4b and DISC1 1 0.08 0.57 0.18
25 INT274169 Mapk1 Regulation of Pde4a 1 0.05 0.62 0.17
26 INT276065 Camk2a Negative_regulation of Pde1b 1 0.56 0 0.17
27 INT219601 Pde4a Negative_regulation of Twist1 1 0.10 0 0.16
28 INT226365 Negative_regulation of PDE4A Negative_regulation of Localization of IL5 1 0.05 0.18 0.16
29 INT219598 Pde4a Negative_regulation of Gene_expression of Twist1 1 0.10 0 0.16
30 INT226382 Negative_regulation of PDE4A Negative_regulation of Localization of IL4 1 0.12 0.18 0.16
31 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15
32 INT219597 Prkaca Positive_regulation of Pde4d 1 0.29 0 0.15
33 INT263178 Binding of PDE7A and COPD 1 0.01 1 0.15
34 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15
35 INT263174 PDE7A Regulation of COPD 1 0.01 1 0.15
36 INT273171 PDE4A Regulation of IL8 1 0.05 0.53 0.15
37 INT276060 Pde1b Regulation of Car2 1 0.30 0 0.15
38 INT263176 Binding of PDE4A and COPD 1 0.01 1 0.15
39 INT87110 Apom Negative_regulation of Pde1a 1 0.00 0 0.15
40 INT273017 Binding of PDE1B and PDE11A 1 0.08 0.35 0.14
41 INT196811 Binding of Pde1a and Adcy5 1 0.01 0 0.14
42 INT196837 Binding of CALM1 and Pde1a 1 0.00 0 0.14
43 INT273185 PDE4A Regulation of Gene_expression of Mmp12 1 0.08 0.57 0.13
44 INT276079 Pde1b Negative_regulation of Camk2a 1 0.41 0 0.12
45 INT219599 Pde4d Regulation of Prkaca 1 0.28 0 0.12
46 INT263173 Binding of PDE7A and Prkaca 1 0.01 0.27 0.09
47 INT219600 Pde4d Regulation of Binding of Prkaca 1 0.28 0 0.09
48 INT219602 Binding of Prkaca and Pde4d 1 0.23 0 0.09
49 INT79446 IL10 Negative_regulation of Transcription of PDE4B 1 0.44 0 0.08
50 INT79445 IL10 Negative_regulation of Gene_expression of PDE4B 1 0.43 0 0.08
51 INT276067 Binding of Car2 and Pde1b 1 0.32 0 0.06
52 INT276050 Binding of Calm3 and Pde1b 1 0.15 0 0.06
53 INT276049 Pde1b Regulation of Positive_regulation of Rpa1 1 0.04 0 0.06
54 INT82578 IRF6 Positive_regulation of Gene_expression of PDE4B 1 0.21 0.09 0.05
55 INT273353 Pde4d Regulation of Gene_expression of Twist1 1 0.26 0.25 0.05
56 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05
57 INT263197 Binding of PDE3A and Pde5a 1 0.03 0.18 0.04
58 INT276038 Camk2a Negative_regulation of Pde1a 1 0.14 0 0.03
59 INT263198 Pde5a Negative_regulation of PDE4A 1 0.09 0.16 0.03
60 INT276036 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Prkaca 1 0.27 0 0.03
61 INT276055 Negative_regulation of Pde1b Positive_regulation of Prkaca 1 0.27 0 0.03
62 INT276070 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Ppp1r1b 1 0.24 0 0.03
63 INT219596 Binding of Pde4a and Pde4d 1 0.28 0.31 0
64 INT276044 Binding of Pde1b and Ppp1cc 1 0.12 0 0
65 INT276048 Binding of Pde1b and Myoz1 1 0.04 0 0
66 INT121478 Binding of Pde3a and Positive_regulation of Localization of Ins1 1 0.24 0 0
67 INT79447 IRF6 Positive_regulation of Transcription of PDE4B 1 0.19 0 0
68 INT276078 Binding of Camk2a and Pde1b 1 0.36 0 0
69 INT263182 Ca2 Positive_regulation of Phosphorylation of Pde1b 1 0.01 0 0
70 INT276052 Negative_regulation of Pde1b Negative_regulation of Camk2a 1 0.41 0 0
71 INT263181 Binding of Pde1a and Pde5a 1 0.03 0 0
72 INT276058 Camk2a Regulation of Pde1b 1 0.26 0 0
73 INT213582 Binding of HSPA8 and PDE4B 1 0.33 0.3 0
74 INT263183 Binding of Pde1b and Pde5a 1 0.03 0 0
75 INT276042 Negative_regulation of Binding of Calm3 and Pde1b 1 0.17 0 0
76 INT276047 Camk2a Regulation of Negative_regulation of Pde1b 1 0.43 0 0
77 INT276051 Pde1b Regulation of Regulation of Car2 1 0.30 0 0
78 INT276071 Pde1b Regulation of Positive_regulation of Camk2a 1 0.43 0 0
79 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 3',5'-cyclic-AMP phosphodiesterase activity. They are ordered first by their pain relevance and then by number of times they were reported in 3',5'-cyclic-AMP phosphodiesterase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT30169 Negative_regulation of Pde4a 107 0.58 81 36.23
2 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59
3 INT105777 Gene_expression of Pde4a 30 0.76 12.67 8.52
4 INT79456 Gene_expression of PDE4A 35 0.77 19.42 7.42
5 INT89309 Negative_regulation of Pde4b 21 0.53 12.81 7.32
6 INT118492 Regulation of Pde4a 7 0.61 6.32 6.04
7 INT105775 Gene_expression of Pde4d 31 0.78 4.18 5.21
8 INT127668 Positive_regulation of PDE4A 12 0.68 8.39 5.13
9 INT121471 Negative_regulation of Pde3a 24 0.34 13.79 4.73
10 INT105779 Gene_expression of Pde4b 7 0.73 3.33 3.91
11 INT165915 Regulation of Negative_regulation of Pde4a 5 0.29 6.72 2.91
12 INT19235 Negative_regulation of PDE1B 11 0.14 2.38 2.81
13 INT98557 Regulation of PDE4A 12 0.44 8.42 2.56
14 INT79399 Gene_expression of Pde4d 6 0.70 2.83 2.51
15 INT1216 Negative_regulation of Pde4b 9 0.41 2.65 2.5
16 INT107489 Negative_regulation of Pde4d 3 0.42 0 2.47
17 INT137270 Positive_regulation of PDE4D 4 0.48 2.48 2.39
18 INT79402 Gene_expression of Pde4b 7 0.74 3 2.38
19 INT135925 Regulation of Pde4b 5 0.41 1.58 2.24
20 INT36642 Negative_regulation of Pde1a 4 0.43 0.89 2.15
21 INT263127 Negative_regulation of PDE7A 13 0.27 8.03 2.13
22 INT107490 Positive_regulation of Pde4d 3 0.69 0.07 2.13
23 INT105776 Negative_regulation of Gene_expression of Pde4d 5 0.59 2.2 2.01
24 INT135928 Positive_regulation of Binding of Pde4b 3 0.45 0.18 1.81
25 INT79401 Regulation of Gene_expression of Pde4b 4 0.59 1.26 1.8
26 INT153606 Localization of Pde4a 2 0.69 1.23 1.79
27 INT119905 Negative_regulation of PDE3A 5 0.18 5 1.77
28 INT135929 Positive_regulation of Pde4b 3 0.47 0.09 1.7
29 INT135930 Regulation of Gene_expression of Pde4a 3 0.61 0.52 1.63
30 INT135927 Positive_regulation of Pde4a 1 0.68 0 1.6
31 INT177525 Negative_regulation of Negative_regulation of Pde4a 5 0.28 5.22 1.58
32 INT259631 Negative_regulation of PDE4B 4 0.10 4.88 1.54
33 INT79455 Positive_regulation of Gene_expression of PDE4A 3 0.67 2.07 1.5
34 INT135932 Regulation of Gene_expression of Pde4b 1 0.58 0 1.37
35 INT68451 Localization of Pde1b 4 0.22 0 1.35
36 INT135924 Positive_regulation of Gene_expression of Pde4d 2 0.59 0 1.28
37 INT64562 Positive_regulation of Pde1a 2 0.06 0.28 1.28
38 INT73011 Gene_expression of Pde1b 3 0.23 0.38 1.27
39 INT105908 Gene_expression of PDE7A 21 0.78 4.49 1.26
40 INT149924 Negative_regulation of Gene_expression of Pde4d 1 0.26 0.81 1.24
41 INT177527 Negative_regulation of Binding of Pde4a 4 0.28 3.5 1.23
42 INT135926 Binding of Pde4b 5 0.34 0.93 1.21
43 INT209138 Negative_regulation of Negative_regulation of PDE4A 4 0.42 3.84 1.21
44 INT67852 Negative_regulation of Pde1a 1 0.25 0.18 1.2
45 INT40345 Positive_regulation of Pde4b 5 0.67 2.96 1.19
46 INT110400 Negative_regulation of Pde1b 21 0.50 0.58 1.14
47 INT79407 Positive_regulation of Gene_expression of Pde4b 1 0.67 0.38 1.13
48 INT79454 Gene_expression of PDE4B 12 0.77 1.72 1.11
49 INT219595 Positive_regulation of Gene_expression of Pde4a 3 0.39 2.81 1.11
50 INT105778 Negative_regulation of Gene_expression of Pde4b 3 0.38 1.05 1.1
51 INT105774 Negative_regulation of Gene_expression of Pde4a 3 0.42 0.4 1.03
52 INT139117 Negative_regulation of Gene_expression of PDE4A 4 0.42 2.28 1.02
53 INT219589 Binding of Pde4d 13 0.47 0.51 1.01
54 INT219568 Positive_regulation of Pde4d 9 0.49 1.74 1
55 INT69302 Positive_regulation of Pde1b 3 0.21 0.99 0.97
56 INT209144 Positive_regulation of PDE4B 4 0.45 2.03 0.95
57 INT177531 Binding of Pde4a 4 0.29 2.46 0.91
58 INT48340 Regulation of Pde8a 1 0.16 0 0.91
59 INT1217 Regulation of Pde4b 1 0.06 0 0.9
60 INT127669 Regulation of Negative_regulation of PDE4A 4 0.45 2.74 0.88
61 INT263129 Positive_regulation of Negative_regulation of PDE4A 3 0.35 2.92 0.86
62 INT40344 Positive_regulation of Pde8a 1 0.55 1.16 0.85
63 INT265568 Binding of PDE4D 1 0.05 0.81 0.85
64 INT226473 Negative_regulation of PDE4D 5 0.19 3.54 0.83
65 INT135931 Regulation of Regulation of Pde4a 1 0.44 0 0.81
66 INT219578 Negative_regulation of Pde4d 3 0.46 2.95 0.8
67 INT135923 Regulation of Gene_expression of Pde4d 2 0.44 0 0.8
68 INT118753 Regulation of Negative_regulation of Pde4d 1 0.02 0 0.8
69 INT177533 Negative_regulation of Binding of Pde3a 1 0.21 2.46 0.76
70 INT222919 Regulation of Negative_regulation of Pde4b 2 0.41 2.35 0.67
71 INT235846 Transcription of Pde4a 2 0.30 0.88 0.66
72 INT162911 Gene_expression of PDE3A 2 0.24 2.47 0.65
73 INT219580 Localization of Pde4d 5 0.73 2.07 0.64
74 INT213617 Gene_expression of PDE4D 3 0.53 1.98 0.62
75 INT86971 Localization of PDE1B 4 0.15 0.08 0.6
76 INT40343 Negative_regulation of Pde8a 2 0.46 1.11 0.6
77 INT79398 Transcription of Pde4b 1 0.51 0.18 0.57
78 INT79403 Positive_regulation of Transcription of Pde4b 1 0.45 0.18 0.57
79 INT79397 Positive_regulation of Gene_expression of Pde4d 1 0.45 0.2 0.55
80 INT219573 Positive_regulation of Localization of Pde4d 2 0.49 1.39 0.5
81 INT273179 Localization of PDE4D 1 0.34 2.01 0.5
82 INT209136 Regulation of Gene_expression of PDE4A 3 0.27 1.63 0.49
83 INT273345 Gene_expression of Pde7a 1 0.65 1.45 0.47
84 INT222921 Protein_catabolism of Pde4a 1 0.07 1.78 0.47
85 INT121469 Binding of Pde3a 2 0.23 1.42 0.44
86 INT273344 Negative_regulation of Pde7a 1 0.49 1.36 0.43
87 INT40342 Negative_regulation of Positive_regulation of Pde8a 1 0.46 0.58 0.42
88 INT86970 Positive_regulation of Localization of PDE1B 1 0.00 0 0.42
89 INT79450 Positive_regulation of Gene_expression of PDE4B 6 0.50 0.6 0.41
90 INT103316 Localization of PDE4A 2 0.68 1.76 0.41
91 INT105906 Transcription of PDE7A 8 0.72 1.21 0.39
92 INT219565 Regulation of Pde4d 3 0.44 0.5 0.39
93 INT275542 Regulation of Gene_expression of PDE7A 1 0.12 1.98 0.39
94 INT275538 Regulation of PDE7A 1 0.12 1.97 0.39
95 INT273326 Transcription of Pde4b 3 0.62 0.99 0.38
96 INT273347 Negative_regulation of Gene_expression of Pde7a 1 0.36 1.3 0.38
97 INT79379 Regulation of Pde1b 1 0.07 0 0.37
98 INT209137 Negative_regulation of Positive_regulation of PDE4A 1 0.42 0.8 0.37
99 INT273330 Positive_regulation of Negative_regulation of Pde4d 1 0.39 1.25 0.35
100 INT242948 Gene_expression of PDE1B 1 0.02 0.91 0.34
101 INT235849 Regulation of Transcription of Pde4a 1 0.01 0.15 0.33
102 INT276012 Gene_expression of Pde1b 8 0.66 0.58 0.32
103 INT276027 Positive_regulation of Pde1b 7 0.59 0.71 0.32
104 INT219588 Negative_regulation of Gene_expression of Pde3a 1 0.25 0 0.32
105 INT219563 Gene_expression of Pde3a 1 0.39 0 0.32
106 INT257213 Binding of PDE4A 5 0.36 1.69 0.3
107 INT209140 Transcription of PDE4A 3 0.71 0.59 0.26
108 INT82579 Regulation of Gene_expression of PDE4B 1 0.45 0.15 0.25
109 INT273339 Positive_regulation of Localization of Pde4b 1 0.45 0.7 0.25
110 INT82581 Regulation of PDE4B 1 0.45 0.15 0.25
111 INT273341 Transcription of Pde4d 2 0.54 0.68 0.24
112 INT263139 Positive_regulation of Negative_regulation of PDE7A 1 0.23 0.65 0.24
113 INT273329 Regulation of Negative_regulation of Pde7a 1 0.38 0.68 0.24
114 INT273348 Localization of Pde4b 1 0.68 0.66 0.24
115 INT263124 Positive_regulation of Regulation of PDE4A 1 0.26 0.65 0.24
116 INT273336 Regulation of Negative_regulation of Pde4d 1 0.35 0.68 0.24
117 INT100251 Regulation of PDE1B 4 0.26 1.21 0.22
118 INT263125 Regulation of Negative_regulation of PDE7A 1 0.28 0.72 0.21
119 INT79452 Transcription of PDE4B 1 0.52 0 0.21
120 INT273181 Negative_regulation of Localization of PDE4D 1 0.18 0.68 0.2
121 INT30069 Regulation of Pde3a 1 0.06 0 0.2
122 INT263133 Positive_regulation of Gene_expression of PDE7A 2 0.21 0.56 0.19
123 INT275543 Negative_regulation of Gene_expression of PDE4D 1 0.11 0.87 0.19
124 INT263128 Negative_regulation of Binding of PDE4A 3 0.22 1.33 0.18
125 INT166869 Positive_regulation of Pde1a 2 0.59 0.74 0.18
126 INT188310 Binding of Pde4b 2 0.06 0.77 0.18
127 INT263126 Negative_regulation of Binding of PDE3A 1 0.13 0.62 0.18
128 INT219576 Positive_regulation of Gene_expression of Pde3a 1 0.29 0 0.17
129 INT242946 Positive_regulation of Phosphorylation of PDE1B 1 0.01 0.22 0.17
130 INT273332 Positive_regulation of Negative_regulation of Pde4b 1 0.45 0.49 0.17
131 INT105907 Positive_regulation of Transcription of PDE7A 4 0.47 0.53 0.16
132 INT275085 Transcription of PDE1B 1 0.04 0.27 0.16
133 INT273346 Positive_regulation of Gene_expression of Pde4b 1 0.45 0.47 0.16
134 INT273184 Localization of PDE4B 1 0.29 0.61 0.14
135 INT274166 Phosphorylation of Pde4a 1 0.30 1.1 0.13
136 INT219593 Regulation of Binding of Pde4d 1 0.44 0 0.13
137 INT79451 Positive_regulation of Transcription of PDE4B 1 0.45 0 0.13
138 INT179449 Binding of PDE1B 5 0.07 0.3 0.11
139 INT263130 Phosphorylation of PDE4A 2 0.42 0.67 0.11
140 INT196773 Negative_regulation of Positive_regulation of Pde1a 1 0.01 0 0.11
141 INT263122 Binding of PDE7A 1 0.22 0.27 0.1
142 INT219574 Phosphorylation of Pde4d 1 0.79 0.33 0.1
143 INT275587 Regulation of Negative_regulation of PDE4B 1 0.08 0.89 0.1
144 INT263134 Binding of PDE3A 1 0.15 0.47 0.09
145 INT273349 Regulation of Gene_expression of Pde7a 1 0.38 0.32 0.08
146 INT242947 Phosphorylation of PDE1B 1 0.02 0.11 0.08
147 INT100247 Positive_regulation of PDE1B 2 0.40 0.65 0.07
148 INT276000 Negative_regulation of Positive_regulation of Pde1b 2 0.36 0.54 0.06
149 INT273340 Transcription of Pde7a 1 0.57 0.08 0.06
150 INT273327 Positive_regulation of Pde7a 1 0.39 0.08 0.06
151 INT219585 Positive_regulation of Positive_regulation of Pde4d 1 0.43 0 0.06
152 INT275994 Positive_regulation of Negative_regulation of Pde1b 1 0.43 0 0.06
153 INT274162 Negative_regulation of Phosphorylation of Pde4a 1 0.16 0.8 0.04
154 INT79487 Negative_regulation of Gene_expression of Pde4b 1 0.07 0.65 0.04
155 INT19234 Positive_regulation of Negative_regulation of PDE1B 1 0.01 0.05 0.04
156 INT209139 Regulation of Transcription of PDE4A 1 0.61 0.28 0.04
157 INT275993 Negative_regulation of Gene_expression of Pde1b 2 0.36 0.53 0.03
158 INT276029 Regulation of Negative_regulation of Pde1b 1 0.38 0 0.03
159 INT276013 Phosphorylation of Pde1a 1 0.18 0 0.03
160 INT263142 Positive_regulation of Negative_regulation of PDE3A 1 0.15 0.15 0.03
161 INT275998 Positive_regulation of Gene_expression of Pde1b 1 0.43 0 0.03
162 INT263131 Localization of PDE3A 1 0.23 0.35 0.03
163 INT263191 Gene_expression of Pde1a 7 0.21 0.33 0
164 INT248265 Regulation of Pde4d 1 0.21 0.87 0
165 INT100252 Regulation of Regulation of PDE1B 1 0.26 0.55 0
166 INT162919 Regulation of Transcription of PDE3A 1 0.06 0 0
167 INT219583 Regulation of Binding of Pde4b 1 0.30 0 0
168 INT276008 Negative_regulation of Localization of Pde1b 1 0.36 0 0
169 INT263141 Regulation of Localization of PDE7A 1 0.21 0 0
170 INT162923 Regulation of PDE3A 1 0.06 0 0
171 INT276007 Negative_regulation of Phosphorylation of Pde1b 1 0.36 0 0
172 INT276001 Positive_regulation of Phosphorylation of Pde1b 1 0.40 0 0
173 INT162902 Positive_regulation of Protein_catabolism of PDE1B 1 0.11 0 0
174 INT219569 Regulation of Binding of Pde4a 1 0.35 0 0
175 INT219570 Negative_regulation of Positive_regulation of Pde4d 1 0.42 0 0
176 INT263132 Phosphorylation of PDE3A 1 0.25 0.19 0
177 INT276006 Phosphorylation of Pde1b 1 0.70 0 0
178 INT275991 Regulation of Phosphorylation of Pde1b 1 0.38 0 0
179 INT162908 Protein_catabolism of PDE1B 1 0.19 0 0
180 INT276011 Localization of Pde1b 1 0.64 0 0
181 INT263119 Positive_regulation of Phosphorylation of PDE3A 1 0.21 0.19 0
182 INT219575 Positive_regulation of Binding of Pde4d 1 0.49 0 0
183 INT263123 Positive_regulation of PDE3A 1 0.21 0.19 0
184 INT213588 Binding of PDE4B 1 0.33 0 0
185 INT276023 Positive_regulation of Positive_regulation of Pde1b 1 0.43 0 0
186 INT263136 Positive_regulation of Positive_regulation of PDE3A 1 0.21 0.19 0
187 INT275999 Binding of Pde1b 1 0.32 0 0
188 INT162904 Transcription of PDE3A 1 0.07 0 0
189 INT263140 Localization of PDE7A 1 0.35 0 0
190 INT263186 Phosphorylation of Pde1b 1 0.24 0 0
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