GO:0004119

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Name cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
Categary Function
Go Slim No
Go Link GO:0004119
Unique Molecular Interactions 5
Total Molecular Interactions 5
Total Single Events 78
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cGMP-inhibited cyclic-nucleotide phosphodiesterase activity. They are ordered first by their pain relevance and then by number of times they were reported for cGMP-inhibited cyclic-nucleotide phosphodiesterase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT30071 Gm8212 Regulation of Pde3a 1 0.00 0 0.2
2 INT263179 PDE3A Regulation of COPD 1 0.00 1 0.15
3 INT263177 Binding of PDE3A and COPD 1 0.01 1 0.15
4 INT263197 Binding of PDE3A and Pde5a 1 0.03 0.18 0.04
5 INT121478 Binding of Pde3a and Positive_regulation of Localization of Ins1 1 0.24 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cGMP-inhibited cyclic-nucleotide phosphodiesterase activity. They are ordered first by their pain relevance and then by number of times they were reported in cGMP-inhibited cyclic-nucleotide phosphodiesterase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT121471 Negative_regulation of Pde3a 24 0.34 13.79 4.73
2 INT119905 Negative_regulation of PDE3A 5 0.18 5 1.77
3 INT177533 Negative_regulation of Binding of Pde3a 1 0.21 2.46 0.76
4 INT162911 Gene_expression of PDE3A 2 0.24 2.47 0.65
5 INT121469 Binding of Pde3a 2 0.23 1.42 0.44
6 INT219588 Negative_regulation of Gene_expression of Pde3a 1 0.25 0 0.32
7 INT219563 Gene_expression of Pde3a 1 0.39 0 0.32
8 INT30069 Regulation of Pde3a 1 0.06 0 0.2
9 INT263126 Negative_regulation of Binding of PDE3A 1 0.13 0.62 0.18
10 INT219576 Positive_regulation of Gene_expression of Pde3a 1 0.29 0 0.17
11 INT263134 Binding of PDE3A 1 0.15 0.47 0.09
12 INT263142 Positive_regulation of Negative_regulation of PDE3A 1 0.15 0.15 0.03
13 INT263131 Localization of PDE3A 1 0.23 0.35 0.03
14 INT162919 Regulation of Transcription of PDE3A 1 0.06 0 0
15 INT162923 Regulation of PDE3A 1 0.06 0 0
16 INT263132 Phosphorylation of PDE3A 1 0.25 0.19 0
17 INT263119 Positive_regulation of Phosphorylation of PDE3A 1 0.21 0.19 0
18 INT263123 Positive_regulation of PDE3A 1 0.21 0.19 0
19 INT263136 Positive_regulation of Positive_regulation of PDE3A 1 0.21 0.19 0
20 INT162904 Transcription of PDE3A 1 0.07 0 0
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