GO:0004129

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Name cytochrome-c oxidase activity
Categary Function
Go Slim No
Go Link GO:0004129
Unique Molecular Interactions 10
Total Molecular Interactions 10
Total Single Events 195
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cytochrome-c oxidase activity. They are ordered first by their pain relevance and then by number of times they were reported for cytochrome-c oxidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT96228 COX5A Regulation of Ak1 1 0.01 0.6 0.6
2 INT113113 COX5A Regulation of Gene_expression of MRXS5 1 0.10 0.9 0.45
3 INT136749 COX5A Positive_regulation of Gene_expression of SCARB1 1 0.52 0.36 0.45
4 INT285327 Binding of Cox8b and Gtf2ird2 1 0.00 0.9 0.29
5 INT238264 pma Negative_regulation of Gene_expression of Cr1l 1 0.02 0.26 0.16
6 INT238262 Prkcg Negative_regulation of Gene_expression of Cr1l 1 0.12 0.26 0.16
7 INT157559 Nrf1 Regulation of COX5A 1 0.18 0 0.15
8 INT191432 Binding of COX10 and EDIL3 1 0.01 1.79 0.1
9 INT158506 COX5A Negative_regulation of PTGS1 1 0.06 0.18 0
10 INT279514 Cr1l Negative_regulation of INCENP 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cytochrome-c oxidase activity. They are ordered first by their pain relevance and then by number of times they were reported in cytochrome-c oxidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63
2 INT78404 Gene_expression of COX5A 24 0.75 9.73 7.07
3 INT131152 Gene_expression of Cr1l 17 0.75 10.83 4.88
4 INT108823 Binding of COX5A 8 0.47 4.06 4.14
5 INT93911 Regulation of COX5A 11 0.60 4.94 4.05
6 INT133747 Positive_regulation of COX5A 5 0.49 1.9 2.57
7 INT133746 Negative_regulation of Positive_regulation of COX5A 2 0.41 2.46 1.58
8 INT112832 Negative_regulation of Gene_expression of COX5A 4 0.41 2.68 1.51
9 INT138815 Regulation of Binding of COX5A 3 0.44 1.06 1.29
10 INT94514 Localization of COX5A 3 0.78 0.54 0.9
11 INT163360 Positive_regulation of Cr1l 2 0.49 0.89 0.8
12 INT181407 Regulation of Cr1l 1 0.02 0.61 0.67
13 INT91467 Negative_regulation of Negative_regulation of COX5A 2 0.41 0.89 0.64
14 INT129834 Positive_regulation of Gene_expression of COX5A 1 0.49 0.54 0.59
15 INT131153 Negative_regulation of Gene_expression of Cr1l 2 0.41 0.83 0.52
16 INT129549 Negative_regulation of Binding of COX5A 1 0.41 0.38 0.37
17 INT285324 Negative_regulation of Cox8b 1 0.07 1.59 0.37
18 INT129548 Positive_regulation of Binding of COX5A 1 0.49 0.38 0.37
19 INT297298 Regulation of Gene_expression of Cr1l 1 0.26 0.91 0.32
20 INT179544 Negative_regulation of Cr1l 3 0.42 0.67 0.29
21 INT74782 Transcription of COX5A 2 0.69 1.13 0.24
22 INT157558 Positive_regulation of Regulation of COX5A 1 0.49 0 0.18
23 INT238243 Transcription of Cr1l 1 0.52 0.19 0.18
24 INT285326 Localization of Cox8b 1 0.10 0.16 0.15
25 INT285322 Negative_regulation of Localization of Cox8b 1 0.06 0.16 0.15
26 INT117962 Positive_regulation of Negative_regulation of COX5A 1 0.02 0.69 0.13
27 INT323363 Protein_catabolism of COX5A 1 0.02 0.53 0.12
28 INT238244 Positive_regulation of Positive_regulation of Cr1l 1 0.49 0.34 0.11
29 INT112243 Negative_regulation of Transcription of COX5A 1 0.57 0.89 0.11
30 INT175415 Negative_regulation of COX10 5 0.07 3.33 0.08
31 INT229939 Binding of Cr1l 1 0.35 0.07 0.04
32 INT223610 Binding of COX10 1 0.05 0.46 0
33 INT223595 Negative_regulation of Binding of COX10 1 0.05 0.47 0
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