GO:0004143

From wiki-pain
Jump to: navigation, search
Name diacylglycerol kinase activity
Categary Function
Go Slim No
Go Link GO:0004143
Unique Molecular Interactions 19
Total Molecular Interactions 21
Total Single Events 373
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for diacylglycerol kinase activity. They are ordered first by their pain relevance and then by number of times they were reported for diacylglycerol kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
2 INT294766 Cerk Regulation of Gene_expression of Hand2 1 0.13 0.32 0.15
3 INT294763 Binding of Gopc and Cerk 1 0.14 0.37 0.14
4 INT294764 Binding of Hand2 and Cerk 1 0.17 0.31 0.14
5 INT294761 Binding of Hand1 and Cerk 1 0.23 0.36 0.14
6 INT294760 Cerk Positive_regulation of Hand2 1 0.23 0.16 0.12
7 INT294758 Regulation of Cerk Positive_regulation of Hand2 1 0.21 0.16 0.12
8 INT244640 AGK Negative_regulation of KIT 1 0.00 0.69 0.08
9 INT244639 AGK Negative_regulation of PDGFRB 1 0.01 0.69 0.08
10 INT244638 AGK Negative_regulation of KDR 1 0.00 0.68 0.08
11 INT337812 Dgkb Regulation of Igkv4-54 1 0.07 1.27 0.08
12 INT251775 AGK Negative_regulation of INSRR 1 0.00 1.1 0.07
13 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
14 INT351029 AGK Regulation of VEGFA 1 0.00 0.82 0
15 INT287673 Negative_regulation of Sphk1 Negative_regulation of Akt1 1 0.20 0.42 0
16 INT335526 SPHK1 Regulation of Gene_expression of SGCB 1 0.27 0.86 0
17 INT335525 Binding of SGCB and SPHK1 1 0.22 1.61 0
18 INT351030 AGK Regulation of ARAF 1 0.00 0.82 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for diacylglycerol kinase activity. They are ordered first by their pain relevance and then by number of times they were reported in diacylglycerol kinase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
2 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
3 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
4 INT337804 Binding of Dgkb 1 0.37 9.46 1.65
5 INT337808 Gene_expression of Dgkb 1 0.66 13.46 1.57
6 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18
7 INT24372 Negative_regulation of Sphk1 1 0.59 0 0.85
8 INT337806 Regulation of Dgkb 1 0.53 4.53 0.69
9 INT24373 Gene_expression of Sphk1 3 0.67 0 0.68
10 INT294751 Negative_regulation of Cerk 1 0.43 2.52 0.57
11 INT337805 Phosphorylation of Dgkb 1 0.80 2.89 0.51
12 INT24375 Regulation of Sphk1 1 0.62 0 0.5
13 INT337793 Negative_regulation of Binding of Dgkb 1 0.42 4.29 0.49
14 INT24371 Positive_regulation of Sphk1 2 0.41 2.37 0.46
15 INT337790 Negative_regulation of Gene_expression of Dgkb 1 0.36 3.75 0.4
16 INT337798 Transcription of Dgkb 1 0.68 1.9 0.37
17 INT337799 Regulation of Binding of Dgkb 1 0.39 1.06 0.36
18 INT24374 Regulation of Gene_expression of Sphk1 1 0.45 0 0.31
19 INT337791 Regulation of Regulation of Dgkb 1 0.39 0.78 0.29
20 INT337788 Positive_regulation of Gene_expression of Dgkb 1 0.43 0.73 0.29
21 INT294752 Gene_expression of Cerk 1 0.67 1.96 0.28
22 INT337792 Positive_regulation of Binding of Dgkb 1 0.43 1.32 0.28
23 INT302791 Negative_regulation of Gene_expression of Sphk1 1 0.23 0.34 0.24
24 INT294755 Regulation of Cerk 1 0.45 1.23 0.23
25 INT337802 Negative_regulation of Dgkb 1 0.50 3.2 0.23
26 INT280593 Negative_regulation of Gene_expression of SPHK1 2 0.43 3.92 0.19
27 INT280594 Gene_expression of SPHK1 2 0.78 71.47 0.19
28 INT287672 Positive_regulation of Positive_regulation of Sphk1 1 0.48 0.38 0.14
29 INT280581 Regulation of SPHK1 2 0.45 1.33 0.13
30 INT280589 Localization of SPHK1 2 0.75 2.61 0.13
31 INT158618 Binding of Sphk1 1 0.01 0 0.13
32 INT294750 Negative_regulation of Negative_regulation of Cerk 1 0.43 0.17 0.12
33 INT287665 Regulation of Negative_regulation of Sphk1 1 0.43 0.11 0.1
34 INT337797 Regulation of Transcription of Dgkb 1 0.39 0.31 0.08
35 INT337800 Negative_regulation of Regulation of Dgkb 1 0.36 1 0.08
36 INT337796 Localization of Dgkb 1 0.64 1.31 0.08
37 INT337803 Positive_regulation of Dgkb 1 0.43 1.28 0.08
38 INT161383 Binding of AGK 1 0.32 0.68 0.08
39 INT278055 Negative_regulation of AGK 2 0.01 2.1 0
40 INT287663 Localization of Sphk1 1 0.72 0.84 0
41 INT335530 Positive_regulation of Gene_expression of SPHK1 1 0.69 21.31 0
42 INT335533 Negative_regulation of SPHK1 1 0.59 2.38 0
43 INT335531 Phosphorylation of SPHK1 1 0.81 1 0
44 INT335529 Transcription of SPHK1 1 0.53 0.74 0
45 INT294747 Positive_regulation of Cerk 1 0.50 0.32 0
46 INT335539 Regulation of Gene_expression of SPHK1 1 0.62 4.55 0
47 INT287668 Regulation of Sphk1 1 0.43 0.66 0
48 INT287664 Binding of Sphk1 1 0.36 0.97 0
49 INT335535 Positive_regulation of SPHK1 1 0.69 12.71 0
50 INT287661 Regulation of Positive_regulation of Sphk1 1 0.43 0 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox