GO:0004146

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Name dihydrofolate reductase activity
Categary Function
Go Slim No
Go Link GO:0004146
Unique Molecular Interactions 16
Total Molecular Interactions 20
Total Single Events 68
Pain Genes Associated 1

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dihydrofolate reductase activity. They are ordered first by their pain relevance and then by number of times they were reported for dihydrofolate reductase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT323278 Dhfr Negative_regulation of Negative_regulation of Igkv1-131 1 0.02 0.93 1.02
2 INT323280 Dhfr Negative_regulation of Igkv1-131 1 0.02 0.47 0.51
3 INT28863 Mtr Negative_regulation of Dhfr 1 0.04 0.87 0.45
4 INT28864 Mtx1 Negative_regulation of Dhfr 1 0.19 0.87 0.44

Single Events

The table below shows the top 100 pain related interactions that have been reported for dihydrofolate reductase activity. They are ordered first by their pain relevance and then by number of times they were reported in dihydrofolate reductase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12290 Gene_expression of Dhfr 7 0.76 2.04 1.47
2 INT285339 Negative_regulation of Gene_expression of Dhfr 1 0.11 1.93 0.65
3 INT285337 Regulation of Gene_expression of Dhfr 1 0.11 1.93 0.65
4 INT323258 Positive_regulation of Dhfr 1 0.20 0.66 0.49
5 INT241468 Binding of Dhfr 2 0.13 1.41 0.17
6 INT57182 Negative_regulation of Dhfr 2 0.55 0.37 0.16
7 INT299472 Positive_regulation of Gene_expression of Dhfr 1 0.20 0 0
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