GO:0004177

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Name aminopeptidase activity
Categary Function
Go Slim No
Go Link GO:0004177
Unique Molecular Interactions 251
Total Molecular Interactions 349
Total Single Events 3072
Pain Genes Associated 37

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for aminopeptidase activity. They are ordered first by their pain relevance and then by number of times they were reported for aminopeptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT247601 Binding of PEPD and SCN9A 1 0.15 2.26 2.27
2 INT54488 Npepo Regulation of Gene_expression of Jun 1 0.30 0 1.98
3 INT54484 Npepo Positive_regulation of Gene_expression of Fos 1 0.43 0 1.63
4 INT342993 PHEX Regulation of Protein_catabolism of SFTPA1 1 0.00 2.84 1.58
5 INT201950 IFNA1 Positive_regulation of Binding of DPP4 1 0.12 2.17 1.47
6 INT201946 IFNA1 Positive_regulation of DPP4 1 0.17 2.16 1.46
7 INT54490 Npepo Positive_regulation of Gene_expression of Pdyn 1 0.06 0 1.35
8 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
9 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
10 INT34422 Cck Positive_regulation of Negative_regulation of Npepo 1 0.31 0 1.14
11 INT54486 Npepo Positive_regulation of Gene_expression of Rabep2 1 0.14 0 1.08
12 INT172757 Rnpep Positive_regulation of Hps4 1 0.00 0 1.08
13 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98
14 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88
15 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87
16 INT124427 NPEPPS Positive_regulation of Protein_catabolism of COL7A1 1 0.00 0.56 0.84
17 INT61130 LTA4H Positive_regulation of CPQ 1 0.28 0 0.83
18 INT16438 Atp6v0d2 Regulation of Localization of Lnpep 1 0.01 0 0.81
19 INT16435 Ubqln1 Regulation of Localization of Lnpep 1 0.01 0 0.81
20 INT141605 Gene_expression of Ctsl Positive_regulation of Positive_regulation of MET 1 0.34 0 0.8
21 INT84466 DPP4 Regulation of Localization of Naga 1 0.00 0.87 0.78
22 INT201947 IFNA1 Positive_regulation of Gene_expression of DPP4 1 0.11 1.09 0.74
23 INT163946 Binding of ERAP1 and Il23r 1 0.23 0.56 0.72
24 INT160711 Binding of KIR3DL1 and ERAP1 1 0.15 0.71 0.71
25 INT12052 Xcl1 Negative_regulation of Rnpep 1 0.01 0 0.71
26 INT28079 POMC Regulation of ANPEP 1 0.08 0.16 0.66
27 INT223865 Enpep Positive_regulation of Ltp 1 0.02 0 0.59
28 INT224724 Gm2458 Negative_regulation of Metap2 1 0.02 1.57 0.57
29 INT19690 Enpep Regulation of Negative_regulation of Penk 1 0.28 0 0.54
30 INT45425 Npepo Regulation of Prl 2 0.32 0.16 0.53
31 INT256019 Agt Negative_regulation of Lnpep 1 0.23 1.76 0.53
32 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
33 INT348177 Binding of HLA-B and ERAP1 1 0.14 0.92 0.49
34 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
35 INT116610 Positive_regulation of Lnpep Regulation of Nos2 1 0.16 0.62 0.44
36 INT116608 Lnpep Regulation of Nos2 1 0.14 0.62 0.44
37 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
38 INT116609 Lnpep Negative_regulation of Bcl2 1 0.05 0.62 0.43
39 INT321046 Anpep Regulation of Negative_regulation of Hps4 1 0.02 0.25 0.43
40 INT116606 Lnpep Regulation of Gene_expression of Bcl2 1 0.07 0.62 0.43
41 INT116607 Lnpep Negative_regulation of Gene_expression of Bcl2 1 0.10 0.62 0.43
42 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
43 INT60063 IL1B Regulation of NPEPPS 1 0.00 0.29 0.42
44 INT299041 SPARC Regulation of Gene_expression of NPEPPS 1 0.01 0.83 0.42
45 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
46 INT148548 Cd44 Positive_regulation of Regulation of NPEPPS 1 0.00 0.29 0.42
47 INT201943 Regulation of Binding of DPP4 and CXCL10 1 0.20 0.58 0.42
48 INT116611 Lnpep Positive_regulation of Binding of Nos2 1 0.16 0.62 0.42
49 INT148547 Cd44 Positive_regulation of NPEPPS 1 0.00 0.29 0.41
50 INT302825 Binding of Creb1 and Xpnpep1 1 0.00 0.64 0.39
51 INT201948 Binding of DPP4 and CXCL10 1 0.27 0.54 0.39
52 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
53 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37
54 INT4220 Npepo Negative_regulation of Prl 1 0.30 0 0.37
55 INT95644 PROC Negative_regulation of NPEPPS 1 0.00 1.24 0.35
56 INT14062 Binding of POMC and RNPEP 1 0.01 0 0.33
57 INT110350 Positive_regulation of Arigg3 Positive_regulation of Positive_regulation of Dpp4 1 0.01 0 0.33
58 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32
59 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32
60 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32
61 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
62 INT222690 TNF Positive_regulation of Gene_expression of NPEPPS 1 0.01 1.03 0.3
63 INT45422 Npepo Regulation of Localization of Prl 1 0.32 0 0.29
64 INT45544 Ncapg2 Regulation of Localization of Lnpep 1 0.00 0 0.28
65 INT45541 Agt Positive_regulation of Lnpep 1 0.03 0 0.27
66 INT33584 Enpep Positive_regulation of Cpe 1 0.03 0 0.27
67 INT256000 H7 Negative_regulation of Rnpep 1 0.00 0.26 0.27
68 INT255995 Binding of H7 and Negative_regulation of Rnpep 1 0.00 0.26 0.27
69 INT33583 Enpep Regulation of Positive_regulation of Cpe 1 0.03 0 0.27
70 INT256028 Binding of Agt and Lnpep 1 0.19 1.16 0.24
71 INT160464 Binding of Mme and Lnpep 1 0.31 0.37 0.24
72 INT326404 Binding of Cck and Enpep 1 0.01 0.19 0.23
73 INT17088 Binding of Ttpa and C9orf3 2 0.38 0.7 0.22
74 INT185142 Rnpep Regulation of Snrpd1 1 0.01 0 0.22
75 INT321980 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Ins1 1 0.16 0.81 0.22
76 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19
77 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19
78 INT51034 Slc30a2 Positive_regulation of Enpep 1 0.01 0 0.19
79 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19
80 INT223424 Binding of Rnpep and Lta4h 1 0.02 0.37 0.19
81 INT42467 PTGER1 Negative_regulation of LNPEP 1 0.02 0 0.18
82 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18
83 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16
84 INT111863 Negative_regulation of Binding of AGT and LNPEP 1 0.09 0 0.16
85 INT111861 Binding of AGT and LNPEP 1 0.07 0 0.16
86 INT105253 Positive_regulation of Binding of Rnpep and F2rl1 1 0.02 0 0.15
87 INT167523 Binding of Pepd and Aaas 1 0.02 0.5 0.15
88 INT105252 Binding of Rnpep and F2rl1 1 0.01 0 0.15
89 INT180960 Protein_catabolism of COL5A2 Positive_regulation of Positive_regulation of NPEPPS 1 0.00 0.59 0.14
90 INT180963 COL5A2 Positive_regulation of Positive_regulation of NPEPPS 1 0.00 0.59 0.14
91 INT312707 Positive_regulation of DPP4 Positive_regulation of Gene_expression of CD86 1 0.20 0.45 0.13
92 INT117136 NPEPPS Positive_regulation of Hbegf 1 0.00 0 0.12
93 INT106034 PEPD Positive_regulation of Protein_catabolism of COL7A1 1 0.42 0.33 0.12
94 INT118315 Npepo Positive_regulation of Localization of Cck 1 0.48 0.14 0.12
95 INT93745 Binding of Dpp4 and Hephl1 1 0.02 0.15 0.11
96 INT256023 Lnpep Regulation of Gene_expression of Agt 1 0.18 0.14 0.1
97 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 0.06 1.66 0.1
98 INT256022 Lnpep Regulation of Oxt 1 0.15 0.14 0.1
99 INT242204 DPP4 Positive_regulation of Gene_expression of GLP1R 1 0.03 0.66 0.1
100 INT256029 Lnpep Regulation of Agt 1 0.18 0.14 0.1
101 INT280053 Negative_regulation of Dpp4 Negative_regulation of Protein_catabolism of Zglp1 1 0.02 0.71 0.1
102 INT256017 Lnpep Regulation of Avp 1 0.01 0.14 0.1
103 INT111866 Binding of LNPEP and CNOT4 1 0.02 0 0.09
104 INT27051 Trhde Regulation of Negative_regulation of Trh 1 0.17 0 0.09
105 INT111865 Binding of LNPEP and ANGPT4 1 0.06 0 0.09
106 INT194718 DPP4 Positive_regulation of MAPK1 1 0.02 0.29 0.09
107 INT54095 ERAP1 Regulation of Protein_catabolism of Fgg 1 0.00 0 0.09
108 INT294289 IL11 Positive_regulation of Gene_expression of NPEPPS 1 0.01 0.06 0.09
109 INT279435 Positive_regulation of Binding of LTA4H and Lts1 1 0.00 0.16 0.08
110 INT227547 Hspa9 Regulation of Gene_expression of Rnpep 1 0.02 0.31 0.08
111 INT279436 Binding of LTA4H and Lts1 1 0.00 0.16 0.08
112 INT227546 Hspa9 Regulation of Rnpep 1 0.01 0.31 0.08
113 INT351651 Enpep Positive_regulation of Agt 1 0.22 0.93 0.07
114 INT249987 Agt Negative_regulation of Lnpep 1 0.11 0.53 0.07
115 INT36476 C2 Negative_regulation of Positive_regulation of DPP3 1 0.46 0 0.06
116 INT321465 Gip Regulation of DPP4 1 0.03 0.59 0.06
117 INT79523 Binding of HSD11B1 and C9orf3 1 0.52 1.12 0.06
118 INT321466 Glp1r Regulation of DPP4 1 0.04 0.59 0.06
119 INT267923 Negative_regulation of Dpp4 Positive_regulation of Glp1r 1 0.00 0.23 0.05
120 INT321467 Binding of DPP4 and Glp1r 1 0.03 0.42 0.05
121 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05
122 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05
123 INT351652 Enpep Positive_regulation of Positive_regulation of Agt 1 0.19 0.05 0.04
124 INT223425 Binding of Npepo and LOC360919 1 0.00 0 0.03
125 INT336765 Binding of FLT1 and ERAP2 1 0.30 0.58 0.03
126 INT351653 Enpep Positive_regulation of Protein_catabolism of Agt 1 0.22 0.54 0.03
127 INT279538 Binding of C4B and Positive_regulation of ENPEP 1 0.00 0.48 0.03
128 INT223426 Binding of Rnpep and Npepo 1 0.00 0 0.03
129 INT311229 DPP4 Positive_regulation of Gene_expression of INS 1 0.32 0.57 0
130 INT256016 Binding of Oxt and Lnpep 1 0.11 0.64 0
131 INT336764 ERAP2 Regulation of Gene_expression of HLA-E 1 0.24 0 0
132 INT344879 Binding of ENPEP and Mapt 1 0.07 0.08 0
133 INT342358 Binding of Irs1 and Erap1 1 0.37 0 0
134 INT321981 Dpp4 Regulation of Glp1r 1 0.07 1.06 0
135 INT344880 Binding of ANPEP and Mapt 1 0.08 0.15 0
136 INT111860 Negative_regulation of Binding of LNPEP and ANGPT4 1 0.07 0 0
137 INT342367 Binding of Erap1 and OSBPL1A 1 0.39 0 0
138 INT249992 Binding of Lnpep and Igkv4-55 1 0.01 0.47 0
139 INT255024 DPP4 Negative_regulation of Protein_catabolism of GLP1R 1 0.14 0.78 0
140 INT223428 Binding of Cndp2 and Rnpep 1 0.02 0 0
141 INT205393 MME Regulation of Gene_expression of ANPEP 1 0.26 1.49 0
142 INT332634 Dpp4 Positive_regulation of Localization of Ins1 1 0.06 0.76 0
143 INT336780 Ighmbp2 Regulation of ERAP2 1 0.02 0.15 0
144 INT253212 Negative_regulation of Dpp4 Positive_regulation of Localization of INS 1 0.01 0.42 0
145 INT341666 ALPI Positive_regulation of ENPEP 1 0.01 1.05 0
146 INT292135 Binding of Anpep and Rtn4r 1 0.01 0.91 0
147 INT351656 Enpep Regulation of Agt 1 0.20 1.2 0
148 INT70122 NAGLU Positive_regulation of Localization of Anpep 1 0.10 0 0
149 INT253213 Negative_regulation of Dpp4 Positive_regulation of Localization of GCG 1 0.05 0.4 0
150 INT172893 Binding of Lta4h and Ltc4s 1 0.00 0.24 0
151 INT205389 Binding of ANPEP and DCLK1 1 0.09 1.42 0
152 INT321982 Dpp4 Regulation of Gene_expression of Glp1r 1 0.07 1.06 0
153 INT321976 Dpp4 Regulation of Gcg 1 0.13 1.06 0
154 INT159710 Binding of Tap1 and ERAP1 1 0.04 0.11 0
155 INT255041 DPP4 Positive_regulation of GIP 1 0.49 0.32 0
156 INT255021 DPP4 Negative_regulation of Protein_catabolism of GIP 1 0.32 0.78 0
157 INT205392 Binding of ANPEP and PCSK1 1 0.06 1.4 0
158 INT152402 Binding of Il1a and ERAP1 1 0.00 0.06 0
159 INT336762 Negative_regulation of ERAP2 Negative_regulation of HLA-E 1 0.23 0.31 0
160 INT336781 Negative_regulation of ERAP2 Negative_regulation of Atp8a1 1 0.48 0.31 0
161 INT255043 DPP4 Positive_regulation of GLP1R 1 0.35 0.32 0
162 INT205391 MME Regulation of ANPEP 1 0.26 1.36 0
163 INT344878 ENPEP Regulation of Gene_expression of Mapt 1 0.09 0.33 0
164 INT351650 Enpep Regulation of Protein_catabolism of Agt 1 0.20 0.35 0
165 INT253214 Negative_regulation of Dpp4 Negative_regulation of Gene_expression of GCG 1 0.04 0.43 0
166 INT255023 Negative_regulation of DPP4 Positive_regulation of GIP 1 0.35 0.27 0
167 INT279540 Binding of C4B and ENPEP 1 0.00 0.82 0
168 INT344881 ENPEP Regulation of Mapt 1 0.05 0.33 0
169 INT307418 Binding of Cybb and Metap2 1 0.01 0.17 0
170 INT255517 Binding of PHEX and GP6 1 0.05 0.18 0
171 INT331090 Binding of Ctsl and Itga2 1 0.10 0.2 0
172 INT321977 Dpp4 Regulation of Negative_regulation of Gcg 1 0.13 1.06 0
173 INT348644 Binding of DPP4 and GLP1R 1 0.16 0.5 0
174 INT255042 Negative_regulation of DPP4 Positive_regulation of GLP1R 1 0.33 0.34 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for aminopeptidase activity. They are ordered first by their pain relevance and then by number of times they were reported in aminopeptidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT223416 Gene_expression of Trhde 2 0.48 64.16 34.21
2 INT5232 Negative_regulation of Enpep 56 0.57 3.25 26.7
3 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03
4 INT16431 Localization of Lnpep 62 0.70 6.28 23.94
5 INT310853 Positive_regulation of Gene_expression of Trhde 1 0.43 42.95 22.75
6 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53
7 INT13400 Negative_regulation of Enpep 30 0.50 4.23 15.86
8 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25
9 INT7350 Negative_regulation of Anpep 30 0.59 2.89 11.28
10 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51
11 INT18941 Regulation of Enpep 17 0.55 2.56 9.38
12 INT47301 Gene_expression of Ctsl 27 0.76 7.72 9.32
13 INT27050 Positive_regulation of Trhde 2 0.43 14.07 8.23
14 INT10627 Positive_regulation of Lnpep 24 0.69 3.36 7.85
15 INT11441 Negative_regulation of Anpep 18 0.59 3.73 7.51
16 INT81378 Negative_regulation of Dpp4 18 0.59 7.87 7.42
17 INT24504 Localization of Anpep 19 0.80 3.44 6.23
18 INT10624 Regulation of Lnpep 13 0.61 3.27 5.6
19 INT3768 Negative_regulation of ANPEP 16 0.59 4.96 5.52
20 INT33291 Protein_catabolism of Enpep 15 0.85 0.51 5.41
21 INT16432 Positive_regulation of Localization of Lnpep 12 0.32 1.15 5.05
22 INT60066 Positive_regulation of NPEPPS 17 0.22 11.99 4.83
23 INT19967 Gene_expression of C9orf3 18 0.75 26.51 4.6
24 INT19966 Positive_regulation of C9orf3 19 0.67 21.88 4.38
25 INT5332 Negative_regulation of Gene_expression of NPEPPS 11 0.04 7.79 4.29
26 INT9456 Gene_expression of Anpep 9 0.78 1.69 4.26
27 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18
28 INT60067 Localization of NPEPPS 9 0.26 3.36 4.15
29 INT110348 Negative_regulation of Dpp4 28 0.46 22.39 4.12
30 INT47298 Localization of Ctsl 13 0.79 3.77 4.08
31 INT11872 Protein_catabolism of Rnpep 6 0.87 0 4
32 INT188449 Gene_expression of ENPEP 12 0.55 11.29 3.96
33 INT60415 Regulation of NPEPPS 13 0.27 5.81 3.78
34 INT224723 Negative_regulation of Metap2 1 0.33 11.14 3.76
35 INT13451 Positive_regulation of DPP4 23 0.68 9.33 3.62
36 INT39786 Transcription of Lnpep 3 0.69 0.52 3.61
37 INT201959 Positive_regulation of Gene_expression of DPP4 13 0.53 6.24 3.4
38 INT6405 Gene_expression of Enpep 9 0.67 4.79 3.4
39 INT18617 Gene_expression of Npepo 13 0.58 4.78 3.39
40 INT30238 Positive_regulation of Anpep 14 0.66 2.77 3.38
41 INT32340 Negative_regulation of Lnpep 14 0.49 2.63 3.26
42 INT18477 Protein_catabolism of ANPEP 7 0.79 0.41 3.26
43 INT29333 Positive_regulation of Enpep 8 0.70 3.22 3.25
44 INT22492 Binding of Enpep 10 0.47 0.7 3.2
45 INT17673 Negative_regulation of Localization of Lnpep 8 0.09 2.63 3.12
46 INT101034 Protein_catabolism of NPEPPS 8 0.65 2.08 3.12
47 INT5363 Negative_regulation of PEPD 11 0.56 6.49 3.11
48 INT106037 Gene_expression of PEPD 10 0.75 4.18 3.11
49 INT140401 Binding of PEPD 3 0.47 2.22 2.97
50 INT159709 Binding of ERAP1 12 0.47 3.42 2.91
51 INT201952 Binding of DPP4 11 0.37 8.81 2.91
52 INT30228 Protein_catabolism of Anpep 3 0.42 0.82 2.87
53 INT310844 Localization of Trhde 1 0.47 4.78 2.82
54 INT12903 Gene_expression of Lnpep 14 0.71 1.3 2.78
55 INT12051 Negative_regulation of Rnpep 7 0.36 0.42 2.59
56 INT81377 Gene_expression of Dpp4 8 0.71 5.15 2.51
57 INT61805 Positive_regulation of Dpp4 4 0.44 0.41 2.49
58 INT9455 Negative_regulation of Rnpep 5 0.31 0.52 2.47
59 INT16433 Regulation of Localization of Lnpep 6 0.11 0.32 2.45
60 INT24997 Protein_catabolism of Anpep 6 0.96 0 2.34
61 INT31796 Gene_expression of Enpep 5 0.65 0.42 2.32
62 INT10626 Regulation of Positive_regulation of Lnpep 2 0.11 0.1 2.31
63 INT84465 Localization of DPP4 8 0.75 7.28 2.29
64 INT12061 Negative_regulation of LNPEP 19 0.58 5.52 2.14
65 INT18480 Positive_regulation of ANPEP 9 0.59 5.18 2.13
66 INT47303 Regulation of Ctsl 10 0.56 2.64 2.04
67 INT51570 Regulation of Anpep 6 0.43 1.7 2
68 INT161121 Binding of Erap1 2 0.48 1.99 1.99
69 INT310841 Regulation of Gene_expression of Trhde 1 0.28 3.43 1.95
70 INT32677 Positive_regulation of Npepo 8 0.49 3.1 1.92
71 INT58208 Negative_regulation of Ctsl 8 0.53 3.49 1.91
72 INT164270 Gene_expression of Lta4h 4 0.59 3.13 1.84
73 INT5331 Positive_regulation of Gene_expression of NPEPPS 6 0.49 3.74 1.81
74 INT47302 Regulation of Gene_expression of Ctsl 2 0.53 0.54 1.77
75 INT37376 Negative_regulation of Negative_regulation of Enpep 2 0.21 0.07 1.76
76 INT68196 Protein_catabolism of Rnpep 2 0.07 0 1.76
77 INT48357 Positive_regulation of Anpep 7 0.39 2.04 1.75
78 INT30741 Regulation of Npepo 5 0.29 1.42 1.75
79 INT37350 Negative_regulation of ENPEP 7 0.42 1.15 1.7
80 INT104031 Regulation of ENPEP 18 0.33 13.48 1.69
81 INT93744 Binding of Dpp4 4 0.48 0.91 1.61
82 INT79141 Regulation of Gene_expression of NPEPPS 3 0.01 2.95 1.61
83 INT54366 Gene_expression of Anpep 6 0.77 1.38 1.52
84 INT22716 Protein_catabolism of ENPEP 5 0.96 0.1 1.49
85 INT30739 Localization of Npepo 3 0.78 0.63 1.49
86 INT27045 Protein_catabolism of Trhde 2 0.61 2.44 1.46
87 INT30740 Negative_regulation of Regulation of Npepo 2 0.28 0 1.44
88 INT96137 Gene_expression of LNPEP 8 0.68 5.27 1.43
89 INT9454 Gene_expression of Rnpep 5 0.65 0.58 1.43
90 INT34421 Negative_regulation of Npepo 3 0.27 1.28 1.43
91 INT60065 Positive_regulation of Localization of NPEPPS 3 0.22 1.07 1.41
92 INT163354 Negative_regulation of Protein_catabolism of NPEPPS 1 0.25 0 1.4
93 INT84463 Regulation of Gene_expression of DPP4 5 0.39 4.81 1.33
94 INT164274 Transcription of Lta4h 1 0.47 2.09 1.33
95 INT11871 Gene_expression of Rnpep 4 0.23 1.88 1.29
96 INT60064 Negative_regulation of Localization of NPEPPS 3 0.05 0.68 1.27
97 INT37330 Regulation of Binding of Enpep 1 0.27 0 1.26
98 INT7304 Binding of Enpep 3 0.23 0.71 1.22
99 INT201955 Regulation of DPP4 18 0.45 11.91 1.18
100 INT106039 Negative_regulation of Gene_expression of PEPD 5 0.56 1.37 1.18
101 INT35885 Positive_regulation of DPP3 4 0.50 0.1 1.18
102 INT39785 Positive_regulation of Transcription of Lnpep 2 0.50 0.47 1.18
103 INT32786 Localization of Enpep 4 0.68 0 1.16
104 INT35887 Protein_catabolism of DPP3 3 0.85 0 1.14
105 INT279823 Gene_expression of Pepd 1 0.19 2 1.14
106 INT47305 Positive_regulation of Gene_expression of Ctsl 5 0.59 2.06 1.12
107 INT96138 Positive_regulation of LNPEP 6 0.45 3.81 1.07
108 INT15773 Negative_regulation of C9orf3 8 0.57 6.26 1.06
109 INT130814 Binding of ANPEP 8 0.48 4.83 1.05
110 INT27049 Negative_regulation of Trhde 3 0.36 1.65 1.05
111 INT101614 Gene_expression of Dpp4 7 0.78 2.73 1.02
112 INT31314 Positive_regulation of Negative_regulation of Enpep 3 0.35 0.18 1.02
113 INT84325 Regulation of Gene_expression of Anpep 2 0.62 0.06 1.02
114 INT106038 Regulation of PEPD 3 0.43 3.93 1.01
115 INT310839 Transcription of Trhde 1 0.33 2 1
116 INT124615 Transcription of ENPEP 1 0.19 0.2 0.99
117 INT79862 Negative_regulation of Gene_expression of ANPEP 3 0.38 1.67 0.98
118 INT39012 Positive_regulation of Rnpep 3 0.44 0.09 0.98
119 INT106036 Negative_regulation of Negative_regulation of PEPD 2 0.42 0.68 0.98
120 INT226478 Protein_catabolism of DPP4 11 0.85 5.52 0.95
121 INT33664 Negative_regulation of LTA4H 4 0.59 2.34 0.95
122 INT6534 Negative_regulation of Ctsl1 3 0.54 0.11 0.94
123 INT256006 Negative_regulation of Lnpep 1 0.48 2.61 0.9
124 INT114769 Regulation of Enpep 6 0.14 0.58 0.89
125 INT321014 Regulation of Protein_catabolism of Rnpep 1 0.02 0 0.89
126 INT310840 Regulation of Trhde 1 0.28 1.71 0.89
127 INT81206 Binding of ENPEP 11 0.47 5.19 0.88
128 INT79861 Localization of ANPEP 4 0.62 0.54 0.86
129 INT84462 Positive_regulation of Localization of DPP4 2 0.32 1.27 0.85
130 INT42469 Regulation of LNPEP 9 0.60 0.46 0.83
131 INT123089 Negative_regulation of Protein_catabolism of ENPEP 1 0.41 0 0.83
132 INT213960 Localization of Anpep 1 0.09 0.28 0.83
133 INT33097 Negative_regulation of PHEX 3 0.14 0.41 0.82
134 INT36676 Gene_expression of Pepd 2 0.36 1.41 0.82
135 INT10729 Positive_regulation of ENPEP 13 0.38 9.65 0.8
136 INT120046 Negative_regulation of Localization of Ctsl 2 0.40 0.31 0.8
137 INT71530 Positive_regulation of Localization of Npepo 1 0.45 0.5 0.8
138 INT93393 Transcription of Npepo 1 0.29 1.79 0.78
139 INT45645 Negative_regulation of Erap1 2 0.11 0.07 0.77
140 INT45661 Negative_regulation of Protein_catabolism of Enpep 2 0.36 0 0.76
141 INT141115 Negative_regulation of Transcription of Lnpep 1 0.31 0 0.76
142 INT145747 Regulation of ERAP1 1 0.25 0.19 0.76
143 INT77019 Negative_regulation of DPP3 5 0.56 0.35 0.75
144 INT310850 Negative_regulation of Gene_expression of Trhde 1 0.27 1.6 0.75
145 INT310847 Regulation of Positive_regulation of Trhde 1 0.28 1.6 0.75
146 INT105483 Protein_catabolism of LNPEP 3 0.42 3.26 0.74
147 INT61133 Positive_regulation of LTA4H 1 0.49 0 0.74
148 INT25960 Regulation of Dpp4 6 0.32 1.69 0.73
149 INT110349 Regulation of Binding of Dpp4 1 0.26 0 0.72
150 INT92348 Binding of NPEPPS 3 0.04 2.94 0.71
151 INT113893 Protein_catabolism of Dpp4 3 0.57 0.69 0.7
152 INT39013 Negative_regulation of Protein_catabolism of Rnpep 1 0.36 0 0.69
153 INT18479 Negative_regulation of Protein_catabolism of ANPEP 1 0.34 0 0.69
154 INT64223 Regulation of Xpnpep1 3 0.27 3.13 0.68
155 INT310843 Positive_regulation of Positive_regulation of Trhde 1 0.29 0.65 0.68
156 INT19964 Negative_regulation of Positive_regulation of C9orf3 3 0.42 4.06 0.67
157 INT14063 Gene_expression of RNPEP 1 0.04 0 0.66
158 INT310856 Regulation of Localization of Trhde 1 0.28 1.01 0.65
159 INT71532 Regulation of Positive_regulation of Npepo 1 0.26 0.3 0.65
160 INT69283 Gene_expression of PHEX 25 0.75 7.81 0.64
161 INT36675 Negative_regulation of Pepd 3 0.47 8.99 0.63
162 INT60228 Negative_regulation of Negative_regulation of NPEPPS 2 0.34 0.62 0.63
163 INT33579 Positive_regulation of Enpep 4 0.33 5.09 0.58
164 INT154643 Negative_regulation of ERAP1 1 0.11 0.69 0.58
165 INT28687 Gene_expression of Ctsl1 4 0.61 0.48 0.57
166 INT147323 Transcription of Anpep 1 0.42 0.19 0.56
167 INT147321 Negative_regulation of Transcription of Anpep 1 0.34 0.2 0.56
168 INT158678 Positive_regulation of Lta4h 2 0.33 0.55 0.55
169 INT52780 Positive_regulation of Protein_catabolism of Anpep 1 0.17 0 0.55
170 INT35883 Positive_regulation of Protein_catabolism of DPP3 1 0.26 0 0.55
171 INT51843 Localization of Ctsl1 3 0.62 0.54 0.54
172 INT30783 Positive_regulation of Gene_expression of Lnpep 3 0.64 0.66 0.53
173 INT65215 Negative_regulation of Protein_catabolism of Anpep 1 0.36 0 0.53
174 INT142911 Binding of Lnpep 5 0.31 0.36 0.52
175 INT119076 Positive_regulation of PEPD 3 0.63 1.15 0.52
176 INT84880 Regulation of Rnpep 3 0.34 0.15 0.52
177 INT160148 Positive_regulation of Ctsl 2 0.43 0.74 0.52
178 INT138766 Regulation of Pepd 1 0.07 0.18 0.52
179 INT124614 Transcription of ANPEP 3 0.52 1.1 0.51
180 INT141117 Regulation of Transcription of Lnpep 1 0.14 0 0.51
181 INT28507 Regulation of ANPEP 4 0.26 1.84 0.5
182 INT57943 Protein_catabolism of Lnpep 2 0.89 0.09 0.5
183 INT15961 Positive_regulation of Protein_catabolism of Rnpep 1 0.40 0 0.49
184 INT27639 Negative_regulation of Gene_expression of C9orf3 4 0.57 3.97 0.48
185 INT130039 Protein_catabolism of Dpp4 5 0.66 3.03 0.47
186 INT18618 Negative_regulation of Gene_expression of Npepo 1 0.33 0.07 0.47
187 INT120121 Transcription of NPEPPS 2 0.23 0.1 0.46
188 INT36603 Positive_regulation of CTSH 1 0.01 0 0.46
189 INT6533 Binding of Ctsl1 2 0.34 0 0.45
190 INT29334 Positive_regulation of Positive_regulation of Enpep 2 0.47 1.12 0.44
191 INT61867 Positive_regulation of Regulation of Anpep 1 0.36 0.33 0.44
192 INT227518 Positive_regulation of Gene_expression of Dpp4 1 0.34 0 0.44
193 INT54478 Negative_regulation of Positive_regulation of Npepo 1 0.29 0 0.44
194 INT46042 Positive_regulation of Protein_catabolism of Enpep 1 0.28 0 0.43
195 INT61804 Negative_regulation of Positive_regulation of Dpp4 1 0.37 0.24 0.42
196 INT148546 Regulation of Positive_regulation of NPEPPS 1 0.02 0.29 0.42
197 INT69282 Binding of PHEX 4 0.15 1.43 0.41
198 INT15589 Protein_catabolism of PHEX 3 0.21 0.76 0.4
199 INT321021 Positive_regulation of Rnpep 1 0.02 0 0.4
200 INT48356 Binding of Anpep 1 0.32 0 0.4
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