GO:0004364

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Name glutathione transferase activity
Categary Function
Go Slim No
Go Link GO:0004364
Unique Molecular Interactions 111
Total Molecular Interactions 144
Total Single Events 1302
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for glutathione transferase activity. They are ordered first by their pain relevance and then by number of times they were reported for glutathione transferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT347368 RYBP Negative_regulation of GSTK1 1 0.00 0 0.77
2 INT347366 RYBP Regulation of Gene_expression of GSTK1 1 0.00 0 0.57
3 INT347365 RYBP Regulation of GSTK1 1 0.01 0.06 0.47
4 INT108732 Gene_expression of Gstp1 Positive_regulation of Gene_expression of Mgst1 1 0.44 0.58 0.41
5 INT223829 Binding of GSTM1 and GSTP1 2 0.41 2.78 0.39
6 INT56633 Gusb Regulation of Mgst1 1 0.03 0.06 0.24
7 INT56632 Ugt2b17 Regulation of Mgst1 1 0.04 0.06 0.24
8 INT120583 Gsta4 Regulation of Cat 1 0.03 0 0.23
9 INT111313 IL36RN Positive_regulation of Gene_expression of MGST1 1 0.07 0.66 0.22
10 INT223828 Binding of GSTP1 and MAPK8 1 0.06 1.8 0.21
11 INT75039 Slc6a14 Positive_regulation of Gene_expression of Mgst1 1 0.01 0.17 0.17
12 INT352067 Binding of B4GALNT1 and HPGDS 1 0.01 0.12 0.16
13 INT296324 NFE2L2 Regulation of GSTK1 1 0.01 0.91 0.14
14 INT134405 Binding of PTGS1 and HPGDS 1 0.01 0.33 0.14
15 INT335259 Binding of GSTM1 and RA1 1 0.11 0.78 0.13
16 INT171547 IL4 Regulation of GSTK1 1 0.03 0.6 0.12
17 INT79018 Binding of GSTT1 and Gstt1 1 0.27 0.2 0.12
18 INT75029 Gstm1 Regulation of Gene_expression of Gstm2 1 0.00 0.1 0.1
19 INT75032 Gsta2 Regulation of Gene_expression of Gstm2 1 0.00 0.1 0.1
20 INT75035 Gsta2 Regulation of Gene_expression of Gstm1 1 0.00 0.1 0.1
21 INT223827 MAPK8 Positive_regulation of Gene_expression of GSTP1 1 0.12 0.88 0.1
22 INT75027 Gstm1 Regulation of Gene_expression of Gsta2 1 0.00 0.1 0.1
23 INT164428 Gsta3 Positive_regulation of Npr1 1 0.00 0 0.1
24 INT153696 Binding of GSTM1 and Gstt1 1 0.06 0.71 0.08
25 INT278164 GSTM1 Positive_regulation of Transcription of GSTP1 1 0.57 0.94 0.07
26 INT231120 GYPA Positive_regulation of Gene_expression of GSTM1 1 0.05 0.15 0.07
27 INT166919 Binding of CAT and GSTK1 1 0.09 0.16 0.07
28 INT270983 Binding of Cpe and GSTK1 1 0.01 0.12 0.07
29 INT192309 Binding of GSTM1 and GSTT1 2 0.43 4.54 0.06
30 INT223825 GSTP1 Negative_regulation of MAPK8 1 0.11 1.53 0.06
31 INT307157 Berr1 Regulation of Mgst1 1 0.00 1.51 0.05
32 INT223826 GSTM1 Negative_regulation of MAP3K5 1 0.02 0.71 0.03
33 INT223824 Binding of GSTM1 and MAP3K5 1 0.02 0.68 0.03
34 INT321178 Binding of Ntrk2 and Mgst1 1 0.07 0 0.03
35 INT270985 Binding of Slc6a3 and GSTK1 1 0.02 0.05 0.03
36 INT297159 Gsta3 Negative_regulation of Hif1a 1 0.00 0.54 0.03
37 INT182946 Binding of PELP1 and GSTK1 1 0.03 0.13 0
38 INT290811 Binding of Mgst1 and Gsk3b 1 0.05 0 0
39 INT351834 Binding of Gmcl1 and GSTK1 1 0.03 0.42 0
40 INT269937 Binding of Smad3 and Mgst1 1 0.09 0 0
41 INT280969 Binding of Cav3 and Mgst1 1 0.01 0 0
42 INT269928 Binding of Sox17 and Mgst1 1 0.12 0 0
43 INT285389 Binding of Ppara and Mgst1 1 0.11 0.22 0
44 INT257666 Binding of Mgst1 and Pard3 1 0.05 0 0
45 INT330735 GSTK1 Regulation of HMOX1 1 0.08 0.25 0
46 INT283002 Binding of Bak1 and Mgst1 1 0.01 0.24 0
47 INT197552 GSTK1 Positive_regulation of NQO1 1 0.09 1.06 0
48 INT352064 Binding of PTGS2 and HPGDS 1 0.20 0 0
49 INT244349 Binding of GSTM1 and GSTK1 1 0.35 1.22 0
50 INT334491 Binding of GCN1L1 and Mgst1 1 0.08 0 0
51 INT217922 Binding of GSTA4 and SULT1D1P 1 0.29 0 0
52 INT159977 Binding of Mgst1 and Gnat3 1 0.03 0 0
53 INT229863 Fos Positive_regulation of GSTK1 1 0.03 0.37 0
54 INT65902 GSTK1 Regulation of Positive_regulation of Gnat3 1 0.02 0 0
55 INT317766 Nfe2l2 Regulation of Gstm1 1 0.11 0 0
56 INT246533 Fdft1 Positive_regulation of Gene_expression of Gstp2 1 0.01 1.57 0
57 INT217923 Positive_regulation of Binding of GSTA4 and SULT1D1P 1 0.37 0 0
58 INT182933 Binding of NCOA2 and GSTK1 1 0.01 0.08 0
59 INT291419 Binding of GSTM1 and Gopc 1 0.03 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for glutathione transferase activity. They are ordered first by their pain relevance and then by number of times they were reported in glutathione transferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81
2 INT55091 Positive_regulation of Mgst1 35 0.69 10.77 6.88
3 INT51137 Negative_regulation of GSTM1 39 0.43 14.74 6.5
4 INT69561 Positive_regulation of GSTM1 23 0.50 5.69 6.36
5 INT31598 Gene_expression of Mgst1 41 0.78 6.44 6.3
6 INT29561 Binding of GSTM1 35 0.48 25.86 6.24
7 INT59891 Positive_regulation of GSTK1 46 0.67 17.66 5.33
8 INT86219 Negative_regulation of GSTK1 25 0.41 8.99 4.97
9 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2
10 INT60541 Regulation of GSTK1 12 0.61 6.76 3.31
11 INT134413 Gene_expression of HPGDS 20 0.77 8.93 3.28
12 INT255307 Phosphorylation of Mgst1 5 0.14 0.12 3.05
13 INT55629 Regulation of Mgst1 12 0.53 2.7 2.62
14 INT75004 Regulation of Gene_expression of Mgst1 3 0.61 0.72 2.44
15 INT92075 Regulation of GSTM1 12 0.50 16.18 2.27
16 INT89166 Transcription of Mgst1 6 0.72 2 2.27
17 INT22342 Gene_expression of Gstp2 5 0.38 3.98 1.86
18 INT135077 Binding of GSTP1 11 0.48 7.03 1.8
19 INT31599 Negative_regulation of Mgst1 14 0.59 5.35 1.72
20 INT78202 Binding of GSTK1 17 0.31 5.44 1.66
21 INT29560 Negative_regulation of Binding of GSTM1 4 0.42 1.21 1.59
22 INT347374 Regulation of Transcription of GSTK1 1 0.08 0.82 1.58
23 INT89167 Positive_regulation of Gene_expression of Mgst1 11 0.69 2.09 1.53
24 INT60571 Positive_regulation of Gsta4 8 0.45 3.76 1.44
25 INT347375 Transcription of GSTK1 1 0.13 0.8 1.44
26 INT75013 Positive_regulation of Gsta2 5 0.39 1.36 1.3
27 INT79927 Localization of GSTK1 5 0.40 1.29 1.21
28 INT68359 Positive_regulation of HPGDS 9 0.32 4.63 1.18
29 INT60542 Positive_regulation of Gene_expression of GSTK1 11 0.39 6.21 1.13
30 INT89164 Positive_regulation of Transcription of Mgst1 4 0.60 1.53 1.13
31 INT57708 Negative_regulation of Gstp2 1 0.37 0 1.11
32 INT57709 Positive_regulation of Gstp2 2 0.60 0.87 1.1
33 INT59575 Gene_expression of MGST1 2 0.52 3.47 0.98
34 INT79017 Gene_expression of GSTT1 23 0.73 13.16 0.97
35 INT75019 Gene_expression of Gsta2 5 0.65 2.01 0.84
36 INT77357 Regulation of Gstt1 2 0.50 0.8 0.83
37 INT77359 Positive_regulation of Gstt1 3 0.56 0.33 0.78
38 INT54771 Regulation of Gstp2 1 0.06 0 0.78
39 INT79016 Gene_expression of Gstt1 4 0.44 0.59 0.7
40 INT264537 Transcription of HPGDS 1 0.33 1.33 0.69
41 INT129006 Negative_regulation of Gstp1 1 0.34 1.85 0.65
42 INT117683 Positive_regulation of Gene_expression of GSTM1 4 0.50 1.31 0.58
43 INT68360 Regulation of HPGDS 3 0.23 0.72 0.56
44 INT106022 Negative_regulation of GSTP1 5 0.59 2.12 0.55
45 INT177864 Negative_regulation of HPGDS 6 0.49 1.92 0.54
46 INT59576 Positive_regulation of Gene_expression of MGST1 2 0.34 2.07 0.54
47 INT120762 Regulation of GSTP1 2 0.45 3.66 0.54
48 INT55628 Negative_regulation of Regulation of Mgst1 1 0.43 0 0.51
49 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48
50 INT78460 Negative_regulation of Positive_regulation of Mgst1 1 0.43 0.39 0.47
51 INT75024 Positive_regulation of Gstm1 4 0.31 0.49 0.46
52 INT121341 Transcription of GSTM1 3 0.69 2.21 0.44
53 INT134412 Binding of HPGDS 9 0.42 1.7 0.43
54 INT20056 Positive_regulation of MGST1 2 0.47 0.7 0.42
55 INT183373 Positive_regulation of Gene_expression of Gstp2 2 0.34 4.17 0.4
56 INT325423 Localization of Gstp1 1 0.06 0.85 0.37
57 INT325425 Positive_regulation of Localization of Gstp1 1 0.04 0.9 0.37
58 INT110955 Negative_regulation of Gene_expression of GSTM1 1 0.42 0.41 0.36
59 INT110954 Negative_regulation of Gene_expression of GSTT1 1 0.41 0.41 0.36
60 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35
61 INT111315 Regulation of Gene_expression of MGST1 1 0.42 1.04 0.34
62 INT137665 Regulation of Gsta3 1 0.28 0.17 0.34
63 INT144474 Protein_catabolism of Gstp1 1 0.06 0.57 0.33
64 INT199762 Positive_regulation of Gstp1 2 0.55 2.02 0.32
65 INT75006 Gene_expression of Gstm1 6 0.45 2.19 0.29
66 INT278169 Regulation of Regulation of GSTP1 1 0.45 1.1 0.25
67 INT278172 Regulation of Regulation of GSTM1 1 0.45 1.1 0.25
68 INT132595 Binding of Gstt1 2 0.13 1.78 0.24
69 INT264539 Localization of HPGDS 1 0.46 0.48 0.24
70 INT117253 Regulation of Gene_expression of GSTT1 1 0.45 0.6 0.2
71 INT127750 Positive_regulation of Positive_regulation of GSTM1 1 0.19 0 0.2
72 INT350864 Negative_regulation of Gene_expression of HPGDS 1 0.36 0.52 0.2
73 INT120761 Positive_regulation of GSTP1 3 0.50 3.4 0.19
74 INT350865 Negative_regulation of Binding of HPGDS 1 0.36 0.51 0.19
75 INT117252 Regulation of GSTT1 3 0.45 12.44 0.18
76 INT75009 Regulation of Gstm2 1 0.00 0.18 0.17
77 INT75003 Positive_regulation of Positive_regulation of Mgst1 1 0.08 0.18 0.17
78 INT58629 Negative_regulation of Gsta4 1 0.44 0.33 0.16
79 INT255303 Localization of Mgst1 6 0.27 0.9 0.15
80 INT159975 Positive_regulation of Gene_expression of Mgst1 1 0.45 0.14 0.14
81 INT159974 Gene_expression of Mgst1 1 0.50 0.14 0.14
82 INT190608 Gene_expression of Gstm1 2 0.62 1.92 0.13
83 INT278170 Positive_regulation of Transcription of GSTM1 1 0.50 1.86 0.13
84 INT278171 Positive_regulation of Transcription of GSTP1 1 0.50 1.86 0.13
85 INT314340 Positive_regulation of Localization of Mgst1 1 0.04 0.82 0.13
86 INT192311 Binding of GSTT1 7 0.48 10.62 0.12
87 INT218018 Regulation of Gene_expression of GSTK1 5 0.37 2.74 0.11
88 INT79015 Negative_regulation of Gstt1 3 0.39 0.24 0.11
89 INT155805 Negative_regulation of Negative_regulation of Mgst1 1 0.41 0.47 0.11
90 INT251898 Negative_regulation of Transcription of Gsta4 1 0.08 1.04 0.11
91 INT223834 Localization of GSTP1 2 0.70 1.28 0.1
92 INT251899 Transcription of Gsta4 1 0.10 1.04 0.1
93 INT128299 Protein_catabolism of Gsta3 1 0.97 0 0.1
94 INT59572 Localization of MGST1 1 0.19 0.16 0.1
95 INT75008 Gene_expression of Gstm2 1 0.00 0.1 0.1
96 INT120767 Negative_regulation of Gene_expression of GSTP1 3 0.42 1.15 0.09
97 INT246529 Localization of Gstp2 3 0.41 3.63 0.09
98 INT120771 Negative_regulation of Positive_regulation of GSTP1 1 0.30 0.39 0.08
99 INT120766 Regulation of Positive_regulation of GSTP1 1 0.32 0.39 0.08
100 INT270644 Binding of Gstm1 1 0.33 1.43 0.07
101 INT278173 Transcription of GSTP1 1 0.68 0.93 0.07
102 INT341823 Regulation of Gstm1 1 0.00 0.36 0.06
103 INT321165 Positive_regulation of Phosphorylation of Mgst1 1 0.12 0.13 0.06
104 INT199794 Regulation of Gene_expression of GSTM1 4 0.31 1.92 0.05
105 INT299542 Phosphorylation of GSTK1 2 0.34 0.19 0.05
106 INT159973 Positive_regulation of Positive_regulation of Mgst1 1 0.33 0.05 0.05
107 INT159976 Positive_regulation of Mgst1 1 0.33 0.05 0.05
108 INT207902 Binding of Mgst1 19 0.18 0.93 0.04
109 INT99629 Localization of GSTM1 8 0.80 6.72 0.04
110 INT191414 Negative_regulation of Gene_expression of GSTK1 4 0.13 1.3 0.04
111 INT217650 Protein_catabolism of GSTK1 1 0.06 0.48 0.04
112 INT202207 Negative_regulation of Binding of GSTT1 2 0.42 0.77 0.03
113 INT206502 Positive_regulation of Positive_regulation of GSTK1 1 0.07 0.93 0.03
114 INT202203 Positive_regulation of GSTT1 4 0.47 1.26 0
115 INT203874 Positive_regulation of Gene_expression of GSTP1 3 0.49 1.91 0
116 INT202208 Localization of GSTT1 3 0.74 3.91 0
117 INT203875 Phosphorylation of GSTM1 2 0.81 1.27 0
118 INT146662 Positive_regulation of Gene_expression of Gsta2 1 0.26 0 0
119 INT299543 Positive_regulation of Localization of GSTK1 1 0.04 0.31 0
120 INT299544 Negative_regulation of Phosphorylation of GSTK1 1 0.03 0.19 0
121 INT244365 Regulation of Binding of GSTT1 1 0.61 4.62 0
122 INT291418 Regulation of Protein_catabolism of GSTM1 1 0.04 0.22 0
123 INT271824 Negative_regulation of Negative_regulation of Gstm1 1 0.29 0.93 0
124 INT305470 Regulation of Gene_expression of GSTP1 1 0.06 0.59 0
125 INT203877 Phosphorylation of GSTP1 1 0.79 0.22 0
126 INT271819 Negative_regulation of Gene_expression of Gstm1 1 0.34 0.99 0
127 INT207900 Negative_regulation of Gene_expression of Mgst1 1 0.20 0.09 0
128 INT244360 Regulation of Transcription of GSTM1 1 0.45 1.29 0
129 INT269912 Positive_regulation of Binding of Mgst1 1 0.14 0 0
130 INT199764 Positive_regulation of Gene_expression of Gstp1 1 0.55 2.21 0
131 INT271816 Regulation of Gstm1 1 0.30 1.86 0
132 INT291417 Protein_catabolism of GSTM1 1 0.09 0.22 0
133 INT244357 Regulation of Binding of GSTM1 1 0.62 1.9 0
134 INT244361 Regulation of Transcription of GSTT1 1 0.45 1.29 0
135 INT79014 Positive_regulation of Gene_expression of Gstt1 1 0.31 0 0
136 INT244363 Transcription of GSTT1 1 0.68 1.23 0
137 INT271826 Negative_regulation of Gstm1 1 0.29 0.93 0
138 INT203870 Negative_regulation of Binding of GSTP1 1 0.42 0.22 0
139 INT289111 Positive_regulation of Negative_regulation of GSTK1 1 0.04 0.76 0
140 INT203876 Positive_regulation of Gene_expression of GSTT1 1 0.50 0.18 0
141 INT203878 Phosphorylation of GSTT1 1 0.80 0.22 0
142 INT206503 Negative_regulation of GSTT1 1 0.34 0.97 0
143 INT244359 Positive_regulation of Binding of GSTM1 1 0.50 2.45 0
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