GO:0004445

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Name inositol-polyphosphate 5-phosphatase activity
Categary Function
Go Slim No
Go Link GO:0004445
Unique Molecular Interactions 25
Total Molecular Interactions 28
Total Single Events 106
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for inositol-polyphosphate 5-phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported for inositol-polyphosphate 5-phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT301079 Binding of GNAT1 and INPP5E 1 0.00 0.59 0.89
2 INT299113 Binding of INPP5K and GOPC 1 0.18 2.69 0.19
3 INT67619 Inpp5k Negative_regulation of Ptgs1 1 0.03 0.5 0.13
4 INT312218 INPP5K Positive_regulation of Protein_catabolism of IGFBP3 1 0.17 0.39 0.11
5 INT312212 Binding of ADAM12 and INPP5K 1 0.16 0.46 0.11
6 INT347647 Inpp5d Negative_regulation of Pik3r1 1 0.31 0.37 0.1
7 INT218857 INPP5E Regulation of ATP12A 1 0.01 1.95 0.09
8 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
9 INT312226 INPP5K Positive_regulation of IGFBP5 1 0.12 0.07 0.05
10 INT322876 Binding of PDCD10 and Inpp5d 1 0.03 0.46 0.03
11 INT234978 Binding of Dsg3 and Positive_regulation of Inppl1 1 0.00 0.32 0.03
12 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
13 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
14 INT312220 IL4 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
15 INT312222 IFNA1 Positive_regulation of Regulation of INPP5K 1 0.05 0.24 0
16 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
17 INT312225 Positive_regulation of INPP5K Positive_regulation of CD44 1 0.15 0.1 0
18 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
19 INT312223 INPP5K Negative_regulation of Gene_expression of COL10A1 1 0.04 0.1 0
20 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
21 INT312215 INPP5K Negative_regulation of COL10A1 1 0.03 0.1 0
22 INT312229 INPP5K Positive_regulation of CD44 1 0.15 0.1 0
23 INT312216 INPP5K Negative_regulation of Gene_expression of RUNX2 1 0.15 0.1 0
24 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
25 INT312217 Binding of INS and INPP5K 1 0.03 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for inositol-polyphosphate 5-phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported in inositol-polyphosphate 5-phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15157 Gene_expression of INPP5K 30 0.67 15.49 2.85
2 INT142496 Regulation of INPP5E 2 0.42 0.7 2.66
3 INT67618 Positive_regulation of Inpp5k 3 0.45 0.77 2.64
4 INT141455 Negative_regulation of Inpp5k 2 0.36 1.09 1.51
5 INT125296 Regulation of Inpp5k 1 0.22 0 1.32
6 INT78330 Positive_regulation of INPP5E 3 0.32 0.19 1.22
7 INT143846 Positive_regulation of INPP5K 5 0.40 6.4 1.17
8 INT131421 Localization of INPP5K 9 0.74 4.3 0.59
9 INT299115 Regulation of INPP5K 6 0.39 4.11 0.59
10 INT330616 Positive_regulation of Gene_expression of Inpp5d 2 0.49 0.89 0.34
11 INT132881 Binding of INPP5K 7 0.48 4.35 0.33
12 INT119907 Binding of Inpp5k 3 0.33 0.6 0.32
13 INT330615 Gene_expression of Inpp5d 2 0.66 0.78 0.31
14 INT323982 Gene_expression of INPP5E 1 0.04 2.27 0.27
15 INT173164 Negative_regulation of INPP5K 4 0.51 2.01 0.24
16 INT330612 Positive_regulation of Localization of Inpp5d 1 0.02 0.35 0.22
17 INT330610 Localization of Inpp5d 1 0.02 0.3 0.22
18 INT347641 Regulation of Positive_regulation of Inpp5d 1 0.27 0.33 0.19
19 INT347643 Positive_regulation of Inpp5d 1 0.46 0.33 0.18
20 INT214926 Negative_regulation of INPP5E 5 0.03 3.93 0.09
21 INT299116 Regulation of Gene_expression of INPP5K 1 0.39 1.13 0.06
22 INT322923 Positive_regulation of Positive_regulation of INPP5K 1 0.39 1.51 0.06
23 INT317422 Binding of INPP5E 1 0.01 0.8 0.04
24 INT285357 Positive_regulation of Gene_expression of Inpp5k 1 0.16 0.17 0.03
25 INT285359 Gene_expression of Inpp5k 1 0.22 0.17 0.03
26 INT350662 Regulation of Inpp5d 1 0.06 0.16 0
27 INT330881 Regulation of Inppl1 1 0.13 0 0
28 INT323981 Positive_regulation of Gene_expression of INPP5E 1 0.03 0.96 0
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