GO:0004467

From wiki-pain
Jump to: navigation, search
Name long-chain fatty acid-CoA ligase activity
Categary Function
Go Slim No
Go Link GO:0004467
Unique Molecular Interactions 45
Total Molecular Interactions 56
Total Single Events 366
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for long-chain fatty acid-CoA ligase activity. They are ordered first by their pain relevance and then by number of times they were reported for long-chain fatty acid-CoA ligase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT311466 Binding of Acsl1 and Il1 1 0.00 2.46 0.63
2 INT311467 Binding of Crp and Acsl1 1 0.00 2.31 0.61
3 INT116268 Binding of Myc and Acsl1 1 0.08 0.19 0.16
4 INT301638 Ppara Regulation of Slc27a2 1 0.30 0.29 0.14
5 INT301645 Binding of Alb and Slc27a1 1 0.02 0.38 0.08
6 INT301614 Binding of Slc27a1 and Cd36 1 0.09 0.38 0.08
7 INT343157 ACSL4 Regulation of Gene_expression of ALOX15 1 0.01 0.67 0.07
8 INT301623 Ins1 Positive_regulation of Slc27a2 1 0.01 0.37 0.07
9 INT301658 Ins1 Positive_regulation of Slc27a4 1 0.01 0.37 0.07
10 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05
11 INT200889 Acsl1 Positive_regulation of Mapk14 1 0.01 0.09 0.05
12 INT298734 USE1 Regulation of ACSBG1 1 0.00 0.97 0.05
13 INT335052 PPARA Positive_regulation of Gene_expression of ACSL1 1 0.51 0.06 0.05
14 INT200890 Acsl1 Positive_regulation of Mapk1 1 0.03 0.09 0.05
15 INT335133 PPARA Positive_regulation of Slc27a1 1 0.10 0.14 0.04
16 INT335127 PPARA Regulation of Slc27a1 1 0.13 0.13 0.04
17 INT343164 ACSL4 Regulation of Positive_regulation of ALOX15 1 0.01 1.08 0.03
18 INT225485 Binding of Acsl1 and Ncoa6 1 0.01 0 0
19 INT225479 Binding of Parp1 and Acsl1 1 0.00 0 0
20 INT225480 Binding of Prkdc and Acsl1 1 0.00 0 0
21 INT343158 ACSL4 Regulation of Regulation of ALOX15 1 0.01 0.47 0
22 INT225486 Rbm39 Positive_regulation of Acsl1 1 0.00 0 0
23 INT225642 Binding of XRCC5 and Acsl1 1 0.01 0 0
24 INT301636 Slc27a1 Positive_regulation of Fabp4 1 0.01 0 0
25 INT343163 ACSL4 Regulation of Gene_expression of PTGS2 1 0.08 0.5 0
26 INT225483 Binding of Acsl1 and D0Nrs1 1 0.00 0 0
27 INT225643 Binding of TARBP2 and Acsl1 1 0.00 0 0
28 INT225487 Acsl1 Positive_regulation of D0Nrs1 1 0.00 0 0
29 INT343155 ACSL4 Regulation of CPOX 1 0.01 1.03 0
30 INT343162 ACSL4 Regulation of LOX 1 0.03 1.04 0
31 INT343161 ACSL4 Regulation of Gene_expression of TSPO 1 0.25 0.75 0
32 INT343159 ACSL4 Regulation of Gene_expression of LOX 1 0.07 1.04 0
33 INT227796 Binding of Acsl1 and Nos3 1 0.16 1.16 0
34 INT301624 Slc27a1 Positive_regulation of fa 1 0.03 0 0
35 INT343160 ACSL4 Regulation of Positive_regulation of ALOX5 1 0.02 0.32 0
36 INT301654 Binding of Slc27a2 and Slc27a5 1 0.15 0.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for long-chain fatty acid-CoA ligase activity. They are ordered first by their pain relevance and then by number of times they were reported in long-chain fatty acid-CoA ligase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75869 Gene_expression of Acsl1 24 0.45 27.76 3.66
2 INT86184 Negative_regulation of Acsl1 10 0.34 20.45 2.23
3 INT87100 Gene_expression of ACSL1 10 0.58 1.56 1.62
4 INT96694 Negative_regulation of Slc27a5 1 0.53 0.96 1.3
5 INT55619 Binding of Acsl1 8 0.31 9.91 1.22
6 INT20470 Positive_regulation of Acsl1 5 0.40 3.76 1.03
7 INT170742 Positive_regulation of Acsl1 6 0.44 6.98 0.86
8 INT311464 Negative_regulation of Binding of Acsl1 1 0.03 2.71 0.83
9 INT190781 Binding of Acsl1 6 0.36 9.12 0.76
10 INT230901 Regulation of Acsl1 2 0.03 1.65 0.75
11 INT114608 Negative_regulation of Transcription of Acsl1 1 0.27 0.48 0.75
12 INT114609 Transcription of Acsl1 1 0.45 0.47 0.74
13 INT337755 Protein_catabolism of Acsl1 1 0.21 0.72 0.65
14 INT301579 Gene_expression of Slc27a2 1 0.38 1.86 0.63
15 INT170739 Gene_expression of Acsl1 8 0.65 7.02 0.5
16 INT301558 Positive_regulation of Gene_expression of Slc27a2 1 0.34 1.28 0.39
17 INT170737 Localization of Acsl1 5 0.20 3.51 0.38
18 INT147014 Localization of Acsl1 3 0.60 2.35 0.36
19 INT311465 Positive_regulation of Localization of Acsl1 1 0.04 1.63 0.36
20 INT343192 Gene_expression of ACSL4 1 0.75 20.21 0.35
21 INT127469 Negative_regulation of Gene_expression of ACSL1 1 0.18 0 0.25
22 INT127470 Positive_regulation of Gene_expression of ACSL1 1 0.22 0 0.25
23 INT343200 Binding of ACSL4 1 0.36 3.32 0.23
24 INT227795 Negative_regulation of Acsl1 3 0.21 3.05 0.21
25 INT311462 Positive_regulation of Gene_expression of Acsl1 1 0.04 2.13 0.2
26 INT235268 Positive_regulation of Gene_expression of Acsl1 2 0.49 1.96 0.17
27 INT301591 Positive_regulation of Slc27a2 1 0.34 1.44 0.17
28 INT116264 Negative_regulation of Gene_expression of Acsl1 1 0.20 0.2 0.17
29 INT227794 Regulation of Acsl1 4 0.26 3.25 0.14
30 INT343185 Positive_regulation of ACSL4 1 0.48 4.56 0.13
31 INT343182 Positive_regulation of Gene_expression of ACSL4 1 0.67 5.04 0.12
32 INT343188 Negative_regulation of Gene_expression of ACSL4 1 0.56 3.46 0.1
33 INT298737 Regulation of ACSBG1 1 0.00 2.06 0.08
34 INT343198 Positive_regulation of Binding of ACSL4 1 0.48 0.66 0.08
35 INT301544 Gene_expression of Slc27a5 1 0.58 0.5 0.07
36 INT301536 Gene_expression of Slc27a4 1 0.22 0.5 0.07
37 INT301531 Positive_regulation of Slc27a4 1 0.14 0.58 0.07
38 INT301555 Gene_expression of Slc27a1 3 0.26 0.45 0.04
39 INT343178 Negative_regulation of Positive_regulation of ACSL4 1 0.41 0.92 0.04
40 INT343183 Negative_regulation of ACSL4 1 0.42 1.45 0.04
41 INT301580 Positive_regulation of Gene_expression of Slc27a1 1 0.15 0.23 0
42 INT298738 Binding of ACSBG1 1 0.01 0.74 0
43 INT301585 Localization of Slc27a2 1 0.40 0.12 0
44 INT301576 Binding of Slc27a5 1 0.28 0.06 0
45 INT301562 Regulation of Slc27a4 1 0.08 0.22 0
46 INT332021 Negative_regulation of Phosphorylation of Acsl1 1 0.41 0 0
47 INT343177 Regulation of Regulation of ACSL4 1 0.26 0.12 0
48 INT301535 Positive_regulation of Gene_expression of Slc27a4 1 0.14 0.46 0
49 INT298735 Negative_regulation of ACSBG1 1 0.01 0.65 0
50 INT312970 Negative_regulation of ACSL1 1 0.01 0.56 0
51 INT301522 Positive_regulation of Gene_expression of Slc27a5 1 0.38 0.46 0
52 INT301584 Binding of Slc27a1 1 0.10 0.07 0
53 INT298736 Positive_regulation of ACSBG1 1 0.01 1.29 0
54 INT301571 Regulation of Slc27a2 1 0.13 0.22 0
55 INT332022 Phosphorylation of Acsl1 1 0.79 0 0
56 INT188615 Positive_regulation of ACSL1 1 0.00 0 0
57 INT343195 Transcription of ACSL4 1 0.51 0.58 0
58 INT343189 Regulation of Gene_expression of ACSL4 1 0.59 1.49 0
59 INT343181 Regulation of ACSL4 1 0.59 1.26 0
60 INT336750 Regulation of Gene_expression of Acsl1 1 0.05 0.4 0
61 INT301547 Positive_regulation of Slc27a5 1 0.15 0.23 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox