GO:0004468

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Name lysine N-acetyltransferase activity
Categary Function
Go Slim No
Go Link GO:0004468
Unique Molecular Interactions 33
Total Molecular Interactions 40
Total Single Events 137
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for lysine N-acetyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported for lysine N-acetyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
2 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
3 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
4 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
5 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
6 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
7 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
8 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
9 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
10 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
11 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
12 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
13 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
14 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
15 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
16 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
17 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
18 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
19 INT225562 Binding of Srcs4 and Ep300 1 0.02 0 0
20 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0
21 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
22 INT172604 Binding of EP300 and TP53 1 0.00 0 0
23 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
24 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
25 INT225619 Binding of TARBP2 and Ep300 1 0.02 0 0
26 INT172605 Positive_regulation of Binding of EP300 and TP53 1 0.00 0 0
27 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0
28 INT225543 Binding of D0Nrs1 and Ep300 1 0.01 0 0
29 INT225563 Binding of Tpr and Ep300 1 0.00 0 0
30 INT225622 Binding of STL and Ep300 1 0.01 0 0
31 INT225587 Binding of Kat2b and Cytip 1 0.12 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for lysine N-acetyltransferase activity. They are ordered first by their pain relevance and then by number of times they were reported in lysine N-acetyltransferase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
2 INT2213 Regulation of EP300 10 0.54 4.72 4.5
3 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
4 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
5 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
6 INT171514 Binding of EP300 13 0.32 4.32 2.01
7 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
8 INT172622 Localization of EP300 8 0.65 2.56 1.72
9 INT54996 Regulation of KAT2B 1 0.19 0.38 1.45
10 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
11 INT167650 Binding of Ep300 1 0.09 0.14 1
12 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
13 INT239084 Localization of KAT2B 4 0.73 3.08 0.36
14 INT187587 Binding of Ep300 11 0.35 2.37 0.34
15 INT266973 Negative_regulation of KAT2B 1 0.01 0.99 0.29
16 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
17 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
18 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
19 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
20 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
21 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
22 INT101082 Positive_regulation of KAT2B 1 0.38 0.76 0.09
23 INT239085 Binding of KAT2B 1 0.18 2.04 0.09
24 INT292252 Phosphorylation of EP300 1 0.20 0.55 0.05
25 INT235154 Transcription of Ep300 2 0.24 1.38 0
26 INT222914 Negative_regulation of Gene_expression of EP300 1 0.02 0.05 0
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