GO:0004505

From wiki-pain
Jump to: navigation, search
Name phenylalanine 4-monooxygenase activity
Categary Function
Go Slim No
Go Link GO:0004505
Unique Molecular Interactions 88
Total Molecular Interactions 124
Total Single Events 923
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phenylalanine 4-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for phenylalanine 4-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61687 Binding of Pah and Slc3a1 1 0.00 0.11 1.09
2 INT188318 MCPH1 Positive_regulation of Pah 3 0.02 3 0.85
3 INT45822 Pah Positive_regulation of Localization of Ins1 1 0.01 0.3 0.73
4 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
5 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
6 INT43587 Binding of OPRD1 and Pah 1 0.00 0.08 0.43
7 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38
8 INT261597 Binding of PAH and COPD 1 0.00 1.08 0.34
9 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
10 INT146248 Pcbd1 Positive_regulation of Trpv1 1 0.02 0 0.31
11 INT146247 Pcbd1 Positive_regulation of Trpa1 1 0.02 0 0.31
12 INT261609 Binding of PAH and Hypt 1 0.00 1.26 0.28
13 INT283373 Pcbd1 Regulation of RYR1 1 0.00 1.45 0.21
14 INT284142 ERAS Regulation of PAH 1 0.10 0.55 0.2
15 INT192109 PAH Positive_regulation of Binding of COL7A1 1 0.04 1.45 0.2
16 INT284138 ERAS Regulation of Positive_regulation of PAH 1 0.10 0.55 0.2
17 INT160515 Negative_regulation of Sert1 Negative_regulation of Pah 1 0.34 0.84 0.19
18 INT47164 Binding of Asap1 and Pah 1 0.27 0.07 0.17
19 INT303028 Binding of Pah and MCPH1 1 0.02 1.13 0.16
20 INT303003 Gene_expression of Ptgis Positive_regulation of Pah 1 0.36 1.67 0.13
21 INT303007 Binding of Pah and Ptgis 1 0.26 0.99 0.12
22 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
23 INT200213 PAH Positive_regulation of SDHD 1 0.21 2.43 0.1
24 INT284140 Binding of EDNRB and PAH 1 0.08 0.1 0.1
25 INT249925 Cpox Negative_regulation of Pah 1 0.01 0.18 0.1
26 INT284141 Binding of EDNRA and PAH 1 0.05 0.1 0.09
27 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
28 INT189550 Binding of BMPR2 and PAH 1 0.06 2.68 0.08
29 INT273616 PVR Positive_regulation of Pah 1 0.10 0.86 0.07
30 INT303027 Gene_expression of MCPH1 Positive_regulation of Pah 1 0.02 0.83 0.07
31 INT249922 Binding of Pah and Asph 1 0.06 0.4 0.04
32 INT343719 Nlrp1a Positive_regulation of PAH 1 0.00 1.9 0.04
33 INT303008 Gene_expression of Pah Positive_regulation of Gene_expression of Ptgis 1 0.31 0.78 0.04
34 INT170910 Negative_regulation of Pcbd1 Positive_regulation of Positive_regulation of Mapk8 1 0.00 0.21 0.03
35 INT127464 Binding of PAH and Slc6a4 1 0.08 0 0
36 INT313871 Pde5a Positive_regulation of Pah 1 0.49 0.97 0
37 INT100424 Bcl2 Regulation of Pcbd1 1 0.14 0.06 0
38 INT283372 Binding of RYR1 and Pcbd1 1 0.00 0.28 0
39 INT309846 Binding of pad and Pah 1 0.03 0.98 0
40 INT317602 Binding of TNC and PAH 1 0.02 1.74 0
41 INT242340 Binding of COL7A1 and PAH 1 0.00 1.35 0
42 INT100425 Bax Regulation of Pcbd1 1 0.06 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phenylalanine 4-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in phenylalanine 4-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84
2 INT18025 Binding of Pah 32 0.45 30.72 7.93
3 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86
4 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29
5 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88
6 INT9110 Binding of PAH 32 0.41 42.1 3.1
7 INT42485 Binding of Pah 9 0.35 3.42 3.03
8 INT29651 Regulation of Pah 11 0.37 9.95 2.79
9 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53
10 INT200217 Localization of PAH 10 0.36 15.51 2.46
11 INT61685 Positive_regulation of Gene_expression of Pah 6 0.43 4.05 1.79
12 INT25240 Negative_regulation of Pcbd1 11 0.43 3.1 1.59
13 INT22966 Negative_regulation of Positive_regulation of Pah 2 0.50 2.03 1.56
14 INT49466 Negative_regulation of Binding of Pah 2 0.37 0.34 1.24
15 INT127459 Negative_regulation of PAH 18 0.56 15.15 1.05
16 INT9033 Positive_regulation of Pcbd1 14 0.39 3.88 0.86
17 INT66485 Negative_regulation of Binding of Pah 2 0.35 1.27 0.83
18 INT36978 Localization of Pah 9 0.73 7.43 0.82
19 INT249912 Positive_regulation of Negative_regulation of Pah 2 0.43 2.49 0.64
20 INT127460 Positive_regulation of Gene_expression of PAH 5 0.43 4.3 0.5
21 INT160514 Regulation of Positive_regulation of Pah 1 0.22 1.62 0.45
22 INT39150 Gene_expression of Pcbd1 5 0.28 1.3 0.38
23 INT303025 Negative_regulation of Negative_regulation of Pah 1 0.28 1.03 0.34
24 INT45730 Transcription of PAH 3 0.68 2.4 0.33
25 INT127462 Regulation of PAH 5 0.39 3.35 0.29
26 INT9034 Regulation of Pcbd1 6 0.20 3.28 0.28
27 INT127463 Negative_regulation of Positive_regulation of PAH 1 0.30 2.3 0.27
28 INT170924 Negative_regulation of Positive_regulation of Pcbd1 1 0.02 0.4 0.26
29 INT273611 Positive_regulation of Localization of Pah 1 0.40 0.75 0.24
30 INT313869 Gene_expression of Pah 4 0.63 3.1 0.23
31 INT36979 Negative_regulation of Localization of Pah 1 0.39 0.5 0.2
32 INT201196 Negative_regulation of Gene_expression of PAH 2 0.30 3.11 0.19
33 INT213217 Negative_regulation of Binding of PAH 2 0.32 2.03 0.19
34 INT175569 Binding of Pcbd1 1 0.17 0.96 0.19
35 INT230729 Regulation of Gene_expression of Pah 1 0.24 1 0.13
36 INT230730 Negative_regulation of Gene_expression of Pah 2 0.28 1.54 0.12
37 INT345424 Phosphorylation of PAH 1 0.05 1.55 0.11
38 INT188304 Positive_regulation of Positive_regulation of Pah 1 0.18 0.75 0.09
39 INT313868 Positive_regulation of Pah 2 0.41 0.67 0.08
40 INT43108 Binding of Pcbd1 2 0.12 0.16 0.08
41 INT39149 Positive_regulation of Negative_regulation of Pcbd1 1 0.14 0.08 0.08
42 INT313866 Positive_regulation of Positive_regulation of Pah 1 0.41 0.47 0.08
43 INT213213 Protein_catabolism of PAH 1 0.76 1.5 0.07
44 INT303023 Protein_catabolism of Pah 1 0.43 2.06 0.06
45 INT313865 Positive_regulation of Gene_expression of Pah 2 0.47 0.95 0.05
46 INT210503 Positive_regulation of Negative_regulation of PAH 1 0.03 0.65 0.05
47 INT270748 Regulation of Regulation of Pah 1 0.04 1.61 0.04
48 INT201197 Regulation of Gene_expression of PAH 1 0.32 1.72 0.04
49 INT342214 Negative_regulation of Transcription of PAH 1 0.03 0.31 0.03
50 INT175571 Negative_regulation of Pcbd1 1 0.19 0.93 0
51 INT344013 Gene_expression of Pcbd1 1 0.03 0.06 0
52 INT313870 Negative_regulation of Pah 1 0.48 2.33 0
53 INT328696 Negative_regulation of Gene_expression of Pah 1 0.16 0 0
54 INT170926 Regulation of Positive_regulation of Pcbd1 1 0.02 0.22 0
55 INT177542 Localization of Pcbd1 1 0.01 0.1 0
56 INT175570 Positive_regulation of Pcbd1 1 0.21 2.07 0
57 INT303017 Regulation of Localization of Pah 1 0.29 0.85 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox