GO:0004510

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Name tryptophan 5-monooxygenase activity
Categary Function
Go Slim No
Go Link GO:0004510
Unique Molecular Interactions 8
Total Molecular Interactions 8
Total Single Events 220
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for tryptophan 5-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported for tryptophan 5-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT189303 Atp6v1e1 Positive_regulation of Gene_expression of TPH1 1 0.01 0.16 0.73
2 INT160156 Tph2 Regulation of Htr1a 1 0.30 0.75 0.56
3 INT352821 Tph2 Regulation of Tst 1 0.31 0.46 0.36
4 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21
5 INT208763 Binding of CSF2 and TPH1 1 0.07 0.65 0.19
6 INT258614 Positive_regulation of Binding of Foxn1 and Tph2 1 0.46 0.06 0
7 INT258615 Binding of Foxn1 and Tph2 1 0.44 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for tryptophan 5-monooxygenase activity. They are ordered first by their pain relevance and then by number of times they were reported in tryptophan 5-monooxygenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT149015 Gene_expression of Tph2 20 0.78 9.45 10.4
2 INT115296 Gene_expression of TPH1 18 0.77 7.46 10.18
3 INT167457 Negative_regulation of Gene_expression of Tph2 5 0.57 2.27 5.9
4 INT126659 Gene_expression of Tph1 22 0.78 2.04 4.04
5 INT137301 Negative_regulation of Gene_expression of TPH1 5 0.12 1.49 2.98
6 INT248419 Negative_regulation of Tph2 11 0.59 6.32 2.59
7 INT115298 Regulation of Gene_expression of TPH1 1 0.22 2.36 2.33
8 INT61011 Regulation of TPH1 4 0.22 1.17 2.09
9 INT248418 Localization of Tph2 5 0.75 2.45 1.45
10 INT126660 Positive_regulation of Gene_expression of Tph1 5 0.50 0.07 1.43
11 INT122745 Negative_regulation of TPH1 6 0.59 2.94 1.2
12 INT115294 Regulation of Regulation of TPH1 2 0.10 1 0.98
13 INT248421 Regulation of Tph1 1 0.27 0.89 0.87
14 INT344348 Transcription of Tph2 1 0.71 0.98 0.87
15 INT344349 Positive_regulation of Gene_expression of Tph2 1 0.46 0.77 0.8
16 INT208774 Positive_regulation of TPH1 2 0.50 0.71 0.78
17 INT344350 Positive_regulation of Tph2 1 0.69 0.82 0.78
18 INT149014 Negative_regulation of Tph1 5 0.58 1.43 0.74
19 INT149013 Positive_regulation of Tph1 3 0.47 1.1 0.65
20 INT61009 Negative_regulation of Regulation of TPH1 1 0.00 0 0.5
21 INT353976 Negative_regulation of Negative_regulation of Tph2 1 0.42 0 0.35
22 INT248415 Binding of Tph2 9 0.44 3.88 0.34
23 INT332750 Regulation of Gene_expression of Tph1 1 0.11 0 0.33
24 INT268069 Regulation of Tph2 1 0.44 0.26 0.28
25 INT353977 Regulation of Gene_expression of Tph2 1 0.26 0 0.24
26 INT335879 Negative_regulation of Gene_expression of Tph1 1 0.19 0.15 0.21
27 INT248417 Binding of Tph1 1 0.37 1.16 0.16
28 INT248416 Phosphorylation of Tph1 1 0.80 1.04 0.13
29 INT248422 Negative_regulation of Phosphorylation of Tph1 1 0.42 1.04 0.13
30 INT248420 Negative_regulation of Phosphorylation of Tph2 1 0.43 0.99 0.11
31 INT248423 Phosphorylation of Tph2 1 0.81 0.99 0.11
32 INT208775 Binding of TPH1 1 0.37 0.61 0.1
33 INT268076 Positive_regulation of Positive_regulation of Tph1 1 0.28 0.83 0.08
34 INT200429 Positive_regulation of Negative_regulation of TPH1 1 0.01 0.24 0.07
35 INT138234 Transcription of Tph1 1 0.66 0 0
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