GO:0004521

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Name endoribonuclease activity
Categary Function
Go Slim No
Go Link GO:0004521
Unique Molecular Interactions 26
Total Molecular Interactions 36
Total Single Events 119
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endoribonuclease activity. They are ordered first by their pain relevance and then by number of times they were reported for endoribonuclease activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
2 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
3 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
4 INT131810 Nfkb1 Negative_regulation of Localization of Apex1 1 0.01 0.52 0.57
5 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
6 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
7 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
8 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
9 INT253764 Atp9a Positive_regulation of Apex1 1 0.00 0.39 0.08
10 INT316015 AIC Regulation of ERN1 1 0.08 0.1 0.05
11 INT324593 Binding of PROC and RNASEL 1 0.01 0.91 0.03
12 INT287814 Apex1 Positive_regulation of Gene_expression of Rnf128 1 0.03 0.15 0.03
13 INT244458 CS Positive_regulation of ERN1 1 0.17 0.71 0
14 INT244459 ERN1 Regulation of Positive_regulation of MAPK8 1 0.03 0.47 0
15 INT315534 Binding of ACO1 and ERN1 1 0.01 0.18 0
16 INT312661 Binding of CSTF2 and CPSF3 1 0.06 0.08 0
17 INT273480 Binding of EPO and RNASEL 1 0.08 0.77 0
18 INT244481 Binding of ERN1 and ATF6 1 0.17 0.69 0
19 INT273481 Binding of RNASEL and USE1 1 0.02 0.76 0
20 INT273483 Binding of RNASEL and CYSLTR1 1 0.00 0.78 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for endoribonuclease activity. They are ordered first by their pain relevance and then by number of times they were reported in endoribonuclease activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT131808 Localization of Apex1 2 0.16 13.46 4.61
2 INT253756 Gene_expression of Apex1 1 0.14 7.47 1.84
3 INT162467 Gene_expression of ERN1 10 0.56 5.11 1.26
4 INT162471 Positive_regulation of ERN1 7 0.34 3.02 1.08
5 INT162464 Positive_regulation of Gene_expression of ERN1 2 0.36 1.66 0.97
6 INT253750 Positive_regulation of Gene_expression of Apex1 1 0.10 1.43 0.64
7 INT244537 Regulation of ERN1 3 0.26 1.32 0.25
8 INT227426 Positive_regulation of Apex1 2 0.08 1.98 0.23
9 INT120202 Gene_expression of Ern1 2 0.14 1.78 0.21
10 INT253752 Negative_regulation of Localization of Apex1 1 0.08 1.26 0.2
11 INT231317 Localization of ERN1 1 0.65 0.45 0.14
12 INT190501 Regulation of Apex1 1 0.12 0.32 0.1
13 INT273338 Protein_catabolism of Apex1 4 0.05 0.57 0.09
14 INT244534 Negative_regulation of ERN1 2 0.25 1.08 0.09
15 INT183204 Binding of CPSF3 3 0.22 0.48 0.08
16 INT242971 Positive_regulation of Ern1 1 0.04 1.62 0.07
17 INT242970 Phosphorylation of Ern1 1 0.06 0.86 0.03
18 INT306791 Binding of ERN1 1 0.10 0.22 0
19 INT244504 Phosphorylation of ERN1 1 0.47 0.97 0
20 INT244558 Negative_regulation of Gene_expression of ERN1 1 0.24 0.71 0
21 INT243745 Regulation of Binding of CPSF3 1 0.01 0.38 0
22 INT244507 Regulation of Gene_expression of ERN1 1 0.23 0.49 0
23 INT244547 Negative_regulation of Positive_regulation of ERN1 1 0.24 0.06 0
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