GO:0004566

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Name beta-glucuronidase activity
Categary Function
Go Slim No
Go Link GO:0004566
Unique Molecular Interactions 26
Total Molecular Interactions 28
Total Single Events 504
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for beta-glucuronidase activity. They are ordered first by their pain relevance and then by number of times they were reported for beta-glucuronidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109958 Binding of CRH and HPSE 1 0.10 0.72 1.46
2 INT220145 HPSE Negative_regulation of Gene_expression of CRH 1 0.01 0.92 0.64
3 INT13191 FPR1 Positive_regulation of Localization of GUSB 1 0.31 0 0.53
4 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46
5 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45
6 INT12702 Regulation of Binding of FPR1 and GUSB 1 0.43 0.18 0.44
7 INT12703 Binding of FPR1 and GUSB 1 0.36 0.18 0.44
8 INT56633 Gusb Regulation of Mgst1 1 0.03 0.06 0.24
9 INT311191 ecs Negative_regulation of HPSE 1 0.00 0.94 0.12
10 INT190631 Gusb Positive_regulation of Tlr4 1 0.08 0.44 0.11
11 INT354962 Gene_expression of Shank3 Positive_regulation of Gusb 1 0.10 0.45 0.08
12 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08
13 INT159461 SCN5A Negative_regulation of HPSE 1 0.00 0 0.07
14 INT159463 Ptprn2 Negative_regulation of HPSE 1 0.00 0 0.07
15 INT330487 Binding of MME and HPSE 1 0.35 0 0.06
16 INT265753 Binding of FLT1 and KL 1 0.18 0 0
17 INT265759 KL Positive_regulation of Binding of VEGFA 1 0.25 0.14 0
18 INT265747 Binding of KLKB1 and KL 1 0.02 0 0
19 INT162510 Binding of ITPR1 and HPSE 1 0.02 0.05 0
20 INT265769 GOPC Positive_regulation of Gene_expression of KL 1 0.08 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for beta-glucuronidase activity. They are ordered first by their pain relevance and then by number of times they were reported in beta-glucuronidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT12854 Negative_regulation of Gusb 11 0.42 3.25 5.28
2 INT30014 Positive_regulation of HPSE 22 0.70 20.91 4.09
3 INT2877 Localization of GUSB 9 0.80 0.81 3.63
4 INT61734 Regulation of HPSE 16 0.60 13.05 3.5
5 INT1970 Localization of Gusb 11 0.75 3.46 3.42
6 INT1972 Negative_regulation of Localization of Gusb 8 0.55 3.24 3.27
7 INT47011 Positive_regulation of Gusb 14 0.44 8.93 2.87
8 INT96338 Gene_expression of HPSE 17 0.75 18.71 2.73
9 INT4125 Gene_expression of Gusb 6 0.62 2.32 2.13
10 INT58213 Binding of Gusb 4 0.42 1.13 1.72
11 INT151743 Binding of Gusb 11 0.24 8.73 1.63
12 INT2562 Positive_regulation of Gusb 9 0.69 2.92 1.59
13 INT74955 Negative_regulation of HPSE 6 0.57 4.75 1.57
14 INT3164 Positive_regulation of GUSB 4 0.49 2.67 1.47
15 INT67133 Gene_expression of Gusb 14 0.75 18.57 1.37
16 INT47010 Negative_regulation of Gusb 6 0.43 4.16 1.2
17 INT57504 Positive_regulation of Positive_regulation of GUSB 2 0.33 1.25 1.16
18 INT4124 Regulation of Gusb 3 0.22 1.05 1.11
19 INT96229 Localization of HPSE 3 0.20 2.76 1.05
20 INT37747 Localization of Gusb 4 0.69 1.91 0.82
21 INT1971 Positive_regulation of Localization of Gusb 2 0.39 1.25 0.65
22 INT96339 Protein_catabolism of HPSE 5 0.96 2.87 0.63
23 INT3166 Gene_expression of GUSB 4 0.65 0.47 0.62
24 INT2878 Negative_regulation of Localization of GUSB 2 0.59 0.17 0.54
25 INT12705 Regulation of Localization of GUSB 2 0.26 0.24 0.53
26 INT177436 Binding of HPSE 2 0.47 1.81 0.52
27 INT12708 Regulation of GUSB 2 0.44 0.18 0.51
28 INT12706 Binding of GUSB 1 0.35 0.18 0.44
29 INT48326 Negative_regulation of Localization of Gusb 1 0.23 0.65 0.43
30 INT177437 Transcription of HPSE 2 0.23 3.44 0.41
31 INT74954 Positive_regulation of Positive_regulation of HPSE 2 0.40 0.45 0.34
32 INT177439 Negative_regulation of Positive_regulation of HPSE 1 0.21 1.48 0.32
33 INT96337 Positive_regulation of Gene_expression of HPSE 1 0.67 2.28 0.25
34 INT161927 Negative_regulation of Gene_expression of Gusb 2 0.57 2.51 0.24
35 INT65548 Negative_regulation of GUSB 1 0.24 0 0.17
36 INT70831 Protein_catabolism of Gusb 1 0.85 0.33 0.15
37 INT2879 Positive_regulation of Localization of GUSB 1 0.70 0.17 0.14
38 INT330336 Regulation of Positive_regulation of Gusb 1 0.16 1.05 0.12
39 INT158294 Regulation of KL 1 0.37 1.06 0.09
40 INT74953 Positive_regulation of Regulation of HPSE 2 0.49 1.02 0.07
41 INT118191 Regulation of Regulation of HPSE 2 0.26 0.87 0.07
42 INT210222 Phosphorylation of Gusb 1 0.12 0.84 0.07
43 INT138616 Binding of KL 2 0.32 1.96 0.06
44 INT67134 Positive_regulation of Gene_expression of Gusb 3 0.34 1.37 0.05
45 INT202418 Positive_regulation of Binding of Gusb 1 0.35 0.91 0.04
46 INT207842 Gene_expression of KL 3 0.34 2.88 0
47 INT207843 Positive_regulation of Gene_expression of KL 2 0.26 1.1 0
48 INT265796 Positive_regulation of Positive_regulation of KL 1 0.26 0 0
49 INT307865 Regulation of Gene_expression of Gusb 1 0.08 0.09 0
50 INT265810 Positive_regulation of KL 1 0.35 1.04 0
51 INT69479 Protein_catabolism of GUSB 1 0.74 0 0
52 INT188240 Transcription of KL 1 0.54 1.88 0
53 INT335965 Negative_regulation of Localization of HPSE 1 0.11 0.93 0
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