GO:0004602

From wiki-pain
Jump to: navigation, search
Name glutathione peroxidase activity
Categary Function
Go Slim No
Go Link GO:0004602
Unique Molecular Interactions 129
Total Molecular Interactions 168
Total Single Events 1555
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for glutathione peroxidase activity. They are ordered first by their pain relevance and then by number of times they were reported for glutathione peroxidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT48162 RIMS3 Regulation of Localization of LTC4S 1 0.10 2.14 3.25
2 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
3 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
4 INT203162 PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 1.47 0.94
5 INT57746 Il1 Regulation of Gene_expression of Ltc4s 1 0.36 0.33 0.88
6 INT164607 Positive_regulation of GSR Positive_regulation of Gpx1 1 0.01 0.33 0.81
7 INT164606 GSR Positive_regulation of Gpx1 1 0.01 0.32 0.8
8 INT312101 ELANE Regulation of ALOX5AP 1 0.21 1.11 0.73
9 INT164286 Alox5ap Positive_regulation of Cysltr2 1 0.19 1.11 0.61
10 INT164285 Ltc4s Positive_regulation of Cysltr2 1 0.20 1.11 0.61
11 INT164283 Ltb4r Positive_regulation of Ltc4s 1 0.37 1.1 0.6
12 INT164284 Ltb4r Positive_regulation of Alox5ap 1 0.34 1.1 0.6
13 INT335432 Ltc4s Regulation of Cysltr2 1 0.11 0.38 0.58
14 INT335436 Ltc4s Regulation of Gene_expression of Cysltr2 1 0.18 0.38 0.58
15 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53
16 INT122069 Gpx3 Negative_regulation of Trpv1 1 0.02 0.21 0.51
17 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44
18 INT161654 Gsr Regulation of Gpx1 1 0.14 0.85 0.42
19 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42
20 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42
21 INT168461 Sult1a1 Positive_regulation of Gpx1 1 0.12 0.83 0.39
22 INT203167 Gene_expression of PTGER2 Positive_regulation of Gene_expression of ALOX5AP 1 0.03 0.67 0.38
23 INT312102 Binding of ALOX5 and ALOX5AP 1 0.10 0.65 0.36
24 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
25 INT44984 KNG1 Regulation of Ltc4s 1 0.01 0.17 0.3
26 INT263757 Binding of Gpx3 and Neto1 1 0.01 0 0.29
27 INT48161 RIMS3 Negative_regulation of Gene_expression of LTC4S 1 0.16 0.07 0.28
28 INT301671 Ltc4s Positive_regulation of Gene_expression of IL8 1 0.00 0.9 0.27
29 INT127322 Gpx3 Regulation of Mapk1 1 0.00 0.27 0.21
30 INT249893 Ltc4s Positive_regulation of Gpr17 1 0.04 0.92 0.2
31 INT127321 Gpx3 Regulation of Mapk3 1 0.00 0.27 0.2
32 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18
33 INT49057 Positive_regulation of CEL Positive_regulation of Localization of LTC4S 1 0.41 0.28 0.18
34 INT222023 Gpx3 Regulation of Mapk8 1 0.01 1.43 0.18
35 INT312091 ALOX5AP Regulation of Transcription of ALOX5 1 0.13 0.37 0.18
36 INT33362 Binding of Ltc4s and Cysltr1 1 0.16 0.21 0.17
37 INT249895 Ltc4s Positive_regulation of P2ry4 1 0.00 0.71 0.17
38 INT312089 LTB4R Positive_regulation of ALOX5AP 1 0.01 0.32 0.16
39 INT193216 Binding of LTC4S and CYSLTR1 1 0.04 0.71 0.16
40 INT312126 ELANE Positive_regulation of ALOX5AP 1 0.20 0.25 0.15
41 INT56430 Ltc4s Regulation of NA 1 0.00 0 0.14
42 INT17437 LTC4S Positive_regulation of CYSLTR1 1 0.03 0.2 0.13
43 INT252573 Rpe Negative_regulation of Gpx1 1 0.07 2.34 0.13
44 INT270996 TBXA2R Regulation of LTC4S 1 0.24 0.83 0.13
45 INT143661 Abl1 Regulation of Gpx1 1 0.19 0.56 0.12
46 INT271002 Binding of LTC4S and Aia1 1 0.00 0.98 0.12
47 INT143662 Rere Regulation of Gpx1 1 0.69 0.56 0.12
48 INT79018 Binding of GSTT1 and Gstt1 1 0.27 0.2 0.12
49 INT301307 Binding of GPR17 and LTC4S 1 0.00 0.42 0.11
50 INT312116 Negative_regulation of PTGER2 Regulation of Gene_expression of ALOX5AP 1 0.04 0.2 0.1
51 INT273354 Binding of ALOX5 and LTC4S 1 0.04 0.19 0.09
52 INT153696 Binding of GSTM1 and Gstt1 1 0.06 0.71 0.08
53 INT313503 Binding of ALOX5AP and CXADRP1 1 0.01 1.51 0.08
54 INT312093 ELANE Regulation of Gene_expression of ALOX5AP 1 0.13 0.15 0.08
55 INT312113 ELANE Positive_regulation of Gene_expression of ALOX5AP 1 0.23 0.14 0.07
56 INT192309 Binding of GSTM1 and GSTT1 2 0.43 4.54 0.06
57 INT208432 Sms Negative_regulation of Negative_regulation of Gpx1 1 0.14 0.61 0.05
58 INT208433 Sms Positive_regulation of Gene_expression of Gpx1 1 0.25 0.53 0.05
59 INT313504 Binding of ALOX5AP and SNRNP70 1 0.04 0.5 0.05
60 INT192263 LTC4S Positive_regulation of Gene_expression of TIMP1 1 0.00 0.28 0.04
61 INT347414 Tlr4 Negative_regulation of Gpx1 1 0.01 0.36 0.04
62 INT312117 Negative_regulation of ELANE Positive_regulation of ALOX5AP 1 0.17 0.08 0.04
63 INT252767 CAT Regulation of Gpx1 1 0.00 0.25 0.04
64 INT247765 Gpx3 Positive_regulation of Rarres2 1 0.01 0.86 0.03
65 INT347514 Binding of CYSLTR1 and Ltc4s 1 0.01 0.58 0.03
66 INT313551 Binding of ALOX5AP and Cor 1 0.02 1.01 0.03
67 INT347516 Binding of CYSLTR2 and Ltc4s 1 0.01 0.4 0.03
68 INT286268 Binding of GSR and Gpx1 2 0.02 0 0
69 INT155123 Binding of Gpx1 and Cat 1 0.04 0.05 0
70 INT313499 Binding of ALOX5AP and CRP 1 0.07 0.45 0
71 INT198918 Binding of Gpx3 and Lrp8 1 0.00 0.17 0
72 INT155124 Positive_regulation of Binding of Gpx1 and Cat 1 0.05 0.05 0
73 INT313502 Binding of ALOX5AP and ADIPOQ 1 0.05 0.44 0
74 INT263731 Positive_regulation of Binding of Gpx3 and Neto1 1 0.01 0 0
75 INT172893 Binding of Lta4h and Ltc4s 1 0.00 0.24 0
76 INT351596 Regulation of Binding of GSR and Gpx1 1 0.02 0 0
77 INT298871 ALOX5AP Positive_regulation of RAB7A 1 0.09 0.35 0
78 INT206963 Lipg Regulation of Gpx1 1 0.00 0.5 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for glutathione peroxidase activity. They are ordered first by their pain relevance and then by number of times they were reported in glutathione peroxidase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61513 Positive_regulation of Gpx1 71 0.64 37.91 17.07
2 INT195414 Gene_expression of ALOX5AP 65 0.72 31.22 15.25
3 INT7997 Gene_expression of Ltc4s 51 0.76 34.28 13.8
4 INT41313 Gene_expression of Gpx1 68 0.78 34.24 11.77
5 INT4808 Gene_expression of LTC4S 37 0.73 18.36 9.62
6 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83
7 INT4807 Localization of LTC4S 23 0.58 6.89 7.59
8 INT10606 Localization of Ltc4s 16 0.75 10.14 5.05
9 INT10605 Positive_regulation of Ltc4s 21 0.68 17.22 4.8
10 INT20743 Positive_regulation of Gene_expression of Ltc4s 13 0.60 12.3 3.86
11 INT10162 Positive_regulation of Gpx3 10 0.40 3.37 3.68
12 INT64539 Gene_expression of Gpx3 14 0.58 9.42 3.64
13 INT53584 Regulation of Gpx1 19 0.62 14.38 3.48
14 INT16159 Regulation of Ltc4s 11 0.38 2.52 3.21
15 INT195415 Regulation of Gene_expression of ALOX5AP 10 0.45 6.43 3.13
16 INT90289 Positive_regulation of Gene_expression of Gpx1 10 0.17 8.07 3.05
17 INT4811 Positive_regulation of Gene_expression of LTC4S 5 0.65 3.29 2.92
18 INT195421 Positive_regulation of Gene_expression of ALOX5AP 12 0.49 5.17 2.82
19 INT16089 Gene_expression of Ltc4s 11 0.77 3.37 2.29
20 INT200779 Negative_regulation of Gene_expression of ALOX5AP 7 0.41 3.75 1.79
21 INT164275 Gene_expression of Alox5ap 3 0.55 3.79 1.72
22 INT94848 Negative_regulation of Gene_expression of Gpx1 11 0.30 4.91 1.7
23 INT200778 Positive_regulation of ALOX5AP 3 0.49 2.54 1.7
24 INT15996 Binding of Ltc4s 9 0.35 5.66 1.64
25 INT67869 Transcription of Gpx1 3 0.68 0.67 1.56
26 INT122204 Positive_regulation of Alox5ap 1 0.26 0.23 1.53
27 INT35788 Phosphorylation of Gpx3 5 0.06 0.66 1.52
28 INT164277 Transcription of Ltc4s 3 0.47 2.69 1.36
29 INT124996 Regulation of Gpx3 4 0.23 1.54 1.34
30 INT12545 Negative_regulation of Ltc4s 8 0.42 2.53 1.07
31 INT89887 Regulation of Gene_expression of Gpx1 3 0.32 0.8 1.02
32 INT79017 Gene_expression of GSTT1 23 0.73 13.16 0.97
33 INT24581 Negative_regulation of LTC4S 2 0.40 2.05 0.91
34 INT76915 Localization of Gpx3 6 0.14 4.48 0.89
35 INT13543 Positive_regulation of LTC4S 5 0.58 2.26 0.88
36 INT16088 Negative_regulation of Gene_expression of Ltc4s 6 0.58 0.29 0.85
37 INT68926 Binding of ALOX5AP 8 0.36 4.02 0.84
38 INT77357 Regulation of Gstt1 2 0.50 0.8 0.83
39 INT198870 Binding of Gpx3 5 0.01 2.47 0.81
40 INT77359 Positive_regulation of Gstt1 3 0.56 0.33 0.78
41 INT168432 Negative_regulation of Positive_regulation of Gpx1 4 0.40 2.89 0.75
42 INT13541 Positive_regulation of Localization of LTC4S 3 0.51 1.01 0.75
43 INT48164 Negative_regulation of Gene_expression of LTC4S 3 0.55 0.22 0.74
44 INT198898 Protein_catabolism of Gpx3 6 0.02 2.49 0.71
45 INT79016 Gene_expression of Gstt1 4 0.44 0.59 0.7
46 INT34859 Positive_regulation of Localization of Ltc4s 2 0.34 1.26 0.7
47 INT57111 Negative_regulation of Localization of Ltc4s 1 0.27 1.02 0.62
48 INT65607 Regulation of Gene_expression of LTC4S 1 0.58 0.25 0.61
49 INT164276 Localization of Alox5ap 1 0.61 1.1 0.6
50 INT148230 Positive_regulation of Regulation of Gpx1 1 0.31 0.58 0.6
51 INT49507 Negative_regulation of Ltc4s 1 0.16 0.61 0.59
52 INT28417 Negative_regulation of Regulation of Ltc4s 1 0.03 0 0.56
53 INT43459 Positive_regulation of Positive_regulation of Ltc4s 2 0.11 2.47 0.5
54 INT195097 Positive_regulation of Gene_expression of Gpx3 4 0.45 1.09 0.47
55 INT317984 Positive_regulation of Localization of Gpx3 1 0.01 1.42 0.46
56 INT122205 Negative_regulation of Alox5ap 1 0.24 0 0.45
57 INT15997 Negative_regulation of Binding of Ltc4s 2 0.43 0.33 0.42
58 INT13542 Negative_regulation of Localization of LTC4S 1 0.27 1.02 0.39
59 INT195416 Regulation of ALOX5AP 2 0.53 0.8 0.38
60 INT195413 Negative_regulation of ALOX5AP 5 0.37 1.39 0.37
61 INT38789 Regulation of LTC4S 3 0.51 1.1 0.37
62 INT132064 Regulation of Binding of Ltc4s 1 0.22 1.02 0.37
63 INT110954 Negative_regulation of Gene_expression of GSTT1 1 0.41 0.41 0.36
64 INT309930 Regulation of Gene_expression of Ltc4s 1 0.08 2.79 0.34
65 INT137586 Binding of Gpx1 8 0.23 2.76 0.29
66 INT20229 Negative_regulation of Positive_regulation of Ltc4s 2 0.23 0.87 0.29
67 INT116703 Negative_regulation of Negative_regulation of Gpx1 3 0.18 0.81 0.28
68 INT171007 Transcription of LTC4S 1 0.16 0.61 0.28
69 INT273358 Binding of LTC4S 4 0.17 0.88 0.27
70 INT132595 Binding of Gstt1 2 0.13 1.78 0.24
71 INT203173 Localization of ALOX5AP 3 0.48 0.78 0.21
72 INT259884 Negative_regulation of Binding of ALOX5AP 1 0.10 0.46 0.21
73 INT274775 Regulation of Positive_regulation of Gpx1 1 0.04 0.76 0.2
74 INT117253 Regulation of Gene_expression of GSTT1 1 0.45 0.6 0.2
75 INT312127 Positive_regulation of Positive_regulation of ALOX5AP 1 0.35 0.37 0.19
76 INT117252 Regulation of GSTT1 3 0.45 12.44 0.18
77 INT33357 Positive_regulation of Gene_expression of Ltc4s 1 0.45 0.22 0.18
78 INT312137 Transcription of ALOX5AP 1 0.50 0.37 0.18
79 INT21351 Negative_regulation of Gene_expression of Ltc4s 3 0.19 1.14 0.17
80 INT177568 Localization of Gpx1 5 0.49 1.82 0.16
81 INT143657 Phosphorylation of Gpx1 1 0.82 0.97 0.14
82 INT143658 Regulation of Phosphorylation of Gpx1 1 0.45 0.97 0.14
83 INT143659 Positive_regulation of Phosphorylation of Gpx1 1 0.50 0.98 0.14
84 INT314341 Positive_regulation of Localization of Gpx1 1 0.08 0.82 0.13
85 INT312135 Negative_regulation of Regulation of ALOX5AP 1 0.30 0.19 0.13
86 INT192311 Binding of GSTT1 7 0.48 10.62 0.12
87 INT79015 Negative_regulation of Gstt1 3 0.39 0.24 0.11
88 INT166890 Regulation of Binding of ALOX5AP 1 0.44 0.1 0.1
89 INT252568 Negative_regulation of Regulation of Gpx1 1 0.08 1.11 0.09
90 INT60010 Regulation of Positive_regulation of Ltc4s 1 0.06 0 0.08
91 INT76914 Regulation of Localization of LTC4S 1 0.15 0.31 0.08
92 INT327731 Positive_regulation of Ltc4s 2 0.24 0.91 0.07
93 INT312129 Positive_regulation of Transcription of ALOX5AP 1 0.35 0.1 0.05
94 INT344420 Localization of Ltc4s 1 0.27 0.4 0.05
95 INT202207 Negative_regulation of Binding of GSTT1 2 0.42 0.77 0.03
96 INT312132 Regulation of Regulation of ALOX5AP 1 0.28 0.06 0.03
97 INT16160 Regulation of Localization of Ltc4s 1 0.17 0.2 0.03
98 INT202203 Positive_regulation of GSTT1 4 0.47 1.26 0
99 INT202208 Localization of GSTT1 3 0.74 3.91 0
100 INT279624 Negative_regulation of Gpx3 2 0.18 0.67 0
101 INT244365 Regulation of Binding of GSTT1 1 0.61 4.62 0
102 INT239147 Regulation of Binding of Gpx1 1 0.28 0.53 0
103 INT268724 Positive_regulation of Negative_regulation of Gpx1 1 0.04 0.13 0
104 INT235707 Binding of Ltc4s 1 0.10 0 0
105 INT244361 Regulation of Transcription of GSTT1 1 0.45 1.29 0
106 INT79014 Positive_regulation of Gene_expression of Gstt1 1 0.31 0 0
107 INT244363 Transcription of GSTT1 1 0.68 1.23 0
108 INT210664 Negative_regulation of Gene_expression of Gpx3 1 0.13 0.13 0
109 INT203876 Positive_regulation of Gene_expression of GSTT1 1 0.50 0.18 0
110 INT335757 Positive_regulation of Positive_regulation of Gpx1 1 0.07 0.66 0
111 INT203878 Phosphorylation of GSTT1 1 0.80 0.22 0
112 INT347402 Negative_regulation of Binding of Gpx1 1 0.05 0 0
113 INT351593 Positive_regulation of Binding of Gpx1 1 0.08 0 0
114 INT206503 Negative_regulation of GSTT1 1 0.34 0.97 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox