GO:0004620

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Name phospholipase activity
Categary Function
Go Slim No
Go Link GO:0004620
Unique Molecular Interactions 50
Total Molecular Interactions 59
Total Single Events 644
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phospholipase activity. They are ordered first by their pain relevance and then by number of times they were reported for phospholipase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91350 Binding of Pla2g4a and RYBP 1 0.00 1.15 2.65
2 INT66767 Il1b Positive_regulation of Pla2g10 1 0.05 0.47 1.13
3 INT317559 Binding of Hint1 and Pla2g4a 1 0.01 0.06 0.94
4 INT231390 Pla2g4a Regulation of Pla2g2a 1 0.08 0.92 0.77
5 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77
6 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
7 INT308484 Car2 Positive_regulation of Pla2g4a 1 0.03 1.23 0.65
8 INT66766 Casp1 Positive_regulation of Transcription of Pla2g10 1 0.06 0.19 0.6
9 INT66768 Il1b Positive_regulation of Transcription of Pla2g10 1 0.05 0.22 0.6
10 INT66769 Negative_regulation of Il1b Positive_regulation of Pla2g10 1 0.04 0.25 0.53
11 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
12 INT206961 Lipg Regulation of Ptger2 1 0.01 0.85 0.51
13 INT206958 Lipg Regulation of Gene_expression of Ptger2 1 0.01 0.85 0.51
14 INT344714 Nr1h4 Negative_regulation of Gene_expression of Lipg 1 0.02 0.77 0.23
15 INT277072 Binding of PLA2G7 and Lipg 1 0.00 1.32 0.21
16 INT335053 PPARA Positive_regulation of Gene_expression of LPL 1 0.21 0.34 0.19
17 INT334770 Ednra Positive_regulation of Pla2g4a 1 0.00 0.24 0.14
18 INT155388 Binding of LPA and Lipg 1 0.00 1.22 0.12
19 INT303990 Binding of Lep and Positive_regulation of Gene_expression of LPL 1 0.03 0.35 0.1
20 INT83271 Gda Negative_regulation of Napepld 1 0.05 0 0.1
21 INT327557 Pla2g4a Positive_regulation of Phosphorylation of Ptgs2 1 0.14 1.03 0.1
22 INT165619 Binding of LPL and TGS1 1 0.04 0.61 0.09
23 INT313846 Olr407 Negative_regulation of Lipg 1 0.00 0.55 0.09
24 INT327559 Pla2g4a Positive_regulation of Gene_expression of Ptgs2 1 0.14 1 0.09
25 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
26 INT197777 Pla2g10 Regulation of Pla2g2a 1 0.02 0.61 0.08
27 INT197776 Pla2g10 Regulation of Pla2g4a 1 0.18 0.61 0.08
28 INT315969 Binding of Lipg and Msc 1 0.01 0.14 0.06
29 INT86448 Binding of Cnr1 and Lipg 1 0.28 0.64 0.06
30 INT183302 Tchol1 Negative_regulation of Lipg 1 0.00 0.52 0.05
31 INT337386 Lipg Regulation of GK2 1 0.00 0.15 0.05
32 INT239438 Binding of OPA1 and LIPG 1 0.03 1.21 0.04
33 INT251963 Binding of HSD11B1 and LIPC 1 0.15 0.35 0.03
34 INT230423 INS Negative_regulation of Lipg 1 0.03 0.74 0.03
35 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
36 INT295980 Dap Positive_regulation of Lipg 1 0.17 0.48 0
37 INT332905 Binding of LPL and SNRNP70 1 0.01 1.34 0
38 INT214472 Binding of LPL and GPIHBP1 1 0.29 1.17 0
39 INT88766 Binding of LIPC and CASZ1 1 0.03 0 0
40 INT171600 INCENP Negative_regulation of Lipg 1 0.00 0.38 0
41 INT323571 Lipg Positive_regulation of Positive_regulation of Mag 1 0.00 0.15 0
42 INT206959 Lipg Regulation of Cat 1 0.02 0.5 0
43 INT258725 Binding of GPD1 and Lipg 1 0.12 0.13 0
44 INT309889 Positive_regulation of CNR1 Positive_regulation of LPL 1 0.05 1.25 0
45 INT258712 Binding of Gpd1 and Lipg 1 0.11 0.14 0
46 INT171602 APOC3 Negative_regulation of Lipg 1 0.04 0.38 0
47 INT253086 INS Negative_regulation of LPL 1 0.08 0.56 0
48 INT170211 Binding of HSD11B1 and LPL 1 0.02 1.47 0
49 INT206963 Lipg Regulation of Gpx1 1 0.00 0.5 0
50 INT332907 Binding of LPL and SUGT1 1 0.00 1.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phospholipase activity. They are ordered first by their pain relevance and then by number of times they were reported in phospholipase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113399 Positive_regulation of Pla2g4a 36 0.67 33.83 18.78
2 INT86813 Gene_expression of Pla2g4a 26 0.75 42.31 10.07
3 INT47994 Negative_regulation of Lipg 45 0.50 27.19 7.24
4 INT66760 Gene_expression of Pla2g10 8 0.76 4.43 4.83
5 INT66762 Negative_regulation of Pla2g10 6 0.48 7.8 4.54
6 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26
7 INT156416 Gene_expression of Lipg 38 0.67 18.35 4.07
8 INT18515 Gene_expression of Lipg 18 0.66 9.3 3.72
9 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17
10 INT12237 Positive_regulation of Lipg 19 0.60 11.09 2.92
11 INT126172 Negative_regulation of Pla2g4a 7 0.39 9.01 2.89
12 INT122376 Localization of Pla2g4a 12 0.73 7.18 2.58
13 INT118251 Localization of Pla2g10 5 0.73 3.07 2.55
14 INT17961 Regulation of Pla2g4a 9 0.25 4.86 2.3
15 INT86814 Transcription of Pla2g4a 4 0.49 2.35 2.14
16 INT22843 Localization of Lipg 5 0.33 1.95 2.12
17 INT45176 Negative_regulation of LPL 34 0.59 22.22 2.01
18 INT45838 Positive_regulation of LPL 15 0.69 11.33 2
19 INT4691 Regulation of Lipg 10 0.61 4.7 1.99
20 INT118250 Positive_regulation of Gene_expression of Pla2g10 3 0.49 2.47 1.93
21 INT268619 Phosphorylation of Pla2g4a 5 0.69 2.14 1.36
22 INT86446 Protein_catabolism of Lipg 9 0.50 3.52 1.25
23 INT66759 Transcription of Pla2g10 1 0.59 0.41 1.19
24 INT86812 Negative_regulation of Transcription of Pla2g4a 1 0.13 0.49 1.18
25 INT38265 Gene_expression of LPL 22 0.78 10.59 1.09
26 INT142914 Negative_regulation of Localization of Lipg 1 0.14 0.49 1.04
27 INT86816 Negative_regulation of Gene_expression of Pla2g4a 3 0.50 2.27 0.93
28 INT205888 Positive_regulation of Gene_expression of Pla2g4a 7 0.67 8 0.9
29 INT168990 Positive_regulation of Positive_regulation of Pla2g4a 2 0.43 2.14 0.86
30 INT197772 Positive_regulation of Pla2g10 1 0.38 5.94 0.85
31 INT77928 Binding of Pla2g4a 3 0.10 2.5 0.84
32 INT207565 Negative_regulation of LIPG 8 0.10 7.83 0.76
33 INT169652 Positive_regulation of Protein_catabolism of Lipg 1 0.28 0.07 0.72
34 INT113400 Positive_regulation of Transcription of Pla2g4a 1 0.08 0.96 0.7
35 INT308475 Regulation of Positive_regulation of Pla2g4a 1 0.09 1.14 0.67
36 INT335102 Positive_regulation of Positive_regulation of LPL 1 0.14 1.48 0.66
37 INT66763 Negative_regulation of Transcription of Pla2g10 1 0.48 0.22 0.61
38 INT66765 Negative_regulation of Gene_expression of Pla2g10 1 0.48 0.27 0.58
39 INT45839 Regulation of LPL 10 0.55 7.64 0.55
40 INT174813 Localization of LIPG 3 0.05 1.18 0.55
41 INT21871 Binding of Lipg 4 0.14 0.78 0.53
42 INT48694 Regulation of Gene_expression of Lipg 2 0.21 1.5 0.51
43 INT21339 Phosphorylation of Lipg 1 0.19 0.66 0.51
44 INT145467 Positive_regulation of Napepld 1 0.38 0 0.51
45 INT145466 Regulation of Napepld 1 0.25 0 0.47
46 INT126683 Localization of Lipg 7 0.70 3.87 0.46
47 INT18514 Positive_regulation of Positive_regulation of Lipg 1 0.13 0.15 0.43
48 INT197775 Regulation of Pla2g10 1 0.17 2.26 0.39
49 INT126173 Negative_regulation of Regulation of Pla2g4a 1 0.40 1.01 0.37
50 INT126174 Positive_regulation of Regulation of Pla2g4a 1 0.37 1.03 0.34
51 INT205894 Regulation of Gene_expression of Pla2g4a 3 0.52 1.9 0.33
52 INT199121 Positive_regulation of Gene_expression of Lipg 4 0.13 2.44 0.32
53 INT3959 Regulation of Lipg 6 0.27 2.48 0.29
54 INT213281 Localization of LPL 3 0.21 3.48 0.28
55 INT88770 Negative_regulation of LIPC 1 0.37 0.17 0.28
56 INT126171 Negative_regulation of Positive_regulation of Pla2g4a 1 0.39 0.91 0.27
57 INT238864 Positive_regulation of Gene_expression of LPL 5 0.24 2.39 0.26
58 INT77031 Gene_expression of LIPG 4 0.51 4.32 0.26
59 INT86447 Binding of Lipg 3 0.18 1.51 0.25
60 INT21340 Regulation of Phosphorylation of Lipg 1 0.14 0.35 0.24
61 INT312523 Negative_regulation of Phosphorylation of Pla2g4a 1 0.16 0.68 0.22
62 INT312522 Positive_regulation of Phosphorylation of Pla2g4a 1 0.14 0.68 0.21
63 INT45473 Positive_regulation of LIPC 3 0.20 5.49 0.2
64 INT83267 Gene_expression of Napepld 1 0.67 0 0.19
65 INT42014 Regulation of Localization of Lipg 1 0.16 0.19 0.19
66 INT39694 Regulation of LIPC 2 0.58 0.89 0.14
67 INT111337 Protein_catabolism of Lipg 2 0.66 0.43 0.13
68 INT217684 Positive_regulation of LIPG 3 0.04 1.9 0.12
69 INT84395 Protein_catabolism of Pla2g4a 1 0.02 0.41 0.12
70 INT117686 Regulation of LIPG 2 0.04 0.49 0.1
71 INT83269 Negative_regulation of Napepld 1 0.43 0 0.1
72 INT212876 Negative_regulation of Gene_expression of Lipg 1 0.06 0.37 0.1
73 INT213274 Negative_regulation of Localization of LPL 1 0.15 1.89 0.09
74 INT63322 Protein_catabolism of LPL 2 0.57 0.33 0.08
75 INT41694 Transcription of Lipg 1 0.53 0.85 0.08
76 INT253445 Positive_regulation of Binding of Pla2g4a 1 0.12 0.91 0.06
77 INT211566 Localization of LIPC 3 0.61 2.31 0.05
78 INT211567 Gene_expression of LIPC 1 0.09 1.55 0.05
79 INT292414 Regulation of Negative_regulation of Lipg 2 0.09 0.7 0.04
80 INT206957 Negative_regulation of Gene_expression of Lipg 3 0.08 1.01 0.03
81 INT173168 Regulation of Gene_expression of LPL 2 0.14 0.29 0.03
82 INT258794 Positive_regulation of Positive_regulation of LIPG 1 0.03 0.57 0.03
83 INT293300 Regulation of Positive_regulation of LIPC 1 0.13 1.6 0.03
84 INT297359 Phosphorylation of LPL 1 0.19 0.62 0.03
85 INT293299 Negative_regulation of Positive_regulation of LIPC 1 0.12 1.59 0.03
86 INT237344 Negative_regulation of Phosphorylation of Lipg 3 0.14 0.49 0
87 INT237349 Phosphorylation of Lipg 2 0.26 0.82 0
88 INT102264 Positive_regulation of Gene_expression of Lipg 2 0.35 0.3 0
89 INT214478 Binding of LPL 2 0.25 1.91 0
90 INT251000 Transcription of LPL 1 0.39 0.05 0
91 INT251966 Binding of LIPC 1 0.33 1.08 0
92 INT281264 Positive_regulation of Negative_regulation of Lipg 1 0.07 0.5 0
93 INT238868 Negative_regulation of Gene_expression of LPL 1 0.15 0.73 0
94 INT337080 Positive_regulation of Localization of Pla2g4a 1 0.18 1 0
95 INT292412 Negative_regulation of Positive_regulation of Lipg 1 0.05 0.07 0
96 INT63323 Regulation of Protein_catabolism of LPL 1 0.24 0 0
97 INT63321 Positive_regulation of Binding of Lipg 1 0.02 0 0
98 INT179190 Negative_regulation of Positive_regulation of Lipg 1 0.51 0.62 0
99 INT212381 Negative_regulation of Positive_regulation of LPL 1 0.13 1.31 0
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