GO:0004697

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Name protein kinase C activity
Categary Function
Go Slim No
Go Link GO:0004697
Unique Molecular Interactions 646
Total Molecular Interactions 777
Total Single Events 6380
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein kinase C activity. They are ordered first by their pain relevance and then by number of times they were reported for protein kinase C activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
2 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
3 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
4 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
5 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
6 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
7 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
8 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
9 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
10 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
11 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
12 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
13 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
14 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
15 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
16 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
17 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
18 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
19 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
20 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
21 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
22 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
23 INT122428 Binding of Ighm and Prkci 1 0.00 0 1.66
24 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
25 INT135516 PRKCA Negative_regulation of Phosphorylation of OPRM1 1 0.12 0 1.62
26 INT118515 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TRPV1 1 0.27 0.56 1.58
27 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
28 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
29 INT166676 Binding of PRKCA and UGT1A6 1 0.30 0 1.5
30 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
31 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
32 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
33 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
34 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
35 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
36 INT122430 Negative_regulation of Binding of Ighm and Prkci 1 0.00 0 1.36
37 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
38 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
39 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
40 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
41 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
42 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
43 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
44 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
45 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
46 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
47 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
48 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
49 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
50 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
51 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1
52 INT323175 PRKCA Positive_regulation of Akt1 1 0.02 0 1.1
53 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
54 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
55 INT122432 Prkci Regulation of Negative_regulation of Oprd1 1 0.01 0 1.06
56 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
57 INT122429 Prkci Regulation of Gene_expression of Ighm 1 0.00 0 1.02
58 INT122431 Prkci Negative_regulation of Negative_regulation of Ighm 1 0.00 0 1.02
59 INT122433 Prkci Negative_regulation of Ighm 1 0.00 0 1.02
60 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
61 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
62 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
63 INT69307 Prkcq Negative_regulation of TH1L 1 0.00 0.98 0.98
64 INT69506 CA2 Positive_regulation of PRKCA 1 0.50 0.42 0.98
65 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
66 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
67 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
68 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
69 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
70 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
71 INT72213 Positive_regulation of PRKCA Regulation of Gene_expression of METTL3 1 0.05 0.17 0.93
72 INT78976 Prkcg Regulation of Ina 1 0.13 0.16 0.93
73 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
74 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
75 INT159995 Prkcg Regulation of Gene_expression of Bace1 1 0.39 0.32 0.91
76 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
77 INT167767 Prkcz Positive_regulation of Phosphorylation of Sigmar1 1 0.04 0.23 0.9
78 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9
79 INT167766 Prkcz Positive_regulation of Positive_regulation of Sigmar1 1 0.04 0.23 0.9
80 INT12766 Ins1 Positive_regulation of Prkcg 3 0.53 0.07 0.89
81 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
82 INT113383 Negative_regulation of Sert1 Positive_regulation of Prkcg 1 0.31 0 0.89
83 INT152835 Prkcg Regulation of Phosphorylation of Nfasc 1 0.10 0.21 0.87
84 INT152853 Prkcg Regulation of PRS 1 0.01 0.21 0.87
85 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
86 INT80792 Prkcg Regulation of Oprd1 1 0.19 0.2 0.86
87 INT80793 Prkcg Regulation of Pkm2 1 0.29 0.2 0.83
88 INT189671 DAG1 Positive_regulation of PRKCA 3 0.12 0.71 0.82
89 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
90 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
91 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
92 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
93 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
94 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
95 INT240456 Ephb1 Regulation of Prkcg 1 0.19 0.51 0.79
96 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
97 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
98 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
99 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
100 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
101 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
102 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
103 INT167770 Sigmar1 Positive_regulation of Prkcz 1 0.04 0.34 0.77
104 INT152831 Nefh Regulation of Prkcg 1 0.05 0.19 0.77
105 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
106 INT152836 Nefm Regulation of Prkcg 1 0.15 0.19 0.77
107 INT167768 Regulation of Sigmar1 Positive_regulation of Prkcz 1 0.02 0.34 0.77
108 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
109 INT152854 PRS Regulation of Prkcg 1 0.01 0.19 0.76
110 INT166674 YY1 Regulation of Binding of PRKCA 1 0.38 0 0.75
111 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74
112 INT219914 Prkcg Regulation of Phosphorylation of Trpv1 1 0.11 1 0.74
113 INT124353 Prkcg Positive_regulation of Positive_regulation of Gorasp2 1 0.02 1.19 0.73
114 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72
115 INT351351 Prkcg Regulation of Lpar1 1 0.12 0.58 0.72
116 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71
117 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71
118 INT263236 DAG1 Positive_regulation of Prkcg 2 0.01 0.31 0.7
119 INT186162 Phosphorylation of Prkaca Positive_regulation of Phosphorylation of Prkcg 1 0.04 0.22 0.7
120 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
121 INT166673 PRKCA Negative_regulation of UGT1A6 1 0.36 0 0.69
122 INT299989 PRKCA Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.67
123 INT189704 PRKCA Regulation of CHKB 1 0.13 0.18 0.66
124 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
125 INT171825 Binding of Prkcg and Ncs1 1 0.00 0.07 0.66
126 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66
127 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
128 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
129 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
130 INT265144 Olah Positive_regulation of Prkcg 1 0.02 0 0.62
131 INT265140 Olah Regulation of Prkcg 1 0.01 0 0.62
132 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62
133 INT221246 Prkca Negative_regulation of Ptpn2 1 0.04 0.54 0.6
134 INT81606 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.29 0 0.6
135 INT131072 Cc2d1b Negative_regulation of Prkcg 1 0.01 0 0.58
136 INT270943 Binding of Prkcg and Cpe 1 0.05 0 0.58
137 INT81605 PRKCA Positive_regulation of Phosphorylation of TACR1 1 0.43 0 0.57
138 INT263230 Prkcg Regulation of Trpv1 1 0.05 0.95 0.56
139 INT323176 PRKCA Positive_regulation of Phosphorylation of Akt1 1 0.02 0 0.56
140 INT323148 PRKCA Positive_regulation of RAF1 1 0.01 0 0.55
141 INT78973 Prkcg Positive_regulation of Positive_regulation of Ina 1 0.10 0.07 0.55
142 INT296483 Prkca Positive_regulation of Localization of GRIP1 1 0.02 0.31 0.55
143 INT263231 Positive_regulation of Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.55
144 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
145 INT323150 PRKCA Positive_regulation of Phosphorylation of RAF1 1 0.01 0 0.55
146 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
147 INT263229 Trpv1 Positive_regulation of Prkcg 1 0.08 0.57 0.54
148 INT323146 PRKCA Positive_regulation of MAPK1 1 0.02 0 0.54
149 INT182553 Ptger2 Regulation of Localization of Prkca 1 0.08 0.69 0.53
150 INT97425 Prkcg Regulation of Regulation of Nos1 1 0.06 0 0.53
151 INT137685 Phosphorylation of Prkca Negative_regulation of Binding of Srpx2 1 0.18 0 0.53
152 INT235876 Hspg2 Positive_regulation of Prkca 1 0.03 0.23 0.53
153 INT330544 Bcl2l11 Negative_regulation of Prkcg 1 0.03 0.38 0.52
154 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
155 INT330541 Bcl2l11 Negative_regulation of Negative_regulation of Prkcg 1 0.03 0.38 0.52
156 INT144130 Binding of Gja1 and Prkcg 1 0.48 0.5 0.52
157 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
158 INT151220 Negative_regulation of SIGMAR1 Negative_regulation of Positive_regulation of Prkca 1 0.00 0.13 0.51
159 INT151219 Negative_regulation of SIGMAR1 Negative_regulation of Prkca 1 0.00 0.13 0.51
160 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
161 INT160203 Prkcc Positive_regulation of Src 1 0.02 0 0.51
162 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
163 INT189688 PRKCA Regulation of Transcription of TERT 1 0.13 0.2 0.5
164 INT189696 PRKCA Negative_regulation of Negative_regulation of TEP1 1 0.02 0.15 0.5
165 INT189680 PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
166 INT189675 Negative_regulation of PRKCA Negative_regulation of TEP1 1 0.02 0.15 0.5
167 INT235885 Prkca Negative_regulation of Slc6a4 1 0.05 0.14 0.49
168 INT153580 Binding of Prkcc and Hint1 1 0.03 0 0.49
169 INT114543 Bdnf Positive_regulation of Prkcg 1 0.21 0 0.49
170 INT330543 Prkcg Regulation of Regulation of Trpm8 1 0.11 0.28 0.47
171 INT261648 BDKRB1 Regulation of PRKCA 1 0.03 1.9 0.47
172 INT296466 Prkca Regulation of Phosphorylation of Rbm39 1 0.00 0.27 0.47
173 INT153658 PRKCA Negative_regulation of GEM 1 0.01 0.22 0.46
174 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46
175 INT153657 PRKCA Negative_regulation of MED23 1 0.01 0.22 0.46
176 INT110476 EDN1 Positive_regulation of Localization of PRKCZ 1 0.25 0.07 0.46
177 INT110475 EDN1 Regulation of PRKCA 1 0.05 0.07 0.45
178 INT244050 Binding of Gnb2l1 and Prkca 1 0.01 0 0.45
179 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44
180 INT191896 Pbsn Positive_regulation of Prkca 1 0.04 0.85 0.44
181 INT91087 SST Positive_regulation of Positive_regulation of Prkcg 1 0.29 0.05 0.43
182 INT74548 Prkcg Regulation of Tecr 1 0.48 0 0.43
183 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
184 INT196881 Ly6 Positive_regulation of Prkca 2 0.01 0.25 0.42
185 INT319308 Socs4 Positive_regulation of Prkca 1 0.05 0.67 0.41
186 INT69851 Prkcg Regulation of Pigm 1 0.16 0 0.41
187 INT189681 Negative_regulation of PRKCA Negative_regulation of Gene_expression of METTL3 1 0.00 0.16 0.41
188 INT157650 Phosphorylation of Prkcc Positive_regulation of Pik3c3 1 0.51 0 0.41
189 INT157646 Positive_regulation of Oprd1 Positive_regulation of Phosphorylation of Prkcc 1 0.01 0 0.4
190 INT189689 CHKB Negative_regulation of Positive_regulation of PRKCA 1 0.11 0 0.4
191 INT124799 PRKCA Positive_regulation of Localization of ADCY6 1 0.19 0 0.4
192 INT238384 Tlr4 Positive_regulation of Prkca 1 0.06 0.81 0.4
193 INT157649 Prkcc Regulation of Pik3c3 1 0.30 0 0.39
194 INT235860 Prkca Regulation of Akap5 1 0.16 0 0.39
195 INT124798 RAF1 Regulation of PRKCA 1 0.06 0 0.39
196 INT306693 Prkca Regulation of Positive_regulation of Nav1 1 0.10 0.06 0.39
197 INT244046 Binding of Gabrg1 and Prkca 1 0.06 0 0.39
198 INT153052 Prkcg Positive_regulation of Phosphorylation of Trpv1 1 0.45 0 0.38
199 INT12767 Ins1 Positive_regulation of Phosphorylation of Prkcg 1 0.36 0 0.38
200 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein kinase C activity. They are ordered first by their pain relevance and then by number of times they were reported in protein kinase C activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
2 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
3 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
4 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
5 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
6 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
7 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
8 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
9 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
10 INT48718 Positive_regulation of PRKCA 109 0.69 36.16 46.49
11 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
12 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
13 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
14 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
15 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
16 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
17 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
18 INT52712 Negative_regulation of PRKCA 64 0.57 23.11 28.43
19 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
20 INT117527 Binding of Prkca 25 0.48 6.43 21.05
21 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41
22 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
23 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
24 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
25 INT79458 Localization of Prkca 30 0.81 11.13 15.78
26 INT61172 Gene_expression of PRKCA 34 0.77 8.89 15.47
27 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
28 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
29 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66
30 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
31 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
32 INT72221 Localization of PRKCA 17 0.81 1.23 11.47
33 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
34 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
35 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
36 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
37 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78
38 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
39 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42
40 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31
41 INT75526 Positive_regulation of Positive_regulation of PRKCA 16 0.50 4.34 7.46
42 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13
43 INT110104 Localization of Prkce 17 0.79 3.75 6.92
44 INT72222 Positive_regulation of Localization of PRKCA 8 0.70 0.55 6.56
45 INT118151 Positive_regulation of Prkcz 5 0.12 2.35 6.41
46 INT115849 Localization of Prkcc 5 0.77 0.65 6.26
47 INT127237 Phosphorylation of Prkcc 7 0.81 0 5.96
48 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
49 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
50 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
51 INT59879 Transcription of Prkcg 9 0.69 2.29 5.3
52 INT70800 Negative_regulation of Positive_regulation of PRKCA 9 0.34 2.18 5.17
53 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
54 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
55 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
56 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
57 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
58 INT166678 Negative_regulation of Phosphorylation of PRKCA 12 0.38 5.77 4.59
59 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
60 INT148168 Positive_regulation of Localization of Prkcc 4 0.48 0.15 4.03
61 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
62 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
63 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
64 INT65210 Positive_regulation of Binding of Prkcg 6 0.70 2.71 3.65
65 INT74374 Negative_regulation of Phosphorylation of Prkcg 7 0.41 1.28 3.57
66 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
67 INT109840 Localization of Prkce 5 0.74 3.01 3.45
68 INT129752 Regulation of Phosphorylation of Prkcg 8 0.31 1.43 3.41
69 INT72216 Regulation of Positive_regulation of PRKCA 9 0.37 1.36 3.26
70 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
71 INT53495 Negative_regulation of Negative_regulation of PRKCA 4 0.42 2.37 3.18
72 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
73 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
74 INT161863 Positive_regulation of Regulation of Prkcg 4 0.27 1.63 3.1
75 INT130616 Positive_regulation of Negative_regulation of Prkcg 5 0.48 1.6 3.08
76 INT181668 Protein_catabolism of Prkcg 8 0.77 2.59 3.06
77 INT94687 Binding of Prkcc 5 0.37 0.34 3.02
78 INT95779 Positive_regulation of Gene_expression of Prkcc 5 0.69 5.66 3.02
79 INT118156 Binding of Prkcz 2 0.08 2.68 2.89
80 INT59878 Negative_regulation of Transcription of Prkcg 3 0.43 2.15 2.85
81 INT59877 Regulation of Regulation of Prkcg 2 0.45 1.17 2.81
82 INT171682 Positive_regulation of Phosphorylation of PRKCA 3 0.43 1.04 2.72
83 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
84 INT63846 Gene_expression of Prkcq 1 0.73 1.11 2.58
85 INT122424 Gene_expression of Prkci 1 0.58 0 2.56
86 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
87 INT148166 Positive_regulation of Phosphorylation of Prkcc 2 0.68 0 2.44
88 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
89 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
90 INT122423 Negative_regulation of Gene_expression of Prkci 1 0.43 0 2.04
91 INT124052 Binding of Prkce 2 0.06 2.52 2.03
92 INT70174 Negative_regulation of Regulation of Prkcg 3 0.42 0.88 1.98
93 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
94 INT106636 Binding of PRKCA 7 0.28 3.06 1.93
95 INT48850 Gene_expression of PKN1 16 0.52 1.93 1.92
96 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
97 INT109059 Gene_expression of PRKCZ 2 0.65 0.64 1.87
98 INT79569 Protein_catabolism of PRKCA 3 1.00 0.44 1.78
99 INT135332 Positive_regulation of Negative_regulation of Prkcc 1 0.46 0.74 1.75
100 INT97571 Positive_regulation of Gene_expression of PRKCA 13 0.43 1.61 1.7
101 INT118149 Positive_regulation of Binding of Prkcz 1 0.09 0.58 1.54
102 INT118150 Positive_regulation of Positive_regulation of Prkcz 1 0.08 0.49 1.42
103 INT52713 Regulation of Negative_regulation of PRKCA 5 0.36 1.23 1.41
104 INT121297 Positive_regulation of Positive_regulation of Prkcc 1 0.50 0 1.38
105 INT183568 Negative_regulation of Protein_catabolism of Prkcg 2 0.36 1.12 1.33
106 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
107 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
108 INT63849 Regulation of Gene_expression of Prkcq 1 0.58 0.62 1.24
109 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
110 INT60756 Gene_expression of Prkd1 2 0.58 0.14 1.23
111 INT63847 Regulation of Prkcq 1 0.42 0.5 1.23
112 INT220763 Regulation of Phosphorylation of PRKCA 3 0.29 0.84 1.22
113 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
114 INT63856 Positive_regulation of Gene_expression of Prkcq 1 0.47 0.53 1.16
115 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
116 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
117 INT163914 Positive_regulation of Prkcd 1 0.67 1.43 1.12
118 INT154041 Negative_regulation of Localization of Prkcc 1 0.42 0.3 1.1
119 INT153563 Negative_regulation of Phosphorylation of Prkcc 2 0.42 0 1.04
120 INT122421 Phosphorylation of Prkci 1 0.47 0 1.02
121 INT122141 Binding of Prkd1 4 0.27 0.66 1
122 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
123 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
124 INT182594 Regulation of Protein_catabolism of Prkcg 1 0.39 0 0.88
125 INT167763 Negative_regulation of Prkcz 1 0.04 0.32 0.88
126 INT89669 Negative_regulation of Positive_regulation of Prkcq 1 0.08 0.23 0.87
127 INT317485 Regulation of Binding of Prkca 1 0.17 0.17 0.87
128 INT89668 Positive_regulation of Prkcq 1 0.09 0.22 0.86
129 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
130 INT109060 Regulation of Gene_expression of PRKCZ 1 0.03 0 0.83
131 INT48851 Positive_regulation of Gene_expression of PKN1 2 0.27 0.67 0.78
132 INT265156 Regulation of Binding of Prkcg 1 0.15 0.18 0.78
133 INT79568 Regulation of Protein_catabolism of PRKCA 1 0.45 0.1 0.76
134 INT85349 Negative_regulation of Localization of PRKCA 1 0.09 0 0.74
135 INT82366 Positive_regulation of Protein_catabolism of PRKCA 1 0.49 0 0.73
136 INT87606 Regulation of Prkcc 2 0.43 1.05 0.72
137 INT153565 Gene_expression of PRKCI 1 0.75 0 0.72
138 INT121296 Negative_regulation of Positive_regulation of Prkcc 1 0.58 0 0.72
139 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
140 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
141 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
142 INT280801 Positive_regulation of Transcription of Prkcg 1 0.07 0.12 0.67
143 INT94211 Positive_regulation of Negative_regulation of Prkca 1 0.43 0 0.67
144 INT114405 Regulation of Pkn1 1 0.44 1.58 0.61
145 INT79459 Protein_catabolism of Prkca 2 1.00 0.09 0.6
146 INT153568 Binding of PRKCI 1 0.36 0 0.6
147 INT156528 Negative_regulation of Gene_expression of Prkcc 1 0.36 1.91 0.59
148 INT122420 Regulation of Prkci 1 0.44 0 0.58
149 INT152068 Regulation of Gene_expression of Prkce 1 0.05 0.74 0.56
150 INT172310 Positive_regulation of PKN1 6 0.12 2 0.51
151 INT87608 Positive_regulation of Regulation of Prkcc 1 0.45 0.9 0.49
152 INT136942 Negative_regulation of Positive_regulation of Prkce 1 0.39 0.66 0.48
153 INT63850 Negative_regulation of Prkcq 1 0.40 0 0.46
154 INT286550 Negative_regulation of Prkd1 4 0.42 3.68 0.45
155 INT110477 Positive_regulation of Localization of PRKCZ 1 0.20 0.07 0.45
156 INT110479 Localization of PRKCZ 1 0.35 0.07 0.43
157 INT122140 Negative_regulation of Gene_expression of Prkd1 1 0.03 0.09 0.37
158 INT110478 Regulation of PRKCZ 1 0.20 0.1 0.37
159 INT76855 Negative_regulation of Gene_expression of PRKCA 4 0.30 1.8 0.36
160 INT37246 Positive_regulation of Prkd1 1 0.49 0 0.35
161 INT66060 Regulation of Gene_expression of PKN1 1 0.23 0 0.3
162 INT122142 Positive_regulation of Gene_expression of Prkd1 1 0.05 0.06 0.3
163 INT287251 Negative_regulation of PKN1 6 0.01 1.86 0.25
164 INT286538 Gene_expression of Prkd1 7 0.56 3.97 0.24
165 INT139053 Phosphorylation of PRKCB 1 0.04 0.32 0.23
166 INT139051 Positive_regulation of Phosphorylation of PRKCB 1 0.02 0.33 0.23
167 INT122137 Phosphorylation of Prkd1 1 0.06 0.09 0.23
168 INT139054 Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.33 0.23
169 INT140351 Binding of Prkce 2 0.28 0.32 0.22
170 INT169685 Regulation of Positive_regulation of Prkce 1 0.61 0.36 0.22
171 INT181674 Positive_regulation of Protein_catabolism of Prkcg 1 0.14 0.37 0.21
172 INT282798 Binding of Prkd1 2 0.18 2.11 0.19
173 INT144005 Negative_regulation of PRKCB 2 0.28 0.2 0.19
174 INT341785 Regulation of Localization of PRKCA 1 0.08 0 0.19
175 INT233130 Regulation of PKN1 2 0.02 0.69 0.18
176 INT286532 Localization of Prkd1 3 0.58 3.02 0.16
177 INT286548 Positive_regulation of Prkd1 7 0.36 4.35 0.15
178 INT287249 Localization of PKN1 3 0.03 0.78 0.14
179 INT76856 Negative_regulation of Transcription of PRKCA 1 0.30 0.08 0.13
180 INT76859 Transcription of PRKCA 1 0.49 0.08 0.13
181 INT227120 Transcription of Prkca 2 0.59 0.51 0.1
182 INT269369 Regulation of Gene_expression of PRKCA 1 0.12 0 0.1
183 INT144004 Positive_regulation of PRKCB 1 0.45 0 0.1
184 INT144003 Gene_expression of PRKCB 1 0.39 0 0.08
185 INT352723 Regulation of Localization of Prkd1 1 0.33 0.42 0.08
186 INT209184 Regulation of PRKCI 1 0.02 0.06 0.06
187 INT286535 Regulation of Prkd1 3 0.33 2.24 0.04
188 INT267192 Localization of Prkcd 1 0.78 0.96 0.03
189 INT267186 Positive_regulation of Localization of Prkcd 1 0.49 0.97 0.03
190 INT222851 Binding of Pkn1 4 0.03 0.1 0
191 INT233129 Binding of PKN1 3 0.03 0 0
192 INT286534 Negative_regulation of Gene_expression of Prkd1 2 0.31 0.89 0
193 INT97092 Positive_regulation of Negative_regulation of PRKCA 2 0.27 0.31 0
194 INT327869 Positive_regulation of Pkn1 1 0.04 0.32 0
195 INT185445 Binding of PRKCB 1 0.23 0.99 0
196 INT318844 Binding of PKN3 1 0.03 0 0
197 INT318840 Gene_expression of PKN3 1 0.05 0 0
198 INT352729 Negative_regulation of Regulation of Prkd1 1 0.31 0.08 0
199 INT183569 Negative_regulation of Binding of Prkcg 1 0.05 0.69 0
200 INT269598 Regulation of Positive_regulation of PKN1 1 0.07 0 0
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