GO:0004698

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Name calcium-dependent protein kinase C activity
Categary Function
Go Slim No
Go Link GO:0004698
Unique Molecular Interactions 672
Total Molecular Interactions 908
Total Single Events 9070
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for calcium-dependent protein kinase C activity. They are ordered first by their pain relevance and then by number of times they were reported for calcium-dependent protein kinase C activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36
2 INT145775 Ngf Positive_regulation of Trpv1 11 0.72 7.71 11.25
3 INT251170 Clu Positive_regulation of Trpv1 1 0.28 2.61 6.49
4 INT122779 Ngf Positive_regulation of Gene_expression of Trpv1 8 0.74 4.31 6.1
5 INT351352 Binding of Trpv1 and Lpar1 1 0.21 5.86 4.62
6 INT180774 Gdnf Positive_regulation of Trpv1 1 0.33 2.43 4.37
7 INT130625 Prkcg Regulation of Prkaca 1 0.23 1.32 3.87
8 INT122349 Ngf Regulation of Trpv1 3 0.64 1.55 3.79
9 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
10 INT141254 Ngf Regulation of Transcription of Trpv1 1 0.53 1.37 3.74
11 INT115690 Negative_regulation of Prkcg Negative_regulation of Gene_expression of Fos 1 0.47 0.72 3.63
12 INT158770 Binding of Trpv1 and Trpa1 5 0.34 2.07 3.5
13 INT195931 Binding of OPRM1 and Trpv1 1 0.07 0.87 3.43
14 INT276676 Prkcg Regulation of Nav1 1 0.30 0.82 3.29
15 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
16 INT122780 Ngf Regulation of Gene_expression of Trpv1 4 0.65 3.74 3.11
17 INT161164 Prkcg Regulation of Phosphorylation of Creb1 3 0.41 0.62 3.11
18 INT276679 Prkcg Positive_regulation of Positive_regulation of Nkx1-1 1 0.07 0.94 3.08
19 INT122776 Gdnf Positive_regulation of Gene_expression of Trpv1 2 0.67 2.13 3.06
20 INT118158 Binding of Prkca and Prkcz 1 0.07 1.14 2.98
21 INT351349 Prkcg Positive_regulation of Binding of Lpar1 1 0.15 2 2.82
22 INT182564 Binding of Ptger2 and Trpv1 1 0.18 1.77 2.67
23 INT167769 Prkca Positive_regulation of Positive_regulation of Sigmar1 1 0.38 0.86 2.63
24 INT121742 Prkcg Positive_regulation of Ephb1 3 0.49 0.99 2.6
25 INT210696 Trpv1 Regulation of Slc12a2 1 0.25 1.97 2.58
26 INT122775 Gdnf Regulation of Gene_expression of Trpv1 4 0.59 2.72 2.42
27 INT107165 Binding of Gabrg1 and Trpv1 2 0.01 0.16 2.34
28 INT228454 Ngf Positive_regulation of Phosphorylation of Trpv1 1 0.39 2.97 2.26
29 INT251164 Binding of Clu and Trpv1 1 0.19 0.44 2.23
30 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18
31 INT167530 Phax Regulation of Gene_expression of Trpv1 1 0.16 0.86 2.05
32 INT121216 Prkca Regulation of Positive_regulation of Oprd1 1 0.02 0.32 2.02
33 INT144115 Positive_regulation of Grm5 Positive_regulation of Prkcg 1 0.41 0 2.01
34 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
35 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92
36 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9
37 INT186435 Prkcg Regulation of Creb1 1 0.44 0.45 1.9
38 INT161079 Mcs18 Negative_regulation of Trpv1 1 0.40 0.82 1.9
39 INT166945 Ngf Positive_regulation of Trpv1 1 0.01 0.47 1.88
40 INT338691 Binding of Trpv1 and Aff3 1 0.24 1.21 1.88
41 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
42 INT276669 Negative_regulation of Prkcg Regulation of Nav1 1 0.21 0.68 1.82
43 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
44 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
45 INT23392 Gal Regulation of Trpv1 1 0.05 0.33 1.77
46 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
47 INT167765 Prkca Positive_regulation of Sigmar1 1 0.41 0.63 1.74
48 INT182565 Ptger2 Regulation of Trpv1 1 0.25 1.34 1.73
49 INT134363 Prkcg Regulation of ADCY2 1 0.00 0.14 1.7
50 INT276672 Binding of Prkcg and Nav1 1 0.16 0.18 1.67
51 INT139433 Binding of Prkaca and Prkca 1 0.37 0.13 1.67
52 INT276680 Binding of Prkcg and Nkx1-1 1 0.05 0.18 1.66
53 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
54 INT276670 Binding of Trpv1 and Nkx1-1 1 0.07 0.68 1.6
55 INT136034 Edn1 Regulation of Trpv1 2 0.66 0.39 1.58
56 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
57 INT276671 Prkcg Positive_regulation of Nav1 1 0.23 0.21 1.55
58 INT121747 Prkcg Negative_regulation of Positive_regulation of Creb1 1 0.16 0.2 1.5
59 INT42000 Trpv1 Positive_regulation of Cck 1 0.04 0 1.49
60 INT41999 Trpv1 Positive_regulation of Vip 1 0.04 0 1.49
61 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
62 INT136844 Binding of Prkca and Nrgn 1 0.33 0 1.47
63 INT161870 OPRM1 Positive_regulation of Prkcg 1 0.01 0.12 1.47
64 INT161865 Mors1 Positive_regulation of Prkcg 1 0.00 0.12 1.47
65 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44
66 INT153581 Binding of Oprm1 and Prkcg 1 0.00 0 1.44
67 INT221242 Ros1 Positive_regulation of Prkca 1 0.02 0.39 1.44
68 INT180789 Ngf Regulation of Localization of Trpv1 1 0.28 1.22 1.44
69 INT180768 Bdnf Regulation of Localization of Trpv1 1 0.13 1.21 1.43
70 INT180790 Gdnf Regulation of Localization of Trpv1 1 0.15 1.21 1.43
71 INT78974 Binding of Prkcg and Prkaca 2 0.31 0.35 1.4
72 INT144123 Binding of P2rx6 and Trpv1 1 0.11 0 1.4
73 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38
74 INT167529 Ppt1 Negative_regulation of Gene_expression of Trpv1 1 0.26 0.49 1.38
75 INT182558 Binding of Ptgir and Trpv1 1 0.16 1.12 1.37
76 INT276673 Nkx1-1 Regulation of Trpv1 1 0.05 0.16 1.37
77 INT261483 Binding of Ephb1 and Trpv1 1 0.39 1.37 1.37
78 INT355248 Ltp Positive_regulation of Localization of Trpv1 1 0.51 0 1.35
79 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
80 INT131888 gr Positive_regulation of Gene_expression of Prkcg 1 0.00 0 1.32
81 INT120929 Prkcg Regulation of Gene_expression of Fos 2 0.50 0.34 1.31
82 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
83 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
84 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
85 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29
86 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28
87 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
88 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
89 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
90 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
91 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
92 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
93 INT93294 Ngf Regulation of Transcription of Trpv1 1 0.01 0.36 1.19
94 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
95 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
96 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
97 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
98 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
99 INT121725 Binding of Trpv1 and Pik3cb 1 0.35 0.62 1.15
100 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
101 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13
102 INT121362 Trpv1 Regulation of Localization of Ins1 1 0.51 0.17 1.12
103 INT130471 Prkcg Regulation of Regulation of Fos 1 0.45 0.27 1.12
104 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12
105 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11
106 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1
107 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1
108 INT121730 Pik3cb Regulation of Trpv1 1 0.58 0.54 1.09
109 INT305734 Binding of Sort1 and Trpv1 1 0.01 0.5 1.08
110 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
111 INT154846 Negative_regulation of Mapk14 Negative_regulation of Positive_regulation of Trpv1 1 0.23 0.07 1.05
112 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
113 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
114 INT114553 Binding of Trpv1 and Col4a4 1 0.01 0.44 1.03
115 INT114554 Binding of St3gal3 and Trpv1 1 0.01 0.44 1.03
116 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
117 INT240453 Prkcg Positive_regulation of Positive_regulation of Prkaca 1 0.23 0.63 1.01
118 INT148327 Binding of Pkd1 and Trpv1 1 0.52 2.23 1.01
119 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
120 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1
121 INT283932 Positive_regulation of Mapk14 Regulation of Gene_expression of Trpv1 1 0.14 1.28 0.99
122 INT307100 Trpv1 Regulation of Binding of Trpa1 1 0.31 1.81 0.97
123 INT307103 Trpa1 Regulation of Binding of Trpv1 1 0.31 1.81 0.97
124 INT211745 Gnptab Regulation of Positive_regulation of Prkca 1 0.00 0 0.96
125 INT122144 Binding of Trpv1 and Prkd1 1 0.02 0.39 0.96
126 INT152084 Edn1 Negative_regulation of Positive_regulation of Trpv1 1 0.62 0.48 0.96
127 INT156608 Trpv1 Regulation of Nav1 1 0.51 0.52 0.95
128 INT136033 Edn1 Positive_regulation of Trpv1 1 0.50 0.34 0.95
129 INT144902 Binding of Trpv1 and Pars2 1 0.17 0 0.95
130 INT123051 Gpbar1 Regulation of Phosphorylation of Prkca 1 0.43 0 0.94
131 INT199396 Prok2 Regulation of Trpv1 1 0.43 1.23 0.94
132 INT123050 Prkca Regulation of Phosphorylation of Grk4 1 0.33 0 0.94
133 INT123048 Grk4 Regulation of Phosphorylation of Prkca 1 0.33 0 0.94
134 INT123053 Prkca Regulation of Phosphorylation of Gpbar1 1 0.43 0 0.94
135 INT78976 Prkcg Regulation of Ina 1 0.13 0.16 0.93
136 INT159996 Prkcg Regulation of Gene_expression of App 1 0.42 0.32 0.92
137 INT195927 Binding of Prkaca and Trpv1 1 0.07 0.28 0.92
138 INT159994 App Regulation of Gene_expression of Prkcg 1 0.42 0.32 0.92
139 INT159995 Prkcg Regulation of Gene_expression of Bace1 1 0.39 0.32 0.91
140 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
141 INT85783 PRKG1 Regulation of Prkcg 1 0.09 0.38 0.9
142 INT180772 Bdnf Regulation of Trpv1 1 0.11 0.29 0.9
143 INT180777 Bdnf Regulation of Gene_expression of Trpv1 1 0.18 0.29 0.9
144 INT12766 Ins1 Positive_regulation of Prkcg 3 0.53 0.07 0.89
145 INT167771 Prkca Positive_regulation of Phosphorylation of Sigmar1 1 0.38 0.23 0.89
146 INT113383 Negative_regulation of Sert1 Positive_regulation of Prkcg 1 0.31 0 0.89
147 INT326455 Runx1 Positive_regulation of Gene_expression of Trpv1 1 0.45 0 0.88
148 INT251159 Binding of Clu and Positive_regulation of Trpv1 1 0.16 0 0.87
149 INT152835 Prkcg Regulation of Phosphorylation of Nfasc 1 0.10 0.21 0.87
150 INT152853 Prkcg Regulation of PRS 1 0.01 0.21 0.87
151 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87
152 INT80792 Prkcg Regulation of Oprd1 1 0.19 0.2 0.86
153 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
154 INT222243 Negative_regulation of Binding of Trpv1 and Ccr5 1 0.21 0.57 0.86
155 INT222244 Binding of Trpv1 and Ccr5 1 0.19 0.57 0.86
156 INT193278 Brs3 Positive_regulation of Gene_expression of Trpv1 1 0.04 0.09 0.86
157 INT114546 Ins1 Positive_regulation of Positive_regulation of Trpv1 1 0.39 0.19 0.86
158 INT182555 Ptgir Regulation of Trpv1 1 0.12 0.61 0.85
159 INT338695 CAP1 Regulation of Trpv1 1 0.01 0.14 0.85
160 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84
161 INT80793 Prkcg Regulation of Pkm2 1 0.29 0.2 0.83
162 INT152083 Binding of Edn1 and Trpv1 1 0.38 0.67 0.83
163 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82
164 INT190869 Binding of Prkca and Ltp 1 0.03 0.86 0.81
165 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
166 INT124292 Binding of Trpv1 and F2rl1 1 0.46 1.1 0.81
167 INT157913 Trpv1 Regulation of Gene_expression of Edn1 1 0.29 0.55 0.81
168 INT251172 Trpv1 Regulation of Gene_expression of Ca2 1 0.13 0.7 0.81
169 INT157915 Prkca Regulation of Gene_expression of Edn1 1 0.17 0.55 0.81
170 INT282063 Ngf Positive_regulation of Positive_regulation of Prkca 1 0.09 0.18 0.8
171 INT219911 Edn1 Regulation of Gene_expression of Trpv1 1 0.23 0.57 0.8
172 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8
173 INT192134 Ngf Positive_regulation of Trpv1 1 0.18 1.22 0.79
174 INT125353 Binding of Sst and Trpv1 1 0.36 0.5 0.79
175 INT240456 Ephb1 Regulation of Prkcg 1 0.19 0.51 0.79
176 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79
177 INT107739 Prkcg Negative_regulation of Positive_regulation of Pld2 1 0.46 0 0.79
178 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78
179 INT157914 Trpv1 Regulation of Prkca 1 0.07 0.55 0.78
180 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78
181 INT157917 TRPV1 Regulation of Prkca 1 0.04 0.55 0.78
182 INT145430 oh Positive_regulation of Trpv1 1 0.05 0.15 0.78
183 INT351364 LPA Positive_regulation of Trpv1 1 0.02 1.15 0.78
184 INT152833 Nefl Regulation of Prkcg 1 0.12 0.19 0.77
185 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77
186 INT152831 Nefh Regulation of Prkcg 1 0.05 0.19 0.77
187 INT190867 Binding of Marcks and Prkca 1 0.17 0.8 0.77
188 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
189 INT152836 Nefm Regulation of Prkcg 1 0.15 0.19 0.77
190 INT114547 Ins1 Positive_regulation of Trpv1 1 0.36 0.19 0.77
191 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
192 INT94816 Prkcg Positive_regulation of TACR1 1 0.06 0.1 0.76
193 INT108671 Positive_regulation of ras Positive_regulation of Positive_regulation of Trpv1 1 0.04 0.26 0.76
194 INT276865 Regulation of Trpv1 Regulation of Gene_expression of Gpr65 1 0.25 0.62 0.76
195 INT159689 Trpv4 Negative_regulation of Trpv1 1 0.36 0.41 0.76
196 INT278490 Negative_regulation of Faah Positive_regulation of Trpv1 1 0.38 0.6 0.76
197 INT152854 PRS Regulation of Prkcg 1 0.01 0.19 0.76
198 INT193276 Brs3 Negative_regulation of Gene_expression of Trpv1 1 0.03 0.14 0.75
199 INT129557 Binding of Trpv2 and Trpv1 1 0.41 0.18 0.74
200 INT185140 Elane Positive_regulation of Prkca 1 0.00 0 0.74

Single Events

The table below shows the top 100 pain related interactions that have been reported for calcium-dependent protein kinase C activity. They are ordered first by their pain relevance and then by number of times they were reported in calcium-dependent protein kinase C activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59
2 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42
3 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42
4 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41
5 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59
6 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47
7 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4
8 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91
9 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75
10 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44
11 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03
12 INT38731 Localization of Trpv1 138 0.81 52.73 90.49
13 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63
14 INT64158 Negative_regulation of Prkca 121 0.59 29.8 88.66
15 INT4830 Binding of Trpv1 158 0.48 45.11 84.2
16 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7
17 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23
18 INT12536 Localization of Prkcg 101 0.80 36.37 73.81
19 INT87686 Positive_regulation of Gene_expression of Trpv1 101 0.70 72.41 69.15
20 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17
21 INT96622 Localization of Trpv1 110 0.81 59.82 63.25
22 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97
23 INT98498 Binding of Trpv1 75 0.48 33.67 44.4
24 INT57442 Phosphorylation of Prkca 98 0.70 31.58 41.04
25 INT58062 Negative_regulation of Gene_expression of Trpv1 66 0.59 22.34 38.02
26 INT80075 Regulation of Gene_expression of Trpv1 55 0.62 32.42 36.88
27 INT48959 Positive_regulation of Positive_regulation of Prkcg 52 0.70 16.47 36.49
28 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77
29 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67
30 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28
31 INT12537 Positive_regulation of Localization of Prkcg 36 0.70 14.57 33.81
32 INT51698 Positive_regulation of Gene_expression of Prkcg 44 0.68 14.02 32.9
33 INT64164 Regulation of Prkca 34 0.62 10.44 30.99
34 INT9133 Negative_regulation of Positive_regulation of Prkcg 37 0.59 10.95 30.06
35 INT112036 Phosphorylation of Trpv1 51 0.82 18.59 25.6
36 INT103320 Positive_regulation of Positive_regulation of Trpv1 44 0.70 27.73 25.28
37 INT92105 Transcription of Trpv1 47 0.71 27.47 25.01
38 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2
39 INT87607 Positive_regulation of Prkcc 25 0.69 6.06 22.78
40 INT89056 Phosphorylation of Trpv1 46 0.82 13.52 22.16
41 INT117527 Binding of Prkca 25 0.48 6.43 21.05
42 INT96511 Negative_regulation of Positive_regulation of Trpv1 35 0.59 10.95 19.79
43 INT90937 Negative_regulation of Gene_expression of Trpv1 34 0.59 22.74 18.12
44 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
45 INT65211 Binding of Prkcg 38 0.48 14.75 16.92
46 INT74545 Negative_regulation of Gene_expression of Prkcg 22 0.42 7.77 16.26
47 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18
48 INT79458 Localization of Prkca 30 0.81 11.13 15.78
49 INT79887 Gene_expression of Prkcc 20 0.78 12.59 14.73
50 INT63854 Regulation of Gene_expression of Prkcg 27 0.56 9.41 14.15
51 INT97848 Positive_regulation of Localization of Trpv1 18 0.50 7.66 13.36
52 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36
53 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
54 INT101494 Regulation of Positive_regulation of Trpv1 18 0.62 6.57 12.9
55 INT47847 Negative_regulation of Localization of Prkcg 11 0.58 4.02 12.36
56 INT145515 Positive_regulation of Localization of Trpv1 23 0.50 10.12 12.08
57 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
58 INT112037 Negative_regulation of Positive_regulation of Trpv1 19 0.59 8.9 10.55
59 INT112940 Negative_regulation of Positive_regulation of Prkca 12 0.45 5.85 10
60 INT102865 Positive_regulation of Positive_regulation of Prkca 25 0.69 8.34 9.9
61 INT79248 Regulation of Negative_regulation of Prkcg 13 0.44 3.44 9.78
62 INT47845 Regulation of Localization of Prkcg 16 0.62 3.1 9.42
63 INT89053 Positive_regulation of Phosphorylation of Trpv1 16 0.70 8.89 9.39
64 INT71565 Negative_regulation of Prkcc 11 0.54 4.16 9.31
65 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
66 INT79247 Negative_regulation of Negative_regulation of Prkcg 11 0.42 1.78 7.13
67 INT115849 Localization of Prkcc 5 0.77 0.65 6.26
68 INT103319 Regulation of Positive_regulation of Trpv1 11 0.45 8.37 5.99
69 INT127237 Phosphorylation of Prkcc 7 0.81 0 5.96
70 INT125187 Positive_regulation of Transcription of Trpv1 9 0.69 8.98 5.77
71 INT123045 Negative_regulation of Phosphorylation of Prkca 9 0.46 5.73 5.77
72 INT59879 Transcription of Prkcg 9 0.69 2.29 5.3
73 INT94357 Positive_regulation of Transcription of Trpv1 11 0.50 3.63 5.05
74 INT57441 Positive_regulation of Phosphorylation of Prkca 9 0.40 2.72 4.89
75 INT83205 Negative_regulation of Negative_regulation of Prkca 6 0.43 1.14 4.87
76 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
77 INT134610 Positive_regulation of Phosphorylation of Trpv1 9 0.69 4.51 4.74
78 INT64160 Negative_regulation of Gene_expression of Prkca 8 0.43 3.01 4.72
79 INT79460 Positive_regulation of Localization of Prkca 11 0.70 2.72 4.71
80 INT153269 Binding of Ccl3 10 0.48 8.87 4.69
81 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
82 INT148168 Positive_regulation of Localization of Prkcc 4 0.48 0.15 4.03
83 INT76466 Regulation of Gene_expression of Prkca 6 0.45 0.94 3.91
84 INT144083 Positive_regulation of Gene_expression of Ccl3 10 0.50 8.16 3.81
85 INT118154 Positive_regulation of Binding of Prkca 2 0.50 0.58 3.81
86 INT154225 Negative_regulation of Binding of Prkca 2 0.30 0.06 3.71
87 INT64203 Positive_regulation of Negative_regulation of Trpv1 5 0.47 3.39 3.67
88 INT65210 Positive_regulation of Binding of Prkcg 6 0.70 2.71 3.65
89 INT141253 Regulation of Transcription of Trpv1 7 0.62 3.54 3.62
90 INT74374 Negative_regulation of Phosphorylation of Prkcg 7 0.41 1.28 3.57
91 INT83206 Regulation of Regulation of Prkca 3 0.45 1.34 3.46
92 INT129752 Regulation of Phosphorylation of Prkcg 8 0.31 1.43 3.41
93 INT181357 Negative_regulation of Ccl3 12 0.59 13.09 3.38
94 INT118153 Regulation of Positive_regulation of Prkca 5 0.45 3.15 3.23
95 INT58063 Negative_regulation of Binding of Trpv1 6 0.59 1.54 3.21
96 INT138350 Regulation of Phosphorylation of Trpv1 6 0.58 1.87 3.16
97 INT190860 Regulation of Localization of Prkca 4 0.21 1.61 3.11
98 INT161863 Positive_regulation of Regulation of Prkcg 4 0.27 1.63 3.1
99 INT130616 Positive_regulation of Negative_regulation of Prkcg 5 0.48 1.6 3.08
100 INT181668 Protein_catabolism of Prkcg 8 0.77 2.59 3.06
101 INT94687 Binding of Prkcc 5 0.37 0.34 3.02
102 INT95779 Positive_regulation of Gene_expression of Prkcc 5 0.69 5.66 3.02
103 INT196872 Negative_regulation of Localization of Trpv1 4 0.42 1.47 2.98
104 INT114263 Negative_regulation of Negative_regulation of Trpv1 6 0.43 2.71 2.92
105 INT59878 Negative_regulation of Transcription of Prkcg 3 0.43 2.15 2.85
106 INT59877 Regulation of Regulation of Prkcg 2 0.45 1.17 2.81
107 INT118888 Regulation of Localization of Trpv1 5 0.44 1.43 2.64
108 INT125191 Regulation of Transcription of Trpv1 6 0.45 4.54 2.62
109 INT108691 Regulation of Binding of Trpv1 3 0.58 1.91 2.51
110 INT184583 Regulation of Phosphorylation of Prkca 3 0.21 1.76 2.5
111 INT148166 Positive_regulation of Phosphorylation of Prkcc 2 0.68 0 2.44
112 INT71681 Positive_regulation of Gene_expression of CCL3 8 0.54 8.21 2.41
113 INT108395 Positive_regulation of Binding of Trpv1 5 0.50 1.26 2.39
114 INT195917 Regulation of Phosphorylation of Trpv1 2 0.52 1.86 2.29
115 INT262548 Regulation of Localization of Trpv1 2 0.45 0.73 2.25
116 INT116784 Regulation of Regulation of Trpv1 5 0.60 1.76 2.18
117 INT261812 Positive_regulation of Negative_regulation of Trpv1 3 0.46 1.26 2.11
118 INT70174 Negative_regulation of Regulation of Prkcg 3 0.42 0.88 1.98
119 INT102866 Regulation of Negative_regulation of Prkca 2 0.43 1.27 1.95
120 INT170345 Negative_regulation of Localization of Prkca 5 0.23 0.88 1.88
121 INT120014 Transcription of CCL3 5 0.69 3.03 1.82
122 INT126539 Negative_regulation of Transcription of Trpv1 9 0.59 1.52 1.8
123 INT135332 Positive_regulation of Negative_regulation of Prkcc 1 0.46 0.74 1.75
124 INT149510 Negative_regulation of Transcription of Trpv1 5 0.56 3.74 1.5
125 INT330442 Negative_regulation of Regulation of Trpv1 1 0.37 1.69 1.38
126 INT121297 Positive_regulation of Positive_regulation of Prkcc 1 0.50 0 1.38
127 INT183568 Negative_regulation of Protein_catabolism of Prkcg 2 0.36 1.12 1.33
128 INT182548 Regulation of Regulation of Trpv1 1 0.26 1.52 1.27
129 INT65699 Localization of CCL3 7 0.78 2.56 1.25
130 INT123828 Regulation of CCL3 3 0.60 0.79 1.25
131 INT122662 Negative_regulation of Negative_regulation of Trpv1 1 0.59 1.74 1.22
132 INT155676 Positive_regulation of Regulation of Trpv1 2 0.47 0.97 1.17
133 INT153267 Negative_regulation of Binding of Ccl3 2 0.43 2.06 1.14
134 INT154041 Negative_regulation of Localization of Prkcc 1 0.42 0.3 1.1
135 INT181410 Regulation of Gene_expression of Ccl3 2 0.33 3.52 1.06
136 INT153563 Negative_regulation of Phosphorylation of Prkcc 2 0.42 0 1.04
137 INT332476 Protein_catabolism of Trpv1 1 0.65 0.1 1.02
138 INT166880 Negative_regulation of Gene_expression of Ccl3 1 0.57 0.81 1.01
139 INT152082 Negative_regulation of Phosphorylation of Trpv1 2 0.43 0.28 0.95
140 INT202174 Negative_regulation of CCL3 2 0.26 1.77 0.9
141 INT79235 Binding of CCL3 3 0.36 2.2 0.88
142 INT182594 Regulation of Protein_catabolism of Prkcg 1 0.39 0 0.88
143 INT317485 Regulation of Binding of Prkca 1 0.17 0.17 0.87
144 INT153272 Positive_regulation of Localization of Ccl3 2 0.50 2.02 0.79
145 INT265156 Regulation of Binding of Prkcg 1 0.15 0.18 0.78
146 INT160378 Protein_catabolism of Trpv1 2 0.89 0.61 0.73
147 INT87606 Regulation of Prkcc 2 0.43 1.05 0.72
148 INT120013 Negative_regulation of Transcription of CCL3 1 0.41 1 0.72
149 INT121296 Negative_regulation of Positive_regulation of Prkcc 1 0.58 0 0.72
150 INT153270 Positive_regulation of Binding of Ccl3 1 0.47 1.44 0.69
151 INT280801 Positive_regulation of Transcription of Prkcg 1 0.07 0.12 0.67
152 INT94211 Positive_regulation of Negative_regulation of Prkca 1 0.43 0 0.67
153 INT135292 Positive_regulation of Regulation of Trpv1 2 0.43 0.34 0.61
154 INT79459 Protein_catabolism of Prkca 2 1.00 0.09 0.6
155 INT156528 Negative_regulation of Gene_expression of Prkcc 1 0.36 1.91 0.59
156 INT261814 Regulation of Negative_regulation of Trpv1 1 0.23 0.07 0.56
157 INT128360 Negative_regulation of Positive_regulation of Ccl3 2 0.41 1.86 0.55
158 INT221040 Negative_regulation of Gene_expression of CCL3 2 0.20 1.19 0.53
159 INT122138 Negative_regulation of Phosphorylation of Trpv1 3 0.43 0.31 0.52
160 INT87608 Positive_regulation of Regulation of Prkcc 1 0.45 0.9 0.49
161 INT350374 Negative_regulation of Localization of Trpv1 1 0.38 0.14 0.39
162 INT122143 Negative_regulation of Regulation of Trpv1 1 0.18 0.09 0.37
163 INT130584 Positive_regulation of Binding of Trpv1 2 0.64 0.18 0.36
164 INT79236 Positive_regulation of Positive_regulation of CCL3 1 0.49 1.22 0.28
165 INT301314 Regulation of Binding of CCL3 1 0.04 0 0.24
166 INT181399 Transcription of Ccl3 2 0.60 0.41 0.22
167 INT181674 Positive_regulation of Protein_catabolism of Prkcg 1 0.14 0.37 0.21
168 INT230578 Regulation of Negative_regulation of Trpv1 1 0.32 0 0.2
169 INT329819 Phosphorylation of CCL3 1 0.23 0.61 0.17
170 INT285899 Positive_regulation of Localization of CCL3 1 0.12 1.08 0.17
171 INT312718 Protein_catabolism of CCL3 1 0.31 0.44 0.16
172 INT227120 Transcription of Prkca 2 0.59 0.51 0.1
173 INT183569 Negative_regulation of Binding of Prkcg 1 0.05 0.69 0
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