GO:0004722

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Name protein serine/threonine phosphatase activity
Categary Function
Go Slim No
Go Link GO:0004722
Unique Molecular Interactions 271
Total Molecular Interactions 341
Total Single Events 1403
Pain Genes Associated 22

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein serine/threonine phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported for protein serine/threonine phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT162992 Binding of Ephb1 and Ppm1e 1 0.03 0.25 1.77
2 INT100816 PPP1R14C Regulation of Ppp1cc 1 0.08 0 1.27
3 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12
4 INT109374 Ppp1cc Negative_regulation of Ppp2r1a 1 0.24 0 1.11
5 INT320120 MTX1 Positive_regulation of PTEN 1 0.04 0.09 0.82
6 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8
7 INT162995 Positive_regulation of Binding of Ephb1 and Ppm1e 1 0.04 0.06 0.74
8 INT276213 Pten Regulation of Phosphorylation of Akt1 1 0.51 0.61 0.72
9 INT100806 Ppp1r14a Regulation of Ppp1cc 1 0.05 0 0.65
10 INT218837 Ppp1cc Regulation of Ltp 1 0.13 1.19 0.62
11 INT218835 Ppp1cc Regulation of Cysltr1 1 0.01 1.19 0.62
12 INT218833 Binding of Ppp1cc and Regulation of Ltp 1 0.13 1.2 0.62
13 INT218836 Binding of Ppp1cc and Regulation of Cysltr1 1 0.01 1.2 0.62
14 INT218845 Ppp1cc Positive_regulation of Positive_regulation of Cysltr1 1 0.02 0.92 0.6
15 INT162991 Binding of Fadd and Ppm1e 1 0.03 0.09 0.52
16 INT196809 Arpp21 Regulation of Ppp1cc 1 0.01 0 0.52
17 INT196826 Ppp1r1b Regulation of Ppp1cc 1 0.10 0 0.51
18 INT320121 Binding of PTEN and TNF 1 0.05 0.76 0.49
19 INT276218 Binding of Akt1 and Pten 1 0.26 0.08 0.46
20 INT167619 Protein_catabolism of Ppp2cb Positive_regulation of App 1 0.00 0.88 0.44
21 INT160046 INPPL1 Regulation of Gene_expression of PTEN 1 0.41 0.6 0.42
22 INT160047 PTEN Regulation of Gene_expression of AKT1 1 0.33 0.6 0.42
23 INT160049 PTEN Regulation of Gene_expression of INPPL1 1 0.41 0.6 0.42
24 INT121849 CASP8 Positive_regulation of CYCS 1 0.35 0.48 0.4
25 INT121852 CASP8 Positive_regulation of Localization of CYCS 1 0.32 0.48 0.4
26 INT313455 Binding of Ppp2ca and Syp 1 0.45 0.68 0.4
27 INT196828 Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.4
28 INT196800 Trh Negative_regulation of Ppp1cc 1 0.01 0 0.39
29 INT196829 Ppp1r1b Negative_regulation of Phosphorylation of Ppp1cc 1 0.07 0 0.39
30 INT266553 Ppp2r1a Positive_regulation of Fig4 1 0.00 0 0.38
31 INT218843 Binding of Ppp1cc and Ppp1r9a 1 0.17 0.52 0.36
32 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
33 INT176135 AKT1 Regulation of Localization of CYCS 1 0.43 2.16 0.35
34 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
35 INT196820 Negative_regulation of Ppp1cc Positive_regulation of Akt1 1 0.00 0 0.34
36 INT181451 Lck Regulation of Mbp 1 0.08 1.43 0.34
37 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
38 INT235869 Binding of Slc6a4 and Ppp2ca 1 0.04 0.21 0.31
39 INT235872 Phosphorylation of Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.31
40 INT132984 CYP3A4 Positive_regulation of Gene_expression of PPP4C 1 0.44 0 0.3
41 INT218831 Ppp1cc Regulation of Gria2 1 0.27 0.86 0.3
42 INT235886 Ppp2ca Positive_regulation of Slc37a4 1 0.00 0.15 0.3
43 INT196825 Prkaca Positive_regulation of Phosphorylation of Ppp2ca 1 0.20 0 0.29
44 INT196831 Positive_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.20 0 0.29
45 INT196814 Negative_regulation of Prkaca Positive_regulation of Ppp2ca 1 0.17 0 0.29
46 INT218847 Ppp1cc Positive_regulation of Regulation of Ltp 1 0.22 0.46 0.29
47 INT313446 Syp Regulation of Ppp2ca 1 0.58 0.62 0.26
48 INT90280 Binding of Ppp1cc and Ppp2ca 1 0.34 0.22 0.22
49 INT311613 Binding of Slc6a4 and Pten 1 0.24 0.32 0.21
50 INT203848 Binding of Pten and Lna1 1 0.06 0.4 0.2
51 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19
52 INT281477 Binding of Pten and Th 1 0.28 0.4 0.19
53 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
54 INT119265 Binding of CREBBP and PPM1E 1 0.01 0.46 0.17
55 INT313449 Siglec1 Regulation of Ppp2ca 1 0.03 0.61 0.17
56 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
57 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
58 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
59 INT87092 Binding of PPP4C and MBD2 1 0.05 0 0.16
60 INT235883 Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
61 INT65883 Binding of CYP1A1 and PPP4C 1 0.02 0 0.15
62 INT208264 Park7 Negative_regulation of Pten 1 0.16 1.16 0.15
63 INT235879 Regulation of Ppp2ca Regulation of Slc6a4 1 0.03 0 0.15
64 INT244052 Ppp1ca Regulation of Phosphorylation of Gabrg1 1 0.00 0.18 0.14
65 INT130922 HMHA1 Positive_regulation of Protein_catabolism of CYCS 1 0.06 1.39 0.14
66 INT130917 HMHA1 Positive_regulation of CYCS 1 0.06 1.39 0.14
67 INT244051 Ppp1ca Regulation of Prkaca 1 0.00 0.18 0.14
68 INT86551 Ppm1f Positive_regulation of Camk1g 1 0.49 0 0.13
69 INT276037 Binding of Prkaca and Ppp1cc 1 0.08 0 0.12
70 INT276040 Binding of Camk2a and Ppp1cc 1 0.13 0 0.12
71 INT244032 Binding of Ppp1ca and Plcl1 1 0.00 0.16 0.12
72 INT244033 Binding of Gabrg1 and Ppp1ca 1 0.00 0.16 0.12
73 INT171383 Ppp1cc Positive_regulation of Positive_regulation of Mapk1 1 0.18 0 0.11
74 INT196827 Phosphorylation of Prkaca Positive_regulation of Ppp2ca 1 0.18 0 0.11
75 INT256544 Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
76 INT171385 Ppp1cc Positive_regulation of Phosphorylation of Egfr 1 0.15 0 0.11
77 INT196819 Prkaca Positive_regulation of Binding of Ppp2ca 1 0.20 0 0.11
78 INT171387 Ppp1cc Positive_regulation of Phosphorylation of Src 1 0.07 0 0.11
79 INT171392 Ppp1cc Positive_regulation of Phosphorylation of Gpbar1 1 0.06 0 0.11
80 INT256545 Positive_regulation of Pten Negative_regulation of Akt1 1 0.05 1.07 0.11
81 INT133481 TNF Positive_regulation of Phosphorylation of PTEN 1 0.13 0.61 0.09
82 INT313430 Syp Positive_regulation of Ppp2ca 1 0.66 0.08 0.09
83 INT276033 Binding of Ppp1cc and Ppp1r1b 1 0.06 0 0.09
84 INT313447 Ppp2ca Regulation of Phosphorylation of Syp 1 0.43 0 0.08
85 INT313469 Ppp2ca Regulation of Phosphorylation of Siglec1 1 0.06 0 0.08
86 INT196810 Binding of Prkaca and Ppp2ca 1 0.14 0 0.07
87 INT267014 Bdnf Negative_regulation of Gene_expression of Pdp1 1 0.07 0.08 0.07
88 INT113218 TNFRSF25 Positive_regulation of Localization of CYCS 1 0.18 0.74 0.07
89 INT218834 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.19 0.66 0.07
90 INT267005 Negative_regulation of Mdk Negative_regulation of Gene_expression of Pdp1 1 0.02 0.09 0.07
91 INT118260 Binding of TNF and CYCS 1 0.40 2.01 0.07
92 INT218829 Ppp1cc Regulation of Phosphorylation of Gria1 1 0.20 0.63 0.07
93 INT313463 Ppp2ca Regulation of Syp 1 0.43 0.6 0.06
94 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06
95 INT221815 PPARA Negative_regulation of PTEN 1 0.15 0.5 0.05
96 INT313462 Syp Positive_regulation of Binding of Ppp2ca 1 0.47 0 0.04
97 INT341237 ROS1 Negative_regulation of Ppp2r1a 1 0.01 0.31 0.04
98 INT259935 CSK Positive_regulation of Negative_regulation of LCK 1 0.09 0.57 0.03
99 INT313464 Negative_regulation of Ppp2ca Positive_regulation of Phosphorylation of Mapk1 1 0.09 0 0.03
100 INT256549 Binding of Pten and Mtor 1 0.00 1.02 0.03
101 INT248698 Mapk8 Positive_regulation of Ppm1e 1 0.00 0.31 0.03
102 INT313445 53T Regulation of Ppp2ca 1 0.00 0 0.03
103 INT259940 CSK Positive_regulation of Phosphorylation of LCK 1 0.09 0.51 0.03
104 INT329729 Binding of LCK and Fyn 1 0.00 0.21 0.03
105 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03
106 INT239466 Ppp2r1a Regulation of Phosphorylation of Akt1 1 0.01 0 0.03
107 INT244026 Ppp1cc Regulation of Phosphorylation of Camk2a 1 0.03 0 0
108 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
109 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
110 INT204997 Ppp1r15b Regulation of Mavs 1 0.00 0.87 0
111 INT250659 Negative_regulation of PTEN Positive_regulation of Positive_regulation of PIK3CB 1 0.02 1.18 0
112 INT276044 Binding of Pde1b and Ppp1cc 1 0.12 0 0
113 INT297212 Gene_expression of Ppp3ca Positive_regulation of Nfatc1 1 0.38 0.22 0
114 INT321718 Ins1 Regulation of Gene_expression of Pten 1 0.04 0.23 0
115 INT276073 Camk2a Regulation of Ppp1cc 1 0.10 0 0
116 INT313457 Ppp2ca Regulation of Th 1 0.36 0 0
117 INT163585 Lep Positive_regulation of Gene_expression of Epm2a 1 0.03 0.14 0
118 INT249825 Gopc Positive_regulation of Ppp4c 1 0.12 0.06 0
119 INT285908 AKT1 Regulation of Pten 1 0.01 0.53 0
120 INT196836 Binding of Ppp1cc and Phospho1 1 0.00 0 0
121 INT242674 Binding of Pde6b and Ppp3cb 1 0.00 0.6 0
122 INT313465 Syp Regulation of Regulation of Ppp2ca 1 0.26 0.56 0
123 INT348723 ED Positive_regulation of PTEN 1 0.04 1.3 0
124 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
125 INT313885 XRCC1 Positive_regulation of Localization of PTEN 1 0.00 0.65 0
126 INT293802 PTEN Regulation of PIK3CG 1 0.03 0.07 0
127 INT351682 Fut1 Positive_regulation of PTEN 1 0.01 1.81 0
128 INT204995 Ppp1r15b Regulation of Gene_expression of Pink1 1 0.01 0.97 0
129 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
130 INT223574 PTEN Negative_regulation of AKT1 1 0.06 0.56 0
131 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0
132 INT223579 PTEN Negative_regulation of PIK3CG 1 0.18 0.56 0
133 INT285910 Pten Regulation of AKT1 1 0.00 0.53 0
134 INT163584 Lep Positive_regulation of Epm2a 1 0.03 0.13 0
135 INT276074 Binding of Car2 and Ppp1cc 1 0.09 0 0
136 INT217770 MIR181A1 Regulation of PPP3CB 1 0.00 0.7 0
137 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0
138 INT244020 Ppp1cc Negative_regulation of Gabrg1 1 0.10 0 0
139 INT297215 Gene_expression of Ppp3ca Positive_regulation of Ppp3r1 1 0.36 0.22 0
140 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0
141 INT276068 Binding of Ppp1cc and Myoz1 1 0.02 0 0
142 INT313431 Positive_regulation of Binding of Ppp2ca and Gopc 1 0.11 0.34 0
143 INT275190 Localization of CD4 Positive_regulation of Positive_regulation of LCK 1 0.10 0.99 0
144 INT249824 Ppp4c Positive_regulation of Foxm1 1 0.24 0 0
145 INT313456 Binding of Ppp2ca and Gopc 1 0.08 0.68 0
146 INT87093 CYP3A Positive_regulation of Protein_catabolism of PPP4C 1 0.36 0 0
147 INT293804 PTEN Regulation of AKT1 1 0.04 0.07 0
148 INT276043 Binding of Calm3 and Ppp1cc 1 0.06 0 0
149 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein serine/threonine phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported in protein serine/threonine phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54
2 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57
3 INT90275 Negative_regulation of Ppp1cc 29 0.58 1.91 7.11
4 INT196782 Positive_regulation of Ppp2ca 32 0.61 1.89 4.33
5 INT90277 Negative_regulation of Ppp2ca 15 0.41 4.04 4.02
6 INT276198 Positive_regulation of Pten 1 0.52 5.02 3.88
7 INT151171 Positive_regulation of Pten 20 0.55 13.3 3.54
8 INT95119 Localization of CYCS 23 0.78 14.86 3.49
9 INT208291 Negative_regulation of Pten 2 0.44 5.42 3.36
10 INT196779 Phosphorylation of Ppp2ca 28 0.72 1.86 3.25
11 INT192676 Binding of PTEN 14 0.46 10.58 3.06
12 INT90276 Gene_expression of Ppp1cc 10 0.73 0.83 2.87
13 INT184477 Negative_regulation of Pten 27 0.59 15.61 2.8
14 INT161310 Negative_regulation of LCK 17 0.42 8.75 2.74
15 INT119383 Gene_expression of Pten 11 0.59 10.33 2.73
16 INT90273 Positive_regulation of Ppp1cc 10 0.41 0.82 2.71
17 INT98457 Phosphorylation of Ppp1cc 11 0.33 0.12 2.57
18 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5
19 INT91837 Negative_regulation of Ppp2r1a 4 0.48 0.95 2.41
20 INT100805 Binding of Ppp1cc 7 0.47 1.77 2.23
21 INT179885 Regulation of PTEN 8 0.26 11.88 2.18
22 INT122671 Positive_regulation of LCK 4 0.13 2.69 2.14
23 INT224615 Negative_regulation of Gene_expression of Pten 7 0.59 2.99 2.09
24 INT90272 Gene_expression of Ppp2ca 18 0.68 4.69 2.08
25 INT276201 Phosphorylation of Pten 1 0.61 1.31 2.08
26 INT15556 Positive_regulation of Epm2a 3 0.44 1.53 1.69
27 INT276171 Positive_regulation of Gene_expression of Pten 3 0.52 7.24 1.64
28 INT151169 Positive_regulation of Gene_expression of Pten 15 0.45 12.88 1.53
29 INT105086 Positive_regulation of CYCS 9 0.49 5.82 1.45
30 INT228249 Binding of Pten 7 0.48 3.26 1.45
31 INT122672 Regulation of Positive_regulation of LCK 1 0.06 1.15 1.44
32 INT281470 Regulation of Gene_expression of Pten 4 0.39 1.13 1.42
33 INT276196 Positive_regulation of Phosphorylation of Pten 1 0.38 0.19 1.41
34 INT304045 Transcription of PTEN 2 0.51 4.12 1.4
35 INT144805 Regulation of Negative_regulation of Ppp2ca 1 0.28 0.24 1.38
36 INT276181 Negative_regulation of Gene_expression of Pten 1 0.44 2.48 1.37
37 INT190014 Regulation of Pten 8 0.62 6.03 1.2
38 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19
39 INT111340 Positive_regulation of Localization of CYCS 7 0.67 4.83 1.19
40 INT196785 Regulation of Ppp2ca 5 0.54 2.1 1.17
41 INT53028 Negative_regulation of CYCS 6 0.57 2.65 1.11
42 INT248588 Gene_expression of LCK 9 0.28 4.9 0.98
43 INT90278 Localization of Ppp2ca 4 0.66 1.12 0.94
44 INT196754 Binding of Ppp2ca 5 0.37 0.42 0.89
45 INT276177 Regulation of Gene_expression of Pten 1 0.34 1.51 0.84
46 INT65886 Binding of PPP4C 3 0.40 0.08 0.83
47 INT161311 Positive_regulation of Negative_regulation of LCK 2 0.45 0.74 0.83
48 INT146942 Gene_expression of Lck 1 0.46 1.3 0.83
49 INT1523 Binding of CYCS 4 0.47 0.53 0.8
50 INT53287 Gene_expression of PPP4C 5 0.63 0 0.76
51 INT196741 Positive_regulation of Negative_regulation of Ppp1cc 3 0.33 0.42 0.76
52 INT119834 Phosphorylation of PTEN 12 0.79 6.78 0.75
53 INT162987 Positive_regulation of Ppm1e 1 0.03 0.06 0.74
54 INT122670 Negative_regulation of Positive_regulation of LCK 1 0.06 0.58 0.72
55 INT133484 Negative_regulation of Localization of CYCS 4 0.42 2.77 0.7
56 INT196753 Negative_regulation of Phosphorylation of Ppp2ca 3 0.37 0.52 0.7
57 INT169216 Negative_regulation of Positive_regulation of CYCS 1 0.42 0.82 0.7
58 INT196742 Positive_regulation of Positive_regulation of Ppp2ca 4 0.44 0.05 0.68
59 INT276199 Binding of Pten 2 0.30 0.4 0.67
60 INT53022 Gene_expression of CYCS 5 0.65 4.01 0.66
61 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63
62 INT196739 Regulation of Ppp1cc 5 0.19 0 0.63
63 INT329708 Transcription of LCK 1 0.04 1.54 0.63
64 INT276179 Regulation of Pten 1 0.46 0.81 0.63
65 INT296253 Negative_regulation of Gene_expression of Ppp2ca 3 0.41 1.71 0.62
66 INT196765 Positive_regulation of Gene_expression of Ppp2ca 4 0.44 1.05 0.6
67 INT100804 Regulation of Gene_expression of Ppp1cc 2 0.18 0 0.6
68 INT21087 Negative_regulation of Ppp3ca 2 0.32 0.31 0.58
69 INT161322 Localization of PTEN 9 0.73 5.65 0.57
70 INT100803 Regulation of Phosphorylation of Ppp1cc 1 0.10 0 0.57
71 INT162984 Phosphorylation of Ppm1e 1 0.05 0.09 0.52
72 INT243952 Phosphorylation of Ppp1ca 3 0.11 0.33 0.51
73 INT176146 Positive_regulation of Localization of PTEN 3 0.36 1.69 0.5
74 INT163579 Gene_expression of Epm2a 2 0.06 1.15 0.49
75 INT276174 Regulation of Negative_regulation of Pten 1 0.34 0.63 0.47
76 INT126428 Negative_regulation of Negative_regulation of Ppp1cc 1 0.42 0 0.45
77 INT26187 Regulation of CYCS 2 0.60 0.87 0.44
78 INT276180 Positive_regulation of Negative_regulation of Pten 1 0.35 0.89 0.43
79 INT276202 Negative_regulation of Protein_catabolism of Pten 1 0.32 0.78 0.42
80 INT167616 Protein_catabolism of Ppp2cb 1 0.02 0.87 0.42
81 INT276204 Protein_catabolism of Pten 1 0.75 0.77 0.41
82 INT203816 Localization of Pten 4 0.75 1.37 0.4
83 INT264827 Negative_regulation of Ppp1ca 2 0.08 0.19 0.4
84 INT312831 Negative_regulation of Lck 3 0.13 2.46 0.36
85 INT243978 Binding of Ppp2r1a 2 0.08 0 0.36
86 INT151167 Phosphorylation of Pten 3 0.72 1.69 0.35
87 INT151166 Positive_regulation of Phosphorylation of Pten 2 0.40 1.54 0.35
88 INT329707 Negative_regulation of Transcription of LCK 1 0.04 0.9 0.35
89 INT181413 Regulation of Lck 2 0.36 2.54 0.33
90 INT281469 Transcription of Pten 2 0.72 1.12 0.32
91 INT281474 Regulation of Transcription of Pten 1 0.62 0.35 0.32
92 INT263819 Regulation of Gene_expression of PTEN 1 0.25 0.63 0.32
93 INT196732 Localization of Ppp1cc 2 0.30 0 0.31
94 INT231658 Regulation of Epm2a 1 0.03 0.5 0.31
95 INT86549 Positive_regulation of Ppm1f 1 0.66 0 0.31
96 INT270927 Regulation of Binding of Ppp2r1a 1 0.04 0 0.29
97 INT270929 Regulation of Ppp2r1a 1 0.02 0 0.28
98 INT34275 Positive_regulation of Ppp3ca 2 0.31 0.24 0.27
99 INT264830 Regulation of Phosphorylation of Ppp1ca 1 0.05 0.06 0.27
100 INT133488 Negative_regulation of Phosphorylation of PTEN 4 0.41 1.88 0.26
101 INT43578 Negative_regulation of Pdp1 1 0.17 0 0.25
102 INT270161 Positive_regulation of Phosphorylation of Lck 1 0.13 0.23 0.23
103 INT196761 Regulation of Positive_regulation of Ppp2ca 2 0.40 0.05 0.22
104 INT278159 Regulation of LCK 1 0.04 0.98 0.22
105 INT1594 Binding of Ppp3ca 1 0.29 0 0.22
106 INT278161 Localization of LCK 1 0.27 0.98 0.22
107 INT196763 Positive_regulation of Regulation of Ppp2ca 1 0.30 0 0.21
108 INT196787 Positive_regulation of Localization of Ppp1cc 1 0.20 0 0.21
109 INT196759 Negative_regulation of Negative_regulation of Ppp2ca 2 0.30 0.17 0.2
110 INT192857 Gene_expression of Ppp2r1a 6 0.47 1.74 0.19
111 INT65887 Negative_regulation of Binding of PPP4C 1 0.20 0 0.18
112 INT65888 Negative_regulation of PPP4C 1 0.20 0 0.18
113 INT224616 Regulation of Negative_regulation of Pten 1 0.13 1.21 0.18
114 INT267027 Gene_expression of Pdp1 1 0.14 0.23 0.17
115 INT183242 Negative_regulation of Gene_expression of PTEN 6 0.55 3.81 0.16
116 INT196770 Negative_regulation of Positive_regulation of Ppp2ca 1 0.27 0 0.16
117 INT86546 Gene_expression of Ppm1f 1 0.64 0 0.14
118 INT130925 Protein_catabolism of CYCS 1 0.86 1.37 0.14
119 INT196751 Negative_regulation of Phosphorylation of Ppp1cc 1 0.17 0 0.14
120 INT1524 Positive_regulation of Binding of CYCS 1 0.67 0 0.14
121 INT337099 Positive_regulation of Phosphorylation of Ppp1ca 1 0.08 0.13 0.13
122 INT239373 Positive_regulation of Positive_regulation of PTEN 3 0.25 4.98 0.12
123 INT192856 Regulation of Gene_expression of Ppp2r1a 2 0.16 0.62 0.12
124 INT278162 Negative_regulation of Gene_expression of LCK 1 0.15 0.64 0.12
125 INT217824 Positive_regulation of PPP3CB 2 0.19 1.02 0.11
126 INT275204 Binding of LCK 2 0.12 1.19 0.11
127 INT270159 Positive_regulation of Lck 1 0.09 0.12 0.11
128 INT313409 Positive_regulation of Phosphorylation of Ppp2ca 1 0.39 0.16 0.11
129 INT87096 Negative_regulation of Protein_catabolism of PPP4C 1 0.22 0 0.11
130 INT270153 Phosphorylation of Lck 1 0.15 0.11 0.11
131 INT243967 Localization of Ppp1ca 1 0.01 0.15 0.11
132 INT87097 Protein_catabolism of PPP4C 1 0.58 0 0.11
133 INT313423 Positive_regulation of Localization of Ppp2ca 1 0.44 0.12 0.1
134 INT243986 Positive_regulation of Binding of Ppp2r1a 1 0.09 0 0.08
135 INT266511 Binding of Epm2a 1 0.11 0.17 0.08
136 INT243946 Negative_regulation of Binding of Ppp2r1a 1 0.07 0 0.08
137 INT239456 Phosphorylation of Ppp2r1a 2 0.16 1.01 0.07
138 INT53027 Positive_regulation of Negative_regulation of CYCS 1 0.45 0.07 0.07
139 INT259943 Phosphorylation of LCK 1 0.33 1.02 0.06
140 INT270639 Binding of Lck 2 0.30 1.21 0.05
141 INT236108 Positive_regulation of Positive_regulation of Pten 3 0.39 2.3 0.04
142 INT313406 Positive_regulation of Binding of Ppp2ca 1 0.44 0 0.04
143 INT176144 Positive_regulation of Phosphorylation of PTEN 1 0.36 0.29 0.04
144 INT233844 Negative_regulation of Positive_regulation of Pten 1 0.17 0.73 0.04
145 INT249796 Positive_regulation of Ppp4c 1 0.25 1.04 0.04
146 INT239453 Positive_regulation of Gene_expression of Ppp2r1a 1 0.03 0 0.03
147 INT313421 Regulation of Phosphorylation of Ppp2ca 1 0.40 0 0.03
148 INT239455 Positive_regulation of Ppp2r1a 1 0.03 0 0.03
149 INT248667 Gene_expression of Ppm1e 1 0.01 0.3 0.03
150 INT259944 Positive_regulation of Phosphorylation of LCK 1 0.18 0.56 0.03
151 INT249782 Gene_expression of Ppp4c 1 0.30 0.38 0.03
152 INT237440 Positive_regulation of Ppp3cb 2 0.02 1.61 0
153 INT315882 Regulation of Negative_regulation of PTEN 2 0.44 1.39 0
154 INT305346 Positive_regulation of Negative_regulation of Pten 2 0.41 0.91 0
155 INT249777 Localization of Ppp4c 1 0.33 0.22 0
156 INT242672 Gene_expression of Ppp3cb 1 0.01 0.63 0
157 INT167236 Regulation of Localization of CYCS 1 0.44 0 0
158 INT321706 Negative_regulation of Phosphorylation of Pten 1 0.38 0.16 0
159 INT313407 Regulation of Regulation of Ppp2ca 1 0.24 0.56 0
160 INT89797 Negative_regulation of Epm2a 1 0.37 0 0
161 INT297186 Negative_regulation of Gene_expression of Ppp3ca 1 0.30 0.24 0
162 INT53289 Regulation of Gene_expression of PPP4C 1 0.04 0 0
163 INT304062 Regulation of Localization of PTEN 1 0.43 1.29 0
164 INT351091 Negative_regulation of Binding of PTEN 1 0.09 0.23 0
165 INT249789 Negative_regulation of Localization of Ppp4c 1 0.19 0.22 0
166 INT249784 Positive_regulation of Gene_expression of Ppp4c 1 0.22 0.07 0
167 INT249771 Negative_regulation of Ppp4c 1 0.19 0.31 0
168 INT249781 Binding of Ppp4c 1 0.19 0.05 0
169 INT217815 Gene_expression of PPP3CB 1 0.01 1.07 0
170 INT334324 Positive_regulation of Negative_regulation of PTEN 1 0.41 0.81 0
171 INT287854 Negative_regulation of Ppp2cb 1 0.04 0 0
172 INT297195 Positive_regulation of Gene_expression of Ppp3ca 1 0.35 0.22 0
173 INT275997 Regulation of Negative_regulation of Ppp1cc 1 0.09 0 0
174 INT297194 Protein_catabolism of Ppp3ca 1 0.46 0.3 0
175 INT176158 Regulation of Positive_regulation of PTEN 1 0.32 0.23 0
176 INT297203 Gene_expression of Ppp3ca 1 0.55 0.74 0
177 INT204977 Positive_regulation of Ppp1r15b 1 0.01 0.49 0
178 INT348481 Positive_regulation of Positive_regulation of CYCS 1 0.18 0.32 0
179 INT275995 Positive_regulation of Positive_regulation of Ppp1cc 1 0.16 0 0
180 INT228244 Negative_regulation of Binding of Pten 1 0.16 0.72 0
181 INT275212 Positive_regulation of Gene_expression of LCK 1 0.14 0.97 0
182 INT217840 Regulation of PPP3CB 1 0.00 0.74 0
183 INT242673 Regulation of Ppp3cb 1 0.01 0.59 0
184 INT163583 Negative_regulation of Gene_expression of Epm2a 1 0.02 0.14 0
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