GO:0004741

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Name [pyruvate dehydrogenase (lipoamide)] phosphatase activity
Categary Function
Go Slim No
Go Link GO:0004741
Unique Molecular Interactions 13
Total Molecular Interactions 17
Total Single Events 78
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for [pyruvate dehydrogenase (lipoamide)] phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported for [pyruvate dehydrogenase (lipoamide)] phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
2 INT148380 PDP1 Positive_regulation of Positive_regulation of CP 1 0.12 0.64 0.44
3 INT267014 Bdnf Negative_regulation of Gene_expression of Pdp1 1 0.07 0.08 0.07
4 INT267005 Negative_regulation of Mdk Negative_regulation of Gene_expression of Pdp1 1 0.02 0.09 0.07
5 INT291105 FFAR1 Negative_regulation of PDP1 1 0.05 0.29 0
6 INT291100 PDP1 Regulation of FFAR1 1 0.03 0 0
7 INT291111 Positive_regulation of PYGM Regulation of PDP1 1 0.02 0 0
8 INT291101 Binding of PDHA1 and PDP1 1 0.22 0 0
9 INT291096 INS Positive_regulation of PDP1 1 0.21 0.06 0
10 INT291107 Regulation of PDP1 Regulation of FFAR1 1 0.03 0 0
11 INT291109 PYGM Regulation of PDP1 1 0.02 0 0
12 INT291099 FFAR1 Regulation of PDP1 1 0.05 0 0
13 INT291094 FFAR1 Positive_regulation of Phosphorylation of PDP1 1 0.05 0.24 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for [pyruvate dehydrogenase (lipoamide)] phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported in [pyruvate dehydrogenase (lipoamide)] phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68447 Positive_regulation of PDP1 11 0.64 5.69 0.83
2 INT5223 Negative_regulation of PDP1 8 0.41 1.74 0.37
3 INT291134 Gene_expression of PDP1 4 0.62 0.64 0.26
4 INT43578 Negative_regulation of Pdp1 1 0.17 0 0.25
5 INT68448 Negative_regulation of Positive_regulation of PDP1 4 0.40 1.84 0.24
6 INT267027 Gene_expression of Pdp1 1 0.14 0.23 0.17
7 INT291118 Transcription of PDP1 1 0.64 0 0.09
8 INT291143 Binding of PDP1 3 0.34 0.5 0.08
9 INT291120 Negative_regulation of Binding of PDP1 1 0.40 0 0.08
10 INT291152 Phosphorylation of PDP1 1 0.76 0.97 0.03
11 INT291155 Regulation of Phosphorylation of PDP1 1 0.42 0.16 0
12 INT291144 Positive_regulation of Regulation of PDP1 1 0.46 0.4 0
13 INT291148 Regulation of PDP1 1 0.57 1.08 0
14 INT291119 Positive_regulation of Positive_regulation of PDP1 1 0.46 0.33 0
15 INT291154 Negative_regulation of Gene_expression of PDP1 1 0.40 0 0
16 INT291142 Regulation of Binding of PDP1 1 0.42 0.16 0
17 INT291136 Positive_regulation of Phosphorylation of PDP1 1 0.46 0.36 0
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