GO:0004745

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Name retinol dehydrogenase activity
Categary Function
Go Slim No
Go Link GO:0004745
Unique Molecular Interactions 51
Total Molecular Interactions 81
Total Single Events 721
Pain Genes Associated 12

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for retinol dehydrogenase activity. They are ordered first by their pain relevance and then by number of times they were reported for retinol dehydrogenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01
2 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
3 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
4 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
5 INT59497 Adh1 Regulation of POMC 1 0.03 0 0.86
6 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
7 INT116926 Cpox Regulation of AKR1C3 1 0.01 0.28 0.45
8 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
9 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
10 INT330462 Ngf Positive_regulation of Gene_expression of Adh1 1 0.01 0.57 0.31
11 INT148342 Hsd17b6 Negative_regulation of Oxt 1 0.21 0.37 0.31
12 INT156087 Binding of AKR1C3 and Akr1c1 1 0.05 0.31 0.3
13 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
14 INT156083 Binding of AKR1C2 and AKR1C3 1 0.05 0.31 0.3
15 INT156084 Binding of PTGS2 and AKR1C3 1 0.02 0.31 0.3
16 INT156082 Binding of PTGS1 and AKR1C3 1 0.01 0.31 0.3
17 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
18 INT330463 Setd1a Positive_regulation of Regulation of Adh1 1 0.00 0.09 0.23
19 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
20 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
21 INT4262 IL8 Positive_regulation of Localization of Adh1 1 0.12 0 0.09
22 INT297968 Positive_regulation of Binding of BMP2 and IL17C 1 0.21 0.26 0.08
23 INT297970 Binding of BMP2 and IL17C 1 0.15 0.26 0.08
24 INT295122 Bmp2 Regulation of Grxcr1 1 0.02 0.66 0.06
25 INT295120 Bmp2 Regulation of Transcription of Pou1f1 1 0.24 0.66 0.06
26 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05
27 INT197741 Binding of Rdh5 and Positive_regulation of PPARA 1 0.27 0.95 0.05
28 INT170418 Ccrn4l Positive_regulation of Transcription of Adh4 1 0.11 0 0.05
29 INT335212 RDH5 Positive_regulation of NFAT5 1 0.00 0.96 0.04
30 INT335213 RDH5 Positive_regulation of CREM 1 0.00 0.96 0.04
31 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03
32 INT287233 PDLIM7 Positive_regulation of Gene_expression of BMP2 1 0.07 0.12 0.03
33 INT343999 INCENP Positive_regulation of BMP2 1 0.01 0 0
34 INT278021 BMP2 Positive_regulation of Gene_expression of RUNX1T1 1 0.02 0.5 0
35 INT335215 RDH5 Positive_regulation of Negative_regulation of ERBB3 1 0.03 0.98 0
36 INT205451 Binding of BMP2 and Acvr2a 1 0.02 0.05 0
37 INT302303 Binding of NR1H4 and Rdh5 1 0.02 0.11 0
38 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
39 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
40 INT342365 Binding of Rdh9 and OSBPL1A 1 0.40 0 0
41 INT344001 INCENP Positive_regulation of Gene_expression of BMP2 1 0.01 0 0
42 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
43 INT295129 Proc Regulation of Bmp2 1 0.00 0.48 0
44 INT342361 Binding of Irs1 and Rdh9 1 0.38 0 0
45 INT321594 Bmp2 Regulation of Gene_expression of Lxn 1 0.42 1.71 0
46 INT351002 Binding of Adh7 and Mrgpre 1 0.00 3.65 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for retinol dehydrogenase activity. They are ordered first by their pain relevance and then by number of times they were reported in retinol dehydrogenase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1261 Localization of Adh1 63 0.81 19.36 16.09
2 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65
3 INT4438 Negative_regulation of Localization of Adh1 18 0.59 6.23 6.95
4 INT21032 Gene_expression of Adh1 23 0.78 22.1 6.14
5 INT4598 Negative_regulation of Adh1 15 0.54 4.69 5.33
6 INT38087 Regulation of Adh1 15 0.61 4.56 4.83
7 INT108086 Negative_regulation of AKR1C3 17 0.58 7.7 3.99
8 INT4261 Positive_regulation of Localization of Adh1 11 0.61 2.04 3.49
9 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
10 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
11 INT33717 Regulation of Localization of Adh1 15 0.54 3.3 2.91
12 INT78146 Gene_expression of AKR1C3 24 0.77 5.71 2.77
13 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
14 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
15 INT47507 Negative_regulation of Gene_expression of Adh1 1 0.11 0.42 1.17
16 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
17 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
18 INT262366 Localization of Adh4 1 0.78 1.88 1
19 INT114664 Binding of BMP2 12 0.37 6.54 0.91
20 INT70818 Negative_regulation of Adh7 2 0.16 1.04 0.79
21 INT108085 Positive_regulation of Gene_expression of AKR1C3 2 0.53 0.58 0.75
22 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
23 INT116925 Binding of AKR1C3 2 0.36 0.75 0.56
24 INT85808 Localization of BMP2 7 0.77 1.94 0.51
25 INT145301 Regulation of Gene_expression of Bmp2 1 0.32 1.16 0.48
26 INT130391 Positive_regulation of AKR1C3 4 0.50 1.7 0.47
27 INT105408 Negative_regulation of Gene_expression of AKR1C3 1 0.23 0.56 0.45
28 INT120086 Gene_expression of Bmp2 5 0.27 2.34 0.43
29 INT21631 Positive_regulation of Gene_expression of Adh1 4 0.70 12.56 0.39
30 INT38575 Negative_regulation of Positive_regulation of Adh1 2 0.37 0.33 0.39
31 INT284683 Binding of Hsd17b6 1 0.03 0.64 0.38
32 INT84945 Transcription of BMP2 5 0.61 1.8 0.36
33 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35
34 INT38330 Binding of Adh1 4 0.41 3.98 0.3
35 INT38576 Transcription of Adh1 1 0.44 0.26 0.3
36 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24
37 INT109699 Regulation of BMP2 5 0.43 2.21 0.23
38 INT148064 Localization of Bmp2 2 0.29 0.14 0.17
39 INT106010 Positive_regulation of Bmp2 2 0.26 0.91 0.15
40 INT257276 Localization of RDH5 1 0.05 1.96 0.14
41 INT78144 Transcription of AKR1C3 4 0.72 1.21 0.13
42 INT284685 Positive_regulation of Binding of Hsd17b6 1 0.05 0.17 0.12
43 INT254992 Negative_regulation of Gene_expression of BMP2 3 0.34 0.56 0.11
44 INT238044 Positive_regulation of Transcription of BMP2 2 0.43 0.83 0.11
45 INT326976 Regulation of Localization of BMP2 1 0.59 0.08 0.1
46 INT196035 Localization of Bmp2 3 0.63 0.23 0.09
47 INT278036 Negative_regulation of BMP2 2 0.34 0.64 0.09
48 INT65839 Regulation of Regulation of Adh1 1 0.26 0.17 0.09
49 INT28904 Positive_regulation of Positive_regulation of Adh1 1 0.02 0.65 0.09
50 INT114663 Regulation of Binding of BMP2 1 0.38 0.19 0.09
51 INT43696 Negative_regulation of Regulation of Adh1 1 0.25 0.35 0.08
52 INT163072 Regulation of Binding of Bmp2 1 0.30 0.52 0.08
53 INT342321 Gene_expression of Rdh9 1 0.75 1.1 0.07
54 INT342334 Positive_regulation of Gene_expression of Rdh9 1 0.48 1.1 0.07
55 INT143828 Regulation of AKR1C3 1 0.06 1.32 0.07
56 INT197724 Binding of Rdh5 2 0.36 0.99 0.05
57 INT196025 Negative_regulation of Bmp2 2 0.34 0.14 0.05
58 INT170384 Positive_regulation of Transcription of Adh4 1 0.10 0 0.05
59 INT170379 Transcription of Adh4 1 0.15 0 0.05
60 INT350999 Gene_expression of Adh7 1 0.02 1.64 0.05
61 INT250290 Positive_regulation of Adh4 1 0.29 0.16 0.05
62 INT250292 Gene_expression of Adh4 1 0.34 0.17 0.05
63 INT229753 Positive_regulation of Gene_expression of Bmp2 2 0.11 1.22 0.04
64 INT287236 Positive_regulation of Positive_regulation of BMP2 1 0.29 0.08 0.04
65 INT351000 Binding of Adh7 1 0.01 3.4 0.03
66 INT189593 Regulation of Gene_expression of BMP2 2 0.33 0.8 0
67 INT145300 Positive_regulation of Positive_regulation of Bmp2 2 0.34 1.03 0
68 INT196031 Binding of Bmp2 1 0.16 0 0
69 INT278735 Negative_regulation of Gene_expression of Bmp2 1 0.43 0.06 0
70 INT342322 Regulation of Rdh9 1 0.26 0 0
71 INT342336 Binding of Rdh9 1 0.36 0.07 0
72 INT329048 Positive_regulation of Hsd17b6 1 0.03 0.41 0
73 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0
74 INT178540 Regulation of Gene_expression of AKR1C3 1 0.59 0.32 0
75 INT120087 Negative_regulation of Gene_expression of Bmp2 1 0.11 0.14 0
76 INT350998 Positive_regulation of Adh7 1 0.01 1.25 0
77 INT278040 Negative_regulation of Localization of BMP2 1 0.32 0.32 0
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