GO:0004843

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Name ubiquitin-specific protease activity
Categary Function
Go Slim No
Go Link GO:0004843
Unique Molecular Interactions 14
Total Molecular Interactions 15
Total Single Events 127
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ubiquitin-specific protease activity. They are ordered first by their pain relevance and then by number of times they were reported for ubiquitin-specific protease activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
2 INT306067 Binding of ADH5 and CYLD 1 0.02 3.13 0.19
3 INT313807 Binding of TYRP1 and YOD1 1 0.00 0.49 0.06
4 INT313804 Binding of VARS and YOD1 1 0.00 0.49 0.06
5 INT307223 CYLD Positive_regulation of Localization of BCL3 1 0.12 0.51 0.06
6 INT307226 CYLD Negative_regulation of Localization of BCL3 1 0.10 0.45 0.06
7 INT313806 Binding of TYR and YOD1 1 0.01 0.49 0.06
8 INT320439 Binding of Uchl5 and Psmb10 1 0.00 0 0.04
9 INT273519 NBN Negative_regulation of YOD1 1 0.03 0.56 0.03
10 INT307222 CYLD Regulation of Negative_regulation of BCL3 1 0.10 0.3 0
11 INT307225 CYLD Regulation of TNFRSF11A 1 0.14 0.81 0
12 INT313802 Binding of ASIP and YOD1 1 0.00 0.19 0
13 INT22675 Binding of USP6 and PNMA1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ubiquitin-specific protease activity. They are ordered first by their pain relevance and then by number of times they were reported in ubiquitin-specific protease activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136574 Regulation of TNFAIP3 2 0.11 1.33 1.3
2 INT156976 Gene_expression of TNFAIP3 4 0.65 5.25 0.93
3 INT181177 Gene_expression of CYLD 5 0.69 24.96 0.89
4 INT347182 Negative_regulation of TNFAIP3 3 0.23 5.6 0.84
5 INT264003 Positive_regulation of Transcription of TNFAIP3 1 0.38 1.01 0.65
6 INT263996 Transcription of TNFAIP3 1 0.39 0.99 0.64
7 INT181179 Binding of CYLD 4 0.43 7.06 0.39
8 INT185432 Negative_regulation of CYLD 4 0.52 3.19 0.35
9 INT185452 Regulation of CYLD 6 0.40 6.09 0.21
10 INT76177 Binding of YOD1 2 0.15 1.29 0.21
11 INT185753 Negative_regulation of YOD1 4 0.03 1.67 0.17
12 INT307231 Positive_regulation of Gene_expression of CYLD 1 0.45 2.37 0.14
13 INT185449 Regulation of Regulation of CYLD 1 0.21 2.03 0.13
14 INT307240 Localization of CYLD 3 0.72 3.09 0.1
15 INT185440 Negative_regulation of Negative_regulation of CYLD 1 0.20 1.02 0.08
16 INT185437 Negative_regulation of Gene_expression of CYLD 3 0.52 2.41 0.05
17 INT307229 Phosphorylation of CYLD 1 0.73 1.02 0.05
18 INT320365 Binding of Uchl5 1 0.02 0 0.04
19 INT176155 Gene_expression of USP6 7 0.65 1.84 0
20 INT217333 Positive_regulation of TNFAIP3 3 0.23 2.65 0
21 INT196297 Localization of USP6 2 0.73 0.33 0
22 INT300048 Binding of USP6 2 0.47 0.51 0
23 INT307235 Positive_regulation of Binding of CYLD 1 0.45 1.1 0
24 INT348456 Protein_catabolism of TNFAIP3 1 0.22 1.13 0
25 INT348453 Positive_regulation of Positive_regulation of TNFAIP3 1 0.17 1.06 0
26 INT307244 Regulation of Gene_expression of CYLD 1 0.24 1.84 0
27 INT327507 Negative_regulation of Localization of CYLD 1 0.05 0.58 0
28 INT307230 Regulation of Localization of CYLD 1 0.40 0.11 0
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