GO:0004859

From wiki-pain
Jump to: navigation, search
Name phospholipase inhibitor activity
Categary Function
Go Slim No
Go Link GO:0004859
Unique Molecular Interactions 41
Total Molecular Interactions 53
Total Single Events 319
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for phospholipase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported for phospholipase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT287746 Anxa1 Positive_regulation of Gene_expression of Lpar1 1 0.07 1.72 2.46
2 INT166842 Binding of ANXA1 and Nfkb1 1 0.37 1.64 0.95
3 INT166840 Binding of Anxa1 and Nfkb1 1 0.26 0.82 0.56
4 INT296237 Anxa1 Regulation of Gene_expression of Trpm8 1 0.03 0.57 0.43
5 INT296231 Anxa1 Regulation of Gene_expression of Trpa1 1 0.03 0.57 0.43
6 INT296235 Trpm8 Regulation of Positive_regulation of Anxa1 1 0.03 0.62 0.41
7 INT355984 PDC Positive_regulation of Gene_expression of IL17A 1 0.06 1.57 0.31
8 INT355979 Negative_regulation of PDC Positive_regulation of Gene_expression of IL17A 1 0.06 1.57 0.31
9 INT329173 Binding of PDC and RARRES2 1 0.07 1.02 0.3
10 INT287747 Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
11 INT287748 Positive_regulation of Anxa1 Positive_regulation of Lpar1 1 0.04 0 0.29
12 INT121249 Binding of ANXA5 and CASP3 1 0.36 0.67 0.25
13 INT121250 MEFV Positive_regulation of Binding of ANXA5 1 0.41 0.67 0.25
14 INT332481 ANXA1 Regulation of SGPP2 1 0.45 1.01 0.22
15 INT293056 Binding of ANXA5 and GOPC 1 0.06 0.51 0.19
16 INT296233 Binding of Anxa1 and Trpa1 1 0.03 0.78 0.14
17 INT332485 SGPP2 Regulation of ANXA1 1 0.27 0.69 0.13
18 INT311738 Binding of Anxa1 and Plat 1 0.19 0.63 0.1
19 INT242475 Ciapin1 Positive_regulation of Gene_expression of Anxa2 1 0.01 1.13 0.06
20 INT336992 Binding of PDC and DNAJC14 1 0.06 0 0.05
21 INT296236 Anxa1 Positive_regulation of Trpm8 1 0.04 0.09 0.05
22 INT332484 ANXA1 Positive_regulation of HSH2D 1 0.18 0.19 0.05
23 INT206845 ANXA1 Regulation of Gene_expression of ESR1 1 0.07 0.9 0.04
24 INT296232 Anxa1 Regulation of Trpm8 1 0.03 0.54 0.04
25 INT219195 Binding of PDC and fc 1 0.01 0.24 0.04
26 INT222532 Anxa1 Negative_regulation of Localization of Gh1 1 0.01 0.14 0.03
27 INT222538 Anxa1 Negative_regulation of Localization of Prl 1 0.04 0.14 0.03
28 INT222475 Anxa1 Negative_regulation of Localization of LH 1 0.01 0.14 0.03
29 INT352793 Binding of APOC1 and FGF21 1 0.01 2.76 0
30 INT180862 Binding of ANXA2 and S100A10 1 0.17 0.82 0
31 INT254745 Binding of Anxa3 and Skil 1 0.00 0 0
32 INT293055 Binding of ANXA5 and PRSS1 1 0.00 0.59 0
33 INT206844 ESR1 Positive_regulation of Gene_expression of ANXA1 1 0.08 0.1 0
34 INT332487 ANXA1 Regulation of Gene_expression of SGPP2 1 0.45 0.08 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for phospholipase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported in phospholipase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT62544 Gene_expression of Anxa1 21 0.47 13.56 9.71
2 INT80806 Gene_expression of PDC 12 0.75 4.34 5.73
3 INT80808 Positive_regulation of Gene_expression of PDC 5 0.53 3.13 3.96
4 INT85497 Gene_expression of Anxa1 6 0.77 4.7 3.68
5 INT46725 Localization of Anxa3 4 0.48 4.53 3.43
6 INT62547 Positive_regulation of Gene_expression of Anxa1 5 0.42 4.52 3.27
7 INT48042 Positive_regulation of Anxa1 5 0.50 3.64 3.19
8 INT134798 Gene_expression of ANXA1 15 0.75 13.94 2.99
9 INT96092 Binding of ANXA5 24 0.36 14.51 2.6
10 INT165726 Positive_regulation of Anxa1 7 0.29 3.16 2.57
11 INT132419 Positive_regulation of ANXA5 9 0.59 5.22 2.38
12 INT166838 Positive_regulation of ANXA1 4 0.64 4.88 2.16
13 INT70066 Positive_regulation of Localization of Anxa3 1 0.01 2.34 2.14
14 INT64676 Gene_expression of ANXA5 11 0.75 13.48 2.11
15 INT102843 Negative_regulation of PDC 5 0.57 4.26 1.82
16 INT85498 Positive_regulation of Gene_expression of Anxa1 3 0.50 2.12 1.7
17 INT85499 Regulation of Anxa1 1 0.27 1.88 1.52
18 INT133255 Gene_expression of Anxa2 8 0.41 8.52 1.3
19 INT71233 Negative_regulation of Anxa1 1 0.07 0.15 1.05
20 INT228871 Negative_regulation of Gene_expression of Anxa1 2 0.03 1.92 1.01
21 INT122151 Localization of Anxa1 1 0.75 0.53 1
22 INT132417 Transcription of ANXA5 2 0.59 1.82 0.95
23 INT80807 Positive_regulation of PDC 3 0.38 1.78 0.9
24 INT57954 Negative_regulation of Anxa3 4 0.11 4.51 0.89
25 INT295239 Negative_regulation of Anxa1 2 0.02 1.6 0.81
26 INT132418 Positive_regulation of Transcription of ANXA5 1 0.43 0.1 0.78
27 INT251820 Binding of PDC 4 0.28 2.37 0.68
28 INT80805 Regulation of PDC 1 0.34 0 0.67
29 INT166836 Negative_regulation of Positive_regulation of ANXA1 2 0.39 1.15 0.57
30 INT122149 Binding of Anxa1 1 0.36 0.22 0.57
31 INT37750 Localization of ANXA1 2 0.74 1.72 0.56
32 INT37749 Positive_regulation of Localization of ANXA1 1 0.01 0.67 0.53
33 INT206876 Positive_regulation of Gene_expression of ANXA1 3 0.39 1.68 0.51
34 INT166837 Binding of ANXA1 2 0.34 0.85 0.51
35 INT254731 Gene_expression of Anxa3 2 0.20 0.98 0.49
36 INT206858 Regulation of ANXA1 3 0.56 2.4 0.45
37 INT122150 Positive_regulation of Localization of Anxa1 1 0.47 0.28 0.44
38 INT166839 Negative_regulation of ANXA1 1 0.37 0.88 0.43
39 INT203309 Regulation of Anxa2 1 0.42 1.03 0.35
40 INT168569 Binding of Anxa3 1 0.36 0.53 0.34
41 INT355992 Negative_regulation of Negative_regulation of PDC 1 0.21 1.62 0.32
42 INT117968 Regulation of Anxa1 1 0.39 1.36 0.31
43 INT293061 Regulation of Binding of ANXA5 1 0.12 0.58 0.25
44 INT101226 Binding of Anxa2 3 0.05 0 0.2
45 INT83499 Phosphorylation of PDC 1 0.79 0 0.19
46 INT83498 Positive_regulation of Phosphorylation of PDC 1 0.49 0 0.19
47 INT293062 Negative_regulation of Binding of ANXA5 2 0.11 1.11 0.18
48 INT320010 Positive_regulation of Gene_expression of Anxa3 1 0.11 0.26 0.18
49 INT126804 Gene_expression of APOC1 1 0.75 1.06 0.14
50 INT112614 Positive_regulation of ANXA2 1 0.59 0.09 0.14
51 INT287734 Binding of Anxa1 1 0.03 0.18 0.14
52 INT296223 Regulation of Localization of Anxa1 1 0.03 0.35 0.11
53 INT296227 Localization of Anxa1 1 0.05 0.34 0.11
54 INT228594 Regulation of Gene_expression of ANXA5 1 0.04 0.36 0.11
55 INT268708 Phosphorylation of APOC1 1 0.38 1.02 0.09
56 INT290117 Negative_regulation of Gene_expression of ANXA1 1 0.57 1.15 0.08
57 INT32433 Regulation of Anxa3 2 0.04 1.21 0.07
58 INT133256 Transcription of Anxa2 1 0.04 1.5 0.07
59 INT206862 Regulation of Gene_expression of ANXA1 2 0.18 1.76 0.04
60 INT332510 Protein_catabolism of ANXA1 1 0.60 0.08 0.04
61 INT53928 Positive_regulation of Anxa3 1 0.00 0.07 0.04
62 INT199220 Negative_regulation of APOC1 1 0.02 1.89 0.03
63 INT296228 Positive_regulation of Positive_regulation of Anxa1 1 0.03 0.34 0.03
64 INT202685 Positive_regulation of Gene_expression of ANXA5 1 0.08 0.85 0
65 INT191180 Negative_regulation of ANXA5 1 0.04 0.62 0
66 INT301391 Protein_catabolism of Anxa1 1 0.01 1.03 0
67 INT330707 Localization of Anxa2 1 0.02 1.13 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox