GO:0004860

From wiki-pain
Jump to: navigation, search
Name protein kinase inhibitor activity
Categary Function
Go Slim No
Go Link GO:0004860
Unique Molecular Interactions 265
Total Molecular Interactions 333
Total Single Events 2118
Pain Genes Associated 17

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein kinase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported for protein kinase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT124547 Trib3 Regulation of Regulation of Th 1 0.02 0.79 2.64
2 INT112514 Binding of Prkaca and Trib3 1 0.03 1.18 1.9
3 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89
4 INT186433 Trib3 Regulation of Phosphorylation of Creb1 1 0.03 0.32 1.71
5 INT161191 CRX Regulation of Gene_expression of Trib3 1 0.00 2 1.38
6 INT50706 Phax Positive_regulation of Localization of Trib3 1 0.04 0.28 1.38
7 INT161185 NMS Regulation of Gene_expression of Trib3 1 0.03 2 1.38
8 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
9 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
10 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
11 INT202041 CAMK2N2 Negative_regulation of PPP1R11 1 0.00 0.74 1.25
12 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
13 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
14 INT202040 CAMK2N2 Negative_regulation of MMP7 1 0.00 0.73 1.24
15 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
16 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
17 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
18 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
19 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
20 INT348400 LPA Positive_regulation of Trib3 1 0.00 0.87 1.14
21 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
22 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
23 INT186431 Trib3 Regulation of Creb1 1 0.03 0.23 0.92
24 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
25 INT97735 Trib3 Positive_regulation of Mapk3 1 0.05 0.66 0.87
26 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
27 INT261480 Negative_regulation of Trib3 Positive_regulation of Ephb1 1 0.04 0.8 0.84
28 INT186428 Trib3 Regulation of Prkcg 1 0.02 0.09 0.81
29 INT128041 Bdnf Positive_regulation of Trib3 1 0.10 0.29 0.79
30 INT50708 Phax Positive_regulation of Trib3 1 0.03 0.07 0.77
31 INT50707 Phax Positive_regulation of Positive_regulation of Trib3 1 0.04 0.16 0.74
32 INT161298 Ppp1r1b Negative_regulation of Trib3 1 0.05 0.16 0.7
33 INT82022 Binding of Trib3 and Ngf 1 0.08 0.31 0.68
34 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
35 INT82020 Negative_regulation of Binding of Trib3 and Ngf 1 0.07 0.31 0.68
36 INT134028 Olr696 Regulation of Trib3 1 0.00 0.15 0.68
37 INT112515 Binding of Ephb1 and Trib3 1 0.06 0.41 0.65
38 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
39 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
40 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
41 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
42 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
43 INT166395 CDKN1A Regulation of Gene_expression of IFI27 1 0.32 0.83 0.61
44 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
45 INT166392 IFI27 Regulation of Gene_expression of CDKN1A 1 0.32 0.83 0.61
46 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
47 INT186434 Trib3 Positive_regulation of Phosphorylation of Creb1 1 0.05 0.26 0.58
48 INT118003 Trib3 Regulation of Trpv1 1 0.03 0.09 0.58
49 INT282142 Grm1 Positive_regulation of Positive_regulation of Trib3 1 0.01 0.27 0.57
50 INT162994 Binding of Akt1 and Trib3 1 0.04 0.09 0.54
51 INT161250 Trib3 Regulation of Mapk14 1 0.04 0.81 0.54
52 INT149321 Amph Positive_regulation of Trib3 1 0.16 0 0.54
53 INT330545 Bcl2l11 Negative_regulation of Trib3 1 0.00 0.38 0.52
54 INT162993 Binding of Trib3 and Fadd 1 0.05 0.1 0.46
55 INT162990 Binding of Trib3 and Pea15a 1 0.04 0.09 0.46
56 INT128043 Positive_regulation of Ntrk2 Positive_regulation of Phosphorylation of Trib3 1 0.07 0.34 0.45
57 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
58 INT283731 Trib3 Positive_regulation of Creb1 2 0.01 0.16 0.44
59 INT313377 Trib3 Regulation of Gene_expression of Gfap 1 0.01 0.37 0.44
60 INT313378 Trib3 Regulation of Phosphorylation of Mapk14 1 0.01 0.37 0.44
61 INT114599 Positive_regulation of Il1rap Positive_regulation of Trib3 1 0.03 0.07 0.43
62 INT95403 Ephb1 Regulation of Positive_regulation of Trib3 1 0.07 0.19 0.41
63 INT95402 Mapk14 Regulation of Positive_regulation of Trib3 1 0.06 0.19 0.41
64 INT114598 Positive_regulation of Il1b Positive_regulation of Trib3 1 0.08 0.08 0.4
65 INT114594 Il1b Positive_regulation of Positive_regulation of Trib3 1 0.08 0.08 0.4
66 INT114596 Il1b Positive_regulation of Trib3 1 0.08 0.08 0.4
67 INT114597 Positive_regulation of Trib3 Regulation of Gene_expression of Tac4 1 0.01 0.09 0.4
68 INT140869 Binding of Gdnf and Trib3 1 0.04 0.15 0.37
69 INT118000 Trpv1 Regulation of Phosphorylation of Trib3 1 0.01 0.08 0.36
70 INT117999 Trpv1 Positive_regulation of Phosphorylation of Trib3 1 0.02 0.08 0.36
71 INT224285 BDNF Positive_regulation of Trib3 1 0.06 0.22 0.36
72 INT122757 Helt Positive_regulation of Trib3 1 0.00 0.2 0.35
73 INT263383 Abl1 Regulation of Trib3 1 0.01 0.28 0.35
74 INT249492 Trib3 Regulation of Phosphorylation of Grin2b 1 0.01 0.23 0.35
75 INT304495 Trib3 Positive_regulation of Mapk1 1 0.02 1.4 0.35
76 INT263382 Src Regulation of Trib3 1 0.00 0.29 0.35
77 INT78368 IGKV2D-29 Positive_regulation of PKIB 1 0.07 0.26 0.35
78 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34
79 INT119262 PPM1E Negative_regulation of Positive_regulation of CDKN1A 1 0.01 0.96 0.33
80 INT309132 Edc4 Negative_regulation of Positive_regulation of Trib3 1 0.00 0.69 0.33
81 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
82 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
83 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
84 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
85 INT356288 Egf Positive_regulation of Trib3 1 0.00 0.17 0.3
86 INT186430 Creb1 Positive_regulation of Trib3 1 0.04 0.17 0.3
87 INT356283 Ngf Positive_regulation of Trib3 1 0.00 0.17 0.3
88 INT356282 Gdnf Positive_regulation of Trib3 1 0.00 0.17 0.3
89 INT283733 Trib3 Positive_regulation of Creb1 1 0.00 0 0.28
90 INT172977 Cdkn1a Negative_regulation of Positive_regulation of Inca1 1 0.00 1.39 0.27
91 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
92 INT53951 Negative_regulation of Trib3 Negative_regulation of Gene_expression of Ptgs1 1 0.01 0.43 0.26
93 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
94 INT149357 Trib3 Negative_regulation of Raf1 1 0.01 0.08 0.25
95 INT51432 Gria1 Positive_regulation of Trib3 1 0.04 0 0.25
96 INT177661 Binding of Trib3 and Myo1f 1 0.00 0.54 0.24
97 INT210785 Cdkn1c Positive_regulation of Itgbl1 1 0.38 0 0.23
98 INT245555 Runx1 Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
99 INT245565 Runx1 Negative_regulation of Negative_regulation of Cdkn1a 1 0.29 1.17 0.23
100 INT157211 Binding of AGXT and WNK1 1 0.07 0.68 0.22
101 INT157212 Binding of SPTLC1 and WNK1 1 0.07 0.67 0.22
102 INT157216 Binding of SPTLC2 and WNK1 1 0.03 0.68 0.22
103 INT187485 Trib3 Positive_regulation of Prkag1 1 0.00 0.97 0.22
104 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2
105 INT179937 Trib3 Regulation of TNF 1 0.00 0.59 0.2
106 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
107 INT212084 NOXO1 Positive_regulation of CDKN1A 1 0.06 0.53 0.19
108 INT345209 Repin1 Positive_regulation of Positive_regulation of Trib3 1 0.00 0.88 0.18
109 INT140870 Binding of Trib3 and Gtf3a 1 0.00 0.07 0.18
110 INT164790 Cdk5r1 Positive_regulation of Trib3 1 0.02 0.25 0.17
111 INT119263 Binding of CDKN1A and PPM1E 1 0.01 0.46 0.17
112 INT146841 Tnf Positive_regulation of Trib3 1 0.03 0.77 0.16
113 INT309125 Trib3 Positive_regulation of Rorb 1 0.00 0.16 0.16
114 INT146845 Tnf Positive_regulation of Positive_regulation of Trib3 1 0.03 0.77 0.16
115 INT226367 INCENP Negative_regulation of SOCS1 1 0.01 0.47 0.15
116 INT153185 Prok2 Regulation of Trib3 1 0.02 0 0.15
117 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
118 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
119 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14
120 INT193789 SDF2L1 Positive_regulation of CDKN1A 1 0.00 0.68 0.13
121 INT226378 INCENP Positive_regulation of Transcription of SOCS1 1 0.01 0.41 0.13
122 INT352450 Tnc Regulation of Trib3 1 0.00 0.22 0.13
123 INT193785 SDF2L1 Positive_regulation of Gene_expression of CDKN1A 1 0.00 0.68 0.13
124 INT133349 Positive_regulation of Trib3 Positive_regulation of Gene_expression of Qrfp 1 0.02 0 0.12
125 INT153620 Binding of Ntrk1 and WNK1 1 0.02 0.85 0.12
126 INT177675 Binding of CALM1 and Positive_regulation of Trib3 1 0.00 0.27 0.12
127 INT177674 CALM1 Positive_regulation of Trib3 1 0.00 0.27 0.12
128 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12
129 INT285981 Ros1 Regulation of Positive_regulation of Trib3 1 0.01 0.95 0.12
130 INT278156 Negative_regulation of Trib3 Negative_regulation of Akt1 1 0.00 0.45 0.1
131 INT15902 PKIA Negative_regulation of Positive_regulation of Prkaca 1 0.10 0 0.1
132 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
133 INT321299 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Nr0b2 1 0.02 0.31 0.1
134 INT179871 IK Positive_regulation of SOCS3 1 0.01 1 0.1
135 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
136 INT335772 MIR155 Regulation of SOCS1 1 0.01 0.29 0.09
137 INT237922 TNFSF10 Positive_regulation of CDKN1A 1 0.09 3.28 0.08
138 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
139 INT273373 SOCS3 Regulation of Phosphorylation of STAT3 1 0.42 0.06 0.08
140 INT248704 Trib3 Positive_regulation of Phosphorylation of Rxrb 1 0.00 0.49 0.08
141 INT285982 Ros1 Positive_regulation of Binding of Trib3 1 0.02 1.41 0.08
142 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
143 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08
144 INT110855 Pkia Negative_regulation of Egf 1 0.15 1.2 0.08
145 INT220514 Ppara Positive_regulation of Gene_expression of Cdkn1b 1 0.08 1 0.08
146 INT285602 Trib3 Regulation of Gene_expression of Nos2 1 0.00 0.48 0.07
147 INT273369 SOCS3 Negative_regulation of JAK1 1 0.03 0 0.07
148 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
149 INT263430 Binding of Wasf1 and Trib3 1 0.01 0.06 0.07
150 INT193783 ITIH4 Regulation of Gene_expression of CDKN1A 1 0.03 0.55 0.07
151 INT273363 SOCS3 Regulation of Protein_catabolism of SOCS1 1 0.02 0 0.07
152 INT119268 CDKN1A Regulation of CREBBP 1 0.21 0.44 0.07
153 INT215693 Trib3 Regulation of Gene_expression of Ccnd1 1 0.00 0.09 0.07
154 INT273364 SOCS3 Regulation of SOCS1 1 0.02 0 0.07
155 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
156 INT300308 Positive_regulation of Mapk14 Positive_regulation of Trib3 1 0.03 1.42 0.07
157 INT273371 JAK2 Regulation of Protein_catabolism of SOCS1 1 0.01 0 0.06
158 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06
159 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06
160 INT292812 Zfp787 Negative_regulation of Trib3 1 0.00 0.48 0.06
161 INT273365 JAK2 Regulation of SOCS1 1 0.01 0 0.06
162 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
163 INT213001 Hdl1 Positive_regulation of Trib3 1 0.00 2 0.06
164 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06
165 INT179932 Trib3 Negative_regulation of Positive_regulation of Mmp9 1 0.01 0.41 0.05
166 INT308328 Hif1a Regulation of Positive_regulation of Trib3 1 0.02 0.89 0.05
167 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05
168 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
169 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05
170 INT179933 Trib3 Negative_regulation of Gene_expression of Mmp9 1 0.01 0.41 0.05
171 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05
172 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05
173 INT270659 Wnk1 Regulation of Napg 1 0.04 1.12 0.04
174 INT295263 Tlr4 Positive_regulation of Trib3 1 0.18 0.66 0.04
175 INT148095 Vasp Regulation of Trib3 1 0.00 0.12 0.04
176 INT284097 Binding of MAP4 and WNK1 1 0.39 0.82 0.04
177 INT270661 Regulation of Wnk1 Regulation of Napg 1 0.04 1.13 0.04
178 INT263378 Trib3 Regulation of Bmx 1 0.00 0 0.04
179 INT263431 Trib3 Regulation of Pdgfra 1 0.00 0 0.04
180 INT263381 Trib3 Regulation of Src 1 0.01 0 0.04
181 INT263432 Trib3 Regulation of Abl1 1 0.00 0 0.04
182 INT176224 Binding of CDKN1A and PCNA 4 0.08 2.52 0.03
183 INT213002 Binding of Scarb1 and Trib3 1 0.00 1.02 0.03
184 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03
185 INT53100 Trib3 Regulation of Gene_expression of Penk 1 0.06 0 0.03
186 INT303091 Rorb Regulation of CDKN1A 1 0.00 0.52 0.03
187 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
188 INT283722 Id2 Negative_regulation of Transcription of CDKN1A 1 0.45 0.11 0.03
189 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
190 INT277745 Trib3 Regulation of Ccnd1 1 0.00 0.41 0.03
191 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
192 INT277223 Trib3 Regulation of Regulation of aicda 1 0.01 0.42 0.03
193 INT223066 CDKN1A Negative_regulation of CCND1 1 0.04 0.66 0.03
194 INT201771 CDKN1A Positive_regulation of Localization of Ccnd1 1 0.04 0 0
195 INT325154 CDKN1B Negative_regulation of CCNE2 1 0.07 0.1 0
196 INT233276 Cdkn1a Regulation of Hoxa10 1 0.12 0.26 0
197 INT182942 VDR Positive_regulation of CDKN1A 1 0.35 0.38 0
198 INT295045 Akt1 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.09 2.06 0
199 INT355435 Trib3 Positive_regulation of Eif2ak2 1 0.01 0.61 0
200 INT205985 Ptn Positive_regulation of Trib3 1 0.00 0.73 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein kinase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported in protein kinase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01
2 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48
3 INT12681 Regulation of Trib3 76 0.53 23.92 26.58
4 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27
5 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58
6 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3
7 INT38253 Localization of Trib3 35 0.63 10.28 15.42
8 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74
9 INT33127 Positive_regulation of Phosphorylation of Trib3 26 0.17 14.04 10
10 INT62269 Gene_expression of Cdkn1a 60 0.73 35.78 9.84
11 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69
12 INT10533 Positive_regulation of Positive_regulation of Trib3 24 0.42 6.59 9.2
13 INT38254 Positive_regulation of Localization of Trib3 14 0.45 6.14 6.99
14 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88
15 INT62270 Positive_regulation of Gene_expression of Cdkn1a 30 0.47 18.73 5.69
16 INT50704 Binding of Trib3 13 0.31 6.33 5.46
17 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
18 INT51734 Negative_regulation of Localization of Trib3 10 0.19 2.53 4.97
19 INT26058 Gene_expression of SH3BP5 12 0.23 2.81 4.88
20 INT160055 Localization of CDKN1A 15 0.78 12.56 4.83
21 INT24813 Negative_regulation of Positive_regulation of Trib3 10 0.16 1.3 4.48
22 INT32205 Regulation of Positive_regulation of Trib3 9 0.11 2.82 4.1
23 INT10535 Positive_regulation of Gene_expression of Trib3 13 0.59 4.93 3.74
24 INT82796 Regulation of CDKN1A 22 0.53 9.83 3.33
25 INT62268 Positive_regulation of Cdkn1a 33 0.67 14.12 3.26
26 INT48437 Positive_regulation of SH3BP5 4 0.20 2.41 3.09
27 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07
28 INT15327 Negative_regulation of Phosphorylation of Trib3 7 0.30 4.95 2.99
29 INT75499 Positive_regulation of Positive_regulation of CDKN1A 12 0.60 7.28 2.84
30 INT86592 Positive_regulation of PKIB 3 0.09 0.54 2.75
31 INT33492 Negative_regulation of Negative_regulation of Trib3 5 0.30 0.51 2.67
32 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
33 INT249563 Positive_regulation of Trib3 1 0.45 0.94 2.18
34 INT249555 Localization of Trib3 1 0.73 0.94 2.18
35 INT26415 Regulation of Phosphorylation of PKIA 1 0.01 0.06 2.04
36 INT26417 Phosphorylation of PKIA 1 0.02 0.06 2.04
37 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
38 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
39 INT32469 Regulation of Gene_expression of Trib3 5 0.07 2.33 1.7
40 INT48752 Regulation of Negative_regulation of Trib3 3 0.39 0.89 1.65
41 INT104331 Negative_regulation of Gene_expression of CDKN1A 24 0.57 13.68 1.63
42 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
43 INT86591 Positive_regulation of Positive_regulation of PKIB 2 0.09 0.48 1.43
44 INT99639 Regulation of Phosphorylation of Trib3 6 0.14 0.44 1.36
45 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
46 INT202054 Negative_regulation of CAMK2N2 1 0.01 0.88 1.29
47 INT56805 Localization of SH3BP5 2 0.70 0.42 1.25
48 INT26061 Positive_regulation of Gene_expression of SH3BP5 2 0.13 1.28 1.25
49 INT93625 Gene_expression of Cdkn1c 2 0.75 0.42 1.2
50 INT83061 Regulation of Localization of Trib3 2 0.07 0.11 1.17
51 INT179884 Gene_expression of SOCS3 10 0.67 16.57 1.14
52 INT77246 Positive_regulation of WNK1 5 0.10 4.24 1.13
53 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
54 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
55 INT26063 Regulation of SH3BP5 2 0.45 1.99 0.92
56 INT48931 Regulation of Regulation of Trib3 2 0.04 0.06 0.89
57 INT220498 Negative_regulation of Gene_expression of Cdkn1b 9 0.21 7.48 0.8
58 INT146521 Negative_regulation of Positive_regulation of CDKN1A 6 0.42 3.29 0.79
59 INT93621 Positive_regulation of Gene_expression of Cdkn1c 1 0.67 0.42 0.77
60 INT77247 Binding of WNK1 5 0.46 3.45 0.7
61 INT126732 Regulation of Cdkn1a 6 0.39 2.13 0.63
62 INT98786 Positive_regulation of Gene_expression of Cdkn1b 21 0.67 8.7 0.56
63 INT36619 Gene_expression of SOCS1 9 0.44 4.83 0.55
64 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55
65 INT56806 Negative_regulation of Localization of SH3BP5 1 0.37 0.2 0.5
66 INT129635 Positive_regulation of SOCS1 3 0.49 0.92 0.49
67 INT163828 Localization of Cdkn1b 4 0.66 5.2 0.48
68 INT179887 Positive_regulation of SOCS3 10 0.50 13.06 0.45
69 INT137504 Positive_regulation of Positive_regulation of Cdkn1b 2 0.45 1.71 0.45
70 INT129636 Transcription of SOCS1 2 0.52 1.29 0.45
71 INT163829 Positive_regulation of Localization of Cdkn1b 2 0.17 0.96 0.45
72 INT97606 Negative_regulation of Cdkn1a 7 0.43 4.24 0.42
73 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41
74 INT131018 Phosphorylation of Cdkn1a 3 0.61 2.06 0.4
75 INT285500 Binding of Cdkn1c 1 0.18 0.76 0.34
76 INT129153 Phosphorylation of CDKN1B 2 0.61 1.41 0.33
77 INT82797 Transcription of CDKN1A 11 0.69 8.01 0.32
78 INT131017 Positive_regulation of Positive_regulation of Cdkn1a 5 0.67 1.89 0.32
79 INT119269 Binding of CDKN1A 14 0.47 8.82 0.31
80 INT110852 Binding of Pkia 1 0.12 1.04 0.3
81 INT123529 Phosphorylation of CDKN1A 8 0.80 5.69 0.29
82 INT157219 Gene_expression of WNK1 4 0.58 2.5 0.28
83 INT15899 Gene_expression of PKIA 1 0.61 0 0.28
84 INT203616 Positive_regulation of CDKN1C 2 0.60 12.62 0.27
85 INT164728 Positive_regulation of Cdkn1c 1 0.36 0.3 0.26
86 INT225177 Regulation of Negative_regulation of CDKN1A 1 0.39 0.26 0.25
87 INT248401 Gene_expression of CDKN1C 21 0.67 14.52 0.23
88 INT179043 Negative_regulation of Cdkn1b 7 0.36 5.99 0.22
89 INT233869 Binding of CDKN1B 2 0.47 0.46 0.22
90 INT226426 Negative_regulation of SOCS3 2 0.15 10.24 0.22
91 INT179889 Negative_regulation of CDKN1B 4 0.57 1.71 0.21
92 INT306296 Regulation of CDKN1B 1 0.19 0.46 0.21
93 INT310369 Protein_catabolism of Trib3 2 0.01 0.43 0.2
94 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18
95 INT188059 Transcription of Trib3 3 0.05 1.07 0.18
96 INT14904 Gene_expression of CAMK2N2 1 0.00 0.56 0.18
97 INT248400 Regulation of CDKN1C 1 0.45 2.92 0.17
98 INT67625 Positive_regulation of Regulation of Trib3 1 0.10 0.24 0.17
99 INT201689 Protein_catabolism of CDKN1B 3 0.96 0.7 0.16
100 INT335807 Localization of SOCS1 1 0.36 0.41 0.15
101 INT245263 Negative_regulation of Gene_expression of Cdkn1a 5 0.25 1.84 0.14
102 INT223048 Binding of SH3BP5 1 0.00 0.06 0.14
103 INT248403 Positive_regulation of Gene_expression of CDKN1C 1 0.40 7.77 0.14
104 INT123181 Positive_regulation of Negative_regulation of CDKN1A 1 0.49 0.6 0.14
105 INT289345 Positive_regulation of Negative_regulation of Trib3 2 0.03 0.54 0.13
106 INT226477 Positive_regulation of Transcription of SOCS1 1 0.21 0.41 0.13
107 INT179034 Binding of Cdkn1b 7 0.31 5.12 0.12
108 INT24239 Positive_regulation of Pkia 1 0.18 0.31 0.12
109 INT24243 Phosphorylation of Pkia 1 0.22 0.33 0.12
110 INT188062 Regulation of Transcription of Trib3 1 0.02 0.25 0.12
111 INT273407 Transcription of SOCS3 1 0.62 0.17 0.11
112 INT179890 Localization of SOCS3 1 0.54 1.02 0.1
113 INT220494 Negative_regulation of Positive_regulation of Cdkn1b 1 0.14 0.35 0.1
114 INT233868 Localization of CDKN1B 2 0.73 0.37 0.09
115 INT26062 Positive_regulation of Regulation of SH3BP5 1 0.04 0.75 0.09
116 INT268281 Negative_regulation of SOCS1 3 0.21 1.12 0.08
117 INT343445 Binding of SOCS1 1 0.02 0.07 0.08
118 INT210778 Negative_regulation of Cdkn1c 1 0.36 0 0.08
119 INT352530 Positive_regulation of Positive_regulation of SOCS3 1 0.15 1.77 0.08
120 INT273403 Positive_regulation of Transcription of SOCS3 1 0.40 0.06 0.08
121 INT233871 Negative_regulation of Protein_catabolism of CDKN1B 1 0.57 0.27 0.08
122 INT110853 Negative_regulation of Pkia 1 0.14 1.19 0.08
123 INT245267 Negative_regulation of Trib3 1 0.21 0.64 0.08
124 INT273397 Binding of SOCS3 1 0.42 0 0.07
125 INT69139 Gene_expression of Trib3 1 0.01 0.68 0.07
126 INT328542 Regulation of Positive_regulation of Cdkn1a 1 0.03 0.79 0.07
127 INT273405 Negative_regulation of Binding of SOCS3 1 0.37 0 0.07
128 INT176262 Positive_regulation of Phosphorylation of CDKN1A 3 0.49 2.12 0.06
129 INT273400 Protein_catabolism of SOCS1 1 0.05 0 0.06
130 INT234134 Positive_regulation of Transcription of Trib3 1 0.03 0.12 0.06
131 INT179033 Negative_regulation of Regulation of Cdkn1b 1 0.36 1.34 0.05
132 INT300107 Positive_regulation of Gene_expression of SOCS3 1 0.15 3.58 0.05
133 INT220489 Regulation of Gene_expression of Cdkn1b 1 0.20 1.57 0.04
134 INT316430 Positive_regulation of Negative_regulation of Cdkn1a 1 0.19 1.24 0.04
135 INT224295 Protein_catabolism of CDKN1A 1 0.12 0.55 0.03
136 INT300092 Regulation of SOCS3 1 0.08 3.03 0.03
137 INT203619 Positive_regulation of Positive_regulation of CDKN1C 1 0.13 0.34 0.03
138 INT123524 Phosphorylation of Cdkn1b 4 0.29 2.29 0
139 INT172965 Negative_regulation of Positive_regulation of Cdkn1a 4 0.41 1.84 0
140 INT248399 Negative_regulation of CDKN1C 2 0.37 2.71 0
141 INT271100 Regulation of Positive_regulation of CDKN1A 2 0.44 1.52 0
142 INT276307 Protein_catabolism of Cdkn1b 2 0.45 2.57 0
143 INT233247 Transcription of Cdkn1a 1 0.39 0.26 0
144 INT277672 Localization of Cdkn1a 1 0.07 0.95 0
145 INT295040 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.21 1 0
146 INT179648 Localization of WNK1 1 0.38 0.92 0
147 INT309294 Negative_regulation of Gene_expression of WNK1 1 0.04 0 0
148 INT325178 Regulation of Positive_regulation of CDKN1B 1 0.44 0.05 0
149 INT325180 Negative_regulation of Gene_expression of CDKN1B 1 0.57 0.25 0
150 INT77738 Transcription of SH3BP5 1 0.03 0.1 0
151 INT322505 Transcription of Cdkn1b 1 0.26 1.02 0
152 INT234133 Negative_regulation of Gene_expression of Trib3 1 0.03 0.13 0
153 INT266668 Negative_regulation of SH3BP5 1 0.06 0.06 0
154 INT322508 Regulation of Localization of Cdkn1b 1 0.10 0.4 0
155 INT345669 Regulation of Gene_expression of WNK1 1 0.01 0.15 0
156 INT282083 Regulation of Gene_expression of Cdkn1a 1 0.15 1.25 0
157 INT322519 Negative_regulation of Transcription of Cdkn1b 1 0.16 0.07 0
158 INT322517 Positive_regulation of Transcription of Cdkn1b 1 0.17 0.64 0
159 INT234750 Regulation of Regulation of CDKN1A 1 0.09 0.45 0
160 INT248402 Negative_regulation of Positive_regulation of CDKN1C 1 0.37 1.04 0
161 INT276316 Positive_regulation of Negative_regulation of Cdkn1b 1 0.07 0.56 0
162 INT225184 Positive_regulation of Binding of CDKN1A 1 0.43 0.87 0
163 INT300103 Positive_regulation of Negative_regulation of SOCS3 1 0.15 1.75 0
164 INT322506 Negative_regulation of Phosphorylation of Cdkn1b 1 0.16 0.07 0
165 INT277673 Positive_regulation of Localization of Cdkn1a 1 0.05 1.01 0
166 INT282089 Binding of Cdkn1a 1 0.12 0.36 0
167 INT250716 Positive_regulation of Transcription of CDKN1A 1 0.18 0.48 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox