GO:0004865

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Name protein serine/threonine phosphatase inhibitor activity
Categary Function
Go Slim No
Go Link GO:0004865
Unique Molecular Interactions 22
Total Molecular Interactions 32
Total Single Events 200
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for protein serine/threonine phosphatase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported for protein serine/threonine phosphatase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100816 PPP1R14C Regulation of Ppp1cc 1 0.08 0 1.27
2 INT196812 Ppp1r1b Negative_regulation of Ppp1cc 3 0.07 0.13 1.12
3 INT196834 Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 2 0.15 0 0.87
4 INT112914 Ppp1r1b Negative_regulation of Prkaca 3 0.22 0.13 0.86
5 INT112916 Nts Regulation of Phosphorylation of Ppp1r1b 1 0.47 0 0.55
6 INT196824 Ppp1r1b Regulation of Prkaca 1 0.10 0 0.51
7 INT196826 Ppp1r1b Regulation of Ppp1cc 1 0.10 0 0.51
8 INT228850 Dio1 Positive_regulation of Phosphorylation of Ppp1r1b 1 0.06 0 0.44
9 INT94362 OPRD1 Positive_regulation of PPP1R1A 1 0.29 0.16 0.44
10 INT196821 Phosphorylation of Ppp1r1b Positive_regulation of Prkaca 1 0.09 0 0.41
11 INT112919 Nts Negative_regulation of Phosphorylation of Ppp1r1b 1 0.28 0 0.4
12 INT196829 Ppp1r1b Negative_regulation of Phosphorylation of Ppp1cc 1 0.07 0 0.39
13 INT196796 Ppp1r1b Negative_regulation of Phosphorylation of Trh 1 0.01 0 0.39
14 INT196798 Trh Positive_regulation of Phosphorylation of Ppp1r1b 1 0.01 0 0.3
15 INT337113 Ppp1r1b Negative_regulation of Phosphorylation of Cdk5 1 0.11 0.28 0.27
16 INT276046 Negative_regulation of Prkaca Positive_regulation of Phosphorylation of Ppp1r1b 1 0.15 0.11 0.23
17 INT112913 Nts Positive_regulation of Phosphorylation of Ppp1r1b 1 0.53 0 0.18
18 INT276069 Binding of Camk2a and Ppp1r1b 1 0.18 0 0.12
19 INT276057 Binding of Prkaca and Ppp1r1b 1 0.10 0 0.12
20 INT276033 Binding of Ppp1cc and Ppp1r1b 1 0.06 0 0.09
21 INT276070 Negative_regulation of Pde1b Positive_regulation of Phosphorylation of Ppp1r1b 1 0.24 0 0.03
22 INT327447 Binding of REN and Positive_regulation of PPP1R1A 1 0.43 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for protein serine/threonine phosphatase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported in protein serine/threonine phosphatase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT112908 Phosphorylation of Ppp1r1b 65 0.77 1.27 16.42
2 INT138348 Positive_regulation of Phosphorylation of Ppp1r1b 16 0.56 1.4 4.63
3 INT113137 Positive_regulation of Ppp1r1b 14 0.65 0.89 4.21
4 INT196736 Gene_expression of Ppp1r1b 24 0.55 2.01 3.99
5 INT112907 Regulation of Phosphorylation of Ppp1r1b 11 0.21 0.06 3.15
6 INT100812 Phosphorylation of PPP1R14C 1 0.71 0 2.45
7 INT51106 Gene_expression of PPP1R1A 5 0.67 1.76 1.99
8 INT196784 Regulation of Ppp1r1b 8 0.32 0.3 1.78
9 INT112904 Negative_regulation of Ppp1r1b 3 0.34 0.1 1.29
10 INT113136 Positive_regulation of Positive_regulation of Ppp1r1b 2 0.47 0 1.25
11 INT100814 Gene_expression of PPP1R14C 1 0.58 0 1.23
12 INT48282 Binding of PPP1R1A 4 0.48 0.09 0.91
13 INT112906 Negative_regulation of Phosphorylation of Ppp1r1b 5 0.55 0 0.86
14 INT48283 Localization of PPP1R1A 2 0.78 1.44 0.8
15 INT228844 Regulation of Gene_expression of Ppp1r1b 3 0.32 0.17 0.77
16 INT127910 Negative_regulation of PPP1R1A 1 0.02 0.15 0.75
17 INT100815 Positive_regulation of Gene_expression of PPP1R14C 1 0.52 0 0.66
18 INT51107 Positive_regulation of PPP1R1A 2 0.49 1.32 0.65
19 INT100811 Positive_regulation of PPP1R14C 1 0.35 0 0.62
20 INT66443 Regulation of Gene_expression of PPP1R1A 2 0.35 0.35 0.57
21 INT100813 Regulation of Gene_expression of PPP1R14C 1 0.46 0 0.57
22 INT235840 Negative_regulation of Gene_expression of Ppp1r1b 1 0.09 0.19 0.57
23 INT100809 Transcription of PPP1R14C 1 0.40 0 0.57
24 INT100808 Regulation of Phosphorylation of PPP1R14C 1 0.34 0 0.57
25 INT196774 Positive_regulation of Gene_expression of Ppp1r1b 4 0.31 0.29 0.56
26 INT196738 Binding of Ppp1r1b 3 0.26 0.27 0.53
27 INT100807 Regulation of PPP1R14C 1 0.20 0 0.44
28 INT139645 Positive_regulation of Negative_regulation of Ppp1r1b 1 0.17 0.1 0.27
29 INT228847 Localization of Ppp1r1b 2 0.53 0.25 0.07
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