GO:0004869

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Name cysteine-type endopeptidase inhibitor activity
Categary Function
Go Slim No
Go Link GO:0004869
Unique Molecular Interactions 191
Total Molecular Interactions 219
Total Single Events 2414
Pain Genes Associated 18

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cysteine-type endopeptidase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported for cysteine-type endopeptidase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
2 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
3 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
4 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
5 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
6 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
7 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
8 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
9 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
10 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
11 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
12 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
13 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
14 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
15 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
16 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
17 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
18 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
19 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
20 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
21 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
22 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83
23 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79
24 INT328976 Binding of Cst7 and Cts 1 0.08 0.92 0.79
25 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
26 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
27 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75
28 INT328980 Binding of Cst7 and Igfals 1 0.06 0.85 0.73
29 INT328983 Binding of Cst7 and Muted 1 0.04 0.84 0.73
30 INT328977 Binding of Cst7 and Mup1 1 0.18 0.84 0.73
31 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69
32 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
33 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
34 INT95546 KNG1 Positive_regulation of Ptgir 1 0.02 0.93 0.64
35 INT96472 KNG1 Positive_regulation of Gene_expression of TRPV1 1 0.01 0.22 0.64
36 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63
37 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
38 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
39 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62
40 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61
41 INT34840 Binding of KNG1 and PDYN 1 0.01 0 0.61
42 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
43 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
44 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
45 INT303721 KNG1 Positive_regulation of Bdkrb1 1 0.05 0.75 0.52
46 INT172248 Binding of KNG1 and NCOR2 1 0.02 0.19 0.52
47 INT303722 KNG1 Positive_regulation of Bdkrb2 1 0.01 0.7 0.52
48 INT33415 KNG1 Positive_regulation of GBP1 1 0.02 0.43 0.51
49 INT118485 CST3 Regulation of CTSH 1 0.36 0 0.49
50 INT58663 Binding of KNG1 and Ugt1a2 1 0.02 0.4 0.47
51 INT327090 Negative_regulation of F12 Negative_regulation of Gene_expression of KNG1 1 0.00 0.51 0.45
52 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
53 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
54 INT201092 Binding of KNG1 and NGF 1 0.00 0.31 0.43
55 INT201120 Binding of KNG1 and Par2 1 0.00 0.3 0.42
56 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41
57 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41
58 INT85511 Binding of KNG1 and Bdkrb2 1 0.54 0.51 0.4
59 INT229222 Negative_regulation of ACE Negative_regulation of Protein_catabolism of KNG1 1 0.06 0.53 0.37
60 INT291625 Binding of CSTA and RAPGEF5 1 0.03 4.81 0.37
61 INT26552 Gene_expression of Mras Positive_regulation of Gene_expression of KNG1 1 0.03 0.07 0.36
62 INT136007 Binding of INSRR and KNG1 1 0.00 0.17 0.34
63 INT230855 KNG1 Regulation of NOS1 2 0.03 0.94 0.33
64 INT230852 ACE Regulation of KNG1 2 0.03 0.72 0.32
65 INT35216 Binding of KNG1 and Thop1 1 0.01 0 0.32
66 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32
67 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
68 INT196618 Binding of KNG1 and Positive_regulation of NA 1 0.01 0.19 0.32
69 INT196623 Binding of KNG1 and Positive_regulation of DNAH8 1 0.01 0.19 0.32
70 INT170994 KNG1 Positive_regulation of Gene_expression of IL8 1 0.04 0.45 0.32
71 INT28688 Binding of Kng1 and Ctsl1 1 0.15 0 0.31
72 INT137308 sps Negative_regulation of Cstb 1 0.03 1.59 0.31
73 INT291568 Artles Regulation of Cstb 1 0.00 0.7 0.3
74 INT66243 KNG1 Positive_regulation of Ptgis 1 0.01 0 0.3
75 INT44984 KNG1 Regulation of Ltc4s 1 0.01 0.17 0.3
76 INT196641 Binding of KNG1 and Negative_regulation of DNAH8 1 0.01 0.19 0.29
77 INT196612 Binding of KNG1 and Negative_regulation of NA 1 0.01 0.19 0.29
78 INT196626 Binding of DNAH8 and KNG1 1 0.00 0.08 0.27
79 INT196613 Binding of KNG1 and NA 1 0.01 0.08 0.27
80 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27
81 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
82 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25
83 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25
84 INT64726 Ace Negative_regulation of KNG1 1 0.01 0.26 0.25
85 INT64727 Ace Positive_regulation of KNG1 1 0.01 0.26 0.25
86 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24
87 INT239238 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.01 0.46 0.24
88 INT265828 ACE Regulation of Gene_expression of KNG1 1 0.32 0.83 0.22
89 INT128986 Binding of CST3 and Phdlc1 1 0.01 1.96 0.22
90 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22
91 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21
92 INT82094 Binding of KNG1 and CLPP 1 0.03 0.42 0.21
93 INT281903 BDKRB1 Positive_regulation of KNG1 1 0.03 0.32 0.21
94 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19
95 INT257844 STS Positive_regulation of Negative_regulation of CST7 1 0.01 0.24 0.19
96 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18
97 INT266046 Cstb Regulation of Gene_expression of Adrm1 1 0.00 0.7 0.18
98 INT329324 KNG1 Positive_regulation of Localization of ecs 1 0.00 1.16 0.17
99 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 0.00 0.46 0.17
100 INT77159 Positive_regulation of KLK1 Positive_regulation of KNG1 1 0.04 0.28 0.15
101 INT128705 Binding of Adrb2 and Ahsg 1 0.00 0.23 0.15
102 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14
103 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14
104 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13
105 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13
106 INT107635 KNG1 Regulation of Slc25a1 1 0.00 0.1 0.13
107 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13
108 INT107622 KNG1 Regulation of AP4B1 1 0.19 0.1 0.13
109 INT221254 Binding of KNG1 and Akt1 1 0.00 0.13 0.13
110 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12
111 INT182368 IgG Regulation of Cast 1 0.01 0.99 0.11
112 INT291622 HSD11B1 Regulation of CSTA 1 0.00 0.6 0.11
113 INT229364 Ace Positive_regulation of Protein_catabolism of KNG1 1 0.02 0.86 0.11
114 INT196619 KNG1 Regulation of DNAH8 1 0.00 0.62 0.09
115 INT265829 ACE Positive_regulation of Protein_catabolism of KNG1 1 0.33 0.73 0.09
116 INT291624 SERPINH1 Regulation of CSTA 1 0.00 0.39 0.09
117 INT196645 KNG1 Regulation of NA 1 0.00 0.62 0.09
118 INT189957 Binding of LDHA and Pttg1 1 0.05 0.35 0.08
119 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
120 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
121 INT128706 Binding of MET and Ahsg 1 0.28 0.34 0.07
122 INT275126 Binding of CSTB and IGHG3 1 0.00 0.49 0.05
123 INT262781 Birc5 Regulation of TEP1 1 0.00 0.49 0.05
124 INT262780 Birc5 Regulation of CD163L1 1 0.00 0.49 0.05
125 INT232009 Positive_regulation of F12 Negative_regulation of Localization of KNG1 1 0.01 0.19 0.05
126 INT253023 Binding of PTTG1 and Myc 1 0.16 0.22 0.04
127 INT252897 Binding of PTTG1IP and PTTG1 1 0.04 0.15 0.04
128 INT252892 PTTG1IP Regulation of PTTG1 1 0.05 0.49 0.04
129 INT202270 Pttg1 Positive_regulation of Myc 1 0.28 0.84 0.03
130 INT291621 RAPGEF5 Regulation of CSTA 1 0.04 0.43 0.03
131 INT253010 Binding of PTTG1 and Fgf2 1 0.07 0.51 0.03
132 INT292505 PTK2 Regulation of Birc5 1 0.29 0.76 0
133 INT253003 Pttg1 Regulation of Gene_expression of Id3 1 0.08 0.07 0
134 INT129874 Binding of CST3 and CTSS 1 0.42 2.45 0
135 INT165187 Positive_regulation of Binding of CST3 and IL18 1 0.03 0.28 0
136 INT253004 Anapc1 Positive_regulation of Binding of Pttg1 1 0.47 0 0
137 INT292515 LAMB2 Positive_regulation of Birc5 1 0.01 0.7 0
138 INT218506 Binding of LCN1 and Cfb 1 0.04 0.25 0
139 INT236246 Binding of CD8A and Birc5 1 0.04 1.34 0
140 INT292512 AKT1 Regulation of Birc5 1 0.08 0.76 0
141 INT252910 PTTG1 Negative_regulation of Transcription of SLC5A5 1 0.02 0.36 0
142 INT253011 Negative_regulation of Binding of PTTG1 and Zic2 1 0.01 0.41 0
143 INT253021 PTTG1 Regulation of Gene_expression of Fgf2 1 0.04 0.35 0
144 INT252906 Binding of SLC5A5 and PTTG1 1 0.01 0.69 0
145 INT253007 Igf1 Regulation of Gene_expression of PTTG1 1 0.03 0.46 0
146 INT273950 Binding of Crem and Cst8 1 0.10 0 0
147 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0
148 INT237980 CCND3 Regulation of Gene_expression of Birc5 1 0.06 0.96 0
149 INT283822 BC100530 Positive_regulation of Stfa1 1 0.53 0 0
150 INT253018 Binding of PTTG1 and Zic2 1 0.01 0.76 0
151 INT324305 Binding of CST3 and UMOD 1 0.05 3.22 0
152 INT236241 Binding of Birc5 and Ifna 1 0.05 0.31 0
153 INT187575 TP53 Regulation of Gene_expression of Birc5 1 0.05 1.1 0
154 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0
155 INT253008 PTTG1 Regulation of Gene_expression of Id3 1 0.03 0.2 0
156 INT252900 PTTG1 Regulation of Gene_expression of TAF9 1 0.20 0.84 0
157 INT253020 Pttg1 Negative_regulation of THBS1 1 0.03 0.16 0
158 INT253019 APC Positive_regulation of Protein_catabolism of Pttg1 1 0.06 0 0
159 INT218532 Binding of C5 and LCN1 1 0.06 0.49 0
160 INT253012 APC Positive_regulation of Binding of Pttg1 1 0.06 0 0
161 INT253016 Binding of PTTG1 and Id3 1 0.04 0.07 0
162 INT298436 Binding of KNG1 and SNAI1 1 0.09 0.53 0
163 INT252896 INS Regulation of Gene_expression of PTTG1 1 0.00 0.47 0
164 INT187574 Binding of TP53 and Birc5 1 0.04 1.27 0
165 INT189956 TP53 Positive_regulation of Gene_expression of Pttg1 1 0.06 1.21 0
166 INT145556 Binding of CST3 and TNNI3 1 0.25 0.11 0
167 INT187576 BAX Regulation of Gene_expression of Birc5 1 0.06 1.1 0
168 INT298435 Binding of ITK and KNG1 1 0.01 0.58 0
169 INT249828 Foxm1 Positive_regulation of Transcription of BIRC5 1 0.56 0.12 0
170 INT324309 Binding of CST3 and GATM 1 0.00 1.6 0
171 INT252907 Binding of PTTG1 and PTTG2 1 0.07 0.08 0
172 INT252893 PTTG1 Positive_regulation of Gene_expression of TAF9 1 0.21 0.9 0
173 INT165189 Binding of CST3 and IL18 1 0.02 0.28 0
174 INT144042 STAT3 Regulation of Birc5 1 0.47 0.06 0
175 INT348935 Binding of KNG1 and ERLEC1 1 0.03 0.48 0
176 INT291623 Binding of CRP and CSTA 1 0.03 0.38 0
177 INT253005 Binding of Zic2 and Pttg1 1 0.02 0.57 0
178 INT283820 BC117090 Positive_regulation of Stfa1 1 0.53 0 0
179 INT349355 CSF2 Negative_regulation of CSTA 1 0.01 1.43 0
180 INT252899 PTTG1 Regulation of Gene_expression of SLC5A5 1 0.01 0.43 0
181 INT253022 PTTG1 Negative_regulation of Negative_regulation of Trp53 1 0.03 1.34 0
182 INT193119 Trp53 Regulation of Birc5 1 0.19 0.55 0
183 INT253006 Anapc1 Positive_regulation of Protein_catabolism of Pttg1 1 0.51 0 0
184 INT252895 PTTG1 Regulation of Gene_expression of VEGFA 1 0.03 0.15 0
185 INT292492 Mlph Regulation of Gene_expression of Birc5 1 0.04 1.11 0
186 INT237979 PPARA Negative_regulation of Birc5 1 0.49 1.26 0
187 INT324308 Binding of CST3 and SHROOM3 1 0.04 1.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cysteine-type endopeptidase inhibitor activity. They are ordered first by their pain relevance and then by number of times they were reported in cysteine-type endopeptidase inhibitor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
2 INT7134 Localization of KNG1 127 0.79 65.73 67.97
3 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
4 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
5 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
6 INT3167 Binding of KNG1 48 0.48 23.26 26.77
7 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3
8 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
9 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
10 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
11 INT100661 Regulation of Cst7 18 0.53 5.93 7.8
12 INT677 Positive_regulation of CST3 20 0.67 17.47 6
13 INT55101 Gene_expression of Cst7 16 0.75 2.39 5.92
14 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73
15 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5
16 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16
17 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
18 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9
19 INT49217 Positive_regulation of Positive_regulation of KNG1 7 0.41 3.64 4.18
20 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
21 INT27466 Negative_regulation of Kng1 7 0.10 7.79 3.56
22 INT220078 Positive_regulation of Negative_regulation of KNG1 3 0.13 5.03 3.41
23 INT107962 Gene_expression of Pttg1 34 0.53 34.05 3.11
24 INT37405 Positive_regulation of Cst7 7 0.49 3.32 2.99
25 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
26 INT61904 Gene_expression of CST7 3 0.53 3.22 2.53
27 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
28 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
29 INT640 Regulation of CST3 9 0.60 4.04 2.26
30 INT150640 Regulation of Binding of KNG1 3 0.35 1.31 2.2
31 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17
32 INT8237 Positive_regulation of Kng1 16 0.69 4.41 2.12
33 INT130754 Gene_expression of Cast 21 0.78 11.6 2.08
34 INT11745 Protein_catabolism of Cst7 3 0.39 0.81 2.08
35 INT242856 Binding of Cst7 2 0.18 3.04 1.93
36 INT88375 Negative_regulation of Localization of KNG1 4 0.39 1.12 1.91
37 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87
38 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87
39 INT62349 Negative_regulation of Protein_catabolism of KNG1 8 0.42 6.47 1.86
40 INT146338 Positive_regulation of Cstb 4 0.38 4.25 1.64
41 INT74818 Transcription of KNG1 6 0.67 2.71 1.59
42 INT60975 Localization of CST3 6 0.78 2.4 1.58
43 INT107132 Regulation of Localization of KNG1 2 0.22 0.96 1.55
44 INT189948 Gene_expression of Pttg1 106 0.76 104.68 1.41
45 INT37076 Negative_regulation of Binding of KNG1 3 0.14 1.77 1.32
46 INT53252 Gene_expression of Kng1 7 0.67 2.18 1.27
47 INT679 Negative_regulation of CST3 7 0.57 4.63 1.22
48 INT130755 Positive_regulation of Gene_expression of Cast 4 0.70 4.3 1.18
49 INT48338 Gene_expression of Ahsg 2 0.52 0.25 1.16
50 INT36064 Binding of CST3 14 0.47 16.38 1.12
51 INT107961 Positive_regulation of Gene_expression of Pttg1 2 0.38 11.69 1.09
52 INT150638 Positive_regulation of Binding of KNG1 1 0.39 0.24 1.07
53 INT202264 Positive_regulation of Pttg1 8 0.45 8.03 1.04
54 INT36580 Positive_regulation of LCN1 9 0.45 5.63 1.02
55 INT68844 Regulation of Positive_regulation of KNG1 2 0.44 2.22 1.02
56 INT106152 Negative_regulation of Regulation of Cst7 1 0.36 0.69 0.99
57 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96
58 INT191530 Regulation of Gene_expression of KNG1 4 0.26 0.71 0.96
59 INT63037 Regulation of CSTA 10 0.37 13.37 0.92
60 INT114340 Positive_regulation of Protein_catabolism of KNG1 5 0.07 2.42 0.92
61 INT55102 Positive_regulation of Gene_expression of Cst7 1 0.41 0.05 0.89
62 INT27467 Localization of Kng1 2 0.76 0.78 0.87
63 INT33495 Regulation of Ahsg 1 0.23 0 0.86
64 INT48339 Regulation of Localization of Ahsg 1 0.21 0 0.86
65 INT48337 Localization of Ahsg 1 0.54 0 0.85
66 INT175106 Gene_expression of LCN1 6 0.75 4.59 0.83
67 INT239234 Regulation of Protein_catabolism of KNG1 2 0.09 1.06 0.82
68 INT37118 Regulation of Kng1 3 0.49 1.09 0.77
69 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74
70 INT127487 Phosphorylation of KNG1 2 0.34 0.47 0.74
71 INT109603 Positive_regulation of Localization of CST3 1 0.45 0.61 0.67
72 INT89363 Positive_regulation of Ahsg 2 0.11 1.11 0.63
73 INT156404 Negative_regulation of Pttg1 2 0.23 4.06 0.62
74 INT125553 Negative_regulation of Positive_regulation of Cst7 1 0.37 0.55 0.62
75 INT184185 Transcription of Kng1 1 0.05 1.66 0.62
76 INT159551 Regulation of Cstb 4 0.06 2.46 0.61
77 INT53251 Positive_regulation of Gene_expression of Kng1 2 0.60 0.71 0.58
78 INT63035 Gene_expression of CSTA 10 0.56 11.56 0.57
79 INT55662 Negative_regulation of Negative_regulation of KNG1 4 0.36 3.45 0.57
80 INT182317 Binding of Birc5 8 0.32 4.63 0.56
81 INT193108 Negative_regulation of Negative_regulation of Birc5 6 0.42 5.25 0.53
82 INT202259 Transcription of Pttg1 1 0.34 4.13 0.53
83 INT137412 Negative_regulation of Cast 6 0.49 4.03 0.52
84 INT150323 Gene_expression of Cstb 5 0.67 3.31 0.52
85 INT183918 Negative_regulation of Gene_expression of Kng1 1 0.04 1.16 0.51
86 INT182315 Positive_regulation of Negative_regulation of Birc5 2 0.45 1.79 0.46
87 INT257849 Binding of CST7 2 0.18 0 0.44
88 INT223880 Positive_regulation of Negative_regulation of Cst7 1 0.40 0 0.43
89 INT137410 Positive_regulation of Cast 4 0.70 4.37 0.39
90 INT189946 Positive_regulation of Gene_expression of Pttg1 14 0.68 23.72 0.38
91 INT182314 Transcription of Birc5 4 0.69 2.69 0.37
92 INT89367 Negative_regulation of Ahsg 2 0.14 0.85 0.36
93 INT184187 Negative_regulation of Binding of Kng1 1 0.03 1.07 0.36
94 INT184186 Binding of Kng1 1 0.03 1.06 0.36
95 INT252989 Localization of PTTG1 1 0.32 1.49 0.36
96 INT182319 Localization of Birc5 6 0.75 5.13 0.34
97 INT202268 Regulation of Gene_expression of Pttg1 3 0.33 3.1 0.34
98 INT175097 Localization of LCN1 3 0.73 2.07 0.33
99 INT109604 Negative_regulation of Localization of CST3 1 0.41 0.31 0.31
100 INT137409 Negative_regulation of Positive_regulation of Cast 1 0.38 0.95 0.3
101 INT74817 Positive_regulation of Transcription of KNG1 1 0.49 0.18 0.3
102 INT202269 Regulation of Pttg1 3 0.33 2.47 0.27
103 INT165579 Regulation of Gene_expression of Ahsg 1 0.01 0.25 0.26
104 INT257848 Regulation of CST7 1 0.22 0.28 0.26
105 INT165577 Positive_regulation of Gene_expression of Ahsg 1 0.04 0.25 0.26
106 INT189953 Regulation of PTTG1 2 0.18 6.45 0.25
107 INT63036 Negative_regulation of CSTA 4 0.36 9.42 0.22
108 INT218547 Regulation of Negative_regulation of Cst7 1 0.05 0.49 0.22
109 INT218548 Regulation of Gene_expression of Cst7 1 0.09 0.49 0.22
110 INT20608 Positive_regulation of Regulation of CST3 1 0.01 1.23 0.21
111 INT266061 Negative_regulation of Cstb 1 0.03 1.29 0.2
112 INT85392 Negative_regulation of LCN1 3 0.42 0.73 0.19
113 INT257847 Positive_regulation of Negative_regulation of CST7 1 0.24 0.24 0.19
114 INT178547 Gene_expression of CSTB 9 0.29 6.53 0.18
115 INT252977 Positive_regulation of PTTG1 1 0.28 8.39 0.18
116 INT137411 Negative_regulation of Gene_expression of Cast 4 0.49 2.38 0.17
117 INT194322 Positive_regulation of CST7 1 0.32 0.39 0.17
118 INT193114 Positive_regulation of Positive_regulation of Birc5 1 0.45 0.33 0.17
119 INT189945 Localization of Pttg1 3 0.73 3.02 0.16
120 INT245655 Regulation of Gene_expression of Cast 2 0.38 0.44 0.16
121 INT180530 Positive_regulation of Positive_regulation of LCN1 1 0.04 1.06 0.16
122 INT202260 Regulation of Transcription of Pttg1 1 0.21 1.13 0.16
123 INT212567 Negative_regulation of Gene_expression of Cstb 1 0.06 0.72 0.15
124 INT193104 Positive_regulation of Regulation of Birc5 1 0.49 1.61 0.15
125 INT182316 Positive_regulation of Localization of Birc5 1 0.02 0.99 0.13
126 INT218545 Positive_regulation of Localization of Cst7 1 0.10 0.99 0.13
127 INT266055 Positive_regulation of Gene_expression of Cstb 1 0.03 0.8 0.13
128 INT218546 Localization of Cst7 1 0.15 0.99 0.13
129 INT243382 Positive_regulation of CSTA 4 0.05 14.65 0.12
130 INT202262 Negative_regulation of Gene_expression of Pttg1 2 0.25 1.57 0.12
131 INT291629 Localization of CSTA 1 0.08 1.05 0.11
132 INT169045 Gene_expression of Cst8 1 0.34 0.17 0.11
133 INT202263 Regulation of Protein_catabolism of Pttg1 1 0.15 0.96 0.1
134 INT202261 Protein_catabolism of Pttg1 1 0.54 1.52 0.1
135 INT202265 Positive_regulation of Protein_catabolism of Pttg1 1 0.38 0.95 0.1
136 INT193106 Phosphorylation of Birc5 3 0.80 2.13 0.09
137 INT239095 Negative_regulation of PTTG1 2 0.32 8.24 0.09
138 INT250670 Negative_regulation of Phosphorylation of Birc5 2 0.57 1.17 0.09
139 INT314778 Regulation of Binding of CST3 1 0.26 1.5 0.09
140 INT678 Regulation of Negative_regulation of CST3 1 0.39 0.09 0.09
141 INT266059 Negative_regulation of Transcription of Cstb 1 0.03 0.49 0.09
142 INT247941 Binding of Cast 1 0.30 0.45 0.09
143 INT307773 Regulation of Negative_regulation of KNG1 1 0.01 3.59 0.09
144 INT41924 Phosphorylation of CST3 1 0.57 0.23 0.09
145 INT266060 Transcription of Cstb 1 0.04 0.49 0.09
146 INT291628 Positive_regulation of Gene_expression of CSTA 1 0.05 0.52 0.09
147 INT291630 Regulation of Gene_expression of CSTA 2 0.06 1.01 0.08
148 INT202266 Binding of Pttg1 2 0.29 1.37 0.08
149 INT291627 Binding of CSTA 2 0.04 1.58 0.08
150 INT193111 Protein_catabolism of Birc5 2 0.86 1.01 0.08
151 INT238499 Negative_regulation of BIRC5 1 0.23 1.66 0.08
152 INT193115 Regulation of Protein_catabolism of Birc5 1 0.44 0.14 0.08
153 INT39981 Positive_regulation of Binding of CST3 1 0.43 0.71 0.08
154 INT262749 Negative_regulation of Transcription of Birc5 1 0.02 1.37 0.07
155 INT178535 Regulation of Gene_expression of CSTB 2 0.19 2.91 0.06
156 INT169043 Localization of Cst8 1 0.38 0.17 0.05
157 INT37119 Positive_regulation of Positive_regulation of Kng1 1 0.46 0.17 0.05
158 INT169044 Positive_regulation of Cst8 1 0.22 0.18 0.05
159 INT252992 Regulation of Gene_expression of PTTG1 1 0.18 5.07 0.04
160 INT252980 Binding of PTTG1 1 0.19 0.59 0.04
161 INT275147 Binding of CSTB 2 0.04 0.94 0.03
162 INT128703 Binding of Ahsg 1 0.26 0.17 0.03
163 INT194323 Transcription of CST7 1 0.48 0 0.03
164 INT275142 Negative_regulation of Binding of CSTB 1 0.04 0.66 0.03
165 INT252966 Negative_regulation of Gene_expression of PTTG1 1 0.23 2.7 0.03
166 INT288241 Regulation of Gene_expression of CST3 1 0.44 0.28 0.03
167 INT178536 Regulation of CSTB 1 0.19 1.17 0.03
168 INT252979 Positive_regulation of Localization of PTTG1 1 0.20 0.18 0.03
169 INT275597 Regulation of Negative_regulation of LCN1 1 0.16 0.23 0.03
170 INT189944 Negative_regulation of Gene_expression of Pttg1 4 0.42 4.53 0
171 INT189947 Regulation of Pttg1 4 0.49 7.18 0
172 INT175098 Binding of LCN1 3 0.37 0.38 0
173 INT273930 Binding of Cst8 2 0.07 0.09 0
174 INT189952 Transcription of PTTG1 2 0.21 1.6 0
175 INT189951 Binding of Pttg1 2 0.44 1.16 0
176 INT189943 Negative_regulation of Pttg1 2 0.53 5.8 0
177 INT349357 Negative_regulation of Transcription of CSTA 1 0.02 1.26 0
178 INT348072 Localization of CSTB 1 0.08 0.18 0
179 INT283807 Negative_regulation of Gene_expression of Stfa1 1 0.41 0 0
180 INT252948 Positive_regulation of Protein_catabolism of Pttg1 1 0.63 0.09 0
181 INT252949 Negative_regulation of Negative_regulation of Pttg1 1 0.39 0.34 0
182 INT245660 Positive_regulation of Phosphorylation of Cast 1 0.31 0.13 0
183 INT249820 Transcription of BIRC5 1 0.67 0.12 0
184 INT249818 Gene_expression of BIRC5 1 0.65 0.12 0
185 INT245666 Negative_regulation of Phosphorylation of Cast 1 0.26 0.13 0
186 INT349361 Negative_regulation of Gene_expression of CSTA 1 0.02 1.57 0
187 INT130135 Regulation of Localization of CST3 1 0.26 0 0
188 INT252952 Protein_catabolism of Pttg1 1 0.91 0.09 0
189 INT252944 Positive_regulation of Pttg1 1 0.46 2.53 0
190 INT275144 Negative_regulation of Gene_expression of CSTB 1 0.04 0.39 0
191 INT252938 Phosphorylation of Pttg1 1 0.75 1.11 0
192 INT245661 Positive_regulation of Negative_regulation of Cast 1 0.31 0 0
193 INT349362 Transcription of CSTA 1 0.02 1.38 0
194 INT294807 Regulation of Negative_regulation of Birc5 1 0.45 1.05 0
195 INT349359 Regulation of Transcription of CSTA 1 0.01 0.15 0
196 INT252957 Regulation of Binding of Pttg1 1 0.41 0.64 0
197 INT283794 Positive_regulation of Gene_expression of Stfa1 1 0.48 0.11 0
198 INT189950 Transcription of Pttg1 1 0.70 2.38 0
199 INT249819 Positive_regulation of Gene_expression of BIRC5 1 0.49 0.12 0
200 INT252958 Positive_regulation of Localization of Pttg1 1 0.37 0 0
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