GO:0004879

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Name ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
Categary Function
Go Slim No
Go Link GO:0004879
Unique Molecular Interactions 1233
Total Molecular Interactions 1619
Total Single Events 16506
Pain Genes Associated 64

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported for ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
3 INT129903 Nr1i2 Regulation of Cyp3a11 1 0.64 1.26 1.9
4 INT162105 Nr4a3 Regulation of ACPT-I 1 0.10 0.26 1.38
5 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
6 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
7 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
8 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
9 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
10 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
11 INT200307 Rest Negative_regulation of Rorb 1 0.00 0.1 1.03
12 INT209923 IL17A Negative_regulation of PPARA 1 0.14 2.46 0.99
13 INT136420 Binding of DeltaFosB and Rorb 1 0.03 0.66 0.97
14 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
15 INT22726 Positive_regulation of Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
16 INT22725 Ahr Positive_regulation of Hrtrt1 1 0.22 0.18 0.95
17 INT262165 Nr0b2 Negative_regulation of Nr5a2 1 0.02 0.5 0.92
18 INT128860 NR1H4 Negative_regulation of Gene_expression of OPRM1 1 0.15 0.31 0.92
19 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
20 INT200308 Binding of Rest and Rorb 1 0.00 0 0.87
21 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
22 INT158068 Positive_regulation of Pparg Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.28 0.76
23 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75
24 INT98956 Positive_regulation of Binding of NR5A2 and SP1 1 0.00 0 0.7
25 INT98951 Positive_regulation of Binding of NR5A2 and SP3 1 0.00 0 0.7
26 INT98957 Binding of NR5A2 and SP3 1 0.00 0 0.7
27 INT98958 Binding of NR5A2 and SP1 1 0.00 0 0.7
28 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
29 INT209859 IL4 Positive_regulation of PPARA 1 0.22 1.66 0.69
30 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
31 INT197233 Positive_regulation of Rora Positive_regulation of Localization of Helt 1 0.00 0 0.68
32 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
33 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
34 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
35 INT200300 Binding of Nenf and Rorb 1 0.00 0 0.64
36 INT153797 NUBPL Negative_regulation of PPARD 1 0.02 0.69 0.64
37 INT114950 YY1 Positive_regulation of Positive_regulation of PPARA 1 0.52 0.25 0.64
38 INT113146 Ddc Positive_regulation of Gene_expression of Nr4a1 1 0.06 0.1 0.63
39 INT114948 NCOA1 Positive_regulation of Positive_regulation of PPARA 1 0.20 0.24 0.62
40 INT231027 LOC100366054 Negative_regulation of Gene_expression of Pgr 1 0.02 0 0.62
41 INT2687 Negative_regulation of Binding of Thra and SGSM3 1 0.43 0.1 0.62
42 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
43 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
44 INT2686 Binding of Thra and SGSM3 1 0.36 0.1 0.61
45 INT148257 NR4A2 Regulation of Gene_expression of SLC6A3 1 0.60 0.4 0.59
46 INT208372 Il13 Positive_regulation of Ahr 1 0.21 1.22 0.59
47 INT2685 S100A6 Positive_regulation of Regulation of Thra 1 0.47 0.09 0.58
48 INT2684 S100A6 Regulation of Regulation of Thra 1 0.45 0.09 0.58
49 INT177269 Binding of CXADR and NR1H4 1 0.04 0 0.58
50 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
51 INT147575 Binding of Ahr and Cyp1a1 2 0.15 0.15 0.54
52 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54
53 INT103092 Binding of PPARA and ISYNA1 1 0.01 0.45 0.54
54 INT335514 NR1I2 Regulation of Gene_expression of ABCB1 1 0.66 2.42 0.54
55 INT310701 RPLP0 Regulation of Positive_regulation of PGR 1 0.01 0.49 0.53
56 INT55445 Positive_regulation of Ahr Regulation of Mme 1 0.23 0 0.53
57 INT231034 Sec22b Positive_regulation of Gene_expression of Pgr 1 0.04 0.09 0.53
58 INT147576 Positive_regulation of Ahr Positive_regulation of Gene_expression of Scrg1 1 0.00 0.17 0.52
59 INT162500 AHR Regulation of CYP1A1 3 0.19 0.18 0.51
60 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
61 INT162503 AHR Regulation of CYP1A2 3 0.61 0.18 0.5
62 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
63 INT285688 Cpox Positive_regulation of PPARA 1 0.02 1 0.5
64 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
65 INT162499 Binding of AHR and NEUROD1 3 0.25 0.19 0.49
66 INT121944 Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.78 0.43 0.49
67 INT153330 Binding of PTGER3 and Cm9 1 0.36 0.15 0.48
68 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47
69 INT309135 Edc4 Regulation of Positive_regulation of Rorb 1 0.00 0.54 0.47
70 INT185917 Binding of AR and MAPK1 1 0.07 0.5 0.47
71 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
72 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46
73 INT262155 Nr5a2 Positive_regulation of Cyp7a1 1 0.07 0.24 0.45
74 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44
75 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44
76 INT262220 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Abcc2 1 0.14 0.25 0.44
77 INT73660 Rorb Regulation of Gene_expression of Pdyn 1 0.04 0.49 0.44
78 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44
79 INT193217 Binding of PTGER2 and PTGER3 2 0.10 1.31 0.43
80 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43
81 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
82 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42
83 INT107703 PPARG Regulation of Gene_expression of CPOX 1 0.16 0.15 0.41
84 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
85 INT238382 Il13 Positive_regulation of Gene_expression of Ppara 1 0.18 0.79 0.4
86 INT107706 PPARA Positive_regulation of Gene_expression of CPOX 1 0.18 0.14 0.4
87 INT236110 Binding of Ppara and Olfm4 1 0.00 1.22 0.4
88 INT139047 Negative_regulation of AR Negative_regulation of Positive_regulation of CPOX 1 0.07 0.76 0.4
89 INT200303 Oprm1 Negative_regulation of Rorb 1 0.00 0.1 0.39
90 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
91 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38
92 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
93 INT262205 Positive_regulation of Nr1i2 Positive_regulation of Gene_expression of Cyp3a11 1 0.33 0.11 0.38
94 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
95 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 0.17 1.19 0.38
96 INT200301 Sp3 Regulation of Rorb 1 0.00 0.07 0.38
97 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38
98 INT200302 Rest Regulation of Rorb 1 0.00 0.07 0.38
99 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
100 INT297426 Stat6 Regulation of Ppara 1 0.17 1.19 0.38
101 INT262153 Binding of Clta and Nr1i2 1 0.05 0.65 0.38
102 INT300610 Rorb Regulation of Dnm2 1 0.01 0.27 0.37
103 INT337890 Per1 Regulation of Nr2f2 1 0.08 0 0.37
104 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
105 INT265015 Pgr Positive_regulation of Sds 1 0.04 0.49 0.37
106 INT235432 Ppara Negative_regulation of Gene_expression of Cpox 1 0.01 1 0.37
107 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
108 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37
109 INT245328 Binding of Esr2 and Pgr 1 0.03 0.41 0.37
110 INT262182 Positive_regulation of Nr1i2 Negative_regulation of Gene_expression of Cyp7a1 1 0.23 0.36 0.36
111 INT262189 Binding of Nr1i2 and Nr1h4 1 0.14 0.18 0.36
112 INT90722 Nr4a1 Positive_regulation of Egr1 1 0.20 0.48 0.35
113 INT106998 PAR4 Positive_regulation of NR1I2 1 0.22 0.67 0.35
114 INT90723 Nr4a2 Positive_regulation of Egr1 1 0.22 0.49 0.35
115 INT252453 Binding of AR and Adora2b 1 0.05 0 0.35
116 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
117 INT297352 KLF2 Regulation of PPARA 1 0.12 1.31 0.35
118 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34
119 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
120 INT262218 Nr1h4 Regulation of Nr1i2 1 0.10 0.15 0.34
121 INT297351 EWSR1 Positive_regulation of PPARA 1 0.41 1.81 0.33
122 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33
123 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
124 INT107616 IL1B Positive_regulation of PTGER3 1 0.37 0 0.33
125 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
126 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
127 INT75641 AR Positive_regulation of Positive_regulation of EIF2B3 1 0.02 0 0.33
128 INT253147 Positive_regulation of Nr1h2 Negative_regulation of Positive_regulation of Ptpn1 1 0.17 0.61 0.33
129 INT116292 Gm9662 Negative_regulation of Pparg 1 0.00 0 0.33
130 INT253142 Positive_regulation of Nr1h2 Negative_regulation of Gene_expression of Mmp9 1 0.05 0.6 0.33
131 INT349664 PYCARD Negative_regulation of Localization of AR 1 0.05 0 0.32
132 INT116291 Gm9662 Negative_regulation of Positive_regulation of Pparg 1 0.00 0 0.32
133 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
134 INT349662 Binding of PYCARD and Negative_regulation of Localization of AR 1 0.05 0 0.32
135 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32
136 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
137 INT104932 AHR Positive_regulation of CYP1A1 1 0.43 0.83 0.31
138 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
139 INT332972 Fas Positive_regulation of Ppara 1 0.17 0.52 0.31
140 INT187603 Binding of Ptgis and Ppara 1 0.00 0.26 0.31
141 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
142 INT209931 IL1B Positive_regulation of PPARA 1 0.32 0.62 0.31
143 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
144 INT307215 Negative_regulation of Prkca Negative_regulation of Ppara 1 0.09 0.21 0.3
145 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
146 INT99599 ZNF398 Negative_regulation of NR4A2 1 0.05 0.41 0.3
147 INT99600 ZNF398 Negative_regulation of Transcription of NR4A2 1 0.10 0.41 0.3
148 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
149 INT239344 Nr1h2 Positive_regulation of Gene_expression of Srebf1 1 0.26 0.84 0.29
150 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
151 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
152 INT209933 PPARA Regulation of Positive_regulation of IL1B 1 0.21 0.58 0.29
153 INT239324 Nr1h2 Positive_regulation of Hltf 1 0.04 0.78 0.29
154 INT239347 Nr1h2 Positive_regulation of Srebf1 1 0.26 0.78 0.29
155 INT239329 Nr1h2 Positive_regulation of Gene_expression of Hltf 1 0.04 0.84 0.29
156 INT262208 Clta Positive_regulation of Nr1i2 1 0.09 0.59 0.29
157 INT299956 Binding of PPARA and EPC1 1 0.09 0.34 0.29
158 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
159 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
160 INT266766 Binding of PGR and GOPC 1 0.00 1.08 0.29
161 INT239336 Nr1h2 Positive_regulation of Gene_expression of Fas 1 0.07 0.84 0.29
162 INT335134 PPARA Negative_regulation of Cyp1a1 1 0.47 0 0.28
163 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28
164 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
165 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
166 INT159201 Binding of Ppard and Ppara 1 0.01 0.68 0.28
167 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28
168 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
169 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
170 INT262144 Nr1h4 Positive_regulation of Positive_regulation of Nr1i2 1 0.19 0.19 0.27
171 INT262194 Rhof Positive_regulation of Nr1i2 1 0.15 0.64 0.27
172 INT101510 PPARA Regulation of IL6 1 0.31 0.53 0.27
173 INT262164 Positive_regulation of Rhof Positive_regulation of Nr1i2 1 0.11 0.65 0.27
174 INT96788 Binding of SP3 and NR2F2 1 0.24 0.27 0.27
175 INT101508 PPARA Regulation of IL8 1 0.31 0.53 0.27
176 INT96789 Binding of SP1 and NR2F2 1 0.24 0.27 0.27
177 INT337884 Ins1 Negative_regulation of Gene_expression of Nr2f2 1 0.11 0.08 0.27
178 INT103279 PGR Negative_regulation of Gene_expression of CCL5 1 0.32 0.31 0.27
179 INT101509 PPARA Regulation of Gene_expression of IL8 1 0.31 0.53 0.27
180 INT114230 NR1I2 Positive_regulation of Positive_regulation of CYP2C9 1 0.13 0.61 0.27
181 INT337896 Ins1 Negative_regulation of Nr2f2 1 0.15 0.1 0.27
182 INT101511 PPARA Regulation of Gene_expression of IL6 1 0.31 0.53 0.27
183 INT335130 PPARA Positive_regulation of Cyp8b1 1 0.37 0 0.27
184 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
185 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
186 INT103280 PGR Negative_regulation of Positive_regulation of ATF4 1 0.02 0.31 0.26
187 INT335049 PPARA Negative_regulation of Gene_expression of CYP7B1 1 0.27 0 0.26
188 INT239335 Eef1a2 Positive_regulation of Ppara 1 0.27 0.57 0.26
189 INT110373 CYP4A11 Positive_regulation of PPARG 1 0.00 0.94 0.26
190 INT245072 PPARA Regulation of Gene_expression of CXCR4 1 0.07 0.68 0.26
191 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
192 INT310700 PGR Regulation of Gene_expression of RPLP0 1 0.01 0.37 0.25
193 INT223042 AR Positive_regulation of ADCY1 1 0.01 0.41 0.25
194 INT139357 Nr1h2 Regulation of Gene_expression of Ptges 1 0.07 0.5 0.25
195 INT335126 Ptgs2 Positive_regulation of Gene_expression of PPARA 1 0.24 0.72 0.25
196 INT262202 Nr1i2 Regulation of Abcc2 1 0.19 0.12 0.25
197 INT261375 Binding of Nsdhl and Pparg 1 0.05 1.03 0.25
198 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25
199 INT262200 Nr1i2 Regulation of Sult2a1 1 0.31 0.12 0.25
200 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25

Single Events

The table below shows the top 100 pain related interactions that have been reported for ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity. They are ordered first by their pain relevance and then by number of times they were reported in ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36
2 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14
3 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45
4 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
5 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
6 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61
7 INT122041 Binding of Ppara 308 0.48 189.17 51.48
8 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
9 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
10 INT103094 Binding of PPARA 308 0.47 177.26 34.75
11 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
12 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55
13 INT115385 Negative_regulation of Ppara 154 0.58 129.05 27.58
14 INT37296 Binding of Esr1 117 0.43 62.51 27.33
15 INT5206 Gene_expression of AR 316 0.78 113.83 27.29
16 INT20462 Binding of ESR1 210 0.44 102.7 26.34
17 INT67610 Positive_regulation of Pparg 53 0.70 31.91 25.2
18 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
19 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19
20 INT61116 Positive_regulation of Ppara 119 0.69 58.62 21.6
21 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
22 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41
23 INT85952 Positive_regulation of AR 168 0.67 64.36 20.66
24 INT67608 Gene_expression of Pparg 41 0.78 25.09 19.53
25 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
26 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
27 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98
28 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
29 INT92354 Localization of ESR1 77 0.75 33.04 15.51
30 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
31 INT103096 Regulation of PPARA 113 0.60 62.47 14.57
32 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53
33 INT47708 Gene_expression of Nr4a1 30 0.78 5.12 13.59
34 INT2038 Localization of Esr1 104 0.79 40.12 13.27
35 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23
36 INT122037 Regulation of Ppara 93 0.62 56.28 12.89
37 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79
38 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
39 INT21987 Positive_regulation of Rorb 30 0.33 12.7 12.24
40 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
41 INT194462 Localization of Ppara 94 0.78 68.33 12.09
42 INT79685 Positive_regulation of Gene_expression of Pparg 17 0.70 14.63 11.03
43 INT173159 Localization of PPARA 96 0.74 64.55 10.26
44 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76
45 INT125444 Gene_expression of Rora 5 0.75 3.05 8.97
46 INT67612 Binding of PPARG 38 0.48 22.67 8.94
47 INT35366 Binding of AR 87 0.47 30.52 8.9
48 INT47701 Positive_regulation of Nr4a1 26 0.70 4.45 8.64
49 INT121943 Positive_regulation of Nr1i2 64 0.68 19.22 8.39
50 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
51 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73
52 INT181817 Negative_regulation of Gene_expression of Ppara 58 0.58 43.24 7.67
53 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47
54 INT103399 Positive_regulation of Positive_regulation of Pparg 11 0.66 7 7.36
55 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
56 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89
57 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
58 INT170922 Binding of Ppara 59 0.45 28.45 6.7
59 INT61114 Gene_expression of Ppard 23 0.75 14.98 6.62
60 INT50387 Negative_regulation of AR 67 0.45 26.31 6.61
61 INT194479 Phosphorylation of Ppara 47 0.81 30.36 6.6
62 INT96218 Positive_regulation of Pgr 17 0.68 5.23 6.57
63 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
64 INT116617 Phosphorylation of Rorb 15 0.07 3.43 6.12
65 INT67609 Binding of Pparg 17 0.46 9.53 6.06
66 INT129901 Gene_expression of Nr1i2 60 0.73 22.44 6.04
67 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96
68 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
69 INT86025 Positive_regulation of Positive_regulation of PPARA 34 0.52 22.89 5.74
70 INT86023 Transcription of PPARA 60 0.66 25.8 5.7
71 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
72 INT107619 Gene_expression of PTGER3 42 0.75 15 5.61
73 INT91147 Positive_regulation of Positive_regulation of Ppara 30 0.69 19.31 5.56
74 INT90752 Positive_regulation of Gene_expression of Nr4a1 13 0.70 2.83 5.53
75 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
76 INT58489 Gene_expression of Rorb 51 0.41 4.7 5.39
77 INT122038 Transcription of Ppara 35 0.71 20.5 5.12
78 INT170927 Negative_regulation of Ppara 27 0.54 13.58 5.12
79 INT99091 Regulation of AR 70 0.45 31.68 5.05
80 INT25831 Gene_expression of NR4A2 20 0.74 2.73 4.92
81 INT181186 Binding of Rxra 78 0.35 14.93 4.87
82 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
83 INT4577 Negative_regulation of Thra 24 0.56 3.75 4.73
84 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67
85 INT186421 Positive_regulation of Phosphorylation of Rorb 9 0.06 1.26 4.65
86 INT5205 Localization of AR 43 0.80 12.87 4.63
87 INT84727 Negative_regulation of Gene_expression of AR 38 0.58 12.46 4.63
88 INT337882 Gene_expression of Nr2f2 1 0.76 3.45 4.6
89 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
90 INT197171 Negative_regulation of Binding of Ppara 15 0.43 11.51 4.41
91 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
92 INT88947 Positive_regulation of Gene_expression of Pgr 22 0.64 7 4.39
93 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
94 INT89925 Gene_expression of NR1I2 22 0.75 9.63 4.21
95 INT14165 Negative_regulation of Ahr 14 0.51 8.35 4.17
96 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
97 INT72936 Gene_expression of Pparg 39 0.77 19.01 4.02
98 INT112070 Negative_regulation of Gene_expression of Pparg 6 0.59 3.72 3.96
99 INT47705 Regulation of Nr4a1 10 0.62 0.84 3.9
100 INT39691 Positive_regulation of NR1I3 2 0.59 1.46 3.88
101 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84
102 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
103 INT20461 Binding of Esr1 34 0.48 9.58 3.66
104 INT121942 Binding of Nr1i2 2 0.45 15.69 3.66
105 INT114957 Positive_regulation of Transcription of PPARA 18 0.62 10.36 3.65
106 INT84891 Gene_expression of PPARD 10 0.78 6.8 3.64
107 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53
108 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53
109 INT78845 Binding of Pparg 16 0.44 11.67 3.53
110 INT91929 Gene_expression of Nr5a2 5 0.31 2.15 3.52
111 INT86977 Positive_regulation of Nr4a3 7 0.10 0.73 3.5
112 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
113 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33
114 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28
115 INT147522 Positive_regulation of Gene_expression of Ppara 28 0.47 15.82 3.18
116 INT101959 Regulation of Rorb 10 0.14 5.18 3.17
117 INT102034 Positive_regulation of Ppard 10 0.69 3.97 3.17
118 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15
119 INT114276 Gene_expression of Nr4a1 20 0.77 7.71 3.14
120 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
121 INT107011 Positive_regulation of NR1I2 14 0.49 8.85 3.11
122 INT110956 Negative_regulation of Positive_regulation of Pparg 5 0.41 3.68 3.11
123 INT84890 Negative_regulation of PPARD 7 0.59 3.27 3.1
124 INT187618 Localization of Ppara 13 0.70 6.91 3.09
125 INT112071 Regulation of Gene_expression of Pparg 4 0.62 4.62 3.09
126 INT82913 Regulation of Ppara 15 0.61 10.66 3.03
127 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02
128 INT2897 Positive_regulation of Thra 20 0.45 5.17 3.01
129 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99
130 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
131 INT136982 Positive_regulation of Positive_regulation of Nr1i2 3 0.65 4.66 2.89
132 INT112758 Binding of Ppard 7 0.37 3.6 2.87
133 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85
134 INT132575 Binding of NR1H4 57 0.20 22.06 2.82
135 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
136 INT44661 Regulation of Ahr 15 0.45 12.69 2.79
137 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73
138 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72
139 INT190881 Positive_regulation of Rora 2 0.43 1.76 2.71
140 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
141 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68
142 INT60750 Gene_expression of HNF4A 12 0.65 8.29 2.68
143 INT136105 Regulation of Pgr 4 0.45 1.93 2.62
144 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58
145 INT86980 Transcription of Nr4a3 4 0.45 0.24 2.58
146 INT147517 Negative_regulation of Gene_expression of Ppara 12 0.37 3.46 2.55
147 INT125442 Negative_regulation of Gene_expression of Rora 5 0.57 2.92 2.54
148 INT185927 Positive_regulation of Positive_regulation of AR 12 0.34 6.35 2.5
149 INT102033 Negative_regulation of Ppard 5 0.37 4.14 2.48
150 INT50723 Positive_regulation of Nr4a2 7 0.53 0.47 2.46
151 INT197228 Positive_regulation of Gene_expression of Rora 1 0.05 0 2.43
152 INT99607 Transcription of NR4A2 2 0.68 1.61 2.41
153 INT96876 Gene_expression of AHR 20 0.77 10.43 2.39
154 INT90314 Regulation of Gene_expression of Nr4a1 2 0.61 0.23 2.37
155 INT215379 Positive_regulation of Binding of Ppara 15 0.66 8.04 2.36
156 INT108796 Binding of ESR2 5 0.46 6.84 2.36
157 INT34830 Regulation of PGR 14 0.45 6.99 2.32
158 INT129902 Regulation of Nr1i2 16 0.58 6.3 2.31
159 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3
160 INT22605 Regulation of Pgr 22 0.62 7.1 2.26
161 INT178632 Regulation of Gene_expression of Pgr 11 0.35 1.56 2.26
162 INT47700 Transcription of Nr4a1 9 0.69 1.37 2.25
163 INT83236 Localization of PGR 14 0.73 8.26 2.23
164 INT13267 Binding of Pgr 15 0.40 3.5 2.22
165 INT81294 Negative_regulation of Positive_regulation of Pparg 7 0.58 4.39 2.2
166 INT101516 Positive_regulation of PPARD 8 0.49 4.75 2.19
167 INT78844 Regulation of Pparg 6 0.41 4 2.19
168 INT215378 Protein_catabolism of Ppara 12 0.86 5.12 2.14
169 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12
170 INT68496 Binding of PGR 26 0.48 16.36 2.09
171 INT337864 Positive_regulation of Gene_expression of Nr2f2 1 0.68 0.48 2.07
172 INT114953 Gene_expression of NR1H4 23 0.29 16.58 2.02
173 INT130082 Regulation of Rxra 6 0.42 3.78 1.96
174 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
175 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
176 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89
177 INT176173 Positive_regulation of Nr1h2 19 0.52 10.95 1.88
178 INT173180 Positive_regulation of Binding of PPARA 14 0.49 3.66 1.88
179 INT199724 Positive_regulation of Gene_expression of Rxra 11 0.45 6.22 1.88
180 INT211984 Regulation of Binding of Ppara 11 0.45 9.55 1.87
181 INT168269 Negative_regulation of Positive_regulation of Ppara 3 0.38 0.57 1.87
182 INT96877 Transcription of AHR 7 0.62 3.25 1.77
183 INT134197 Regulation of AHR 11 0.44 4.82 1.76
184 INT173177 Positive_regulation of Localization of PPARA 21 0.49 12.61 1.74
185 INT96216 Negative_regulation of Positive_regulation of Pgr 2 0.37 0.74 1.72
186 INT14167 Negative_regulation of Positive_regulation of Ahr 5 0.51 1.54 1.71
187 INT81169 Localization of Nr4a2 1 0.68 0 1.71
188 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69
189 INT90751 Negative_regulation of Gene_expression of Nr4a1 3 0.59 0.75 1.69
190 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
191 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
192 INT117438 Positive_regulation of Gene_expression of Pparg 11 0.69 8 1.63
193 INT58488 Positive_regulation of Gene_expression of Rorb 7 0.19 1.98 1.63
194 INT110906 Binding of Rorb 14 0.48 2.88 1.62
195 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62
196 INT200369 Negative_regulation of Rorb 6 0.07 3.76 1.62
197 INT10598 Gene_expression of Ar 10 0.64 3.44 1.61
198 INT145318 Transcription of Rorb 8 0.37 0.77 1.61
199 INT95056 Positive_regulation of Gene_expression of Ppard 5 0.52 3.84 1.6
200 INT15969 Negative_regulation of Ar 11 0.43 2.77 1.59
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