GO:0004886

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Name 9-cis retinoic acid receptor activity
Categary Function
Go Slim No
Go Link GO:0004886
Unique Molecular Interactions 61
Total Molecular Interactions 94
Total Single Events 354
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for 9-cis retinoic acid receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for 9-cis retinoic acid receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11
2 INT128859 Positive_regulation of RXRA Regulation of Gene_expression of OPRM1 1 0.05 0.26 0.9
3 INT114947 YY1 Positive_regulation of Gene_expression of RXRA 1 0.33 0.25 0.65
4 INT114951 PPARA Positive_regulation of Gene_expression of RXRA 1 0.34 0.25 0.64
5 INT114949 NCOA1 Positive_regulation of Gene_expression of RXRA 1 0.13 0.24 0.61
6 INT333453 Binding of PPARA and RXRA 1 0.02 0 0.31
7 INT108841 RXRG Positive_regulation of GDF15 1 0.41 0.58 0.24
8 INT297376 Binding of RARS and Rxra 1 0.01 3.27 0.24
9 INT312550 DAK Positive_regulation of Rxra 1 0.00 1.48 0.18
10 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
11 INT333447 Binding of SMAD2 and RXRA 1 0.04 0 0.16
12 INT192103 Binding of Rxrg and Retsat 1 0.01 0.83 0.13
13 INT192102 Regulation of Binding of Rxrg and Retsat 1 0.01 0.83 0.13
14 INT192101 Binding of Rxrg and Regulation of Retsat 1 0.00 0.83 0.13
15 INT264391 RXRG Negative_regulation of IL1R2 1 0.02 0.09 0.12
16 INT290563 Binding of Rxrg and Rorb 1 0.00 0.2 0.12
17 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1
18 INT166723 Binding of Vdr and Rxrb 1 0.11 0.31 0.09
19 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09
20 INT248704 Trib3 Positive_regulation of Phosphorylation of Rxrb 1 0.00 0.49 0.08
21 INT229703 Binding of Ppara and Rxrg 1 0.03 0.08 0.08
22 INT278684 Binding of NR1I3 and Rxra 1 0.00 0 0.07
23 INT236932 Binding of Rxra and Pprc1 1 0.00 0.45 0.07
24 INT278685 Binding of CASR and Rxra 1 0.00 0 0.07
25 INT285384 Binding of Rare1 and Rxra 1 0.01 0.08 0.05
26 INT187602 Binding of Ppara and Rxrb 1 0.00 0 0.05
27 INT307218 Binding of Rxra and D0Nrs1 1 0.00 0.1 0.05
28 INT248703 Mapk8 Positive_regulation of Phosphorylation of Rxrb 1 0.01 0.25 0.04
29 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
30 INT206898 Binding of PPARA and Rxrg 1 0.00 1.36 0.03
31 INT248700 Binding of Nr0b2 and Rxrb 1 0.01 0.29 0.03
32 INT297377 Binding of PPARA and Rxra 1 0.02 0.25 0.03
33 INT297375 Binding of VDR and Rxra 1 0.02 0.2 0.03
34 INT297374 Binding of TXNRD1 and Rxra 1 0.01 0.2 0.03
35 INT291715 Binding of DR1 and Rxra 1 0.09 0 0
36 INT290024 Binding of PPARG and RXRG 1 0.15 0.39 0
37 INT291716 Binding of SOD1 and Rxra 1 0.21 0 0
38 INT236719 Binding of Dr1 and Rxra 1 0.01 0 0
39 INT290023 Binding of PPARD and RXRG 1 0.03 0.39 0
40 INT239239 Binding of PPARA and RXRB 1 0.12 0.63 0
41 INT330959 Binding of RXRB and VDR 1 0.05 0.14 0
42 INT291712 Binding of Rxra and SPNS1 1 0.04 0 0
43 INT248705 Binding of Nr1i2 and Rxrb 1 0.01 0.18 0
44 INT290032 Binding of INS and RXRG 1 0.03 0.47 0
45 INT135127 Binding of RXRB and NR1I2 1 0.29 0.57 0
46 INT291711 Rxra Positive_regulation of VDR 1 0.09 0 0
47 INT291713 Binding of TNFRSF10B and Rxra 1 0.05 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for 9-cis retinoic acid receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in 9-cis retinoic acid receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114274 Gene_expression of Rxra 67 0.70 36.77 12.5
2 INT181186 Binding of Rxra 78 0.35 14.93 4.87
3 INT130080 Negative_regulation of Rxra 6 0.53 2.08 2.92
4 INT169318 Positive_regulation of Rxra 15 0.42 4.35 2.12
5 INT130082 Regulation of Rxra 6 0.42 3.78 1.96
6 INT199724 Positive_regulation of Gene_expression of Rxra 11 0.45 6.22 1.88
7 INT128865 Regulation of Positive_regulation of RXRA 1 0.08 0.64 1.48
8 INT128863 Positive_regulation of RXRA 1 0.12 0.63 1.47
9 INT187617 Binding of Rxrb 7 0.06 4.86 1.37
10 INT132577 Binding of RXRB 12 0.30 6.58 1.25
11 INT166720 Positive_regulation of Rxrb 2 0.36 0.84 1.13
12 INT220433 Gene_expression of RXRB 3 0.14 1.83 0.63
13 INT114959 Gene_expression of RXRA 2 0.50 1.06 0.63
14 INT114960 Positive_regulation of Gene_expression of RXRA 1 0.32 0.24 0.61
15 INT199723 Localization of Rxra 8 0.59 1.31 0.58
16 INT248682 Gene_expression of Rxrb 8 0.60 1.41 0.58
17 INT114277 Regulation of Gene_expression of Rxra 1 0.28 0.75 0.58
18 INT192094 Binding of Rxrg 5 0.05 4.38 0.52
19 INT265656 Positive_regulation of Gene_expression of RXRB 1 0.04 0.24 0.5
20 INT264451 Binding of RXRG 1 0.09 1.14 0.45
21 INT264487 Regulation of Positive_regulation of Rxrb 1 0.21 0.36 0.4
22 INT285391 Binding of RXRA 2 0.03 0.08 0.36
23 INT199725 Negative_regulation of Gene_expression of Rxra 2 0.38 0.3 0.3
24 INT236564 Positive_regulation of Binding of Rxra 2 0.18 1.3 0.24
25 INT229696 Gene_expression of Rxrg 3 0.07 0.26 0.2
26 INT206946 Gene_expression of Rxra 4 0.60 2.2 0.17
27 INT332915 Positive_regulation of Localization of Rxra 1 0.03 0.3 0.11
28 INT214072 Regulation of Gene_expression of RXRA 1 0.01 0.83 0.09
29 INT166719 Positive_regulation of Rxra 1 0.36 0.31 0.09
30 INT229700 Positive_regulation of Binding of Rxrg 1 0.05 0.08 0.08
31 INT264489 Transcription of Rxrb 1 0.53 0.09 0.07
32 INT220435 Regulation of Gene_expression of RXRB 1 0.01 0.25 0.06
33 INT256518 Positive_regulation of Transcription of Rxra 1 0.04 0.24 0.06
34 INT234452 Phosphorylation of RXRB 1 0.29 0.66 0.06
35 INT220430 Negative_regulation of Gene_expression of RXRB 1 0.02 0.25 0.06
36 INT291692 Regulation of Binding of Rxra 4 0.32 0.57 0.05
37 INT248665 Phosphorylation of Rxrb 1 0.07 0.42 0.04
38 INT248680 Positive_regulation of Phosphorylation of Rxrb 1 0.05 0.24 0.04
39 INT225406 Transcription of Rxra 3 0.41 0.33 0.03
40 INT248671 Regulation of Rxrb 1 0.02 0.86 0.03
41 INT256507 Regulation of Transcription of Rxra 1 0.04 0.12 0.03
42 INT206893 Regulation of Rxrg 1 0.01 1.31 0.03
43 INT291693 Negative_regulation of Binding of Rxra 1 0.22 0.07 0.03
44 INT248676 Positive_regulation of Gene_expression of Rxrb 1 0.05 0.18 0
45 INT231922 Negative_regulation of Positive_regulation of Rxra 1 0.06 0.33 0
46 INT90889 Positive_regulation of Rxrg 1 0.11 0.95 0
47 INT346487 Negative_regulation of Phosphorylation of RXRA 1 0.01 0.63 0
48 INT291694 Negative_regulation of Localization of Rxra 1 0.22 0 0
49 INT248686 Regulation of Gene_expression of Rxrb 1 0.04 0.23 0
50 INT291695 Regulation of Negative_regulation of Rxra 1 0.23 0.14 0
51 INT346494 Phosphorylation of RXRA 1 0.01 0.63 0
52 INT291698 Negative_regulation of Negative_regulation of Rxra 1 0.22 0 0
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