GO:0004909

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Name interleukin-1, Type I, activating receptor activity
Categary Function
Go Slim No
Go Link GO:0004909
Unique Molecular Interactions 16
Total Molecular Interactions 26
Total Single Events 109
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-1, Type I, activating receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-1, Type I, activating receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64
2 INT229094 Binding of IL1RN and Il1r1 1 0.01 1.9 1.5
3 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
4 INT281375 Il1r1 Negative_regulation of Gene_expression of Fos 1 0.47 0.61 0.97
5 INT229085 IL1RN Negative_regulation of Positive_regulation of IL1R1 1 0.12 1.72 0.68
6 INT85487 IL1RN Negative_regulation of IL1R1 1 0.02 0 0.57
7 INT229095 Binding of IL1R1 and Il1r1 1 0.00 0.64 0.5
8 INT307675 Binding of IL1R1 and SNRNP70 1 0.02 1.05 0.45
9 INT229087 IL1R1 Negative_regulation of ACCS 1 0.03 0.86 0.33
10 INT195114 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of F2r 1 0.38 1.67 0.18
11 INT229088 IL1R1 Positive_regulation of Gene_expression of IL6 1 0.04 0.45 0.14
12 INT229089 IL1R1 Positive_regulation of IL6 1 0.03 0.45 0.12
13 INT300545 Il6 Positive_regulation of Gene_expression of Il1r1 1 0.02 0.42 0.11
14 INT195121 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of Gopc 1 0.17 0.26 0.11
15 INT195119 Gene_expression of Il1r1 Positive_regulation of Positive_regulation of Gfap 1 0.38 0.26 0.11

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-1, Type I, activating receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-1, Type I, activating receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT36030 Gene_expression of Il1r1 16 0.68 11.42 4.87
2 INT181596 Binding of IL1R1 9 0.36 7.99 4.32
3 INT64437 Gene_expression of IL1R1 9 0.65 6.22 2.99
4 INT126966 Positive_regulation of IL1R1 8 0.67 6.93 2.84
5 INT36029 Negative_regulation of Il1r1 9 0.41 4.64 2.3
6 INT67895 Negative_regulation of IL1R1 7 0.57 5.76 1.9
7 INT124559 Gene_expression of Il1r1 4 0.54 2.14 1.89
8 INT85492 Localization of IL1R1 6 0.72 2.44 1.85
9 INT52873 Localization of Il1r1 4 0.56 1.28 1.48
10 INT124560 Negative_regulation of Il1r1 2 0.07 0.77 1.14
11 INT98489 Binding of Il1r1 3 0.36 1.46 1.06
12 INT36028 Positive_regulation of Gene_expression of Il1r1 4 0.40 1.82 0.81
13 INT151626 Negative_regulation of Gene_expression of Il1r1 1 0.20 1.33 0.8
14 INT112947 Regulation of Il1r1 2 0.24 0.36 0.78
15 INT112945 Transcription of Il1r1 1 0.39 0.32 0.76
16 INT195104 Positive_regulation of Il1r1 4 0.40 2.18 0.68
17 INT64438 Regulation of IL1R1 2 0.26 1.62 0.64
18 INT67894 Transcription of IL1R1 4 0.67 2.17 0.45
19 INT201841 Negative_regulation of Negative_regulation of IL1R1 1 0.01 0.78 0.34
20 INT229092 Positive_regulation of Localization of IL1R1 1 0.14 0.41 0.34
21 INT124558 Regulation of Gene_expression of Il1r1 1 0.07 0.29 0.28
22 INT201860 Negative_regulation of Transcription of IL1R1 1 0.01 0.85 0.26
23 INT230491 Regulation of Il1r1 1 0.01 0.76 0.25
24 INT229093 Negative_regulation of Localization of IL1R1 1 0.12 0.39 0.15
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