GO:0004921

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Name interleukin-11 receptor activity
Categary Function
Go Slim No
Go Link GO:0004921
Unique Molecular Interactions 15
Total Molecular Interactions 22
Total Single Events 83
Pain Genes Associated 2

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for interleukin-11 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for interleukin-11 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22
2 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1
3 INT286798 Binding of Il6st and Cntf 1 0.10 1.34 0.97
4 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4
5 INT184135 Il11ra1 Positive_regulation of Stat3 1 0.20 0.3 0.4
6 INT184092 Il11ra1 Positive_regulation of Jak1 1 0.17 0.3 0.39
7 INT328821 Binding of Il6st and Jak1 1 0.05 0 0.38
8 INT328827 Binding of Jak2 and Il6st 1 0.05 0 0.38
9 INT328824 Binding of Il6st and TYK2 1 0.02 0 0.38
10 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33
11 INT316491 Socs3 Positive_regulation of Il11ra1 1 0.45 0.92 0.22
12 INT184103 Binding of Socs3 and Il11ra1 1 0.12 0 0.17
13 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08
14 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08
15 INT289244 Binding of Il11ra1 and Il6ra 1 0.01 0.33 0.07

Single Events

The table below shows the top 100 pain related interactions that have been reported for interleukin-11 receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in interleukin-11 receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT163913 Gene_expression of Il11ra1 18 0.69 12.62 5.34
2 INT89986 Gene_expression of Il6st 5 0.56 2.35 3.15
3 INT163911 Negative_regulation of Il11ra1 4 0.39 6.43 2.73
4 INT89250 Positive_regulation of Il11ra1 8 0.63 3.99 2.27
5 INT163912 Binding of Il11ra1 5 0.33 5.06 2.22
6 INT253403 Positive_regulation of Il6st 2 0.28 2.07 1.54
7 INT159009 Regulation of Il6st 2 0.18 2 1.41
8 INT163915 Positive_regulation of Gene_expression of Il11ra1 2 0.41 1.84 1.37
9 INT163910 Negative_regulation of Gene_expression of Il11ra1 3 0.39 2.11 1.08
10 INT184053 Regulation of Il11ra1 3 0.16 2.03 0.68
11 INT333965 Binding of Il6st 1 0.08 0.9 0.65
12 INT179795 Transcription of Il11ra1 1 0.50 0 0.36
13 INT176612 Localization of Il11ra1 2 0.71 0.86 0.33
14 INT176611 Negative_regulation of Localization of Il11ra1 1 0.03 0.89 0.33
15 INT176610 Positive_regulation of Localization of Il11ra1 1 0.03 0.86 0.33
16 INT126195 Transcription of Il6st 1 0.39 0.2 0.28
17 INT269045 Positive_regulation of Binding of Il11ra1 1 0.19 0.72 0.22
18 INT316435 Positive_regulation of Positive_regulation of Il11ra1 1 0.46 0.29 0.15
19 INT299517 Positive_regulation of Gene_expression of Il6st 1 0.06 0.23 0.09
20 INT316446 Phosphorylation of Il11ra1 1 0.57 0.44 0.09
21 INT253389 Positive_regulation of Positive_regulation of Il6st 1 0.28 0.07 0.05
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