GO:0004947

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Name bradykinin receptor activity
Categary Function
Go Slim No
Go Link GO:0004947
Unique Molecular Interactions 79
Total Molecular Interactions 83
Total Single Events 1211
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for bradykinin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for bradykinin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT324927 Syt17 Positive_regulation of Bdkrb1 1 0.04 4.29 2.96
2 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
3 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
4 INT324926 Ptpro Positive_regulation of Bdkrb2 1 0.01 2.25 1.5
5 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3
6 INT299985 BDKRB2 Regulation of Gene_expression of BDKRB1 1 0.21 0.75 1.16
7 INT299986 BDKRB2 Regulation of Gene_expression of SPANXB1 1 0.29 0.51 1.02
8 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
9 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
10 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
11 INT127240 Bdkrb1 Regulation of Ssr1 1 0.01 0.08 0.84
12 INT299990 BDKRB2 Positive_regulation of TRPV1 1 0.43 0.74 0.84
13 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81
14 INT150643 Binding of Bdkrb2 and Trpa1 1 0.36 0.55 0.78
15 INT140790 Positive_regulation of Ptger3 Negative_regulation of Negative_regulation of Bdkrb2 1 0.00 0.07 0.76
16 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
17 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
18 INT324925 Ros1 Positive_regulation of Bdkrb1 1 0.08 0.67 0.6
19 INT121453 Bdkrb2 Positive_regulation of Trpv1 1 0.28 0.42 0.6
20 INT120349 Binding of BDKRB1 and DES 1 0.05 0.17 0.58
21 INT254637 Bdkrb2 Regulation of Gene_expression of Ccl5 1 0.17 1.22 0.56
22 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
23 INT303721 KNG1 Positive_regulation of Bdkrb1 1 0.05 0.75 0.52
24 INT303722 KNG1 Positive_regulation of Bdkrb2 1 0.01 0.7 0.52
25 INT303720 Prkaca Regulation of Bdkrb1 1 0.02 0.33 0.52
26 INT254638 Bdkrb2 Positive_regulation of Positive_regulation of Bdkrb1 1 0.09 0.96 0.48
27 INT80116 Binding of C4orf6 and Bdkrb2 1 0.41 0.18 0.47
28 INT261648 BDKRB1 Regulation of PRKCA 1 0.03 1.9 0.47
29 INT242401 Negative_regulation of Bdkrb1 Negative_regulation of Gene_expression of Mcpt1 1 0.16 1.45 0.46
30 INT242402 Negative_regulation of Bdkrb1 Positive_regulation of Hmox1 1 0.17 1.44 0.45
31 INT165724 Bdkrb1 Positive_regulation of Adora1 1 0.24 1.65 0.43
32 INT254636 Bdkrb2 Regulation of Gene_expression of Ccl2 1 0.15 1.15 0.43
33 INT85511 Binding of KNG1 and Bdkrb2 1 0.54 0.51 0.4
34 INT332701 Binding of BDKRB1 and BDKRB2 1 0.01 0.5 0.39
35 INT330120 Bdkrb2 Regulation of Bdkrb1 1 0.19 1.26 0.38
36 INT242403 INSR Positive_regulation of Gene_expression of Bdkrb1 1 0.45 0.88 0.35
37 INT136008 Binding of BDKRB2 and INSRR 1 0.01 0.17 0.34
38 INT330121 Agtr1a Positive_regulation of Gene_expression of Bdkrb1 1 0.05 0.68 0.34
39 INT330119 Agt Positive_regulation of Gene_expression of Bdkrb1 1 0.37 0.63 0.34
40 INT337327 KNG1 Positive_regulation of BDKRB2 1 0.21 0.4 0.32
41 INT281903 BDKRB1 Positive_regulation of KNG1 1 0.03 0.32 0.21
42 INT269333 Binding of BDKRB2 and NOS3 1 0.02 0 0.17
43 INT242400 Binding of Bdkrb2 and Ros1 1 0.02 0.84 0.15
44 INT336990 Binding of AGTR1 and BDKRB2 1 0.03 0 0.1
45 INT281906 BDKRB2 Positive_regulation of ANG 1 0.11 0.51 0.05
46 INT261647 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of BDKRB1 1 0.04 0.6 0.04
47 INT261649 Positive_regulation of PRKCA Positive_regulation of BDKRB1 1 0.04 0.59 0.04
48 INT316217 BDKRB1 Positive_regulation of BDKRB2 1 0.09 0.71 0.03
49 INT316218 GOPC Positive_regulation of BDKRB2 1 0.08 0.71 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for bradykinin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in bradykinin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20266 Positive_regulation of Bdkrb1 60 0.69 63.64 56.59
2 INT49643 Gene_expression of Bdkrb1 39 0.78 46.49 40.21
3 INT28834 Positive_regulation of Bdkrb1 38 0.69 30.48 26.89
4 INT6848 Gene_expression of BDKRB2 40 0.75 17.19 20.04
5 INT67975 Gene_expression of Bdkrb2 38 0.68 21.69 17.94
6 INT30517 Negative_regulation of Bdkrb1 16 0.58 16.52 16.88
7 INT3926 Regulation of Bdkrb1 22 0.61 16.72 16.1
8 INT59987 Gene_expression of BDKRB1 25 0.77 11.95 15.93
9 INT78827 Gene_expression of Bdkrb1 34 0.78 18.48 15.81
10 INT61301 Positive_regulation of Gene_expression of Bdkrb1 7 0.68 16.95 15.44
11 INT37803 Positive_regulation of Bdkrb2 18 0.68 14.21 13.99
12 INT6645 Positive_regulation of BDKRB1 14 0.66 12.17 13.79
13 INT85510 Positive_regulation of Bdkrb2 23 0.70 12.08 12.68
14 INT66718 Positive_regulation of BDKRB2 21 0.64 9.89 11.6
15 INT88223 Gene_expression of Bdkrb2 17 0.69 13.94 11.44
16 INT7104 Binding of Bdkrb1 6 0.37 6.54 9.02
17 INT9573 Regulation of Bdkrb2 9 0.43 6.04 8.41
18 INT113038 Positive_regulation of Gene_expression of Bdkrb1 12 0.69 7.11 7.93
19 INT3928 Localization of Bdkrb1 15 0.75 4.06 7.23
20 INT98260 Negative_regulation of Gene_expression of Bdkrb1 4 0.57 5.98 6.7
21 INT70139 Regulation of Bdkrb1 6 0.52 8.41 6.66
22 INT65772 Positive_regulation of Positive_regulation of Bdkrb1 6 0.49 8.34 6.54
23 INT65295 Negative_regulation of Bdkrb2 9 0.37 6.36 6.49
24 INT52464 Negative_regulation of Bdkrb1 9 0.57 8.71 5.87
25 INT83095 Regulation of Gene_expression of BDKRB2 2 0.59 4.06 5.39
26 INT125396 Positive_regulation of Positive_regulation of Bdkrb1 5 0.69 5.14 5.2
27 INT59983 Regulation of BDKRB1 12 0.45 10.69 5.11
28 INT48277 Regulation of BDKRB2 9 0.59 2.69 5.05
29 INT113037 Transcription of Bdkrb1 4 0.69 3.89 4.82
30 INT70137 Regulation of Bdkrb2 10 0.27 5.45 4.62
31 INT113039 Binding of Bdkrb1 9 0.48 5.71 4.51
32 INT103037 Transcription of Bdkrb1 8 0.70 4.76 4.33
33 INT88221 Positive_regulation of Gene_expression of Bdkrb2 5 0.36 3.35 3.91
34 INT133788 Negative_regulation of Gene_expression of Bdkrb1 7 0.58 3.49 3.75
35 INT61300 Negative_regulation of Binding of Bdkrb1 3 0.42 3 3.69
36 INT76229 Binding of BDKRB1 5 0.33 1.46 3.66
37 INT114750 Negative_regulation of Gene_expression of Bdkrb2 4 0.17 2.68 3.64
38 INT128679 Negative_regulation of Bdkrb2 7 0.35 6.78 3.54
39 INT59984 Regulation of Gene_expression of BDKRB1 2 0.45 2.08 3.47
40 INT59986 Localization of BDKRB1 5 0.61 1.69 3.45
41 INT53347 Localization of BDKRB2 5 0.75 4.96 3.39
42 INT88220 Transcription of Bdkrb2 6 0.65 3.08 3.21
43 INT66720 Negative_regulation of BDKRB2 5 0.57 1.92 3.11
44 INT53348 Binding of BDKRB2 7 0.37 2.85 3
45 INT66716 Negative_regulation of BDKRB1 4 0.48 1.31 3
46 INT126636 Binding of Bdkrb2 3 0.33 2.18 2.78
47 INT88222 Positive_regulation of Transcription of Bdkrb2 3 0.47 1.32 2.51
48 INT303703 Positive_regulation of Transcription of Bdkrb1 2 0.21 2.91 2.41
49 INT133789 Regulation of Gene_expression of Bdkrb1 5 0.39 3 2.38
50 INT28833 Localization of Bdkrb1 3 0.81 2.17 2.28
51 INT28832 Negative_regulation of Positive_regulation of Bdkrb1 3 0.23 1.36 2.04
52 INT62556 Positive_regulation of Gene_expression of BDKRB1 3 0.46 0.65 1.98
53 INT148917 Positive_regulation of Transcription of Bdkrb1 4 0.50 0.88 1.83
54 INT330131 Negative_regulation of Positive_regulation of Bdkrb1 1 0.42 3.52 1.77
55 INT98261 Regulation of Gene_expression of Bdkrb1 3 0.45 1.17 1.68
56 INT131408 Positive_regulation of Negative_regulation of Bdkrb1 1 0.49 1.7 1.32
57 INT133958 Localization of Bdkrb2 2 0.79 0.65 1.29
58 INT120406 Positive_regulation of Positive_regulation of BDKRB2 2 0.27 1.48 1.28
59 INT170031 Positive_regulation of Positive_regulation of Bdkrb2 1 0.09 0.94 1.27
60 INT254634 Positive_regulation of Positive_regulation of Bdkrb2 2 0.32 1.64 1.13
61 INT67974 Positive_regulation of Gene_expression of Bdkrb2 3 0.37 1.13 1.12
62 INT242390 Regulation of Gene_expression of Bdkrb2 3 0.31 1.37 1.06
63 INT120265 Positive_regulation of Binding of BDKRB1 1 0.44 0.64 1.04
64 INT3927 Negative_regulation of Localization of Bdkrb1 2 0.42 0.31 1.02
65 INT66719 Transcription of BDKRB1 2 0.27 0.89 1.01
66 INT37802 Regulation of Positive_regulation of Bdkrb2 1 0.23 0.17 1.01
67 INT111048 Binding of Bdkrb2 2 0.47 2.54 1
68 INT58291 Protein_catabolism of Bdkrb2 3 0.08 1.19 0.94
69 INT58292 Negative_regulation of Protein_catabolism of Bdkrb2 1 0.04 0.82 0.94
70 INT66717 Positive_regulation of Transcription of BDKRB1 1 0.19 0.26 0.93
71 INT300007 Positive_regulation of Positive_regulation of BDKRB1 1 0.48 0.9 0.92
72 INT261686 Phosphorylation of BDKRB1 1 0.13 6.07 0.92
73 INT65294 Negative_regulation of Localization of BDKRB1 1 0.05 0 0.91
74 INT303706 Regulation of Positive_regulation of Bdkrb1 2 0.19 0.64 0.85
75 INT83099 Negative_regulation of Positive_regulation of BDKRB1 1 0.50 0.22 0.83
76 INT83096 Regulation of Positive_regulation of BDKRB1 1 0.45 0.28 0.78
77 INT290271 Negative_regulation of Binding of BDKRB2 1 0.37 0.99 0.76
78 INT254632 Transcription of Bdkrb2 1 0.36 0.54 0.75
79 INT330129 Regulation of Positive_regulation of Bdkrb1 1 0.44 1.26 0.73
80 INT271462 Protein_catabolism of Bdkrb2 1 0.58 0.71 0.72
81 INT169122 Regulation of Transcription of Bdkrb1 2 0.60 0.77 0.69
82 INT143814 Regulation of Localization of Bdkrb2 1 0.16 0.38 0.69
83 INT120352 Positive_regulation of Localization of BDKRB1 1 0.40 0.11 0.68
84 INT133957 Positive_regulation of Localization of Bdkrb2 1 0.46 0.28 0.63
85 INT324924 Positive_regulation of Binding of Bdkrb1 1 0.45 0.82 0.62
86 INT49236 Localization of Bdkrb2 4 0.52 1.6 0.56
87 INT143813 Regulation of Negative_regulation of Bdkrb2 1 0.16 0.14 0.55
88 INT132827 Negative_regulation of Protein_catabolism of BDKRB1 1 0.41 0.15 0.42
89 INT303707 Negative_regulation of Transcription of Bdkrb1 1 0.16 0.31 0.42
90 INT132826 Protein_catabolism of BDKRB1 1 0.63 0.15 0.42
91 INT271458 Regulation of Regulation of Bdkrb2 1 0.40 0.36 0.39
92 INT303708 Positive_regulation of Regulation of Bdkrb1 1 0.20 0.07 0.37
93 INT28831 Positive_regulation of Localization of Bdkrb1 1 0.27 0.17 0.35
94 INT13442 Positive_regulation of Localization of Bdkrb1 1 0.06 0.58 0.3
95 INT59985 Regulation of Localization of BDKRB1 1 0.00 0.21 0.3
96 INT44308 Regulation of Localization of Bdkrb1 1 0.02 0 0.29
97 INT316230 Negative_regulation of Localization of BDKRB2 1 0.21 0.92 0.21
98 INT8094 Positive_regulation of Gene_expression of BDKRB2 1 0.12 1.02 0.15
99 INT316232 Positive_regulation of Transcription of BDKRB2 1 0.23 0.7 0.09
100 INT316235 Transcription of BDKRB2 1 0.26 0.7 0.09
101 INT261684 Positive_regulation of Phosphorylation of BDKRB1 1 0.11 0.86 0.08
102 INT58888 Negative_regulation of Localization of Bdkrb1 1 0.43 0.5 0
103 INT124462 Negative_regulation of Regulation of BDKRB1 1 0.00 0.14 0
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