GO:0004948

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Name calcitonin receptor activity
Categary Function
Go Slim No
Go Link GO:0004948
Unique Molecular Interactions 66
Total Molecular Interactions 113
Total Single Events 484
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for calcitonin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for calcitonin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8
2 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
3 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
4 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
5 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41
6 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12
7 INT239539 Binding of CXCR2 and CALCRL 1 0.00 0.38 0.98
8 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
9 INT141965 Binding of ADM and CALCRL 5 0.33 3.6 0.89
10 INT141963 Binding of CALCRL and RAMP1 2 0.43 0.81 0.78
11 INT142507 Binding of Calca and Ramp1 1 0.31 0.48 0.73
12 INT157063 SLC12A1 Negative_regulation of CALCRL 1 0.00 0.34 0.73
13 INT239538 Binding of CXCR4 and CALCRL 1 0.00 0.35 0.71
14 INT116787 CALCRL Regulation of Trpv1 1 0.01 0 0.56
15 INT88889 Binding of HSPG2 and CALCRL 1 0.00 0 0.48
16 INT141964 Binding of ADM and RAMP1 1 0.30 2.63 0.47
17 INT138424 Binding of RAMP1 and Calca 1 0.01 0.08 0.47
18 INT194405 DCLK3 Positive_regulation of Gene_expression of RAMP1 1 0.16 0.09 0.43
19 INT91545 Binding of HTR1B and CALCRL 1 0.01 0.09 0.41
20 INT75149 Binding of CALCRL and ZNF594 1 0.00 0.08 0.39
21 INT136821 Binding of CALCRL and OGFR 1 0.02 0.36 0.38
22 INT53257 CALCRL Negative_regulation of Binding of Agt 1 0.00 0 0.36
23 INT224461 F2RL1 Positive_regulation of CALCRL 1 0.00 0.37 0.31
24 INT119334 Binding of Calcrl and Positive_regulation of Gpr182 1 0.19 0.13 0.3
25 INT194406 Binding of RAMP1 and RPL34P34 1 0.00 0 0.29
26 INT233786 Binding of CALCR and SCT 1 0.05 0 0.27
27 INT178578 Binding of PTHLH and CALCRL 1 0.01 0.68 0.27
28 INT63102 OXT Regulation of CALCRL 1 0.01 0.25 0.27
29 INT85012 CALCA Regulation of CALCRL 1 0.05 0 0.24
30 INT85011 ADM Regulation of CALCRL 1 0.06 0 0.24
31 INT31466 Binding of SGCG and CALCRL 1 0.02 0 0.23
32 INT23586 Binding of CALCR and KRIT1 1 0.40 0.97 0.19
33 INT172246 TAS2R14 Positive_regulation of Gene_expression of RAMP1 1 0.01 0.07 0.18
34 INT132264 Binding of SGCG and Calcrl 1 0.02 0.25 0.18
35 INT172251 CALCRL Positive_regulation of Gene_expression of RAMP1 1 0.04 0.07 0.17
36 INT294110 Binding of CALCRL and GOPC 1 0.00 0 0.17
37 INT172232 CALCRL Positive_regulation of Gene_expression of NRP1 1 0.02 0.07 0.17
38 INT294107 Binding of DMRT1 and CALCRL 1 0.00 0 0.15
39 INT222465 Binding of Calcrl and Rxfp2 1 0.02 0 0.12
40 INT206856 Binding of Adm and Calcrl 1 0.04 1.76 0.1
41 INT29223 Binding of NCOR2 and CALCRL 1 0.00 0 0.1
42 INT83589 Binding of CALCRL and Trh 1 0.01 0.18 0.07
43 INT222479 Binding of Ramp1 and Rxfp2 1 0.01 0 0.06
44 INT336993 Binding of PDIA3 and CALCRL 1 0.00 0 0.06
45 INT222559 Binding of Ramp3 and Ramp1 1 0.02 0 0.05
46 INT222485 Binding of Iapp and Ramp1 1 0.09 0 0.05
47 INT342387 Binding of CALCR and Car1 1 0.11 0.83 0
48 INT342388 Binding of CALCR and Vdr 1 0.12 0.83 0
49 INT334894 Binding of CALCR and ARMC9 1 0.01 0.41 0
50 INT270778 Binding of TNFSF11 and CALCRL 1 0.00 0.44 0
51 INT336989 Binding of GNAI1 and CALCRL 1 0.00 0 0
52 INT277897 EGF Positive_regulation of CALCRL 1 0.00 0.77 0
53 INT206899 ESR1 Negative_regulation of Gene_expression of Calcrl 1 0.07 0.15 0
54 INT109249 Calcrl Regulation of Ramp1 1 0.28 0.22 0
55 INT337011 Binding of CALCRL and Agtrap 1 0.00 0 0
56 INT342386 Binding of CALCR and Best1 1 0.01 0.96 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for calcitonin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in calcitonin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22068 Binding of CALCRL 53 0.41 6.14 17.32
2 INT42810 Gene_expression of CALCRL 53 0.77 10.87 15.42
3 INT63104 Negative_regulation of CALCRL 29 0.37 13.62 12.42
4 INT5464 Regulation of CALCRL 24 0.16 4.2 11.19
5 INT102448 Gene_expression of RAMP1 23 0.75 4.62 10.9
6 INT5465 Positive_regulation of CALCRL 25 0.49 7.24 9.8
7 INT120200 Binding of RAMP1 6 0.47 0.72 6.16
8 INT109246 Gene_expression of Calcrl 16 0.75 4.71 5.19
9 INT109248 Gene_expression of Ramp1 8 0.72 2.45 4.69
10 INT119330 Binding of Calcrl 8 0.37 1.96 3.85
11 INT102451 Localization of CALCRL 9 0.69 0 3.25
12 INT148934 Binding of Ramp1 4 0.36 0.94 2.89
13 INT142502 Gene_expression of Ramp1 5 0.67 2.23 2.72
14 INT103298 Binding of CALCR 5 0.47 6.03 2.15
15 INT194414 Positive_regulation of Gene_expression of RAMP1 4 0.60 0.57 1.89
16 INT148933 Localization of Ramp1 1 0.77 0.75 1.48
17 INT166595 Positive_regulation of Binding of RAMP1 2 0.45 0.18 1.36
18 INT148932 Localization of Calcrl 3 0.79 1.65 1.35
19 INT106834 Negative_regulation of Negative_regulation of CALCRL 1 0.01 0.16 1.3
20 INT142503 Positive_regulation of Gene_expression of Ramp1 1 0.43 0.83 1.26
21 INT23589 Positive_regulation of CALCR 9 0.67 6.73 1.25
22 INT157064 Negative_regulation of Regulation of CALCRL 2 0.02 0.33 1.18
23 INT161486 Regulation of Ramp1 2 0.61 1.64 1.16
24 INT194413 Positive_regulation of RAMP1 1 0.36 0.07 1.08
25 INT51994 Positive_regulation of Gene_expression of CALCRL 4 0.03 0.13 1.02
26 INT86800 Positive_regulation of Binding of CALCRL 3 0.37 0 1.01
27 INT223967 Regulation of Gene_expression of RAMP1 1 0.39 0.5 0.97
28 INT119324 Positive_regulation of Gene_expression of Ramp1 3 0.53 0.94 0.89
29 INT134654 Localization of CALCR 5 0.39 3.21 0.85
30 INT163889 Regulation of Gene_expression of Calcrl 3 0.21 1 0.84
31 INT3211 Positive_regulation of Calcrl 3 0.23 0.81 0.8
32 INT39820 Gene_expression of CALCR 16 0.37 4.96 0.74
33 INT23590 Regulation of CALCR 4 0.26 1.05 0.71
34 INT116786 Negative_regulation of Localization of CALCRL 1 0.01 0 0.61
35 INT3209 Regulation of Calcrl 3 0.26 1.31 0.6
36 INT3210 Negative_regulation of Calcrl 1 0.03 0.64 0.6
37 INT96689 Positive_regulation of Positive_regulation of CALCRL 1 0.01 0.08 0.59
38 INT142504 Positive_regulation of Ramp1 1 0.46 0.66 0.55
39 INT116785 Regulation of Localization of CALCRL 1 0.00 0 0.53
40 INT119329 Positive_regulation of Ramp1 1 0.43 0.2 0.48
41 INT53256 Negative_regulation of Binding of CALCRL 4 0.03 0.33 0.45
42 INT224479 Protein_catabolism of CALCRL 1 0.01 0.62 0.37
43 INT224502 Positive_regulation of Protein_catabolism of CALCRL 1 0.00 0.62 0.37
44 INT243867 Regulation of Negative_regulation of CALCRL 1 0.01 0 0.33
45 INT109245 Positive_regulation of Gene_expression of Calcrl 3 0.67 0.89 0.3
46 INT61468 Negative_regulation of CALCR 4 0.42 0.27 0.17
47 INT191797 Negative_regulation of Gene_expression of CALCR 2 0.03 1.37 0.17
48 INT206888 Negative_regulation of Gene_expression of Calcrl 2 0.26 0.83 0.13
49 INT191796 Positive_regulation of Gene_expression of CALCR 2 0.06 1.74 0.05
50 INT206890 Negative_regulation of Gene_expression of Ramp1 1 0.18 0.83 0.05
51 INT61469 Transcription of CALCR 3 0.43 1.37 0.04
52 INT222576 Regulation of Gene_expression of Ramp1 1 0.09 0 0.04
53 INT213679 Positive_regulation of Transcription of CALCR 1 0.30 1.37 0.04
54 INT289446 Transcription of CALCRL 1 0.01 0.1 0
55 INT206744 Negative_regulation of Phosphorylation of CALCRL 1 0.01 0.78 0
56 INT206743 Phosphorylation of CALCRL 1 0.01 0.78 0
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