GO:0004955

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Name prostaglandin receptor activity
Categary Function
Go Slim No
Go Link GO:0004955
Unique Molecular Interactions 68
Total Molecular Interactions 93
Total Single Events 883
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for prostaglandin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for prostaglandin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182563 Ptger2 Positive_regulation of Ptger1 1 0.22 1.4 1.64
2 INT160653 Binding of P2rx1 and Ptgfr 1 0.28 0.66 1.14
3 INT182550 Ptger1 Negative_regulation of Trpv1 1 0.35 0.73 1.12
4 INT182552 Ptgir Positive_regulation of Ptger1 1 0.15 1.31 1.02
5 INT182561 Ptger3 Positive_regulation of Ptger1 1 0.15 1.31 1.02
6 INT182556 Ptger4 Positive_regulation of Ptgir 1 0.08 1.31 1.02
7 INT182567 Ptger4 Positive_regulation of Ptger1 1 0.15 1.31 1.02
8 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
9 INT182554 Ptger2 Regulation of Ptger1 1 0.11 0.68 0.52
10 INT342689 Ptger4 Positive_regulation of Prkaca 1 0.03 0.24 0.51
11 INT107703 PPARG Regulation of Gene_expression of CPOX 1 0.16 0.15 0.41
12 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
13 INT43331 Binding of Oxt and Ptgfr 1 0.01 0.37 0.37
14 INT43332 Positive_regulation of Binding of Oxt and Ptgfr 1 0.02 0.37 0.37
15 INT272733 Binding of Ptger2 and Ptgfr 1 0.01 1.31 0.34
16 INT304320 Binding of Ptger2 and Ptger4 2 0.26 0.06 0.33
17 INT122169 AKR1C3 Regulation of PPARG 1 0.45 0.26 0.33
18 INT148556 PPARG Regulation of Gene_expression of PPARA 1 0.30 1.2 0.31
19 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
20 INT289766 Pgf Positive_regulation of Ptgfr 1 0.04 0.07 0.31
21 INT110373 CYP4A11 Positive_regulation of PPARG 1 0.00 0.94 0.26
22 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
23 INT272731 Ptger2 Positive_regulation of Gene_expression of Ptgfr 1 0.01 0.65 0.25
24 INT130060 PPARG Positive_regulation of Positive_regulation of Egr1 1 0.22 0.46 0.24
25 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23
26 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23
27 INT115148 PPARG Negative_regulation of Gene_expression of INSIG2 1 0.01 0.34 0.21
28 INT272737 Positive_regulation of Binding of Ptger2 and Ptgfr 1 0.01 0.36 0.2
29 INT69868 Binding of Ptgds and Ptger1 1 0.01 0 0.18
30 INT272729 Ptger2 Positive_regulation of Ptgfr 1 0.01 0.3 0.17
31 INT25400 Binding of Ptger1 and Ptger2 2 0.11 1.02 0.15
32 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14
33 INT115140 PPARG Positive_regulation of EGR1 1 0.36 0.45 0.13
34 INT109410 RASGRP1 Regulation of Gene_expression of PPARG 1 0.03 0.76 0.13
35 INT115145 PPARG Positive_regulation of TFAM 1 0.04 0.45 0.13
36 INT253468 Ptger2 Positive_regulation of Ptger4 1 0.12 1.19 0.13
37 INT272727 Negative_regulation of Binding of Ptger2 and Ptgfr 1 0.01 0.36 0.1
38 INT157265 PPARG Positive_regulation of PPARA 1 0.22 1.15 0.09
39 INT157276 PPARG Positive_regulation of Adipoq 1 0.29 1.09 0.09
40 INT289603 Sirt1 Negative_regulation of Localization of PPARG 1 0.02 0.43 0.08
41 INT289602 Sirt1 Negative_regulation of PPARG 1 0.02 0.37 0.07
42 INT332641 Binding of PPARG and Ins1 1 0.12 1.05 0.05
43 INT289767 Ptgfr Positive_regulation of Positive_regulation of Pgf 1 0.03 0 0.05
44 INT289763 Ptgfr Positive_regulation of Gene_expression of Sat1 1 0.04 0 0.04
45 INT263337 Ptger4 Regulation of Ppara 1 0.02 0.3 0.04
46 INT331964 Binding of Ptger3 and Ptgfr 1 0.01 0.15 0.03
47 INT331959 Binding of Ptger4 and Ptgfr 1 0.01 0.15 0.03
48 INT331962 Positive_regulation of Binding of Ptger3 and Ptgfr 1 0.01 0.15 0.03
49 INT348592 Binding of HDAC1 and PPARG 1 0.23 0 0.03
50 INT331963 Positive_regulation of Binding of Ptger4 and Ptgfr 1 0.01 0.15 0.03
51 INT348583 MECP2 Regulation of PPARG 1 0.46 0.73 0
52 INT348594 MECP2 Regulation of Gene_expression of PPARG 1 0.34 0.43 0
53 INT290027 Binding of PPARG and NR1H4 1 0.03 0.39 0
54 INT348584 EZH2 Regulation of Gene_expression of PPARG 1 0.30 0.43 0
55 INT290031 Binding of INS and PPARG 1 0.11 0.47 0
56 INT290022 Binding of PPARG and DDX12P 1 0.00 1.77 0
57 INT348593 ZACN Regulation of Positive_regulation of PPARG 1 0.14 0.41 0
58 INT344893 Binding of ADCY1 and Ptger4 1 0.00 0 0
59 INT290030 Binding of PPARD and PPARG 1 0.09 0.38 0
60 INT290024 Binding of PPARG and RXRG 1 0.15 0.39 0
61 INT348587 Binding of MECP2 and PPARG 1 0.32 0.25 0
62 INT348586 RSPH1 Positive_regulation of Gene_expression of PPARG 1 0.02 0.23 0
63 INT290026 Binding of PPARG and CHDH 1 0.10 6.61 0
64 INT348585 EZH2 Regulation of PPARG 1 0.41 0.73 0
65 INT348595 Binding of PPARG and ZACN 1 0.07 0.38 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for prostaglandin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in prostaglandin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38
2 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42
3 INT3057 Gene_expression of Ptgfr 60 0.58 14.54 11.73
4 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64
5 INT67612 Binding of PPARG 38 0.48 22.67 8.94
6 INT64280 Positive_regulation of Ptger1 22 0.67 14.9 7.49
7 INT68959 Gene_expression of Ptger1 34 0.67 11.68 7.04
8 INT100078 Positive_regulation of Positive_regulation of PPARG 11 0.70 3.6 5.86
9 INT904 Positive_regulation of Ptgfr 23 0.49 7.98 5.55
10 INT22202 Localization of Ptgfr 15 0.68 4.59 5.47
11 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4
12 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31
13 INT127428 Negative_regulation of Ptger1 8 0.42 5.26 4.15
14 INT139970 Localization of Ptger1 12 0.75 7.35 3.41
15 INT4057 Negative_regulation of Ptgfr 9 0.32 3.28 3
16 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99
17 INT3056 Positive_regulation of Gene_expression of Ptgfr 15 0.40 3.41 2.98
18 INT18128 Binding of Ptgfr 7 0.36 2.69 2.97
19 INT44796 Binding of Ptger1 11 0.45 5.25 2.9
20 INT68962 Positive_regulation of Ptger4 20 0.67 7.3 2.79
21 INT905 Regulation of Ptgfr 8 0.35 2.87 2.28
22 INT45860 Positive_regulation of Binding of Ptgfr 3 0.49 1.8 2.22
23 INT169786 Localization of Ptger4 7 0.69 1.82 1.65
24 INT64279 Regulation of Ptger1 2 0.41 1.54 1.65
25 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62
26 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55
27 INT27804 Negative_regulation of Gene_expression of Ptgfr 7 0.34 1.03 1.43
28 INT140877 Regulation of Ptger4 6 0.36 2.2 1.23
29 INT130474 Phosphorylation of Ptger1 2 0.45 1.73 1.22
30 INT130473 Negative_regulation of Phosphorylation of Ptger1 1 0.31 0.67 1.22
31 INT95800 Positive_regulation of Positive_regulation of Ptger1 2 0.43 1.23 1.15
32 INT27409 Negative_regulation of Localization of Ptgfr 6 0.46 2.06 1.13
33 INT79689 Regulation of PPARG 10 0.62 8.04 1.07
34 INT155465 Positive_regulation of Negative_regulation of Ptger1 1 0.43 1.34 1.01
35 INT182536 Positive_regulation of Gene_expression of Ptger1 3 0.36 2.82 0.96
36 INT107714 Localization of PPARG 4 0.73 0.88 0.91
37 INT169788 Negative_regulation of Ptger4 5 0.51 2.11 0.82
38 INT169792 Positive_regulation of Gene_expression of Ptger4 5 0.60 2 0.82
39 INT182544 Regulation of Gene_expression of Ptger1 1 0.32 0.09 0.75
40 INT77591 Binding of Ptger4 3 0.36 1.09 0.74
41 INT169790 Negative_regulation of Localization of Ptger4 1 0.37 0.77 0.72
42 INT169784 Regulation of Localization of Ptger4 1 0.39 0.77 0.72
43 INT169789 Regulation of Negative_regulation of Ptger1 1 0.44 0.77 0.72
44 INT110089 Positive_regulation of Binding of PPARG 1 0.70 1.04 0.7
45 INT93530 Transcription of Ptger1 8 0.42 0.54 0.64
46 INT165706 Negative_regulation of Negative_regulation of PPARG 3 0.23 1.05 0.58
47 INT115156 Regulation of Positive_regulation of PPARG 2 0.25 0.86 0.54
48 INT46188 Regulation of Localization of Ptgfr 2 0.15 0.52 0.53
49 INT73624 Transcription of PPARG 7 0.72 3.25 0.49
50 INT86132 Transcription of Ptger4 4 0.47 0.85 0.49
51 INT54743 Positive_regulation of Localization of Ptgfr 2 0.04 0.91 0.47
52 INT46348 Protein_catabolism of Ptgfr 1 0.11 0.27 0.47
53 INT4362 Positive_regulation of Positive_regulation of Ptgfr 3 0.06 0.41 0.38
54 INT68965 Positive_regulation of Positive_regulation of Ptger4 3 0.43 1.43 0.37
55 INT107713 Positive_regulation of Localization of PPARG 1 0.59 0.07 0.36
56 INT139969 Positive_regulation of Localization of Ptger1 1 0.50 1.05 0.32
57 INT304318 Negative_regulation of Gene_expression of Ptger4 1 0.34 0 0.29
58 INT272704 Regulation of Gene_expression of Ptgfr 2 0.08 0.07 0.28
59 INT95801 Positive_regulation of Binding of Ptger1 1 0.43 0.25 0.28
60 INT182539 Regulation of Regulation of Ptger1 1 0.19 0 0.23
61 INT80614 Regulation of Binding of Ptgfr 1 0.14 0.18 0.18
62 INT4361 Regulation of Positive_regulation of Ptgfr 3 0.06 0.28 0.14
63 INT115155 Phosphorylation of PPARG 1 0.58 0.44 0.13
64 INT263333 Regulation of Gene_expression of Ptger4 1 0.15 0.3 0.04
65 INT93529 Negative_regulation of Gene_expression of Ptger1 1 0.28 0.32 0.04
66 INT344887 Negative_regulation of Binding of Ptger4 1 0.28 0 0
67 INT272707 Positive_regulation of Regulation of Ptgfr 1 0.04 0.15 0
68 INT17116 Negative_regulation of Positive_regulation of Ptgfr 1 0.00 0.1 0
69 INT290036 Regulation of Binding of PPARG 1 0.45 0.66 0
70 INT348617 Regulation of Negative_regulation of PPARG 1 0.24 0.42 0
71 INT332933 Regulation of Transcription of PPARG 1 0.43 1.71 0
72 INT332925 Protein_catabolism of PPARG 1 0.63 1.04 0
73 INT337981 Transcription of Ptgfr 1 0.18 0.83 0
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