GO:0004965

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Name G-protein coupled GABA receptor activity
Categary Function
Go Slim No
Go Link GO:0004965
Unique Molecular Interactions 49
Total Molecular Interactions 65
Total Single Events 809
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for G-protein coupled GABA receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for G-protein coupled GABA receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT179443 Vta1 Positive_regulation of Gpr156 1 0.20 0 1.99
2 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94
3 INT179444 Hmmr Negative_regulation of Gpr156 1 0.03 0 1.79
4 INT245349 Binding of Abat and Gpr156 1 0.02 0.26 1
5 INT137321 Gabrg1 Negative_regulation of Positive_regulation of Gabbr1 1 0.22 0 0.75
6 INT244062 Gabrg1 Regulation of Gabbr1 1 0.01 0.09 0.74
7 INT264775 Binding of Gabbr1 and Abat 1 0.03 0 0.64
8 INT161996 Binding of Gabbr2 and Fbxo23 1 0.29 0.15 0.33
9 INT352055 Negative_regulation of Binding of Spn and Gpr156 1 0.09 0.28 0.31
10 INT352054 Binding of Spn and Gpr156 1 0.08 0.28 0.31
11 INT132585 GABBR1 Positive_regulation of Binding of Gabbr1 1 0.01 0.6 0.3
12 INT251388 Binding of Fbln2 and Gabbr1 1 0.08 0.07 0.3
13 INT56984 Positive_regulation of Gabbr1 Positive_regulation of Positive_regulation of CSN3 1 0.06 0.07 0.25
14 INT73969 Positive_regulation of Gabbr1 Regulation of Gabrd 1 0.01 0 0.23
15 INT264776 Abat Positive_regulation of Gabbr1 1 0.03 0.06 0.22
16 INT264778 Binding of CA2 and Gabbr1 1 0.02 0 0.21
17 INT307651 Gabbr1 Regulation of Gene_expression of Bdnf 1 0.00 0 0.16
18 INT307652 Gabbr1 Regulation of Localization of Bdnf 1 0.00 0 0.16
19 INT284858 Binding of Gabbr1 and Pdzd2 1 0.03 0.24 0.15
20 INT284856 Regulation of Binding of Gabbr1 and Pdzd2 1 0.04 0.24 0.15
21 INT352057 Spns1 Regulation of Gpr156 1 0.06 0 0.12
22 INT276061 Gabbr2 Negative_regulation of Prkaca 1 0.09 0 0.11
23 INT276041 Positive_regulation of Gabbr2 Negative_regulation of Positive_regulation of Rpa1 1 0.01 0 0.1
24 INT251389 Binding of Gabbr1 and Sds 1 0.23 0.32 0.1
25 INT119859 Gabbr1 Positive_regulation of INSRR 1 0.00 0 0.09
26 INT73968 Gabbr1 Regulation of Gabrd 1 0.01 0 0.09
27 INT276066 Gabbr2 Negative_regulation of Positive_regulation of Rpa1 1 0.01 0 0
28 INT209708 Binding of GABBR1 and GTPBP4 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for G-protein coupled GABA receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in G-protein coupled GABA receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22
2 INT12441 Positive_regulation of Gpr156 29 0.67 5.7 24.44
3 INT26116 Gene_expression of Gpr156 31 0.78 13.97 20.59
4 INT6351 Positive_regulation of Gabbr1 40 0.64 11.99 19
5 INT5476 Regulation of Gabbr1 21 0.45 4.01 10.26
6 INT6356 Binding of Gabbr1 30 0.48 4.62 9.82
7 INT43734 Negative_regulation of Gpr156 11 0.43 1.42 8.89
8 INT6352 Negative_regulation of Gabbr1 7 0.59 4.84 7.93
9 INT12440 Regulation of Gpr156 11 0.45 3.2 6.07
10 INT116277 Transcription of Gpr156 7 0.53 2.53 5.61
11 INT43506 Regulation of Gene_expression of Gabbr1 2 0.61 4.88 5.52
12 INT264765 Positive_regulation of Gene_expression of Gabbr1 2 0.70 4.88 5.07
13 INT143218 Binding of Gpr156 6 0.48 0.41 4.5
14 INT117244 Gene_expression of GABBR1 5 0.33 2.19 4.36
15 INT85288 Gene_expression of Gabbr2 5 0.76 2.39 3.41
16 INT16562 Negative_regulation of Positive_regulation of Gabbr1 5 0.43 2.67 3.24
17 INT20716 Localization of Gpr156 6 0.46 1.7 3.12
18 INT275367 Positive_regulation of Gene_expression of Gpr156 3 0.26 2.15 2.85
19 INT54495 Binding of GABBR1 9 0.35 1.82 2.76
20 INT119855 Localization of Gabbr1 21 0.79 3.15 2.7
21 INT13245 Regulation of Positive_regulation of Gpr156 4 0.33 0.87 2.65
22 INT33145 Binding of Gabbr2 1 0.48 0.98 2.48
23 INT64567 Negative_regulation of Positive_regulation of Gpr156 4 0.36 0.63 2.34
24 INT114773 Negative_regulation of GABBR1 4 0.43 0.55 2.33
25 INT33147 Positive_regulation of Gabbr2 4 0.50 0.32 2.32
26 INT58352 Negative_regulation of Gene_expression of Gabbr1 5 0.43 1.36 2.05
27 INT29831 Positive_regulation of Gabbr2 2 0.26 0.5 1.88
28 INT6353 Positive_regulation of Positive_regulation of Gabbr1 2 0.46 0.79 1.85
29 INT116276 Positive_regulation of Transcription of Gpr156 2 0.47 0.51 1.85
30 INT33144 Positive_regulation of Binding of Gabbr2 1 0.69 0.65 1.63
31 INT116275 Regulation of Gene_expression of Gpr156 2 0.62 0.95 1.62
32 INT85289 Positive_regulation of Gene_expression of Gabbr2 2 0.49 0.75 1.6
33 INT48775 Regulation of Gabbr2 3 0.41 0.15 1.55
34 INT245346 Positive_regulation of Binding of Gpr156 1 0.06 0.18 1.51
35 INT179440 Positive_regulation of Localization of Gpr156 2 0.31 0.27 1.43
36 INT96372 Gene_expression of Gabbr2 4 0.45 0.22 1.42
37 INT55108 Negative_regulation of Negative_regulation of Gabbr1 1 0.02 0 1.35
38 INT96373 Negative_regulation of Gene_expression of Gabbr2 1 0.06 0 1.22
39 INT1867 Positive_regulation of GABBR1 6 0.69 0.55 1.18
40 INT118632 Binding of Gabbr2 2 0.32 0.25 1.12
41 INT6355 Regulation of Positive_regulation of Gabbr1 1 0.27 0 0.96
42 INT33146 Negative_regulation of Binding of Gabbr2 1 0.43 0.33 0.86
43 INT275366 Negative_regulation of Gene_expression of Gpr156 5 0.22 3.64 0.85
44 INT131756 Regulation of Transcription of Gpr156 1 0.01 0.29 0.83
45 INT85290 Regulation of Gene_expression of Gabbr2 1 0.44 0.74 0.8
46 INT100639 Regulation of Gabbr2 1 0.45 0.4 0.75
47 INT117246 Transcription of GABBR1 1 0.38 0.07 0.72
48 INT264628 Regulation of GABBR1 3 0.26 1.39 0.62
49 INT143219 Negative_regulation of Binding of Gpr156 2 0.37 0 0.59
50 INT251386 Transcription of Gabbr1 4 0.68 0.22 0.58
51 INT75420 Regulation of Binding of Gabbr1 1 0.01 0 0.54
52 INT65348 Negative_regulation of Regulation of Gabbr1 1 0.16 0 0.43
53 INT352053 Positive_regulation of Positive_regulation of Gpr156 1 0.36 0.13 0.36
54 INT143220 Regulation of Binding of Gpr156 1 0.61 0 0.34
55 INT275363 Negative_regulation of Gabbr2 1 0.04 1.82 0.18
56 INT276015 Regulation of Positive_regulation of Gabbr2 1 0.14 0.41 0.16
57 INT251380 Regulation of Localization of Gabbr1 1 0.27 0.07 0.15
58 INT20717 Regulation of Localization of Gpr156 1 0.14 0 0.1
59 INT260469 Localization of Gabbr2 1 0.43 0.11 0.1
60 INT260453 Negative_regulation of Localization of Gabbr2 1 0.25 0.12 0.1
61 INT331160 Localization of GABBR1 1 0.17 0.07 0.09
62 INT275365 Negative_regulation of Gene_expression of Gabbr2 1 0.04 0.91 0.09
63 INT251384 Negative_regulation of Binding of Gabbr1 1 0.42 0 0.07
64 INT276020 Negative_regulation of Positive_regulation of Gabbr2 1 0.13 0 0.04
65 INT321996 Positive_regulation of Regulation of GABBR1 1 0.45 0 0
66 INT276005 Positive_regulation of Gene_expression of Gabbr2 1 0.16 0 0
67 INT251381 Negative_regulation of Transcription of Gabbr1 1 0.42 0 0
68 INT251382 Positive_regulation of Localization of Gabbr1 1 0.46 0.07 0
69 INT262121 Localization of Gabbr2 1 0.01 0.14 0
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