GO:0004970

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Name ionotropic glutamate receptor activity
Categary Function
Go Slim No
Go Link GO:0004970
Unique Molecular Interactions 769
Total Molecular Interactions 1069
Total Single Events 10837
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ionotropic glutamate receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for ionotropic glutamate receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
2 INT251146 Binding of Grin1 and Dlg2 1 0.36 1.95 3.16
3 INT101408 Binding of Grin1 and Olr1469 1 0.03 0.86 3.1
4 INT101407 Binding of Grin1 and Spr 1 0.14 0.86 3.09
5 INT102284 Binding of Grin1 and Grin2a 5 0.27 1.79 3.01
6 INT156381 Binding of Grin1 and Dlg4 1 0.39 0.86 2.9
7 INT170367 Binding of Grin1 and Grin2a 5 0.23 1.72 2.79
8 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
9 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48
10 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
11 INT251147 Binding of Grin2b and Dlg2 1 0.33 2.75 2.43
12 INT107578 Kitl Negative_regulation of Grin2b 1 0.12 2.05 2.36
13 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21
14 INT251145 Binding of Grin2a and Dlg2 1 0.31 2.3 2.11
15 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93
16 INT120732 Prkcg Positive_regulation of Phosphorylation of Grin1 2 0.48 1.04 1.81
17 INT272616 Positive_regulation of Binding of Grin1 and Grin2a 2 0.30 1.36 1.8
18 INT332773 Positive_regulation of Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.04 0.73 1.75
19 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
20 INT131575 Grin1 Negative_regulation of Positive_regulation of Ephb1 1 0.28 0.31 1.58
21 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
22 INT148821 Binding of Oprm1 and Grin1 1 0.05 0.24 1.55
23 INT249498 Src Positive_regulation of Phosphorylation of Grin2b 1 0.22 1.11 1.54
24 INT140329 Grin1 Negative_regulation of Ltp 1 0.04 0.64 1.46
25 INT161871 Mors1 Positive_regulation of GRIN1 1 0.01 0.12 1.46
26 INT161858 OPRM1 Positive_regulation of GRIN1 1 0.50 0.12 1.45
27 INT246519 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.25 0.08 1.42
28 INT293200 Positive_regulation of Grin1 Positive_regulation of Phosphorylation of Grin2b 1 0.24 0.4 1.39
29 INT138099 Binding of Grin2a and Insrr 1 0.01 0.36 1.39
30 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31
31 INT57262 Binding of Gria4 and Oprd1 1 0.06 0 1.29
32 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
33 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
34 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22
35 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
36 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
37 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
38 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
39 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14
40 INT122267 Prkcg Positive_regulation of Grin2b 1 0.26 0.61 1.14
41 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14
42 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
43 INT163799 Binding of GRIN1 and Rvm 1 0.16 0.96 1.13
44 INT332776 FSCN1 Positive_regulation of Grin1 1 0.02 0.21 1.12
45 INT132683 Bdnf Positive_regulation of Phosphorylation of Grin2a 1 0.00 0.93 1.11
46 INT122268 Binding of Grin2b and Grm5 1 0.40 0.52 1.1
47 INT193328 Grid1 Regulation of Positive_regulation of Prkcg 1 0.00 0.1 1.1
48 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09
49 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09
50 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08
51 INT256294 Binding of Grin2b and Ephb1 1 0.28 1.11 1.08
52 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
53 INT269193 Prkcg Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
54 INT269192 Ephb1 Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
55 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
56 INT269198 Prkaca Regulation of Phosphorylation of Grin2a 1 0.02 0.63 1.06
57 INT291966 Pag1 Positive_regulation of Gene_expression of Grin2b 1 0.19 1.91 1.06
58 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05
59 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05
60 INT256293 Binding of Grin2b and Insrr 1 0.01 1.06 1.05
61 INT269199 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.03 0.56 1.05
62 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04
63 INT291964 Phex Regulation of Gene_expression of Grin2b 1 0.08 1.39 1.04
64 INT346835 Gene_expression of Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.27 1.07 1.03
65 INT269194 Ceacam3 Positive_regulation of Phosphorylation of Grin1 1 0.09 0.55 1.02
66 INT131889 gr Regulation of Gene_expression of Grin1 1 0.02 0 1.01
67 INT186161 Prkaca Positive_regulation of Phosphorylation of Grin1 1 0.11 1.05 1.01
68 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
69 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1
70 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98
71 INT344389 Ephb2 Positive_regulation of Phosphorylation of Grin2b 1 0.16 1.46 0.98
72 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98
73 INT353372 Dio1 Positive_regulation of Grin1 1 0.16 0 0.98
74 INT156380 Regulation of Binding of Grin1 and Dlg4 1 0.29 0.32 0.97
75 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
76 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94
77 INT344381 Olfr360 Negative_regulation of Gene_expression of Grin2b 1 0.01 1.17 0.93
78 INT344390 Olfr360 Negative_regulation of Phosphorylation of Grin2b 1 0.01 1.17 0.93
79 INT271635 Negative_regulation of GRIN1 Negative_regulation of Positive_regulation of Ltp 1 0.00 0.65 0.93
80 INT344388 Efnb1 Positive_regulation of Phosphorylation of Grin2b 1 0.40 1.45 0.92
81 INT122269 Src Negative_regulation of Positive_regulation of Grin2b 1 0.27 0.44 0.92
82 INT251153 Dlg2 Positive_regulation of Gene_expression of Grin2a 1 0.40 0.6 0.92
83 INT251152 Dlg2 Positive_regulation of Localization of Grin2b 1 0.43 0.6 0.92
84 INT291962 Pag1 Negative_regulation of Gene_expression of Grin2b 1 0.17 1.56 0.92
85 INT77330 Oprk1 Regulation of Localization of GRIN1 1 0.24 0 0.91
86 INT122266 Src Negative_regulation of Grin2b 1 0.27 0.43 0.91
87 INT281082 Binding of Gria2 and Ltp 1 0.24 0.6 0.9
88 INT281089 Binding of Gria1 and Ltp 1 0.25 0.6 0.9
89 INT108647 Binding of Grin2a and Camk1d 1 0.33 0.78 0.9
90 INT108438 Grin2b Regulation of Pdyn 1 0.16 0.25 0.9
91 INT165540 NGF Positive_regulation of GRIN1 1 0.07 0.17 0.88
92 INT315769 GRIN1 Negative_regulation of Plbd1 1 0.00 0.57 0.87
93 INT52195 Sigmar1 Positive_regulation of Positive_regulation of Grin1 1 0.15 0 0.87
94 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83
95 INT257895 Positive_regulation of Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
96 INT257896 Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
97 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82
98 INT98479 Lif Regulation of Gene_expression of Grin1 1 0.04 0.35 0.82
99 INT100559 Binding of Grin1 and LOC502940 1 0.13 0.61 0.8
100 INT54800 Grin1 Regulation of Gene_expression of Gh 1 0.01 0 0.79
101 INT214876 Ap3d1 Negative_regulation of Gria1 1 0.00 0.4 0.78
102 INT261413 Positive_regulation of GRIN1 Positive_regulation of Positive_regulation of Creb1 1 0.00 0.81 0.77
103 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77
104 INT164996 Ins1 Regulation of Gria2 1 0.05 0.05 0.76
105 INT311525 Binding of Gria1 and Ltp 1 0.00 0.1 0.73
106 INT296285 Binding of Car1 and Grin2b 1 0.14 0.32 0.72
107 INT186160 Negative_regulation of Grin2b Negative_regulation of Grin1 1 0.37 0.5 0.72
108 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72
109 INT296292 Binding of Car1 and Grin2a 1 0.14 0.32 0.72
110 INT296289 Grin2a Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
111 INT296290 Binding of Car1 and Grin1 1 0.11 0.32 0.72
112 INT296282 Grin2b Regulation of Negative_regulation of Kcnip3 1 0.30 0.3 0.72
113 INT197234 Grik1 Positive_regulation of Localization of Gabrg1 1 0.15 0.82 0.71
114 INT296295 Binding of Grin1 and Grin2b 1 0.16 0.31 0.71
115 INT296298 Grin2b Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
116 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
117 INT296288 Grin2a Regulation of Negative_regulation of Hmmr 1 0.03 0.29 0.71
118 INT51433 Gria1 Positive_regulation of Eif3g 1 0.03 0 0.7
119 INT335596 Positive_regulation of Grin2b Positive_regulation of Positive_regulation of Car2 1 0.12 0.19 0.69
120 INT102344 Grin1 Regulation of Localization of C3orf52 1 0.00 0 0.68
121 INT249485 Trib3 Negative_regulation of Phosphorylation of Grin2b 1 0.02 0.64 0.68
122 INT114036 Binding of Grin1 and Psd 1 0.24 0.45 0.68
123 INT162224 Grin1 Positive_regulation of Gene_expression of Gria1 1 0.27 0.07 0.66
124 INT162223 Grin1 Positive_regulation of Localization of Gria2 1 0.23 0.07 0.66
125 INT250084 Negative_regulation of Grin2b Negative_regulation of Positive_regulation of Ltp 1 0.18 0.07 0.66
126 INT249489 Src Negative_regulation of Phosphorylation of Grin2b 1 0.20 0.63 0.66
127 INT250078 Negative_regulation of Grin2b Negative_regulation of Ltp 1 0.18 0.07 0.66
128 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
129 INT197240 Grik2 Regulation of Gene_expression of Gabrg1 1 0.08 0.13 0.64
130 INT197238 Grik1 Regulation of Gene_expression of Gabrg1 1 0.17 0.13 0.64
131 INT197236 Grik2 Regulation of Gabrg1 1 0.08 0.13 0.64
132 INT302441 Binding of GRIN1 and Grin2b 1 0.10 1.27 0.63
133 INT236003 Binding of HTR1A and Grin1 1 0.01 0.7 0.63
134 INT186159 Grin2d Negative_regulation of Grin2b 1 0.21 0.82 0.62
135 INT86405 MMD Positive_regulation of GRIN1 1 0.54 0 0.62
136 INT249484 Trib3 Positive_regulation of Phosphorylation of Grin2b 1 0.01 0.57 0.61
137 INT197239 Grik1 Regulation of Localization of Gabrg1 1 0.10 0.56 0.61
138 INT281079 Binding of Nsf and Gria3 1 0.19 0.05 0.61
139 INT201294 Negative_regulation of Grik1 Negative_regulation of Gabrg1 1 0.30 0 0.6
140 INT296463 Binding of Gria1 and Pick1 1 0.16 0.32 0.59
141 INT281093 GRIN1 Positive_regulation of Positive_regulation of Ltp 1 0.30 0 0.58
142 INT112107 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2a 1 0.40 0.49 0.57
143 INT134532 Grin2a Regulation of Ngfr 1 0.02 0 0.57
144 INT296456 Gria1 Negative_regulation of Rbm39 1 0.00 0.45 0.57
145 INT134528 Grin1 Regulation of Ngfr 1 0.03 0 0.57
146 INT134531 Gria1 Regulation of Ngfr 1 0.01 0 0.57
147 INT296446 Binding of Gria2 and Gria4 1 0.13 0.55 0.57
148 INT134530 Grin1 Regulation of Gria1 1 0.12 0 0.56
149 INT112106 Negative_regulation of Dlg2 Negative_regulation of Grin2a 1 0.40 0.48 0.56
150 INT311524 Gnrhr Positive_regulation of Transcription of Grin2a 1 0.02 0.54 0.55
151 INT281087 Binding of Gria1 and Hmmr 1 0.04 0 0.55
152 INT343597 Gys1 Regulation of Transcription of Gria2 1 0.00 0 0.55
153 INT251141 Binding of Dlg4 and Grin2b 1 0.14 0.32 0.55
154 INT296462 Prkca Positive_regulation of Phosphorylation of Gria2 1 0.15 0.3 0.55
155 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
156 INT251143 Binding of Grin2b and Dlg3 1 0.22 0.32 0.55
157 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54
158 INT263776 Grin1 Positive_regulation of Ltp 2 0.17 0.17 0.54
159 INT251151 Binding of Grin2a and Dlg3 1 0.24 0.32 0.54
160 INT311521 Gnrhr Positive_regulation of Gene_expression of Gria1 1 0.00 0.54 0.54
161 INT311522 Gnrhr Positive_regulation of Transcription of Gria1 1 0.00 0.54 0.54
162 INT249497 Efnb2 Positive_regulation of Phosphorylation of Grin2b 1 0.02 0.51 0.54
163 INT296485 Negative_regulation of Binding of Gria2 and GRIP1 1 0.05 0.3 0.54
164 INT249479 Binding of Ephb1 and Grin2b 1 0.29 0.37 0.54
165 INT291386 Cntf Regulation of Gene_expression of Gria2 1 0.11 0.13 0.53
166 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52
167 INT349130 Phosphorylation of Gria1 Positive_regulation of Shisa9 1 0.00 0.49 0.52
168 INT208121 Binding of Grin2a and Grin2b 3 0.35 0.06 0.51
169 INT76068 Gal Positive_regulation of Grin1 1 0.34 0 0.51
170 INT208122 Grin2a Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
171 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
172 INT250080 Grin2b Positive_regulation of Ltp 1 0.22 0.19 0.49
173 INT235090 Positive_regulation of GRIN1 Positive_regulation of NOS1 1 0.42 0.81 0.49
174 INT208119 Grin2b Positive_regulation of Positive_regulation of Ltp 1 0.16 0.21 0.49
175 INT296457 Camk2a Positive_regulation of Phosphorylation of Gria1 1 0.19 0.28 0.49
176 INT250082 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Grin1 1 0.03 0.08 0.49
177 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
178 INT259183 Gria1 Positive_regulation of Phosphorylation of Gria2 1 0.30 0.39 0.49
179 INT250081 Grin2a Positive_regulation of Ltp 1 0.20 0.14 0.48
180 INT283736 Tbs1 Positive_regulation of Grin1 1 0.04 0 0.48
181 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48
182 INT208120 Binding of Grin2a and Hpcal1 1 0.10 0.07 0.48
183 INT116337 Binding of GRIN1 and NDOR1 1 0.03 0 0.48
184 INT71318 Grik4 Positive_regulation of Localization of Npy 1 0.05 0 0.47
185 INT273110 Bdnf Regulation of Positive_regulation of Gria1 1 0.43 0 0.47
186 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
187 INT249486 Positive_regulation of Ephb1 Positive_regulation of Phosphorylation of Grin2b 1 0.33 0.4 0.46
188 INT127392 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin1 1 0.08 0.71 0.45
189 INT127397 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin1 1 0.01 0.71 0.45
190 INT250083 Positive_regulation of Ltp Positive_regulation of Grin1 1 0.03 0 0.45
191 INT127394 Negative_regulation of Ephb1 Negative_regulation of Gene_expression of Grin2a 1 0.01 0.71 0.45
192 INT127396 Negative_regulation of Mdk Negative_regulation of Gene_expression of Grin2a 1 0.00 0.71 0.45
193 INT291963 Phex Negative_regulation of Gene_expression of Grin1 1 0.06 0.81 0.43
194 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
195 INT63372 Grin1 Regulation of Localization of Abat 1 0.20 0 0.43
196 INT86069 Positive_regulation of Gria1 Positive_regulation of Gene_expression of Fos 1 0.11 0.3 0.42
197 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42
198 INT74713 Binding of Gria1 and Olr1868 1 0.00 0 0.42
199 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42
200 INT139654 Ntf3 Regulation of Gene_expression of Grin1 1 0.56 0.11 0.41

Single Events

The table below shows the top 100 pain related interactions that have been reported for ionotropic glutamate receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in ionotropic glutamate receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT49134 Gene_expression of Grin1 270 0.78 84.78 148.61
2 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24
3 INT7341 Positive_regulation of Grin1 169 0.70 65.86 118.38
4 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48
5 INT92518 Gene_expression of Grin2b 131 0.78 65.52 80.91
6 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
7 INT79506 Gene_expression of Grin2b 122 0.78 43.71 73.42
8 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06
9 INT90911 Positive_regulation of Phosphorylation of Grin1 62 0.70 27.45 59.26
10 INT7340 Regulation of Grin1 87 0.62 30.37 57.93
11 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
12 INT4957 Negative_regulation of Grin1 87 0.59 24.51 53.21
13 INT51627 Gene_expression of Grin2a 82 0.76 25.09 47.6
14 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31
15 INT94029 Positive_regulation of Grin2b 58 0.70 24.2 42.52
16 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43
17 INT92515 Gene_expression of Grin2a 84 0.76 26.68 38.37
18 INT82054 Positive_regulation of Grin2b 56 0.70 17.45 37.14
19 INT11246 Binding of Grin1 65 0.48 14.53 36.93
20 INT103998 Positive_regulation of Phosphorylation of Grin2b 33 0.69 19.08 36.08
21 INT130479 Phosphorylation of Grin2b 28 0.77 34.82 34.97
22 INT52194 Positive_regulation of Grin1 83 0.69 25.09 34.76
23 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24
24 INT57024 Regulation of Gene_expression of Grin1 32 0.62 9.77 32.6
25 INT93451 Positive_regulation of Gene_expression of Grin2b 43 0.70 29.09 31.89
26 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
27 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
28 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
29 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28
30 INT106540 Negative_regulation of Phosphorylation of Grin1 15 0.58 9.32 29.13
31 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
32 INT93033 Negative_regulation of Grin2b 48 0.58 20.94 28.54
33 INT80470 Negative_regulation of Gene_expression of Grin1 33 0.59 10.22 27.15
34 INT32794 Gene_expression of Grin2d 81 0.68 20.87 26.99
35 INT61664 Regulation of GRIN1 38 0.60 16.45 25.35
36 INT107577 Negative_regulation of Grin2b 32 0.59 12.35 24.88
37 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
38 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
39 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
40 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
41 INT102281 Positive_regulation of Gene_expression of Grin2b 27 0.70 10.38 20.84
42 INT124670 Gene_expression of Grik1 53 0.77 4.83 19.13
43 INT90612 Positive_regulation of Grin2a 33 0.65 15.11 18.84
44 INT50420 Transcription of Grin1 30 0.71 13.21 18.28
45 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
46 INT63928 Negative_regulation of Grin1 51 0.56 11.81 17.57
47 INT16624 Localization of Grin1 38 0.79 8.46 17.15
48 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
49 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92
50 INT92514 Regulation of Grin2b 22 0.50 11.07 16.92
51 INT88356 Negative_regulation of Positive_regulation of Grin1 16 0.58 4.72 16.58
52 INT197210 Positive_regulation of Grik1 24 0.69 3.15 16.24
53 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
54 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
55 INT18513 Binding of GRIN1 32 0.47 9.44 15.08
56 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
57 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
58 INT14647 Positive_regulation of Grin2a 26 0.67 4.69 14.8
59 INT91913 Regulation of GRIN3B 16 0.61 11.48 14.44
60 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
61 INT92513 Regulation of Grin1 26 0.59 9.12 13.94
62 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78
63 INT7342 Positive_regulation of Positive_regulation of Grin1 18 0.50 9.22 13.76
64 INT49538 Binding of Gria1 22 0.47 2.66 13.35
65 INT103996 Negative_regulation of Phosphorylation of Grin2b 11 0.58 7.81 12.85
66 INT119089 Regulation of Phosphorylation of Grin1 17 0.61 3.1 12.82
67 INT103997 Phosphorylation of Grin2a 17 0.64 10.75 12.67
68 INT122117 Negative_regulation of Gene_expression of Grin2b 20 0.59 11.3 12.55
69 INT100799 Negative_regulation of Grin2a 27 0.57 7.33 12.2
70 INT112103 Binding of Grin1 28 0.48 4.21 12.08
71 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
72 INT51625 Regulation of Gene_expression of Grin2a 12 0.60 3.28 11.6
73 INT48883 Negative_regulation of GRIN3B 19 0.54 14.53 11.5
74 INT116347 Positive_regulation of Positive_regulation of GRIN1 12 0.49 3.63 11.44
75 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
76 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
77 INT130475 Positive_regulation of Phosphorylation of Grin2b 8 0.47 11.52 10.96
78 INT79556 Gene_expression of GRIN3B 16 0.77 7.71 10.75
79 INT51626 Transcription of Grin2a 16 0.68 1.65 10.5
80 INT93036 Negative_regulation of Grin2a 23 0.50 7.1 10.32
81 INT64193 Regulation of Grin2a 19 0.54 2.98 10.31
82 INT8072 Localization of Gria1 17 0.75 2.62 10.04
83 INT115614 Binding of Gria2 25 0.43 8.97 9.91
84 INT6065 Localization of GRIN1 15 0.74 3.15 9.81
85 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
86 INT80006 Regulation of Gene_expression of Grin2b 8 0.57 3.75 9.62
87 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
88 INT78769 Regulation of Grin2a 16 0.58 5.22 9.28
89 INT121987 Phosphorylation of Grin1 11 0.80 4.73 8.88
90 INT112104 Binding of Grin2b 21 0.44 6.78 8.16
91 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
92 INT117642 Regulation of Gene_expression of Grin1 18 0.53 7.09 8.08
93 INT135113 Localization of Grin1 18 0.73 3.73 7.69
94 INT48882 Binding of GRIN3B 9 0.46 5.12 7.66
95 INT110705 Positive_regulation of Positive_regulation of Grin1 11 0.69 4.7 7.33
96 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
97 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
98 INT139149 Binding of Gria1 22 0.37 5.71 6.88
99 INT197216 Localization of Grik1 9 0.80 0.39 6.78
100 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
101 INT100926 Positive_regulation of Gene_expression of Grin2a 11 0.63 3.24 6.41
102 INT153959 Phosphorylation of GRIN1 8 0.80 4.07 6.18
103 INT100658 Negative_regulation of Positive_regulation of Grin2b 7 0.41 1.39 6.17
104 INT74593 Transcription of Grin2b 10 0.66 1.21 5.98
105 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
106 INT130472 Negative_regulation of Phosphorylation of Grin2b 4 0.40 4.4 5.78
107 INT67693 Binding of Grin2a 9 0.38 1.74 5.68
108 INT112102 Regulation of Gene_expression of Gria2 14 0.55 5.4 5.55
109 INT57068 Regulation of Gene_expression of Gria2 12 0.36 3.76 5.44
110 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36
111 INT127353 Regulation of Phosphorylation of Grin2b 5 0.45 1.6 5.29
112 INT130478 Localization of Grin2b 11 0.75 2.49 5.28
113 INT208108 Localization of Grin2a 19 0.70 1.5 5.22
114 INT135998 Localization of Gria2 18 0.72 3.14 5.15
115 INT92541 Localization of Grin2b 11 0.75 2.85 5.14
116 INT259167 Negative_regulation of Phosphorylation of Gria2 2 0.34 5.24 5.13
117 INT19549 Binding of Grin2a 12 0.45 1.24 5.09
118 INT85946 Localization of Gria2 10 0.61 1.23 5.09
119 INT26042 Binding of Gria2 20 0.40 4.88 5.04
120 INT135474 Negative_regulation of Gene_expression of Grin2a 7 0.39 6.94 4.89
121 INT111947 Positive_regulation of Gene_expression of Grin2a 7 0.68 1.75 4.84
122 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71
123 INT197219 Positive_regulation of Gene_expression of Grik1 5 0.69 0.83 4.67
124 INT79505 Binding of Grin2b 9 0.36 1.43 4.61
125 INT197230 Regulation of Positive_regulation of Grik1 4 0.45 0 4.42
126 INT93035 Negative_regulation of Transcription of Grin1 6 0.41 2.29 4.39
127 INT111404 Regulation of Positive_regulation of Grin1 5 0.56 2.49 4.31
128 INT170348 Regulation of Gene_expression of Grin2b 8 0.60 2.29 4.25
129 INT112100 Negative_regulation of Gene_expression of Grin2b 6 0.42 3.71 4.24
130 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
131 INT115354 Regulation of Binding of Grin1 2 0.43 1.15 4.08
132 INT88156 Regulation of Gria1 12 0.54 2.5 4.06
133 INT224807 Gene_expression of Gria4 35 0.78 4.63 4.02
134 INT103999 Positive_regulation of Phosphorylation of Grin2a 5 0.38 3.12 3.94
135 INT129990 Positive_regulation of Phosphorylation of Gria1 11 0.61 3.44 3.87
136 INT163500 Transcription of Grin2b 3 0.67 3.63 3.8
137 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77
138 INT113770 Phosphorylation of Grid1 4 0.14 0.2 3.75
139 INT139646 Positive_regulation of Positive_regulation of Grin2b 4 0.42 3.89 3.74
140 INT84593 Positive_regulation of Binding of Grin1 6 0.48 2.74 3.72
141 INT121986 Phosphorylation of Grin2a 5 0.76 0.83 3.71
142 INT131969 Regulation of Grik1 6 0.61 0.57 3.69
143 INT197207 Negative_regulation of Grik1 5 0.43 1.91 3.5
144 INT209221 Regulation of Gene_expression of Grin2a 5 0.24 2.81 3.45
145 INT132888 Negative_regulation of Phosphorylation of Grin1 3 0.57 1.18 3.43
146 INT231293 Negative_regulation of Grin2d 4 0.45 3.95 3.38
147 INT102276 Gene_expression of Grin2d 10 0.71 4.74 3.37
148 INT84564 Regulation of Positive_regulation of Gria1 2 0.33 1.86 3.3
149 INT51427 Positive_regulation of Positive_regulation of Gria1 11 0.45 1.33 3.28
150 INT170351 Positive_regulation of Gene_expression of Gria2 13 0.67 3.67 3.27
151 INT80007 Transcription of GRIN1 5 0.67 2.36 3.26
152 INT170343 Positive_regulation of Gene_expression of Gria1 10 0.61 2.77 3.09
153 INT132887 Positive_regulation of Phosphorylation of Grin1 3 0.49 1.73 3.08
154 INT90611 Positive_regulation of Positive_regulation of Grin2a 4 0.63 1.89 3
155 INT132243 Gene_expression of Grik4 5 0.58 1.86 2.98
156 INT76715 Gene_expression of Gria3 16 0.75 1.89 2.77
157 INT131973 Positive_regulation of Transcription of Gria1 3 0.49 0.35 2.62
158 INT114513 Negative_regulation of Gene_expression of Gria2 8 0.48 0.89 2.61
159 INT101401 Positive_regulation of Transcription of Grin1 6 0.67 2.45 2.6
160 INT105730 Localization of Grin2a 7 0.67 0.64 2.56
161 INT139148 Negative_regulation of Gene_expression of Gria1 6 0.51 0.89 2.56
162 INT311515 Negative_regulation of Gene_expression of Grin2d 1 0.02 4.37 2.56
163 INT170350 Localization of Gria1 7 0.65 2.36 2.51
164 INT68270 Regulation of Positive_regulation of GRIN1 2 0.44 0.34 2.51
165 INT231295 Positive_regulation of Grin2d 8 0.41 0.7 2.48
166 INT141075 Transcription of Grin2a 5 0.49 1.89 2.46
167 INT114026 Transcription of Grin1 7 0.67 3.13 2.45
168 INT153733 Negative_regulation of Transcription of Gria2 1 0.47 0 2.39
169 INT114024 Positive_regulation of Transcription of Grin1 1 0.49 1.69 2.37
170 INT231297 Localization of Grin2d 8 0.71 1.25 2.36
171 INT311514 Positive_regulation of Gene_expression of Grin2d 8 0.35 2.89 2.26
172 INT113769 Positive_regulation of Phosphorylation of Grid1 3 0.09 0.29 2.21
173 INT82587 Positive_regulation of Gene_expression of GRIN1 8 0.67 3.66 2.18
174 INT281073 Negative_regulation of Gene_expression of Gria2 4 0.56 0.72 2.18
175 INT209594 Positive_regulation of Positive_regulation of GRIN3B 4 0.05 1.06 2.17
176 INT101229 Positive_regulation of Positive_regulation of Gria2 5 0.41 2.2 2.16
177 INT138095 Gene_expression of Grin2c 3 0.63 0.36 2.03
178 INT126500 Regulation of Gene_expression of GRIN1 2 0.44 0.12 2.01
179 INT246518 Regulation of Negative_regulation of Grin2b 1 0.38 0.07 1.99
180 INT151942 Regulation of Negative_regulation of Grin2b 2 0.41 0.41 1.92
181 INT74595 Regulation of Transcription of Grin2a 2 0.42 0.66 1.92
182 INT166340 Transcription of GRIN3B 1 0.72 0.46 1.92
183 INT259164 Positive_regulation of Binding of Gria2 4 0.40 2 1.91
184 INT235114 Localization of GRIN3B 1 0.06 2.41 1.91
185 INT103624 Negative_regulation of Gene_expression of Grin2a 5 0.56 1.58 1.9
186 INT22021 Positive_regulation of Negative_regulation of Grin1 3 0.49 0.69 1.89
187 INT143277 Regulation of Phosphorylation of Gria2 5 0.60 1.91 1.87
188 INT111405 Negative_regulation of Regulation of Grin1 1 0.54 0.09 1.81
189 INT151174 Negative_regulation of Transcription of Grin2a 3 0.40 0 1.8
190 INT74594 Regulation of Transcription of Grin2b 1 0.42 0.17 1.8
191 INT197209 Positive_regulation of Positive_regulation of Grik1 4 0.50 0.36 1.74
192 INT166339 Positive_regulation of Gene_expression of GRIN3B 2 0.47 0.86 1.72
193 INT138660 Positive_regulation of Regulation of Grin1 2 0.24 1.59 1.71
194 INT124667 Negative_regulation of Grik2 4 0.41 2.06 1.7
195 INT218827 Negative_regulation of Phosphorylation of Gria1 6 0.36 3.61 1.67
196 INT103625 Gene_expression of Grin3a 4 0.64 5 1.67
197 INT114508 Positive_regulation of Negative_regulation of Gria2 2 0.36 0.98 1.64
198 INT55709 Negative_regulation of Gria4 7 0.51 1.28 1.6
199 INT135112 Regulation of Phosphorylation of Grin1 2 0.44 0.3 1.58
200 INT71316 Localization of Grik4 3 0.15 0.11 1.55
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