GO:0004982

From wiki-pain
Jump to: navigation, search
Name N-formyl peptide receptor activity
Categary Function
Go Slim No
Go Link GO:0004982
Unique Molecular Interactions 60
Total Molecular Interactions 97
Total Single Events 332
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for N-formyl peptide receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for N-formyl peptide receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT264950 Binding of FPR1 and BOC 1 0.11 0.67 1.55
2 INT318491 IRF6 Positive_regulation of FPR2 1 0.10 6.14 1.44
3 INT45665 Fpr1 Negative_regulation of Mme 1 0.13 0 1
4 INT45664 Fpr1 Negative_regulation of Penk 1 0.13 0 0.99
5 INT126766 Binding of PTGDS and PTGDR2 4 0.40 1.62 0.93
6 INT13193 FPR1 Positive_regulation of ELANE 3 0.44 1.22 0.92
7 INT228054 Fpr3 Positive_regulation of Il10 1 0.05 0.9 0.79
8 INT155610 FPR1 Positive_regulation of Phosphorylation of SGSM3 1 0.04 0.68 0.71
9 INT264943 Negative_regulation of Binding of FPR1 and BOC 1 0.13 0.22 0.64
10 INT264946 Binding of FPR1 and GOPC 1 0.08 0.21 0.64
11 INT45663 Fpr1 Positive_regulation of Penk 1 0.15 0 0.63
12 INT318481 IRF6 Positive_regulation of Gene_expression of FPR2 1 0.14 5.09 0.59
13 INT318487 Negative_regulation of IRF6 Positive_regulation of FPR2 1 0.09 1.39 0.59
14 INT318488 LTB4R Regulation of FPR2 1 0.01 1.07 0.58
15 INT191762 FPR1 Positive_regulation of Gene_expression of IGKV1D-39 1 0.01 0.84 0.56
16 INT167194 FPR1 Positive_regulation of Gene_expression of ITGAM 1 0.52 0.8 0.53
17 INT13191 FPR1 Positive_regulation of Localization of GUSB 1 0.31 0 0.53
18 INT327999 Binding of FPR2 and FPR3 1 0.02 3.72 0.53
19 INT13192 FPR1 Positive_regulation of Localization of LRBA 1 0.47 0 0.53
20 INT263976 Binding of CSF2 and FPR2 1 0.07 0.81 0.51
21 INT263973 Binding of CSF2 and FPR1 1 0.08 0.81 0.51
22 INT14992 FPR1 Positive_regulation of Localization of MPO 2 0.56 1.1 0.49
23 INT14993 MET Positive_regulation of Localization of FPR1 1 0.50 0.44 0.49
24 INT264948 BOC Negative_regulation of FPR1 1 0.13 0.18 0.48
25 INT264949 BOC Negative_regulation of Localization of FPR1 1 0.13 0.18 0.48
26 INT253475 Ncapg2 Positive_regulation of Gene_expression of Fpr3 1 0.21 3.11 0.47
27 INT12702 Regulation of Binding of FPR1 and GUSB 1 0.43 0.18 0.44
28 INT56631 Negative_regulation of FPR1 Positive_regulation of ELANE 1 0.38 0.54 0.44
29 INT264945 GOPC Positive_regulation of Positive_regulation of FPR1 1 0.10 0.2 0.44
30 INT167154 FPR1 Positive_regulation of ING1 1 0.18 0.18 0.44
31 INT12703 Binding of FPR1 and GUSB 1 0.36 0.18 0.44
32 INT72346 FPR1 Regulation of Localization of SFTPA1 1 0.02 0.24 0.42
33 INT318483 Binding of LTB4R and FPR2 1 0.02 0.98 0.42
34 INT318489 Positive_regulation of IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38
35 INT318482 IRF6 Negative_regulation of Gene_expression of FPR2 1 0.09 1.18 0.38
36 INT126767 Positive_regulation of Binding of PTGDS and PTGDR2 1 0.54 0.3 0.35
37 INT167156 FPR1 Positive_regulation of MAPK1 1 0.18 0.09 0.35
38 INT318486 IRF6 Positive_regulation of Negative_regulation of FPR2 1 0.10 1.39 0.35
39 INT167155 FPR1 Positive_regulation of Phosphorylation of MAPK1 1 0.18 0.17 0.33
40 INT270274 Binding of RLN1 and RXFP3 1 0.23 0 0.32
41 INT20403 FPR1 Positive_regulation of Itgax 1 0.02 0.22 0.22
42 INT20392 FPR1 Positive_regulation of CR1 1 0.04 0.22 0.22
43 INT253485 Fpr3 Regulation of Gene_expression of Ptger2 1 0.10 2.87 0.17
44 INT34484 FPR1 Positive_regulation of Localization of MMP2 1 0.36 0.15 0.15
45 INT253467 H37 Positive_regulation of Fpr3 1 0.00 1.27 0.13
46 INT253486 H37 Positive_regulation of Gene_expression of Fpr3 1 0.00 1.17 0.13
47 INT335460 FPR1 Positive_regulation of PIK3CD 1 0.17 0 0.13
48 INT253476 Ptger2 Negative_regulation of Fpr3 1 0.14 1.22 0.12
49 INT253487 Ncapg2 Positive_regulation of Fpr3 1 0.21 0.73 0.08
50 INT20393 Negative_regulation of FPR1 Positive_regulation of CR1 1 0.03 0.07 0.07
51 INT20404 Negative_regulation of FPR1 Positive_regulation of Itgax 1 0.02 0.07 0.07
52 INT253470 Fpr3 Regulation of Positive_regulation of Ncapg2 1 0.11 1.57 0.04
53 INT318479 Positive_regulation of IRF6 Positive_regulation of FPR2 1 0.10 0.94 0.03
54 INT191761 FPR1 Regulation of Localization of MPO 1 0.02 0.52 0.03
55 INT253479 Binding of Ncapg2 and Positive_regulation of Positive_regulation of Fpr3 1 0.23 1.03 0
56 INT256605 FPR1 Positive_regulation of MTOR 1 0.01 2.18 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for N-formyl peptide receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in N-formyl peptide receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14997 Positive_regulation of FPR1 21 0.66 9.82 13.2
2 INT6651 Localization of FPR1 18 0.73 3.27 9.9
3 INT15991 Gene_expression of FPR1 27 0.59 8.22 9.01
4 INT12463 Binding of FPR1 21 0.48 3.16 7.98
5 INT6652 Negative_regulation of FPR1 11 0.42 5.29 7.41
6 INT142949 Gene_expression of FPR2 27 0.71 26.17 5.58
7 INT12707 Negative_regulation of Binding of FPR1 9 0.59 1.45 3.72
8 INT156599 Positive_regulation of FPR2 6 0.64 11.04 3.26
9 INT228043 Gene_expression of Fpr3 3 0.51 33.57 2.78
10 INT318497 Negative_regulation of FPR2 1 0.54 10.69 2.48
11 INT15993 Regulation of FPR1 8 0.40 1.24 2.42
12 INT91442 Binding of PTGDR2 6 0.46 1.5 2.2
13 INT80191 Gene_expression of PTGDR2 9 0.74 4.15 2.11
14 INT100009 Phosphorylation of FPR1 3 0.38 1.02 1.9
15 INT33148 Regulation of FPR2 4 0.25 2.95 1.68
16 INT264966 Positive_regulation of Localization of FPR1 1 0.29 0.62 1.61
17 INT14998 Negative_regulation of Localization of FPR1 3 0.42 1.47 1.38
18 INT12704 Regulation of Binding of FPR1 3 0.23 0.45 1.34
19 INT43987 Phosphorylation of Fpr1 2 0.28 0 1.26
20 INT23922 Positive_regulation of Positive_regulation of FPR1 2 0.44 1.58 1.15
21 INT318505 Negative_regulation of Gene_expression of FPR2 1 0.54 6.55 1.06
22 INT106504 Positive_regulation of PTGDR2 5 0.49 1.32 1.04
23 INT264974 Positive_regulation of Negative_regulation of FPR1 1 0.27 0.1 1.02
24 INT318501 Positive_regulation of Positive_regulation of FPR2 1 0.46 3.21 1.02
25 INT228045 Positive_regulation of Fpr3 2 0.32 6.96 0.94
26 INT228037 Negative_regulation of Fpr3 2 0.20 1.58 0.93
27 INT38092 Localization of Fpr1 1 0.02 0 0.88
28 INT100010 Negative_regulation of Phosphorylation of FPR1 2 0.20 0.25 0.82
29 INT318496 Negative_regulation of Positive_regulation of FPR2 1 0.39 1.39 0.59
30 INT2292 Protein_catabolism of FPR1 1 0.01 0 0.58
31 INT253460 Negative_regulation of Gene_expression of Fpr3 1 0.27 7.01 0.56
32 INT16852 Gene_expression of Fpr1 2 0.60 0.39 0.53
33 INT14995 Negative_regulation of Positive_regulation of FPR1 2 0.41 0.44 0.5
34 INT94066 Binding of Fpr1 1 0.26 0 0.49
35 INT94065 Positive_regulation of Fpr1 1 0.35 0 0.49
36 INT318494 Positive_regulation of Gene_expression of FPR2 1 0.64 7.32 0.48
37 INT32703 Negative_regulation of Fpr1 1 0.59 0 0.44
38 INT167163 Positive_regulation of Phosphorylation of FPR1 1 0.22 0.1 0.4
39 INT35194 Binding of FPR2 3 0.34 0.53 0.39
40 INT256615 Positive_regulation of Gene_expression of FPR1 4 0.29 1.27 0.32
41 INT59871 Negative_regulation of Gene_expression of FPR1 2 0.22 0.88 0.23
42 INT35191 Localization of FPR2 2 0.60 0.23 0.22
43 INT253447 Regulation of Fpr3 1 0.21 1.26 0.22
44 INT209751 Regulation of FPR3 1 0.08 0.56 0.22
45 INT132961 Negative_regulation of PTGDR2 1 0.56 0 0.21
46 INT126773 Negative_regulation of Gene_expression of PTGDR2 1 0.37 0.05 0.18
47 INT180524 Regulation of Gene_expression of FPR1 2 0.20 0.45 0.17
48 INT253449 Regulation of Gene_expression of Fpr3 1 0.18 1.32 0.15
49 INT318495 Positive_regulation of Binding of FPR2 1 0.46 0.2 0.14
50 INT253438 Binding of Fpr3 1 0.17 1 0.13
51 INT253450 Positive_regulation of Binding of Fpr3 1 0.23 1 0.13
52 INT253451 Localization of Fpr3 1 0.34 1.03 0.13
53 INT253456 Positive_regulation of Gene_expression of Fpr3 1 0.21 3.82 0.08
54 INT284510 Transcription of FPR1 2 0.45 0 0
55 INT332497 Regulation of Transcription of FPR1 1 0.29 0 0
56 INT156598 Positive_regulation of FPR3 1 0.47 0 0
57 INT311857 Positive_regulation of Gene_expression of PTGDR2 1 0.06 0.7 0
58 INT253443 Positive_regulation of Positive_regulation of Fpr3 1 0.21 1.02 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox