GO:0004983

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Name neuropeptide Y receptor activity
Categary Function
Go Slim No
Go Link GO:0004983
Unique Molecular Interactions 124
Total Molecular Interactions 171
Total Single Events 1677
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neuropeptide Y receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for neuropeptide Y receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT136525 Binding of Prokr1 and Trpv1 1 0.39 2.9 3.76
2 INT130284 Ins1 Negative_regulation of Gene_expression of Npy 1 0.32 0.1 2.47
3 INT91860 Npy Regulation of Npy1r 2 0.28 1.13 2.24
4 INT139640 Jun Regulation of Gene_expression of Npy 1 0.21 1.98 1.75
5 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
6 INT160304 Npy Regulation of Gene_expression of Fos 3 0.67 1.43 1.68
7 INT7796 Akr1d1 Regulation of Npy 1 0.03 0 1.57
8 INT29127 Npy Positive_regulation of LH 1 0.47 0 1.45
9 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
10 INT73377 Npy Regulation of Adarb1 2 0.03 0.15 1.38
11 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
12 INT142661 Binding of IFIT1 and NPY2R 1 0.00 2.49 1.08
13 INT85718 pcp Regulation of Npy 1 0.03 0 1.07
14 INT139636 Jun Negative_regulation of Phosphorylation of Npy 1 0.33 1.07 1.01
15 INT139643 Jun Negative_regulation of Positive_regulation of Npy 1 0.33 1.07 1
16 INT139642 Positive_regulation of Jun Regulation of Gene_expression of Npy 1 0.21 1.07 0.97
17 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96
18 INT116185 Npy Negative_regulation of Positive_regulation of Npy1r 1 0.41 0.32 0.96
19 INT139638 Positive_regulation of Jun Positive_regulation of Positive_regulation of Npy 1 0.36 1.18 0.96
20 INT130282 Cyp3a23/3a1 Positive_regulation of Gene_expression of Npy 1 0.15 0 0.94
21 INT9014 Binding of Npy and Penk 1 0.37 0 0.93
22 INT7794 Ptgdr Regulation of Npy 1 0.11 0 0.92
23 INT162875 Binding of Npvf and Qrfpr 1 0.35 0.49 0.91
24 INT199393 Prok2 Positive_regulation of Prokr1 1 0.48 1.3 0.9
25 INT137563 Ghrl Positive_regulation of Gene_expression of Npy 1 0.59 0 0.87
26 INT199391 Pklr Positive_regulation of Prokr1 1 0.31 1.28 0.87
27 INT66333 Fgf2 Negative_regulation of Positive_regulation of Npy 1 0.20 0.17 0.85
28 INT48751 Binding of Nqo1 and Npy 1 0.28 0 0.82
29 INT157297 Npy Regulation of Npy1r 1 0.18 0.19 0.82
30 INT128943 Pomc Regulation of Npy 1 0.23 0.61 0.81
31 INT130281 Dexi Positive_regulation of Gene_expression of Npy 1 0.08 0 0.79
32 INT130283 Cyp3a23/3a1 Positive_regulation of Transcription of Npy 1 0.10 0 0.79
33 INT130285 Dexi Positive_regulation of Transcription of Npy 1 0.07 0 0.79
34 INT29128 Negative_regulation of Npy Positive_regulation of LH 1 0.44 0 0.77
35 INT215630 Fig4 Regulation of Npy 1 0.01 0.26 0.76
36 INT133675 NPY6R Negative_regulation of SRC 1 0.17 0.75 0.74
37 INT13344 Binding of Npy and Adarb1 2 0.02 0.41 0.73
38 INT14621 Gal Regulation of Npy 1 0.30 0 0.7
39 INT12759 Npy Regulation of Localization of Calca 1 0.26 0.08 0.68
40 INT199394 Prok2 Regulation of Positive_regulation of Prokr1 1 0.28 0.89 0.68
41 INT199390 Pklr Regulation of Positive_regulation of Prokr1 1 0.18 0.89 0.68
42 INT15322 Binding of Npy and Cck 1 0.26 0.45 0.66
43 INT7792 Akr1d1 Regulation of Gene_expression of Npy 1 0.02 0 0.65
44 INT73381 Npy5r Positive_regulation of Positive_regulation of Npy 1 0.12 0 0.63
45 INT147891 Prokr1 Positive_regulation of Localization of Abat 1 0.05 0.36 0.6
46 INT95895 Sigmar1 Regulation of Positive_regulation of Npy 1 0.18 0 0.55
47 INT160061 Positive_regulation of Syt17 Positive_regulation of Localization of Npy 1 0.09 0 0.51
48 INT66336 Fgf2 Regulation of Gene_expression of Npy 1 0.12 0.09 0.5
49 INT160062 Syt17 Positive_regulation of Localization of Npy 1 0.09 0 0.5
50 INT21315 AGT Positive_regulation of Npy 1 0.03 0.15 0.5
51 INT71318 Grik4 Positive_regulation of Localization of Npy 1 0.05 0 0.47
52 INT71317 Grip2 Positive_regulation of Localization of Npy 1 0.09 0 0.47
53 INT26448 Adra2a Regulation of Positive_regulation of Npy 1 0.06 0 0.46
54 INT172247 Binding of NCOR2 and QRFPR 1 0.01 0.12 0.43
55 INT12498 Pyy Positive_regulation of Npy 1 0.39 0 0.43
56 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41
57 INT59742 Glp1r Positive_regulation of Gene_expression of Npy 1 0.27 0.32 0.41
58 INT59740 Glp1r Positive_regulation of Localization of Npy 1 0.25 0.33 0.41
59 INT59739 Glp1r Positive_regulation of Transcription of Npy 1 0.25 0.32 0.41
60 INT190977 Npy Regulation of Scn2a1 1 0.16 0 0.4
61 INT151633 Binding of Npy and Tacr1 1 0.16 0.39 0.4
62 INT58958 Npy Negative_regulation of LH 1 0.47 0 0.38
63 INT70656 Adra2a Regulation of Gene_expression of Npy 1 0.23 0 0.38
64 INT177396 Npy1r Positive_regulation of Negative_regulation of Npy 1 0.27 0.38 0.37
65 INT144345 Binding of Qrfpr and Qrfp 1 0.40 0 0.34
66 INT23882 Npy Positive_regulation of Bcar1 1 0.34 0.67 0.34
67 INT26196 Npy Positive_regulation of Localization of Crh 1 0.40 0 0.33
68 INT137561 Ghrl Regulation of Gene_expression of Npy 1 0.53 0 0.32
69 INT59326 Binding of Adra1a and Positive_regulation of Binding of Npy 1 0.44 0 0.31
70 INT17351 Npy Regulation of Trh 1 0.46 0 0.28
71 INT7668 Npy1r Regulation of Sstr4 1 0.07 0.77 0.26
72 INT106658 Adcyap1 Positive_regulation of Gene_expression of Npy 1 0.54 0.16 0.25
73 INT215652 Binding of Adora1 and Npy1r 1 0.39 0.22 0.24
74 INT177398 Binding of Npy1r and Npy 1 0.18 0.73 0.24
75 INT177397 Binding of Npy5r and Npy 1 0.16 0.73 0.24
76 INT137278 Positive_regulation of Penk Regulation of Npy 1 0.41 0 0.23
77 INT137279 Penk Regulation of Npy 1 0.24 0 0.23
78 INT71843 Npy Regulation of Vip 1 0.29 0 0.22
79 INT139902 Kcne2 Positive_regulation of Gpr83 1 0.03 1.43 0.22
80 INT139903 Ins1 Positive_regulation of Gpr83 1 0.13 1.43 0.22
81 INT8091 Npy Regulation of Localization of LH 2 0.27 0 0.21
82 INT59741 Faah Positive_regulation of Localization of Npy 1 0.01 0.16 0.21
83 INT78263 Npy Positive_regulation of Npy2r 1 0.04 0 0.21
84 INT25720 Npy Negative_regulation of Avp 1 0.48 0.1 0.21
85 INT25721 Negative_regulation of Npy Negative_regulation of Avp 1 0.48 0.1 0.21
86 INT233507 Tlr4 Regulation of Prokr1 1 0.04 0.48 0.2
87 INT72352 Npy Positive_regulation of Npy1r 1 0.09 0.15 0.2
88 INT59745 Faah Positive_regulation of Gene_expression of Npy 1 0.01 0.16 0.2
89 INT59743 Faah Positive_regulation of Transcription of Npy 1 0.01 0.16 0.2
90 INT95896 Npy Positive_regulation of Positive_regulation of Gtpbp4 1 0.12 0 0.2
91 INT50742 Npy Positive_regulation of Gene_expression of Gnrh1 1 0.37 0 0.19
92 INT59589 Npy Regulation of Crh 1 0.27 0 0.18
93 INT59588 Npy Positive_regulation of Crh 1 0.41 0 0.18
94 INT59587 Npy Regulation of Gene_expression of Crh 1 0.27 0 0.18
95 INT8093 Npy Negative_regulation of Localization of Gnrh1 1 0.47 0 0.16
96 INT59508 Binding of Npy5r and Pyy 1 0.00 0.08 0.12
97 INT272439 Binding of ARAF and Prokr2 1 0.01 0.59 0.09
98 INT8092 Npy Regulation of Localization of Gnrh1 2 0.30 0.08 0.08
99 INT294308 PROKR1 Regulation of Gene_expression of IL11 1 0.34 0 0.08
100 INT294315 PROK1 Regulation of PROKR1 1 0.24 0 0.08
101 INT233522 Tlr4 Positive_regulation of Gene_expression of Prokr1 1 0.08 0.44 0.07
102 INT233521 Binding of Pklr and Prokr1 1 0.17 0.44 0.07
103 INT317245 Binding of Npy2r and Pyy 1 0.09 0 0.05
104 INT233514 Tlr4 Positive_regulation of Prokr1 1 0.10 0.45 0.05
105 INT172235 Binding of NPY and PROKR1 1 0.19 0 0.05
106 INT317246 Binding of Npy2r and Npy 1 0.08 0 0.05
107 INT172249 Binding of NPY and GPR83 1 0.23 0 0.04
108 INT275751 xn Positive_regulation of Gpr83 1 0.02 0.24 0.03
109 INT294312 PROKR1 Positive_regulation of Gene_expression of IL11 1 0.38 0 0
110 INT306017 Binding of Gpr83 and Tlr4 1 0.08 0.58 0
111 INT222541 Npy Positive_regulation of Localization of Prl 1 0.07 0 0
112 INT198019 NPY6R Negative_regulation of Gene_expression of SRC 1 0.06 1.75 0
113 INT149996 Npy6r Negative_regulation of Csk 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neuropeptide Y receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in neuropeptide Y receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21
2 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2
3 INT6107 Localization of Npy 180 0.81 26.76 81.67
4 INT5338 Regulation of Npy 92 0.62 25.54 51.24
5 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75
6 INT17925 Transcription of Npy 53 0.72 15.75 25.56
7 INT12424 Binding of Npy 48 0.48 8.23 24.26
8 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13
9 INT7667 Regulation of Gene_expression of Npy 28 0.60 16.65 16.11
10 INT49147 Gene_expression of Npy1r 27 0.76 6.57 14.75
11 INT12281 Negative_regulation of Gene_expression of Npy 23 0.59 7.45 13.41
12 INT8086 Negative_regulation of Localization of Npy 24 0.59 3.31 12.76
13 INT23254 Positive_regulation of Localization of Npy 27 0.65 3.01 11.98
14 INT135578 Gene_expression of Prokr1 22 0.70 11.71 8.31
15 INT5340 Negative_regulation of Positive_regulation of Npy 12 0.55 3.83 8.23
16 INT5339 Positive_regulation of Positive_regulation of Npy 13 0.68 4.5 8.15
17 INT8087 Regulation of Localization of Npy 16 0.45 2.41 6.81
18 INT7665 Negative_regulation of Npy1r 10 0.45 2.87 6.73
19 INT72350 Positive_regulation of Npy1r 15 0.63 6.28 6.55
20 INT53773 Positive_regulation of Transcription of Npy 11 0.70 3.75 6.29
21 INT51239 Negative_regulation of Transcription of Npy 9 0.57 2.85 5.87
22 INT199383 Gene_expression of Prokr2 8 0.59 7.37 5.21
23 INT18371 Regulation of Positive_regulation of Npy 8 0.60 2.49 4.38
24 INT47894 Regulation of Npy1r 5 0.33 3.08 4.27
25 INT116181 Localization of Npy1r 10 0.79 2.17 3.94
26 INT168736 Binding of Npy1r 4 0.35 0.24 3.89
27 INT76373 Positive_regulation of Gene_expression of Npy1r 6 0.38 1.84 3.64
28 INT24337 Positive_regulation of Regulation of Npy 5 0.50 2.8 3.4
29 INT72349 Transcription of Npy1r 3 0.41 1.76 2.93
30 INT78253 Gene_expression of Npy2r 7 0.77 1.49 2.89
31 INT77325 Regulation of Gene_expression of Npy1r 5 0.41 1.62 2.89
32 INT136522 Negative_regulation of Prokr1 9 0.58 3.53 2.71
33 INT21313 Negative_regulation of Binding of Npy 5 0.42 0.39 2.49
34 INT8666 Regulation of Regulation of Npy 3 0.21 0 2.4
35 INT57664 Gene_expression of Npy2r 4 0.19 1.41 2.26
36 INT63440 Regulation of Transcription of Npy 5 0.39 1.53 2.25
37 INT233649 Gene_expression of Npy5r 1 0.57 0.6 1.69
38 INT134617 Gene_expression of Npy1r 2 0.57 1.3 1.63
39 INT161667 Positive_regulation of Prokr1 7 0.42 2.73 1.59
40 INT7897 Positive_regulation of Negative_regulation of Npy 4 0.47 1.1 1.55
41 INT75871 Negative_regulation of Positive_regulation of Npy1r 2 0.53 1.34 1.51
42 INT77322 Negative_regulation of Transcription of Npy1r 1 0.33 0.86 1.51
43 INT136523 Binding of Prokr1 2 0.48 0.85 1.47
44 INT66527 Positive_regulation of Npy2r 2 0.31 0.47 1.44
45 INT144341 Binding of Qrfpr 4 0.36 0.89 1.4
46 INT135577 Transcription of Prokr1 2 0.43 0.59 1.32
47 INT144342 Transcription of Qrfpr 4 0.69 0.25 1.27
48 INT120576 Negative_regulation of Negative_regulation of Npy1r 1 0.20 0.29 1.2
49 INT122474 Negative_regulation of Npy1r 3 0.42 1.71 1.1
50 INT144340 Gene_expression of Qrfpr 3 0.67 1.85 1.05
51 INT7895 Negative_regulation of Negative_regulation of Npy 3 0.43 0.34 1.03
52 INT133678 Negative_regulation of NPY6R 2 0.20 0.74 1
53 INT177392 Binding of Npy1r 2 0.47 1.14 0.98
54 INT139634 Phosphorylation of Npy 1 0.68 1.03 0.98
55 INT134618 Regulation of Gene_expression of Npy1r 1 0.38 1.03 0.97
56 INT66526 Regulation of Positive_regulation of Npy2r 1 0.20 0 0.96
57 INT116179 Negative_regulation of Localization of Npy1r 1 0.38 0.32 0.96
58 INT80315 Binding of Npy2r 2 0.48 0.53 0.95
59 INT116180 Positive_regulation of Localization of Npy1r 1 0.45 0.32 0.95
60 INT31813 Positive_regulation of Gpr83 3 0.61 0 0.92
61 INT193666 Gene_expression of Gpr83 2 0.14 0.92 0.91
62 INT209970 Negative_regulation of Gpr83 1 0.08 0.69 0.91
63 INT105370 Binding of Npy5r 2 0.00 0.33 0.9
64 INT31812 Gene_expression of Gpr83 3 0.78 0 0.87
65 INT77324 Negative_regulation of Gene_expression of Npy1r 3 0.42 0.45 0.85
66 INT80316 Positive_regulation of Npy2r 3 0.31 0.28 0.78
67 INT80464 Regulation of Npy5r 1 0.08 0.79 0.71
68 INT128728 Localization of Npy2r 3 0.80 0 0.65
69 INT236000 Gene_expression of NPY6R 1 0.09 0 0.65
70 INT78255 Transcription of Npy2r 1 0.12 0.59 0.62
71 INT120997 Regulation of Npy5r 1 0.00 0.54 0.6
72 INT77323 Regulation of Transcription of Npy1r 1 0.21 0.39 0.59
73 INT80317 Positive_regulation of Binding of Npy2r 1 0.16 0.34 0.56
74 INT209971 Positive_regulation of Gpr83 4 0.40 1.28 0.55
75 INT142663 Binding of NPY2R 1 0.01 1.24 0.54
76 INT80466 Gene_expression of Npy5r 2 0.39 0.82 0.52
77 INT55360 Positive_regulation of Npy5r 2 0.37 0 0.5
78 INT253066 Positive_regulation of Gene_expression of Prokr1 1 0.26 0.58 0.48
79 INT81322 Negative_regulation of GPR83 2 0.42 0.83 0.46
80 INT209968 Positive_regulation of Gene_expression of Gpr83 1 0.06 0.16 0.44
81 INT116178 Positive_regulation of Positive_regulation of Npy1r 1 0.45 0.1 0.43
82 INT236002 Negative_regulation of Gene_expression of NPY6R 1 0.05 0 0.42
83 INT177395 Negative_regulation of Binding of Npy1r 1 0.37 0.62 0.41
84 INT59325 Positive_regulation of Binding of Npy 1 0.45 0 0.35
85 INT252472 Phosphorylation of Npy6r 1 0.05 0 0.34
86 INT273601 Positive_regulation of Localization of GPR83 1 0.15 1.85 0.31
87 INT89843 Phosphorylation of Npy5r 1 0.00 0 0.27
88 INT122473 Positive_regulation of Npy1r 1 0.40 0.66 0.26
89 INT111046 Regulation of Npy1r 1 0.31 0.27 0.25
90 INT215603 Localization of Npy1r 1 0.73 0.24 0.24
91 INT250409 Positive_regulation of Npy5r 1 0.03 0 0.24
92 INT64107 Negative_regulation of Npy2r 1 0.12 0 0.2
93 INT209975 Binding of Gpr83 2 0.08 0.5 0.19
94 INT209972 Regulation of Binding of Gpr83 2 0.10 0.36 0.19
95 INT201127 Positive_regulation of QRFPR 1 0.21 0.59 0.18
96 INT209974 Regulation of Gpr83 3 0.07 0.29 0.17
97 INT272420 Positive_regulation of Prokr2 1 0.18 1.02 0.17
98 INT294320 Positive_regulation of PROKR1 2 0.39 0.34 0.15
99 INT78262 Transcription of Npy2r 1 0.07 0 0.15
100 INT273602 Localization of GPR83 1 0.24 0.89 0.15
101 INT78261 Negative_regulation of Npy5r 1 0.30 0 0.15
102 INT201129 Binding of QRFPR 5 0.11 1.09 0.13
103 INT250408 Positive_regulation of Gene_expression of Npy2r 1 0.08 0.09 0.12
104 INT209973 Negative_regulation of Negative_regulation of Gpr83 1 0.05 0.1 0.12
105 INT172277 Binding of PROKR1 1 0.21 0 0.12
106 INT209969 Regulation of Negative_regulation of Gpr83 1 0.05 0.1 0.12
107 INT201132 Gene_expression of QRFPR 1 0.23 1.77 0.11
108 INT253056 Positive_regulation of Transcription of Prokr1 1 0.30 0 0.1
109 INT172296 Binding of GPR83 1 0.35 0 0.09
110 INT201131 Localization of QRFPR 1 0.24 0.9 0.08
111 INT253064 Negative_regulation of Gene_expression of Prokr1 1 0.26 0 0.07
112 INT235312 Negative_regulation of Gpr83 7 0.37 3.75 0.06
113 INT252471 Gene_expression of Npy6r 1 0.05 0 0.06
114 INT253059 Negative_regulation of Transcription of Prokr1 1 0.22 0.06 0.05
115 INT253063 Regulation of Gene_expression of Prokr1 1 0.27 0 0.04
116 INT324984 Positive_regulation of Qrfpr 1 0.06 0.46 0.04
117 INT324988 Regulation of Qrfpr 1 0.05 0.31 0.04
118 INT201128 Regulation of QRFPR 1 0.13 0.2 0.03
119 INT324983 Negative_regulation of Qrfpr 1 0.05 0.29 0
120 INT201133 Positive_regulation of Gene_expression of QRFPR 1 0.15 0.12 0
121 INT324986 Regulation of Binding of Qrfpr 1 0.05 0.16 0
122 INT130559 Negative_regulation of Gene_expression of Npy5r 1 0.22 0 0
123 INT275738 Regulation of Gpr83 1 0.08 0 0
124 INT201126 Positive_regulation of Positive_regulation of QRFPR 1 0.15 0 0
125 INT294349 Gene_expression of PROKR1 1 0.50 0.48 0
126 INT76871 Regulation of Npy2r 1 0.19 0 0
127 INT324985 Localization of Qrfpr 1 0.08 0.48 0
128 INT272419 Regulation of Prokr1 1 0.08 0.29 0
129 INT294357 Localization of PROKR1 1 0.67 0 0
130 INT324987 Negative_regulation of Binding of Qrfpr 1 0.05 0.16 0
131 INT275739 Positive_regulation of Positive_regulation of Gpr83 1 0.08 0 0
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