GO:0004992

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Name platelet activating factor receptor activity
Categary Function
Go Slim No
Go Link GO:0004992
Unique Molecular Interactions 87
Total Molecular Interactions 120
Total Single Events 722
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for platelet activating factor receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for platelet activating factor receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT272144 PTAFR Positive_regulation of HRASLS 1 0.08 1.08 0.89
2 INT121467 Binding of Avp and Ptafr 1 0.11 0.98 0.88
3 INT342986 PTAFR Positive_regulation of Gene_expression of IL6 1 0.14 0.39 0.84
4 INT16014 Ptafr Regulation of Ns5atp9 1 0.32 1.17 0.78
5 INT342992 Negative_regulation of PTAFR Negative_regulation of Gene_expression of HIST2H2AA3 1 0.01 0.4 0.78
6 INT308483 Paf Positive_regulation of Gene_expression of Ptafr 1 0.12 1.14 0.78
7 INT308485 Paf Positive_regulation of Ptafr 1 0.12 1.13 0.77
8 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71
9 INT342981 PTAFR Regulation of SFTPA1 1 0.03 0.38 0.6
10 INT272146 PTAFR Positive_regulation of Localization of IL8 3 0.38 0.28 0.59
11 INT342983 HCL1 Positive_regulation of PTAFR 1 0.03 0.07 0.47
12 INT342987 TRPV1 Positive_regulation of Localization of PTAFR 1 0.33 0.84 0.43
13 INT272148 PTAFR Regulation of Localization of CA2 1 0.14 0 0.38
14 INT337304 PTAFR Positive_regulation of Gene_expression of TLR4 1 0.62 1.99 0.36
15 INT75947 Positive_regulation of Binding of Frk and Ptafr 1 0.11 1.26 0.34
16 INT75954 Negative_regulation of Binding of Frk and Ptafr 1 0.09 1.28 0.34
17 INT75949 Negative_regulation of Binding of Cpe and Ptafr 1 0.03 1.27 0.33
18 INT75953 Binding of Cpe and Ptafr 1 0.03 1.27 0.33
19 INT75945 Binding of Frk and Ptafr 1 0.08 1.25 0.33
20 INT75948 Positive_regulation of Binding of Ptafr and Sst 1 0.23 1.26 0.33
21 INT75951 Binding of Ptafr and Sst 1 0.17 1.26 0.33
22 INT75940 Positive_regulation of Binding of Cpe and Ptafr 1 0.04 1.27 0.33
23 INT75952 Negative_regulation of Binding of Ptafr and Sst 1 0.19 1.27 0.33
24 INT123398 TPSAB1 Positive_regulation of Gene_expression of PTAFR 1 0.14 0.51 0.32
25 INT123397 F2 Positive_regulation of Gene_expression of PTAFR 1 0.05 0.51 0.32
26 INT39317 Binding of ADRA1D and PTAFR 1 0.54 0.54 0.3
27 INT337293 PTAFR Positive_regulation of Positive_regulation of TLR4 1 0.62 1.43 0.28
28 INT10177 Binding of Ptafr and Gtf3a 1 0.02 1.34 0.28
29 INT269313 Binding of Ptafr and Gp6 1 0.00 0.48 0.26
30 INT55901 Negative_regulation of Alox5 Negative_regulation of Localization of Ptafr 1 0.01 0.35 0.24
31 INT55902 Negative_regulation of Pla2g1b Negative_regulation of Localization of Ptafr 1 0.11 0.35 0.24
32 INT102620 PTAFR Regulation of Gene_expression of IL6 1 0.24 0.29 0.24
33 INT102622 PTAFR Regulation of IL6 1 0.24 0.29 0.24
34 INT342997 PTAFR Positive_regulation of Gene_expression of HIST2H2AA3 1 0.01 0.61 0.24
35 INT55903 Negative_regulation of Mthfs Negative_regulation of Localization of Ptafr 1 0.01 0.35 0.24
36 INT102617 PTAFR Regulation of Gene_expression of PTGS2 1 0.12 0.29 0.24
37 INT272143 PTAFR Positive_regulation of Gene_expression of PTGS2 1 0.12 1.59 0.23
38 INT342994 IL1B Positive_regulation of Gene_expression of PTAFR 1 0.09 0.39 0.22
39 INT337295 PTAFR Positive_regulation of Localization of STAT3 1 0.43 0.85 0.22
40 INT272150 Positive_regulation of PTAFR Positive_regulation of HRASLS 1 0.06 0.16 0.21
41 INT39318 Binding of MPG and PTAFR 1 0.54 0.36 0.2
42 INT267629 PTAFR Positive_regulation of Localization of Il1 1 0.00 1.32 0.18
43 INT337310 PTAFR Regulation of Gene_expression of TLR4 1 0.24 0.8 0.18
44 INT73331 PTAFR Positive_regulation of Transcription of PTGS2 1 0.13 0.54 0.18
45 INT26190 PTAFR Regulation of AVP 1 0.16 0 0.14
46 INT272145 Binding of PTAFR and HRASLS 1 0.04 0.06 0.13
47 INT192330 UBR7 Negative_regulation of Positive_regulation of PDGFRB 1 0.01 0.54 0.12
48 INT272149 PTAFR Positive_regulation of Localization of IL6 1 0.24 0 0.12
49 INT345011 Binding of GSN and PTAFR 1 0.09 0.83 0.12
50 INT337308 PTAFR Regulation of TLR4 1 0.24 0.1 0.1
51 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09
52 INT110220 Pla2g2a Positive_regulation of Gene_expression of Ptafr 1 0.11 0.5 0.09
53 INT110219 Pla2g1b Positive_regulation of Gene_expression of Ptafr 1 0.17 0.5 0.09
54 INT244639 AGK Negative_regulation of PDGFRB 1 0.01 0.69 0.08
55 INT337290 PTAFR Positive_regulation of Phosphorylation of STAT3 1 0.43 0.07 0.07
56 INT298006 CHDM Positive_regulation of Gene_expression of PDGFRB 1 0.16 1.08 0.07
57 INT192329 UBR7 Negative_regulation of Phosphorylation of PDGFRB 1 0.01 0.06 0.07
58 INT337302 PLA2G6 Regulation of Gene_expression of PTAFR 1 0.09 1.18 0.07
59 INT337297 PTAFR Positive_regulation of EDNRA 1 0.04 1.2 0.06
60 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06
61 INT337303 Positive_regulation of PTAFR Positive_regulation of EDNRA 1 0.04 1.21 0.06
62 INT279287 PDGFRB Regulation of CDCP1 1 0.01 0.98 0.05
63 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04
64 INT347463 Binding of PTAFR and ST7L 1 0.00 0 0.04
65 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04
66 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03
67 INT337305 PTAFR Regulation of Localization of IL8 1 0.06 0.47 0
68 INT102626 PTAFR Positive_regulation of Gene_expression of CPOX 1 0.11 0.1 0
69 INT337309 PTAFR Regulation of Localization of IRF6 1 0.06 0.89 0
70 INT337292 STAT3 Negative_regulation of Gene_expression of PTAFR 1 0.27 0.3 0
71 INT102618 PTAFR Regulation of Gene_expression of CPOX 1 0.08 0.38 0
72 INT292091 MIR1200 Negative_regulation of PDGFRB 1 0.01 1.24 0
73 INT102624 IL6 Positive_regulation of PTAFR 1 0.21 0.05 0
74 INT165438 PTAFR Positive_regulation of Gene_expression of ITGAM 1 0.45 0 0
75 INT337299 PTAFR Regulation of STAT3 1 0.28 0 0
76 INT279283 TXK Regulation of PDGFRB 1 0.06 0.68 0
77 INT337307 Positive_regulation of PTAFR Positive_regulation of Localization of STAT3 1 0.25 0 0
78 INT295426 Binding of KIT and PDGFRB 1 0.24 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for platelet activating factor receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in platelet activating factor receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58
2 INT5160 Localization of PTAFR 61 0.80 42.6 19.16
3 INT13303 Positive_regulation of PTAFR 40 0.69 16.27 11.56
4 INT30526 Negative_regulation of PTAFR 15 0.58 8.15 8.19
5 INT308473 Positive_regulation of Ptafr 1 0.58 13.26 7.92
6 INT32454 Gene_expression of Ptafr 3 0.65 15.19 7.87
7 INT10505 Gene_expression of Ptafr 18 0.62 10.7 6.83
8 INT10507 Positive_regulation of Gene_expression of PTAFR 15 0.61 10.24 6.61
9 INT48234 Negative_regulation of Gene_expression of PTAFR 11 0.57 3.97 6.25
10 INT308479 Transcription of Ptafr 1 0.60 10.05 4.76
11 INT97847 Regulation of Ptafr 3 0.43 5.41 4.64
12 INT10896 Regulation of PTAFR 16 0.61 4.22 4.5
13 INT54701 Localization of Ptafr 19 0.49 18.68 3.82
14 INT13302 Binding of PTAFR 20 0.48 7.03 3.7
15 INT308474 Positive_regulation of Transcription of Ptafr 1 0.58 7.33 3.66
16 INT32453 Positive_regulation of Gene_expression of Ptafr 2 0.58 7.01 3.47
17 INT79360 Negative_regulation of Ptafr 6 0.36 4.15 2.77
18 INT51683 Regulation of Gene_expression of PTAFR 11 0.60 5.06 2.59
19 INT51680 Protein_catabolism of PTAFR 7 0.64 3.69 2.59
20 INT337317 Positive_regulation of Localization of PTAFR 2 0.51 3.88 2.5
21 INT205683 Localization of Ptafr 4 0.12 4.63 2.31
22 INT308477 Positive_regulation of Positive_regulation of Ptafr 1 0.51 4.3 2.29
23 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2
24 INT55469 Positive_regulation of Positive_regulation of PTAFR 9 0.47 3 2.17
25 INT91519 Negative_regulation of Positive_regulation of PTAFR 4 0.41 1.52 2.15
26 INT7745 Regulation of Ptafr 7 0.40 1.99 2.12
27 INT55070 Binding of Ptafr 5 0.41 3.5 2.07
28 INT55899 Positive_regulation of Ptafr 6 0.63 4.7 1.34
29 INT27911 Negative_regulation of Gene_expression of Ptafr 3 0.37 0.58 1.32
30 INT145550 Phosphorylation of Ptafr 1 0.52 1.03 1.28
31 INT73720 Positive_regulation of Gene_expression of Ptafr 4 0.42 4.15 1.25
32 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72
33 INT19584 Negative_regulation of Ptafr 3 0.56 1.82 0.61
34 INT32452 Binding of Ptafr 5 0.42 2.6 0.58
35 INT64980 Positive_regulation of Localization of Ptafr 2 0.05 2.36 0.54
36 INT308481 Negative_regulation of Transcription of Ptafr 1 0.36 1.37 0.53
37 INT73200 Positive_regulation of PDGFRB 10 0.67 9.67 0.48
38 INT192342 Phosphorylation of PDGFRB 11 0.80 1.68 0.43
39 INT54700 Negative_regulation of Localization of Ptafr 2 0.26 0.98 0.41
40 INT192344 Negative_regulation of Phosphorylation of PDGFRB 4 0.54 1.26 0.38
41 INT192348 Positive_regulation of Gene_expression of PDGFRB 5 0.64 3.57 0.3
42 INT238901 Phosphorylation of PTAFR 2 0.58 1.54 0.3
43 INT279296 Localization of PDGFRB 4 0.54 2.71 0.24
44 INT337320 Negative_regulation of Protein_catabolism of PTAFR 1 0.40 1.66 0.22
45 INT55071 Regulation of Binding of Ptafr 1 0.43 0.65 0.21
46 INT272151 Transcription of PTAFR 1 0.51 1.43 0.21
47 INT13304 Negative_regulation of Binding of PTAFR 1 0.43 0 0.19
48 INT272153 Negative_regulation of Localization of PTAFR 1 0.42 0.08 0.18
49 INT77418 Negative_regulation of Binding of Ptafr 1 0.51 0.45 0.16
50 INT192339 Positive_regulation of Positive_regulation of PDGFRB 2 0.46 1.02 0.14
51 INT69523 Regulation of Localization of PTAFR 2 0.45 0.32 0.12
52 INT39320 Regulation of Regulation of PTAFR 1 0.27 0.25 0.11
53 INT192341 Negative_regulation of Gene_expression of PDGFRB 3 0.40 0.85 0.08
54 INT192338 Positive_regulation of Phosphorylation of PDGFRB 4 0.45 0.48 0.07
55 INT51641 Regulation of Positive_regulation of PTAFR 1 0.45 0 0.07
56 INT337318 Positive_regulation of Regulation of PTAFR 1 0.47 0.06 0.06
57 INT223616 Binding of PDGFRB 3 0.32 2.33 0.05
58 INT192340 Regulation of PDGFRB 4 0.45 3.83 0.03
59 INT279297 Positive_regulation of Localization of PDGFRB 1 0.36 0.5 0.03
60 INT336195 Negative_regulation of Negative_regulation of PDGFRB 1 0.03 0.19 0
61 INT338265 Positive_regulation of Binding of PDGFRB 1 0.25 1.38 0
62 INT328279 Positive_regulation of Regulation of PDGFRB 1 0.37 0.74 0
63 INT200104 Regulation of Gene_expression of PDGFRB 1 0.18 0.29 0
64 INT336019 Positive_regulation of Positive_regulation of Ptafr 1 0.12 0.79 0
65 INT292121 Regulation of Regulation of PDGFRB 1 0.22 0.93 0
66 INT292128 Positive_regulation of Negative_regulation of PDGFRB 1 0.25 1.08 0
67 INT337313 Positive_regulation of Phosphorylation of PTAFR 1 0.43 0.32 0
68 INT328277 Negative_regulation of Positive_regulation of PDGFRB 1 0.36 1.64 0
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