GO:0004999

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Name vasoactive intestinal polypeptide receptor activity
Categary Function
Go Slim No
Go Link GO:0004999
Unique Molecular Interactions 31
Total Molecular Interactions 41
Total Single Events 174
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for vasoactive intestinal polypeptide receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for vasoactive intestinal polypeptide receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT114217 Binding of VIPR1 and Trpv1 1 0.03 0 0.66
2 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56
3 INT187230 Binding of Adcyap1 and Vipr1 1 0.11 0.92 0.38
4 INT187228 Binding of Adcyap1 and Vipr2 1 0.11 0.91 0.38
5 INT190751 Adcyap1 Positive_regulation of Vipr2 2 0.16 1.02 0.36
6 INT190290 Binding of CXCL12 and VIPR1 1 0.06 0 0.33
7 INT113031 Vip Positive_regulation of Vipr2 1 0.77 0 0.29
8 INT233785 Binding of SCT and VIPR1 1 0.08 0 0.27
9 INT233783 Binding of SCT and VIPR2 1 0.13 0 0.27
10 INT273048 Adcyap1 Positive_regulation of Adcyap1r1 1 0.11 1.02 0.19
11 INT187221 Binding of Vip and Vipr1 1 0.20 0.41 0.19
12 INT190749 Adcyap1 Positive_regulation of Vipr1 1 0.11 0 0.17
13 INT190737 Vip Positive_regulation of Vipr1 1 0.03 0 0.17
14 INT190740 Vip Positive_regulation of Vipr2 1 0.03 0 0.17
15 INT349850 Gfra1 Negative_regulation of Adcyap1r1 1 0.15 0.36 0.15
16 INT349851 Gfra3 Negative_regulation of Adcyap1r1 1 0.28 0.31 0.15
17 INT349849 Gfra2 Negative_regulation of Adcyap1r1 1 0.33 0.31 0.15
18 INT315388 Binding of Adcyap1r1 and Adcyap1 1 0.02 0.5 0.12
19 INT236043 ADCYAP1 Positive_regulation of VIPR1 1 0.00 0 0.09
20 INT190750 Adcyap1 Regulation of Positive_regulation of Adcyap1r1 1 0.11 0 0.06
21 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0
22 INT310190 Binding of Adcyap1r1 and Smad6 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for vasoactive intestinal polypeptide receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in vasoactive intestinal polypeptide receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63651 Gene_expression of Adcyap1r1 17 0.77 2.57 4.58
2 INT38249 Positive_regulation of VIPR1 9 0.40 2.58 3.96
3 INT81188 Gene_expression of Vipr2 16 0.78 4.38 3.7
4 INT94181 Gene_expression of VIPR1 7 0.58 0.55 1.79
5 INT25987 Localization of Vipr1 3 0.06 0.43 1.59
6 INT38111 Negative_regulation of VIPR1 3 0.12 3.79 1.45
7 INT60683 Regulation of VIPR1 3 0.07 1.53 1.27
8 INT41143 Localization of VIPR1 4 0.78 1.57 1.16
9 INT41142 Binding of VIPR1 5 0.20 0.07 1.02
10 INT81184 Transcription of Vipr2 2 0.19 0.74 0.97
11 INT94180 Positive_regulation of Gene_expression of VIPR1 3 0.10 0.61 0.96
12 INT71970 Positive_regulation of Adcyap1r1 6 0.14 0.49 0.84
13 INT81187 Regulation of Vipr2 1 0.27 0.78 0.83
14 INT52373 Positive_regulation of Adcyap1r1 1 0.00 0.3 0.78
15 INT81185 Positive_regulation of Transcription of Vipr2 1 0.11 0.74 0.77
16 INT81186 Positive_regulation of Gene_expression of Vipr2 1 0.12 0.74 0.77
17 INT130611 Positive_regulation of Vipr2 2 0.18 0.26 0.75
18 INT206671 Negative_regulation of Vipr2 7 0.44 0.25 0.68
19 INT262551 Positive_regulation of Localization of Vipr1 1 0.01 0.43 0.62
20 INT130610 Positive_regulation of Positive_regulation of Vipr2 1 0.10 0.26 0.61
21 INT190734 Transcription of Adcyap1r1 1 0.19 0.1 0.6
22 INT202291 Gene_expression of Vipr1 3 0.40 0.47 0.48
23 INT130612 Phosphorylation of Vipr2 1 0.12 0.26 0.45
24 INT2018 Regulation of Adcyap1r1 2 0.44 0.3 0.4
25 INT187216 Positive_regulation of Vipr1 2 0.26 0.53 0.4
26 INT60684 Positive_regulation of Negative_regulation of VIPR1 1 0.13 1.3 0.4
27 INT190725 Regulation of Gene_expression of Adcyap1r1 1 0.13 0 0.32
28 INT265198 Negative_regulation of Gene_expression of Vipr2 3 0.59 1.5 0.31
29 INT60681 Negative_regulation of Regulation of VIPR1 1 0.12 0.9 0.3
30 INT60682 Regulation of Negative_regulation of VIPR1 1 0.07 0.9 0.3
31 INT63649 Positive_regulation of Gene_expression of Adcyap1r1 1 0.03 0.1 0.26
32 INT2017 Negative_regulation of Regulation of Adcyap1r1 1 0.41 0 0.25
33 INT153133 Binding of VIPR2 2 0.35 0 0.21
34 INT139281 Gene_expression of VIPR2 3 0.74 0.88 0.2
35 INT202858 Regulation of Adcyap1r1 1 0.05 0.06 0.04
36 INT349847 Negative_regulation of Adcyap1r1 1 0.42 0.32 0.04
37 INT190992 Positive_regulation of VIPR2 1 0.07 0 0.03
38 INT310175 Binding of Adcyap1r1 1 0.02 0 0
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