GO:0005001

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Name transmembrane receptor protein tyrosine phosphatase activity
Categary Function
Go Slim No
Go Link GO:0005001
Unique Molecular Interactions 53
Total Molecular Interactions 66
Total Single Events 513
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transmembrane receptor protein tyrosine phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported for transmembrane receptor protein tyrosine phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125407 Binding of OPRL1 and PTPRM 1 0.03 0.72 4.67
2 INT321045 Anpep Positive_regulation of Protein_catabolism of Ptpn6 1 0.01 0.22 0.48
3 INT151485 Negative_regulation of Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
4 INT151484 Binding of Ptpn6 and Oprd1 1 0.00 0 0.47
5 INT321047 Anpep Regulation of Negative_regulation of Ptpn6 1 0.01 0.25 0.43
6 INT129768 Binding of LYZ and PTPRC 1 0.34 0.87 0.37
7 INT328043 Binding of PTPRC and Enox2 1 0.00 0.88 0.34
8 INT328044 Positive_regulation of Binding of PTPRC and Enox2 1 0.00 0.89 0.34
9 INT328045 Binding of PTPRC and Tag 1 0.00 0.88 0.34
10 INT222986 PTPRC Positive_regulation of SMN1 1 0.01 0.46 0.26
11 INT222975 PTPRC Positive_regulation of VIM 1 0.05 0.46 0.26
12 INT250536 Ghrh Positive_regulation of Negative_regulation of Ptpn6 1 0.09 0 0.24
13 INT165637 Ptpn6 Negative_regulation of Positive_regulation of Nfkb1 1 0.02 0.57 0.23
14 INT165636 Ptpn6 Regulation of Nfkb1 1 0.01 0.36 0.2
15 INT250537 Ptpn6 Negative_regulation of Igf1 1 0.08 0 0.2
16 INT96559 Binding of PTPRC and KRT20 2 0.33 1.99 0.16
17 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16
18 INT172674 Ptpn6 Negative_regulation of Gene_expression of Plat 1 0.02 1.3 0.16
19 INT153154 OPN1MW Regulation of PTPRF 1 0.03 0.51 0.14
20 INT222783 Binding of MR1 and PTPRC 1 0.00 0.46 0.14
21 INT277984 Negative_regulation of Epo Positive_regulation of Localization of Ptprc 1 0.02 0.77 0.12
22 INT338901 Binding of PECAM1 and PTPN6 1 0.03 0.18 0.1
23 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09
24 INT20959 Binding of PTPRC and Pak1 1 0.01 0.76 0.09
25 INT343794 Binding of F8 and PTPRC 1 0.00 0.69 0.09
26 INT103810 Binding of PTPRC and RPL26 1 0.09 1.01 0.08
27 INT179852 Binding of PTPRC and Ecm1 1 0.00 0 0.05
28 INT276386 Gtf3a Regulation of PTPN6 1 0.00 0.86 0.04
29 INT227072 Binding of LTF and PTPRC 1 0.00 0.51 0.04
30 INT276392 Timp1 Regulation of PTPN6 1 0.02 0.87 0.04
31 INT336639 PTPRC Positive_regulation of Ecm1 1 0.00 0.62 0.04
32 INT336637 Binding of PTPRC and Fn1 1 0.00 0.32 0
33 INT321102 Binding of F5 and PTPRC 1 0.01 0.35 0
34 INT314397 Binding of Ptpn6 and Slc17a7 1 0.05 0 0
35 INT278014 Ptprf Regulation of Localization of Gh 1 0.61 0.31 0
36 INT322546 Negative_regulation of PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
37 INT349219 PTPRC Positive_regulation of Gene_expression of SLC3A2 1 0.11 0.53 0
38 INT314393 Ptpn6 Regulation of 1190002H23Rik 1 0.01 0 0
39 INT314402 Positive_regulation of Ptpn6 Regulation of 1190002H23Rik 1 0.02 0 0
40 INT194924 CD22 Positive_regulation of PTPN6 1 0.05 0.08 0
41 INT314403 Ptpn6 Positive_regulation of Gpsm2 1 0.12 0.07 0
42 INT283199 Binding of DMD and PTPRC 1 0.01 0.82 0
43 INT314398 Ptpn6 Regulation of Gene_expression of Ctbs 1 0.03 0 0
44 INT336640 Binding of PTPRC and Fbln1 1 0.01 0.32 0
45 INT249850 Binding of Ptprc and Cd34 1 0.13 0.48 0
46 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0
47 INT322545 PTPN6 Positive_regulation of Gene_expression of Cdkn1b 1 0.03 0.07 0
48 INT314396 Binding of Ptpn6 and Slc17a6 1 0.05 0 0
49 INT278017 Ptprf Regulation of Igf1 1 0.48 0.31 0
50 INT208517 Binding of PAEP and PTPRC 1 0.02 0 0
51 INT314400 Binding of Ptpn6 and Gpsm2 1 0.07 0 0
52 INT263899 Binding of PTPRC and TMED7-TICAM2 1 0.00 0.85 0
53 INT347957 Binding of PTPRC and Cxcr4 1 0.39 0.37 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for transmembrane receptor protein tyrosine phosphatase activity. They are ordered first by their pain relevance and then by number of times they were reported in transmembrane receptor protein tyrosine phosphatase activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57
2 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06
3 INT9491 Positive_regulation of Ptpn6 11 0.51 2.33 7.32
4 INT50975 Localization of Ptpn6 8 0.65 2.64 5.7
5 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45
6 INT6339 Negative_regulation of Ptpn6 6 0.14 0.71 3.44
7 INT64 Regulation of Ptpn6 12 0.14 2.45 3.17
8 INT321018 Protein_catabolism of Ptpn6 1 0.14 0.52 2.73
9 INT230758 Positive_regulation of Gene_expression of PTPRC 11 0.49 6.04 2.45
10 INT137629 Binding of Ptpn6 10 0.30 0.42 2.15
11 INT49433 Binding of PTPRM 2 0.02 0.26 2.15
12 INT321023 Positive_regulation of Localization of Ptpn6 1 0.07 0.27 2.15
13 INT49432 Gene_expression of PTPRM 2 0.04 0.27 1.87
14 INT38266 Localization of PTPRC 30 0.68 17.05 1.68
15 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59
16 INT29856 Negative_regulation of Positive_regulation of Ptpn6 3 0.38 1.24 1.47
17 INT90771 Positive_regulation of Ptprc 20 0.48 8.43 1.27
18 INT74254 Binding of PTPRC 16 0.36 8.37 1.27
19 INT37253 Negative_regulation of PTPRC 12 0.37 6.13 1.26
20 INT314388 Positive_regulation of Gene_expression of Ptpn6 3 0.11 0.05 1.15
21 INT321016 Regulation of Positive_regulation of Ptpn6 1 0.05 0.05 1.15
22 INT321020 Regulation of Protein_catabolism of Ptpn6 1 0.06 0.05 1.12
23 INT62237 Gene_expression of Ptprf 2 0.65 1.63 1.08
24 INT147464 Binding of Ptprc 13 0.36 15.18 0.98
25 INT294150 Regulation of Gene_expression of PTPRC 6 0.32 3.3 0.88
26 INT321017 Negative_regulation of Protein_catabolism of Ptpn6 1 0.08 0.19 0.63
27 INT6168 Negative_regulation of Regulation of Ptpn6 1 0.15 0 0.62
28 INT60057 Negative_regulation of Localization of Ptpn6 1 0.31 0.39 0.62
29 INT109505 Regulation of Ptprc 3 0.32 2.45 0.58
30 INT267615 Positive_regulation of Localization of PTPRC 3 0.01 3.41 0.46
31 INT151482 Negative_regulation of Binding of Ptpn6 1 0.00 0 0.46
32 INT321009 Regulation of Gene_expression of Ptpn6 1 0.05 0.3 0.43
33 INT321429 Positive_regulation of Gene_expression of PTPN6 1 0.03 1.78 0.41
34 INT168101 Positive_regulation of PTPRF 2 0.45 1.04 0.37
35 INT147463 Positive_regulation of Binding of Ptprc 2 0.35 0.95 0.3
36 INT212615 Localization of PTPRF 2 0.68 0.34 0.28
37 INT80059 Negative_regulation of Ptprc 8 0.41 1.85 0.25
38 INT252757 Negative_regulation of PTPN6 4 0.10 0.74 0.25
39 INT245156 Negative_regulation of Gene_expression of PTPRC 4 0.41 0.89 0.21
40 INT321425 Gene_expression of PTPN6 1 0.03 0.89 0.2
41 INT208524 Regulation of PTPRC 7 0.11 3.22 0.16
42 INT152889 Transcription of PTPRC 1 0.69 0.31 0.16
43 INT96224 Positive_regulation of Ptprf 1 0.11 0.36 0.14
44 INT175046 Negative_regulation of Gene_expression of Ptprc 2 0.30 0.8 0.13
45 INT187313 Regulation of PTPRF 1 0.01 0 0.11
46 INT187312 Regulation of Positive_regulation of PTPRF 1 0.03 0 0.11
47 INT294132 Positive_regulation of Positive_regulation of PTPRC 1 0.18 0.08 0.11
48 INT175042 Localization of Ptprc 2 0.53 1.41 0.09
49 INT252729 Phosphorylation of PTPN6 2 0.03 0.67 0.08
50 INT252746 Phosphorylation of PTPRC 2 0.24 0.41 0.08
51 INT194938 Regulation of PTPN6 2 0.29 0.48 0.08
52 INT321438 Regulation of Binding of PTPRC 1 0.29 0.76 0.08
53 INT276339 Localization of PTPN6 1 0.10 1.31 0.08
54 INT175044 Positive_regulation of Gene_expression of Ptprc 1 0.35 3.61 0.06
55 INT243416 Negative_regulation of Binding of PTPRC 1 0.42 0.45 0.05
56 INT279988 Positive_regulation of Negative_regulation of PTPRC 1 0.01 0.3 0.04
57 INT282314 Negative_regulation of Gene_expression of Ptpn6 2 0.09 0.63 0
58 INT314379 Regulation of Localization of Ptpn6 1 0.10 0.08 0
59 INT175043 Regulation of Gene_expression of Ptprc 1 0.36 0.27 0
60 INT278004 Localization of Ptprf 1 0.68 0.31 0
61 INT259807 Transcription of Ptprc 1 0.04 0.67 0
62 INT218006 Regulation of Regulation of Ptpn6 1 0.05 0.25 0
63 INT194944 Positive_regulation of PTPN6 1 0.06 0.46 0
64 INT175045 Positive_regulation of Positive_regulation of Ptprc 1 0.35 1.35 0
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