GO:0005025

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Name transforming growth factor beta receptor activity, type I
Categary Function
Go Slim No
Go Link GO:0005025
Unique Molecular Interactions 31
Total Molecular Interactions 35
Total Single Events 150
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for transforming growth factor beta receptor activity, type I. They are ordered first by their pain relevance and then by number of times they were reported for transforming growth factor beta receptor activity, type I. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
2 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
3 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
4 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
5 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69
6 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
7 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
8 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
9 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
10 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
11 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25
12 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
13 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
14 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
15 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
16 INT311903 Acvrl1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
17 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
18 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
19 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
20 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
21 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
22 INT275231 Binding of ACVRL1 and AK3 1 0.01 0.72 0
23 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
24 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
25 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0
26 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0
27 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0
28 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0
29 INT337917 Binding of sb and Tgfbr1 1 0.00 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for transforming growth factor beta receptor activity, type I. They are ordered first by their pain relevance and then by number of times they were reported in transforming growth factor beta receptor activity, type I. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
2 INT310167 Gene_expression of Acvrl1 2 0.40 5.47 1.4
3 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
4 INT61643 Gene_expression of ACVRL1 9 0.51 9.04 1.03
5 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
6 INT61642 Binding of ACVRL1 5 0.31 7.03 0.87
7 INT311884 Negative_regulation of Acvrl1 1 0.30 2.16 0.81
8 INT265328 Positive_regulation of Acvrl1 5 0.40 3.18 0.78
9 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
10 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
11 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
12 INT311889 Negative_regulation of Gene_expression of Acvrl1 1 0.22 1.27 0.37
13 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
14 INT311895 Regulation of Positive_regulation of Acvrl1 1 0.23 0.97 0.29
15 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
16 INT139741 Positive_regulation of Gene_expression of ACVRL1 2 0.38 1.33 0.28
17 INT311886 Phosphorylation of Tgfbr1 1 0.40 0.7 0.19
18 INT189590 Positive_regulation of ACVRL1 3 0.08 1.3 0.16
19 INT302662 Negative_regulation of Negative_regulation of TGFBR1 1 0.14 0 0.13
20 INT210224 Localization of Acvrl1 1 0.03 0.33 0.12
21 INT254819 Regulation of Negative_regulation of Tgfbr1 1 0.15 1.2 0.09
22 INT311885 Positive_regulation of Gene_expression of Tgfbr1 2 0.44 0.35 0.06
23 INT265340 Binding of Acvrl1 3 0.30 0.46 0
24 INT265316 Binding of Tgfbr1 2 0.35 0.59 0
25 INT265326 Regulation of Tgfbr1 2 0.43 0.17 0
26 INT310166 Regulation of Acvrl1 1 0.07 0 0
27 INT315214 Negative_regulation of Regulation of Tgfbr1 1 0.41 0 0
28 INT268388 Positive_regulation of Positive_regulation of TGFBR1 1 0.35 0.61 0
29 INT310163 Positive_regulation of Positive_regulation of Acvrl1 1 0.08 0 0
30 INT189611 Negative_regulation of Gene_expression of ACVRL1 1 0.06 0.29 0
31 INT297259 Regulation of ACVRL1 1 0.18 0.55 0
32 INT272228 Localization of TGFBR1 1 0.34 0.74 0
33 INT265319 Positive_regulation of Negative_regulation of Tgfbr1 1 0.47 0.53 0
34 INT144920 Positive_regulation of Gene_expression of TGFBR1 1 0.65 0 0
35 INT310176 Localization of Tgfbr1 1 0.11 0.83 0
36 INT310179 Positive_regulation of Positive_regulation of Tgfbr1 1 0.08 0 0
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