GO:0005030

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Name neurotrophin receptor activity
Categary Function
Go Slim No
Go Link GO:0005030
Unique Molecular Interactions 224
Total Molecular Interactions 435
Total Single Events 2228
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for neurotrophin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for neurotrophin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26
2 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33
3 INT131249 Binding of Bdnf and Ntrk2 11 0.41 4 6.25
4 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23
5 INT221746 Ngf Positive_regulation of Ntrk1 1 0.02 0.92 2.88
6 INT106560 Binding of Ntf3 and Ntrk2 3 0.14 2.47 2.84
7 INT67663 Ins1 Positive_regulation of Ntrk2 1 0.00 0.19 2.59
8 INT106558 Binding of Ntrk2 and Ntrk3 3 0.52 2.51 2.28
9 INT161190 CRX Regulation of Gene_expression of Ntrk2 1 0.04 3.05 2.06
10 INT161187 NMS Regulation of Gene_expression of Ntrk2 1 0.43 3.05 2.06
11 INT108385 Binding of Crygs and Ntrk1 1 0.01 0 1.67
12 INT202912 Uchl1 Positive_regulation of Gene_expression of Ntrk2 1 0.08 1.64 1.42
13 INT83197 Binding of Ntrk1 and Gdnf 1 0.01 1.05 1.36
14 INT107104 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.42 1.86 1.34
15 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
16 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
17 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
18 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
19 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
20 INT256041 Binding of Ngfr and Ntrk1 3 0.14 0.9 1.13
21 INT242624 Binding of Ngf and Ntrk2 5 0.24 0.48 1.11
22 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09
23 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09
24 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93
25 INT297463 Binding of Ntrk1 and Ngf 1 0.10 0.78 0.87
26 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87
27 INT298295 Runx1 Negative_regulation of Gene_expression of Ntrk1 2 0.38 0.45 0.86
28 INT256045 Binding of BDNF and Ntrk1 3 0.34 0.65 0.83
29 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79
30 INT78714 Ntrk1 Positive_regulation of Ngf 2 0.50 0.63 0.78
31 INT242626 Binding of Ngf and Ntrk3 3 0.15 0.27 0.77
32 INT351374 Mir470 Negative_regulation of Ntrk3 1 0.00 1.55 0.7
33 INT351375 Mir470 Negative_regulation of Ntrk2 1 0.01 1.54 0.7
34 INT351376 Mir470 Negative_regulation of Ntrk1 1 0.01 1.54 0.7
35 INT161186 Bdnf Regulation of Gene_expression of Ntrk2 1 0.44 1.05 0.68
36 INT142244 Positive_regulation of Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
37 INT142243 Ntrk2 Positive_regulation of Tcrg-C1 1 0.77 0 0.67
38 INT161184 NMS Positive_regulation of Gene_expression of Ntrk2 1 0.55 1.3 0.67
39 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65
40 INT242635 Binding of Bdnf and Ntrk3 3 0.25 0.98 0.64
41 INT298262 Pou4f1 Positive_regulation of Positive_regulation of Ntrk3 1 0.36 0.79 0.63
42 INT90119 Ntrk2 Regulation of Gene_expression of Nfkb1 1 0.01 0.27 0.6
43 INT79740 Ntf3 Regulation of Positive_regulation of Ntrk2 1 0.28 0 0.6
44 INT90115 Ntrk2 Regulation of Jun 1 0.01 0.27 0.57
45 INT242602 Binding of Ntf3 and Ntrk1 1 0.10 0.14 0.57
46 INT298271 Proc Negative_regulation of Gene_expression of Ntrk2 1 0.01 0.79 0.56
47 INT298278 Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.8 0.56
48 INT261481 Positive_regulation of Binding of Bdnf and Ntrk2 1 0.02 0.21 0.56
49 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52
50 INT242631 Binding of Gfra2 and Ntrk1 1 0.01 0 0.52
51 INT193554 Ntrk2 Positive_regulation of Positive_regulation of Ephb1 1 0.01 0.73 0.52
52 INT134533 Binding of Ntrk2 and Psds1 1 0.01 0 0.5
53 INT256040 Ngf Regulation of Gene_expression of Ntrk1 1 0.36 0.73 0.5
54 INT242634 Binding of Gfra1 and Ntrk1 1 0.02 0 0.46
55 INT242596 Binding of Ntrk1 and Ret 1 0.12 0 0.46
56 INT128043 Positive_regulation of Ntrk2 Positive_regulation of Phosphorylation of Trib3 1 0.07 0.34 0.45
57 INT154592 Binding of Ntrk2 and Positive_regulation of Gene_expression of Kcna3 1 0.11 0.16 0.44
58 INT256042 Negative_regulation of Musk Negative_regulation of Ntrk1 1 0.08 0.48 0.44
59 INT298284 Runx3 Negative_regulation of Gene_expression of Ntrk1 1 0.26 0.39 0.43
60 INT298263 Pou4f1 Regulation of Gene_expression of Ntrk1 1 0.34 0.61 0.43
61 INT298287 Runx1 Negative_regulation of Gene_expression of Ntrk3 1 0.32 0.4 0.43
62 INT298291 Runx3 Negative_regulation of Gene_expression of Ntrk3 1 0.32 0.4 0.43
63 INT298270 Gene_expression of Runx1 Positive_regulation of Ntrk3 1 0.35 0.34 0.4
64 INT242607 Negative_regulation of Ntrk1 Positive_regulation of Ret 1 0.16 0 0.39
65 INT298296 Gene_expression of Runx1 Negative_regulation of Gene_expression of Ntrk2 1 0.44 0.33 0.39
66 INT298266 Gene_expression of Runx1 Positive_regulation of Ntrk1 1 0.28 0.34 0.39
67 INT201485 Ntrk2 Positive_regulation of Prkcg 1 0.01 0.73 0.38
68 INT223470 Ret Regulation of Ntrk1 1 0.21 0 0.36
69 INT148241 Binding of Kit and Ntrk1 1 0.25 0.44 0.35
70 INT53127 Binding of Ntrk2 and Ntf4 1 0.12 0 0.33
71 INT129022 Ngf Positive_regulation of Phosphorylation of Ntrk1 1 0.39 0.37 0.31
72 INT242622 Binding of Bdnf and Ntrk1 1 0.05 0.07 0.29
73 INT245554 Tbx15 Positive_regulation of Gene_expression of Ntrk1 1 0.02 0.65 0.29
74 INT245562 Ntrk3 Regulation of Runx3 1 0.40 0.77 0.29
75 INT298297 Pou4f1 Positive_regulation of Gene_expression of Ntrk2 1 0.50 0.36 0.24
76 INT245567 Tbx15 Positive_regulation of Ntrk1 1 0.02 0.9 0.24
77 INT287103 Binding of FL and Ntrk2 1 0.28 0.67 0.24
78 INT298290 Pou4f1 Regulation of Gene_expression of Ntrk2 1 0.29 0.48 0.23
79 INT154591 Binding of Ntrk2 and Positive_regulation of Kcna3 1 0.11 0.08 0.22
80 INT308650 Binding of nt and Ntrk2 1 0.01 0.41 0.21
81 INT298275 Binding of Runx3 and Ntrk2 1 0.37 0.16 0.21
82 INT47694 sps Regulation of Ntrk2 1 0.00 0.98 0.2
83 INT287100 FL Positive_regulation of Ntrk2 1 0.30 0.61 0.2
84 INT280473 Binding of Ntrk1 and Ntf4 1 0.00 0.13 0.2
85 INT223477 Binding of Ntrk1 and Ntrk3 2 0.16 0.3 0.19
86 INT298294 Gene_expression of Runx3 Negative_regulation of Ntrk2 1 0.39 0.16 0.19
87 INT154593 Ntrk2 Regulation of Kcna3 1 0.06 0.06 0.19
88 INT287097 T Positive_regulation of Ntrk2 1 0.21 0.6 0.19
89 INT280485 Ntrk2 Positive_regulation of Localization of Bdnf 1 0.55 0.45 0.19
90 INT280486 Binding of Ngfr and Ntrk2 2 0.18 1.21 0.17
91 INT320259 Binding of Ntrk2 and Atf3 1 0.01 0.38 0.17
92 INT320263 Binding of Ntrk2 and Atf4 1 0.01 0.38 0.17
93 INT298288 Negative_regulation of Runx3 Positive_regulation of Negative_regulation of Ntrk3 1 0.35 0.27 0.17
94 INT298265 Runx3 Negative_regulation of Gene_expression of Ntrk2 1 0.61 0.25 0.17
95 INT298293 Runx1 Positive_regulation of Negative_regulation of Ntrk2 1 0.52 0.54 0.16
96 INT298256 Runx1 Positive_regulation of Negative_regulation of Ntrk1 1 0.30 0.55 0.16
97 INT349861 Gfra1 Negative_regulation of Ntrk1 1 0.01 0.36 0.15
98 INT245566 Runx1 Negative_regulation of Ntrk1 1 0.39 0.65 0.15
99 INT349859 Gfra2 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
100 INT349862 Gfra3 Negative_regulation of Ntrk1 1 0.02 0.3 0.15
101 INT201728 Ntrk1 Regulation of Transcription of App 1 0.03 0.39 0.15
102 INT300861 Ngf Positive_regulation of Ntrk2 1 0.29 0.27 0.15
103 INT223475 Binding of Ntrk1 and Ntrk2 2 0.22 0.25 0.14
104 INT321181 Binding of Ntrk2 and Ntf5 1 0.09 0.08 0.14
105 INT320261 Binding of Myc and Ntrk2 1 0.01 0.36 0.13
106 INT349858 Binding of Ngfr and Ntrk2 1 0.09 0.32 0.11
107 INT280893 Gene_expression of Runx1 Positive_regulation of Gene_expression of Ntrk1 1 0.33 0.44 0.1
108 INT280492 Ntrk1 Regulation of Protein_catabolism of BDNF 1 0.03 0.14 0.1
109 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09
110 INT340318 Gopc Regulation of Ntrk2 1 0.24 0.1 0.08
111 INT23780 Ntrk3 Positive_regulation of Localization of Prl 1 0.11 0 0.08
112 INT300869 Ntrk2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.16 0.08
113 INT215188 Binding of Ntrk2 and Nnat 1 0.00 0.15 0.07
114 INT280894 Runx1 Positive_regulation of Transcription of Ntrk1 1 0.38 0.36 0.07
115 INT270705 Negative_regulation of Bdnf Positive_regulation of Ntrk2 1 0.22 0 0.05
116 INT257878 Ins1 Positive_regulation of Gene_expression of Ntrk2 1 0.00 0.65 0.04
117 INT307462 Gsk3a Regulation of Ntrk2 1 0.04 0.09 0.04
118 INT257877 Ins1 Positive_regulation of Phosphorylation of Ntrk2 1 0.00 0.66 0.04
119 INT307456 Bdnf Positive_regulation of Transcription of Ntrk2 1 0.14 0.25 0.04
120 INT307461 Bdnf Positive_regulation of Ntrk2 1 0.19 0.25 0.04
121 INT321178 Binding of Ntrk2 and Mgst1 1 0.07 0 0.03
122 INT85473 Ntrk2 Regulation of Gene_expression of Pdyn 1 0.01 0.38 0.03
123 INT121225 Positive_regulation of Ngf Positive_regulation of Ntrk1 2 0.49 0 0
124 INT307458 Ntrk2 Positive_regulation of Phosphorylation of Gsk3a 1 0.05 0 0
125 INT321180 Ntrk2 Regulation of Ntrk1 1 0.16 0 0
126 INT321179 Negative_regulation of Binding of Bdnf and Ntrk2 1 0.38 0 0
127 INT223479 Binding of Ntrk2 and Dok5 1 0.26 0.17 0
128 INT210873 Binding of Ntrk2 and Adarb1 1 0.00 0 0
129 INT124074 Binding of Ntrk1 and Ugt1a10 1 0.06 0 0
130 INT65173 Negative_regulation of Ntrk2 Negative_regulation of Bdnf 1 0.37 0 0
131 INT223478 Binding of Ntrk1 and Dok5 1 0.18 0.17 0
132 INT223476 Binding of Ntrk3 and Dok5 1 0.20 0.17 0
133 INT340319 Ntrk2 Regulation of Gopc 1 0.24 0.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for neurotrophin receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in neurotrophin receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28
2 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68
3 INT102902 Gene_expression of Ntrk2 152 0.78 81.52 39.43
4 INT50970 Positive_regulation of Ntrk1 51 0.57 29.38 22.83
5 INT99237 Gene_expression of Ntrk3 84 0.77 38.68 20.77
6 INT47689 Positive_regulation of Ntrk2 44 0.68 16.84 19.59
7 INT50972 Negative_regulation of Ntrk1 39 0.51 32.22 17.29
8 INT66039 Positive_regulation of Ntrk2 53 0.69 15.87 17.23
9 INT65172 Negative_regulation of Ntrk2 35 0.59 9.89 13.08
10 INT108384 Binding of Ntrk1 28 0.39 10.73 9.09
11 INT67116 Gene_expression of Ntrk3 20 0.59 7.64 8.94
12 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75
13 INT47682 Transcription of Ntrk2 19 0.69 6.32 8.6
14 INT50973 Negative_regulation of Gene_expression of Ntrk1 22 0.56 11.12 7.38
15 INT47691 Positive_regulation of Gene_expression of Ntrk2 17 0.62 13.64 6.96
16 INT129020 Phosphorylation of Ntrk1 17 0.80 5.97 6.37
17 INT47681 Regulation of Ntrk2 17 0.62 3.61 6.31
18 INT106552 Positive_regulation of Gene_expression of Ntrk2 19 0.68 9.72 5.51
19 INT107103 Negative_regulation of Ntrk2 21 0.59 10.38 5.28
20 INT106555 Binding of Ntrk2 15 0.48 6.31 5.05
21 INT65056 Binding of Ntrk2 20 0.36 3.72 4.42
22 INT81750 Regulation of Ntrk1 13 0.52 6.03 4.37
23 INT122882 Regulation of Ntrk2 13 0.62 9.7 4.3
24 INT47686 Regulation of Gene_expression of Ntrk2 5 0.44 5.24 4.14
25 INT200047 Negative_regulation of Gene_expression of Ntrk2 8 0.56 10.78 3.95
26 INT134527 Phosphorylation of Ntrk2 7 0.69 3.72 3.65
27 INT298246 Positive_regulation of Ntrk3 7 0.48 3.81 3.01
28 INT156189 Positive_regulation of Gene_expression of Ntrk1 11 0.49 2.81 2.89
29 INT142237 Phosphorylation of Ntrk2 8 0.82 2.24 2.82
30 INT280459 Regulation of Gene_expression of Ntrk2 13 0.62 8.48 2.71
31 INT67621 Negative_regulation of Gene_expression of Ntrk2 7 0.41 2.71 2.52
32 INT47687 Positive_regulation of Transcription of Ntrk2 5 0.45 2.42 2.24
33 INT107102 Negative_regulation of Positive_regulation of Ntrk2 6 0.54 1.61 2.21
34 INT122881 Negative_regulation of Ntrk3 10 0.51 5.52 2.04
35 INT223447 Regulation of Gene_expression of Ntrk1 7 0.34 1.29 1.82
36 INT162454 Positive_regulation of Gene_expression of Ntrk3 3 0.69 4.28 1.74
37 INT200051 Negative_regulation of Gene_expression of Ntrk3 4 0.40 3.55 1.6
38 INT326192 Negative_regulation of Binding of Ntrk2 1 0.10 1 1.47
39 INT142241 Positive_regulation of Positive_regulation of Ntrk2 3 0.66 0.87 1.43
40 INT129017 Negative_regulation of Phosphorylation of Ntrk1 3 0.41 1.5 1.42
41 INT245532 Negative_regulation of Positive_regulation of Ntrk1 2 0.34 1.56 1.34
42 INT245544 Localization of Ntrk2 7 0.77 4.52 1.32
43 INT124069 Localization of Ntrk1 9 0.59 3.32 1.13
44 INT242519 Localization of Ntrk3 3 0.52 3.32 1.08
45 INT242562 Binding of Ntrk3 4 0.26 1.34 0.99
46 INT214113 Transcription of Ntrk2 2 0.72 1.84 0.96
47 INT67117 Negative_regulation of Gene_expression of Ntrk3 1 0.30 0.24 0.96
48 INT138941 Regulation of Transcription of Ntrk2 2 0.47 0.76 0.95
49 INT201635 Positive_regulation of Positive_regulation of Ntrk1 3 0.40 1.15 0.85
50 INT228443 Regulation of Positive_regulation of Ntrk2 3 0.22 0.81 0.84
51 INT67115 Transcription of Ntrk3 1 0.37 0.19 0.81
52 INT67118 Regulation of Gene_expression of Ntrk3 1 0.31 0.17 0.79
53 INT107101 Positive_regulation of Negative_regulation of Ntrk2 1 0.46 0.56 0.77
54 INT82071 Regulation of Ntrk3 1 0.14 0.25 0.76
55 INT228439 Positive_regulation of Regulation of Ntrk2 1 0.01 0.28 0.76
56 INT142239 Regulation of Phosphorylation of Ntrk2 1 0.45 0 0.74
57 INT122880 Regulation of Ntrk3 4 0.43 1.89 0.66
58 INT298240 Regulation of Positive_regulation of Ntrk3 1 0.31 0.78 0.62
59 INT150459 Positive_regulation of Phosphorylation of Ntrk2 2 0.42 0.24 0.52
60 INT69892 Regulation of Regulation of Ntrk2 1 0.62 0.14 0.49
61 INT47688 Negative_regulation of Positive_regulation of Ntrk2 2 0.41 1.79 0.47
62 INT97723 Negative_regulation of Regulation of Ntrk1 1 0.37 0.52 0.45
63 INT228438 Negative_regulation of Regulation of Ntrk2 1 0.00 0.05 0.42
64 INT297454 Negative_regulation of Negative_regulation of Ntrk1 1 0.09 0.23 0.41
65 INT242553 Positive_regulation of Negative_regulation of Ntrk1 1 0.21 0 0.39
66 INT128040 Positive_regulation of Binding of Ntrk2 1 0.49 0.32 0.37
67 INT237469 Positive_regulation of Ntrk3 1 0.46 0.05 0.34
68 INT242533 Positive_regulation of Binding of Ntrk3 1 0.24 0 0.29
69 INT244625 Negative_regulation of Localization of Ntrk1 1 0.04 0.56 0.28
70 INT69891 Positive_regulation of Negative_regulation of Ntrk2 1 0.50 0.08 0.26
71 INT206803 Positive_regulation of Positive_regulation of Ntrk2 4 0.15 1.78 0.24
72 INT280460 Positive_regulation of Localization of Ntrk1 2 0.11 0.32 0.21
73 INT235325 Positive_regulation of Localization of Ntrk2 2 0.23 0.2 0.19
74 INT242558 Transcription of Ntrk1 2 0.37 0.66 0.17
75 INT280469 Regulation of Localization of Ntrk2 1 0.43 1.74 0.14
76 INT256032 Phosphorylation of Ntrk3 2 0.39 0.61 0.12
77 INT242544 Positive_regulation of Transcription of Ntrk1 1 0.29 0.3 0.1
78 INT167518 Regulation of Localization of Ntrk2 1 0.01 0.1 0.08
79 INT307478 Negative_regulation of Transcription of Ntrk2 1 0.18 0.13 0.07
80 INT321173 Positive_regulation of Phosphorylation of Ntrk2 1 0.50 0.19 0.06
81 INT351372 Regulation of Localization of Ntrk1 1 0.34 0.92 0
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